Lista de obras - Mark Blaskovich - Dominio Público Uruguay

A new antibiotic with potent activity targets MscL.

artículo científico publicado en 2015

Activity and Predicted Nephrotoxicity of Synthetic Antibiotics Based on Polymyxin B.

artículo científico publicado en 2016

An amphipathic peptide with antibiotic activity against multidrug-resistant Gram-negative bacteria

artículo científico publicado en 2020

An azido-oxazolidinone antibiotic for live bacterial cell imaging and generation of antibiotic variants

artículo científico publicado en 2014

Anti-cooperative ligand binding and dimerisation in the glycopeptide antibiotic dalbavancin

artículo científico publicado en 2014

Antibacterial serrulatane diterpenes from the Australian native plant Eremophila microtheca.

artículo científico publicado en 2013

Antibiotics in the clinical pipeline at the end of 2015.

artículo científico publicado en 2016

Antibiotics in the clinical pipeline in 2013.

artículo científico

Antimicrobial Silver in Medicinal and Consumer Applications: A Patent Review of the Past Decade (2007⁻2017)

article

Antitubercular and Antiparasitic 2-Nitroimidazopyrazinones with Improved Potency and Solubility

artículo científico publicado en 2020

Can octapeptin antibiotics combat extensively drug-resistant (XDR) bacteria?

artículo científico publicado en 2018

Cell- and biomarker-based assays for predicting nephrotoxicity

artículo científico publicado en 2014

Chemical philanthropy: a path forward for antibiotic discovery?

artículo científico publicado en 2016

Chemical synthesis of human trefoil factor 1 (TFF1) and its homodimer provides novel insights into their mechanisms of action

scientific article published on 11 May 2020

Clostridium difficile drug pipeline: challenges in discovery and development of new agents

artículo científico publicado en 2015

Contribution of Amphipathicity and Hydrophobicity to the Antimicrobial Activity and Cytotoxicity of β-Hairpin Peptides

artículo científico publicado en 2016

Correction: Chemical synthesis of human trefoil factor 1 (TFF1) and its homodimer provides novel insights into their mechanisms of action

scientific article published on 17 June 2020

Cover Feature: Nontoxic Cobalt(III) Schiff Base Complexes with Broad‐Spectrum Antifungal Activity (Chem. Eur. J. 6/2021)

artículo científico publicado en 2020

CryoEM structure of the outer membrane secretin channel pIV from the f1 filamentous bacteriophage

artículo científico publicado en 2021

Design and synthesis of phosphotyrosine mimetics.

artículo científico publicado en 2003

Design, synthesis and biological evaluation of 2-nitroimidazopyrazin-one/-es with antitubercular and antiparasitic activity

artículo científico publicado en 2018

Detection and Investigation of Eagle Effect Resistance to Vancomycin in Clostridium difficile With an ATP-Bioluminescence Assay.

artículo científico publicado en 2018

Developments in Glycopeptide Antibiotics

artículo científico publicado en 2018

Discovery of functionally selective C5aR2 ligands: novel modulators of C5a signalling.

artículo científico publicado en 2016

Drug discovery and protein tyrosine phosphatases.

artículo científico publicado en 2009

Effects of Microplate Type and Broth Additives on Microdilution MIC Susceptibility Assays

artículo científico publicado en 2018

Elucidating the Lipid Binding Properties of Membrane-Active Peptides Using Cyclised Nanodiscs

scientific article published on 16 April 2019

Enhancement of antibiotic-activity through complexation with metal ions - Combined ITC, NMR, enzymatic and biological studies.

artículo científico publicado en 2016

Evaluation of biomarkers for in vitro prediction of drug-induced nephrotoxicity: comparison of HK-2, immortalized human proximal tubule epithelial, and primary cultures of human proximal tubular cells

artículo científico publicado en 2015

Fluorescent Antibiotics: New Research Tools to Fight Antibiotic Resistance.

artículo científico publicado en 2018

Fluorescent Trimethoprim Conjugate Probes To Assess Drug Accumulation in Wild Type and Mutant Escherichia coli

artículo científico publicado en 2016

Fluoroquinolone-derived fluorescent probes for studies of bacterial penetration and efflux

artículo científico publicado en 2019

Glycopeptide antibiotics: back to the future.

