Lista de obras -

A transcriptome-wide Mendelian randomization study to uncover tissue-dependent regulatory mechanisms across the human phenome

scientific article published on 10 January 2020

An atlas of polygenic risk score associations to highlight putative causal relationships across the human phenome

An integrative approach to detect epigenetic mechanisms that putatively mediate the influence of lifestyle exposures on disease susceptibility

artículo científico publicado en 2019

Characterising metabolomic signatures of lipid-modifying therapies through drug target mendelian randomisation

artículo científico publicado en 2022

Collapsed methylation quantitative trait loci analysis for low frequency and rare variants

artículo científico publicado en 2016

Conditioning on a Collider May Induce Spurious Associations: Do the Results of Gale et al. (2017) Support a Health-Protective Effect of Neuroticism in Population Subgroups?

article

Effects of apolipoprotein B on lifespan and risks of major diseases including type 2 diabetes: a mendelian randomisation analysis using outcomes in first-degree relatives

artículo científico publicado en 2021

Evaluating the direct effects of childhood adiposity on adult systemic metabolism: a multivariable Mendelian randomization analysis

artículo científico publicado en 2021

Evaluating the effects of cardiometabolic exposures on circulating proteins which may contribute to severe SARS-CoV-2

artículo científico publicado en 2021

Evaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: A multivariable Mendelian randomisation analysis

artículo científico publicado en 2020

Evaluating the role of a galanin enhancer genotype on a range of metabolic, depressive and addictive phenotypes.

artículo científico publicado en 2014

Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation

artículo científico publicado en 2021

Harnessing Whole Genome Polygenic Risk Scores to Stratify Individuals Based on Cardiometabolic Risk Factors and Biomarkers at Age 10 in the Lifecourse-Brief Report

artículo científico publicado en 2022

Hypertensive Disorders of Pregnancy and DNA Methylation in Newborns

scientific article published on 24 June 2019

Identifying drug targets for neurological and psychiatric disease via genetics and the brain transcriptome

artículo científico publicado en 2021

Influence of adiposity-related genetic markers in a population of saudi arabians where other variables influencing obesity may be reduced

artículo científico publicado en 2014

Integrating Mendelian randomization and multiple-trait colocalization to uncover cell-specific inflammatory drivers of autoimmune and atopic disease

scientific article published on 01 October 2019

Integrative multiomics analysis highlights immune-cell regulatory mechanisms and shared genetic architecture for 14 immune-associated diseases and cancer outcomes

artículo científico publicado en 2021

Investigating causal pathways between liability to ADHD and substance use, and liability to substance use and ADHD risk, using Mendelian randomization.: Supplemental material

Investigating causality between liability to ADHD and substance use, and liability to substance use and ADHD risk, using Mendelian randomization

scientific article published on 16 November 2019

Investigation of the Interplay between Circulating Lipids and IGF-I and Relevance to Breast Cancer Risk: An Observational and Mendelian Randomization Study

artículo científico publicado en 2021

Leveraging brain cortex-derived molecular data to elucidate epigenetic and transcriptomic drivers of complex traits and disease

Mendelian Randomization Analysis Identifies CpG Sites as Putative Mediators for Genetic Influences on Cardiovascular Disease Risk.

artículo científico publicado en 2017

Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight

article

PhenoSpD: an integrated toolkit for phenotypic correlation estimation and multiple testing correction using GWAS summary statistics

artículo científico publicado en 2018

Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases

artículo científico publicado en 2020

Smoking, DNA Methylation, and Lung Function: a Mendelian Randomization Analysis to Investigate Causal Pathways

scientific article published on 20 February 2020

Use of genetic variation to separate the effects of early and later life adiposity on disease risk: mendelian randomisation study

scientific article published on 06 May 2020

Using Y-Chromosomal Haplogroups in Genetic Association Studies and Suggested Implications

artículo científico publicado en 2018

Lista de obras de

A transcriptome-wide Mendelian randomization study to uncover tissue-dependent regulatory mechanisms across the human phenome

A transcriptome-wide Mendelian randomization study to uncover tissue-dependent regulatory mechanisms across the human phenome

An atlas of polygenic risk score associations to highlight putative causal relationships across the human phenome

An integrative approach to detect epigenetic mechanisms that putatively mediate the influence of lifestyle exposures on disease susceptibility

Characterising metabolomic signatures of lipid-modifying therapies through drug target mendelian randomisation

Collapsed methylation quantitative trait loci analysis for low frequency and rare variants

Conditioning on a Collider May Induce Spurious Associations: Do the Results of Gale et al. (2017) Support a Health-Protective Effect of Neuroticism in Population Subgroups?

Effects of apolipoprotein B on lifespan and risks of major diseases including type 2 diabetes: a mendelian randomisation analysis using outcomes in first-degree relatives

Evaluating the direct effects of childhood adiposity on adult systemic metabolism: a multivariable Mendelian randomization analysis

Evaluating the effects of cardiometabolic exposures on circulating proteins which may contribute to severe SARS-CoV-2

Evaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: A multivariable Mendelian randomisation analysis

Evaluating the role of a galanin enhancer genotype on a range of metabolic, depressive and addictive phenotypes.

Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation

Harnessing Whole Genome Polygenic Risk Scores to Stratify Individuals Based on Cardiometabolic Risk Factors and Biomarkers at Age 10 in the Lifecourse-Brief Report

Hypertensive Disorders of Pregnancy and DNA Methylation in Newborns

Identifying drug targets for neurological and psychiatric disease via genetics and the brain transcriptome

Influence of adiposity-related genetic markers in a population of saudi arabians where other variables influencing obesity may be reduced

Integrating Mendelian randomization and multiple-trait colocalization to uncover cell-specific inflammatory drivers of autoimmune and atopic disease

Integrative multiomics analysis highlights immune-cell regulatory mechanisms and shared genetic architecture for 14 immune-associated diseases and cancer outcomes

Investigating causal pathways between liability to ADHD and substance use, and liability to substance use and ADHD risk, using Mendelian randomization.: Supplemental material

Investigating causality between liability to ADHD and substance use, and liability to substance use and ADHD risk, using Mendelian randomization

Investigation of the Interplay between Circulating Lipids and IGF-I and Relevance to Breast Cancer Risk: An Observational and Mendelian Randomization Study

Leveraging brain cortex-derived molecular data to elucidate epigenetic and transcriptomic drivers of complex traits and disease

Mendelian Randomization Analysis Identifies CpG Sites as Putative Mediators for Genetic Influences on Cardiovascular Disease Risk.

Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight

PhenoSpD: an integrated toolkit for phenotypic correlation estimation and multiple testing correction using GWAS summary statistics

Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases

Smoking, DNA Methylation, and Lung Function: a Mendelian Randomization Analysis to Investigate Causal Pathways

Use of genetic variation to separate the effects of early and later life adiposity on disease risk: mendelian randomisation study

Using Y-Chromosomal Haplogroups in Genetic Association Studies and Suggested Implications