artículo científico publicado en 2014

Helping Chemists Discover New Antibiotics.

artículo científico publicado en 2015

Highly efficient and versatile synthesis of libraries of constrained beta-strand mimetics

artículo científico publicado en 1998

How to Stimulate and Facilitate Early Stage Antibiotic Discovery

scientific article published on 01 June 2020

In vitro Antimicrobial Activity of Acne Drugs Against Skin-Associated Bacteria

artículo científico publicado en 2019

Institutional profile: Community for Open Antimicrobial Drug Discovery - crowdsourcing new antibiotics and antifungals

artículo científico publicado en 2017

Investigating the Interaction of Octapeptin A3 with Model Bacterial Membranes

artículo científico publicado en 2017

Light-Activated Rhenium Complexes with Dual Mode of Action against Bacteria

scientific article published on 30 January 2020

Lipoamino acids as major components of absorption promoters in drug delivery.

artículo científico

Loss of YhcB results in dysregulation of coordinated peptidoglycan, LPS and phospholipid synthesis during Escherichia coli cell growth

artículo científico publicado en 2021

Loss of β-Ketoacyl Acyl Carrier Protein Synthase III Activity Restores Multidrug-Resistant Escherichia coli Sensitivity to Previously Ineffective Antibiotics

artículo científico publicado en 2022

Metal Complexes as Antifungals? From a Crowd-Sourced Compound Library to the First <i>In Vivo</i> Experiments

artículo científico publicado en 2022

Metal complexes as a promising source for new antibiotics

artículo científico publicado en 2020

Metronidazole-triazole conjugates: activity against Clostridium difficile and parasites

artículo científico publicado en 2015

Mucin Binding Reduces Colistin Antimicrobial Activity.

artículo científico publicado en 2015

Multifactorial Chromosomal Variants Regulate Polymyxin Resistance In Extensively Drug-Resistant Klebsiella pneumoniae

Multifactorial chromosomal variants regulate polymyxin resistance in extensively drug-resistant Klebsiella pneumoniae

artículo científico publicado en 2018

Natural products as anthelmintics: safeguarding animal health

artículo científico publicado en 2023

Nitroimidazole carboxamides as antiparasitic agents targeting Giardia lamblia, Entamoeba histolytica and Trichomonas vaginalis.

artículo científico publicado en 2016

Nitroimidazoles: Molecular Fireworks That Combat a Broad Spectrum of Infectious Diseases.

artículo científico publicado en 2017

Non-antibiotic Small-Molecule Regulation of DHFR-Based Destabilizing Domains In Vivo

artículo científico publicado en 2019

Non-toxic Cobalt(III) Schiff Base Complexes with Broad Spectrum Antifungal Activity

artículo científico publicado en 2020

Nontoxic Cobalt(III) Schiff Base Complexes with Broad-Spectrum Antifungal Activity

artículo científico publicado en 2020

Octapeptin C4 Induces Less Resistance and Novel Mutations in an Epidemic Carbapenemase-producing Klebsiella pneumoniae ST258 Clinical Isolate Compared to Polymyxins

article by Miranda Pitt et al published 28 April 2018 in bioRxiv

Octapeptin C4 and polymyxin resistance occur via distinct pathways in an epidemic XDR Klebsiella pneumoniae ST258 isolate

scientific article published on 01 March 2019

Old dogs and new tricks in antimicrobial discovery.

artículo científico publicado en 2016

Polishing the tarnished silver bullet: the quest for new antibiotics

artículo científico publicado en 2017

Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria.

artículo científico publicado en 2018

Quinolone antibiotics

scientific article published on 28 June 2019

Repurposing a neurodegenerative disease drug to treat Gram-negative antibiotic-resistant bacterial sepsis

artículo científico publicado en 2020

Resolving biofilm infections: current therapy and drug discovery strategies.

artículo científico publicado en 2012

Self-assembling lipopeptides with a potent activity against Gram-positive bacteria, including multidrug resistant strains.

artículo científico publicado en 2015

Short cationic lipopeptides as effective antibacterial agents: Design, physicochemical properties and biological evaluation.

artículo científico publicado en 2016

Silver bullets: A new lustre on an old antimicrobial agent

artículo científico publicado en 2018

Structure, Function, and Biosynthetic Origin of Octapeptin Antibiotics Active against Extensively Drug-Resistant Gram-Negative Bacteria.

artículo científico publicado en 2018

Structure-Activity and -Toxicity Relationships of the Antimicrobial Peptide Tachyplesin-1.

artículo científico publicado en 2017

Structure-Function Studies of Polymyxin B Lipononapeptides

artículo científico publicado en 2019

Surface Ligand Density of Antibiotic-Nanoparticle Conjugates Enhances Target Avidity and Membrane Permeabilization of Vancomycin-Resistant Bacteria.

artículo científico publicado en 2016

Synthesis of octapeptin C4 and biological profiling against NDM-1 and polymyxin-resistant bacteria.

artículo científico publicado en 2017

The Eagle Effect and Antibiotic-Induced Persistence: Two Sides of the Same Coin?

scientific article published on 15 November 2018

The Fight Against Antimicrobial Resistance Is Confounded by a Global Increase in Antibiotic Usage

scientific article published on 14 May 2018

Tyrosinase inhibitors as potential antibacterial agents

artículo científico publicado en 2019

Unusual Amino Acids in Medicinal Chemistry

artículo científico publicado en 2016

Lista de obras de Mark Blaskovich

A new antibiotic with potent activity targets MscL.

Activity and Predicted Nephrotoxicity of Synthetic Antibiotics Based on Polymyxin B.

An amphipathic peptide with antibiotic activity against multidrug-resistant Gram-negative bacteria

An azido-oxazolidinone antibiotic for live bacterial cell imaging and generation of antibiotic variants

Anti-cooperative ligand binding and dimerisation in the glycopeptide antibiotic dalbavancin

Antibacterial serrulatane diterpenes from the Australian native plant Eremophila microtheca.

Antibiotics in the clinical pipeline at the end of 2015.

Antibiotics in the clinical pipeline in 2013.

Antimicrobial Silver in Medicinal and Consumer Applications: A Patent Review of the Past Decade (2007⁻2017)

Antitubercular and Antiparasitic 2-Nitroimidazopyrazinones with Improved Potency and Solubility

Can octapeptin antibiotics combat extensively drug-resistant (XDR) bacteria?

Cell- and biomarker-based assays for predicting nephrotoxicity

Chemical philanthropy: a path forward for antibiotic discovery?

Chemical synthesis of human trefoil factor 1 (TFF1) and its homodimer provides novel insights into their mechanisms of action

Clostridium difficile drug pipeline: challenges in discovery and development of new agents

Contribution of Amphipathicity and Hydrophobicity to the Antimicrobial Activity and Cytotoxicity of β-Hairpin Peptides

Correction: Chemical synthesis of human trefoil factor 1 (TFF1) and its homodimer provides novel insights into their mechanisms of action

Cover Feature: Nontoxic Cobalt(III) Schiff Base Complexes with Broad‐Spectrum Antifungal Activity (Chem. Eur. J. 6/2021)

CryoEM structure of the outer membrane secretin channel pIV from the f1 filamentous bacteriophage

CryoEM structure of the outer membrane secretin channel pIV from the f1 filamentous bacteriophage

Design and synthesis of phosphotyrosine mimetics.

Design, synthesis and biological evaluation of 2-nitroimidazopyrazin-one/-es with antitubercular and antiparasitic activity

Detection and Investigation of Eagle Effect Resistance to Vancomycin in Clostridium difficile With an ATP-Bioluminescence Assay.

Developments in Glycopeptide Antibiotics

Discovery of functionally selective C5aR2 ligands: novel modulators of C5a signalling.

Drug discovery and protein tyrosine phosphatases.

Effects of Microplate Type and Broth Additives on Microdilution MIC Susceptibility Assays

Elucidating the Lipid Binding Properties of Membrane-Active Peptides Using Cyclised Nanodiscs

Enhancement of antibiotic-activity through complexation with metal ions - Combined ITC, NMR, enzymatic and biological studies.

Evaluation of biomarkers for in vitro prediction of drug-induced nephrotoxicity: comparison of HK-2, immortalized human proximal tubule epithelial, and primary cultures of human proximal tubular cells

Fluorescent Antibiotics: New Research Tools to Fight Antibiotic Resistance.

Fluorescent Trimethoprim Conjugate Probes To Assess Drug Accumulation in Wild Type and Mutant Escherichia coli

Fluoroquinolone-derived fluorescent probes for studies of bacterial penetration and efflux

Glycopeptide antibiotics: back to the future.

Helping Chemists Discover New Antibiotics.

Highly efficient and versatile synthesis of libraries of constrained beta-strand mimetics

How to Stimulate and Facilitate Early Stage Antibiotic Discovery

In vitro Antimicrobial Activity of Acne Drugs Against Skin-Associated Bacteria

Institutional profile: Community for Open Antimicrobial Drug Discovery - crowdsourcing new antibiotics and antifungals

Investigating the Interaction of Octapeptin A3 with Model Bacterial Membranes

Light-Activated Rhenium Complexes with Dual Mode of Action against Bacteria

Lipoamino acids as major components of absorption promoters in drug delivery.

Loss of YhcB results in dysregulation of coordinated peptidoglycan, LPS and phospholipid synthesis during Escherichia coli cell growth

Loss of β-Ketoacyl Acyl Carrier Protein Synthase III Activity Restores Multidrug-Resistant Escherichia coli Sensitivity to Previously Ineffective Antibiotics

Metal Complexes as Antifungals? From a Crowd-Sourced Compound Library to the First <i>In Vivo</i> Experiments

Metal complexes as a promising source for new antibiotics

Metronidazole-triazole conjugates: activity against Clostridium difficile and parasites

Mucin Binding Reduces Colistin Antimicrobial Activity.

Multifactorial Chromosomal Variants Regulate Polymyxin Resistance In Extensively Drug-Resistant Klebsiella pneumoniae

Multifactorial chromosomal variants regulate polymyxin resistance in extensively drug-resistant Klebsiella pneumoniae

Natural products as anthelmintics: safeguarding animal health

Nitroimidazole carboxamides as antiparasitic agents targeting Giardia lamblia, Entamoeba histolytica and Trichomonas vaginalis.

Nitroimidazoles: Molecular Fireworks That Combat a Broad Spectrum of Infectious Diseases.

Non-antibiotic Small-Molecule Regulation of DHFR-Based Destabilizing Domains In Vivo

Non-toxic Cobalt(III) Schiff Base Complexes with Broad Spectrum Antifungal Activity

Nontoxic Cobalt(III) Schiff Base Complexes with Broad-Spectrum Antifungal Activity

Octapeptin C4 Induces Less Resistance and Novel Mutations in an Epidemic Carbapenemase-producing Klebsiella pneumoniae ST258 Clinical Isolate Compared to Polymyxins

Octapeptin C4 and polymyxin resistance occur via distinct pathways in an epidemic XDR Klebsiella pneumoniae ST258 isolate

Old dogs and new tricks in antimicrobial discovery.

Polishing the tarnished silver bullet: the quest for new antibiotics

Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria.

Quinolone antibiotics

Repurposing a neurodegenerative disease drug to treat Gram-negative antibiotic-resistant bacterial sepsis

Resolving biofilm infections: current therapy and drug discovery strategies.

Self-assembling lipopeptides with a potent activity against Gram-positive bacteria, including multidrug resistant strains.

Short cationic lipopeptides as effective antibacterial agents: Design, physicochemical properties and biological evaluation.

Silver bullets: A new lustre on an old antimicrobial agent

Structure, Function, and Biosynthetic Origin of Octapeptin Antibiotics Active against Extensively Drug-Resistant Gram-Negative Bacteria.

Structure-Activity and -Toxicity Relationships of the Antimicrobial Peptide Tachyplesin-1.

Structure-Function Studies of Polymyxin B Lipononapeptides

Surface Ligand Density of Antibiotic-Nanoparticle Conjugates Enhances Target Avidity and Membrane Permeabilization of Vancomycin-Resistant Bacteria.

Synthesis of octapeptin C4 and biological profiling against NDM-1 and polymyxin-resistant bacteria.

The Eagle Effect and Antibiotic-Induced Persistence: Two Sides of the Same Coin?

The Fight Against Antimicrobial Resistance Is Confounded by a Global Increase in Antibiotic Usage

Tyrosinase inhibitors as potential antibacterial agents

Unusual Amino Acids in Medicinal Chemistry