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Lista de obras de Paul Frenette

2011 - ENGINEERING A HEMATOPOIETIC STEM CELL NICHE BY REVITALIZING MESENCHYMAL STEM CELLS

scholarly article

A Time Bomb for Leukemia.

artículo científico publicado en 2016

A non-cell-autonomous role for Pml in the maintenance of leukemia from the niche.

artículo científico publicado en 2018

A novel model for lymphocytic infiltration of the thyroid gland generated by transgenic expression of the CC chemokine CCL21

artículo científico publicado en 2004

A novel role for factor VIII and thrombin/PAR1 in regulating hematopoiesis and its interplay with the bone structure

artículo científico publicado en 2013

Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications : Bamberg, Germany. 23-25 June, 2017

article

Activated Neutrophils Are Associated with Pediatric Cerebral Malaria Vasculopathy in Malawian Children

artículo científico publicado en 2015

Acute myelogenous leukemia-induced sympathetic neuropathy promotes malignancy in an altered hematopoietic stem cell niche

artículo científico publicado en 2014

Adrenergic nerve degeneration in bone marrow drives aging of the hematopoietic stem cell niche

artículo científico publicado en 2018

Adrenergic nerves activate an angio-metabolic switch in prostate cancer.

artículo científico publicado en 2017

Adrenergic nerves govern circadian leukocyte recruitment to tissues.

artículo científico publicado en 2012

An anillin-Ect2 complex stabilizes central spindle microtubules at the cortex during cytokinesis

artículo científico publicado en 2012

Arteriolar niches maintain haematopoietic stem cell quiescence.

artículo científico publicado en 2013

Artery-Associated Sympathetic Innervation Drives Rhythmic Vascular Inflammation of Arteries and Veins

scientific article published on 12 August 2019

Author Correction: Adrenergic nerve degeneration in bone marrow drives aging of the hematopoietic stem cell niche

artículo científico publicado en 2019

Author Correction: The bone marrow microenvironment at single-cell resolution

artículo científico publicado en 2019

Autonomic nerve development contributes to prostate cancer progression

artículo científico publicado en 2013

B cell-driven lymphangiogenesis in inflamed lymph nodes enhances dendritic cell mobilization

artículo científico publicado en 2006

Bad blood: a trigger for TRALI

artículo científico publicado en 2010

Beneficial Effects of Soluble Guanylyl Cyclase Stimulation and Activation in Sickle Cell Disease are Amplified by Hydroxyurea: In Vitro and In Vivo Studies

artículo científico publicado en 2020

Bone Marrow Arteriolar Niches Maintain Hematopoietic Stem Cell Quiescence

scholarly article

Bone marrow CD169+ macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche

artículo científico publicado en 2011

Bone marrow NG2<sup>+</sup>/Nestin<sup>+</sup> mesenchymal stem cells drive DTC dormancy <i>via</i> TGFβ2

artículo científico publicado en 2021

Bone marrow mesenchymal stem and progenitor cells induce monocyte emigration in response to circulating toll-like receptor ligands

artículo científico publicado en 2011

Brain motor and fear circuits regulate leukocytes during acute stress

artículo científico publicado en 2022

CD150high Bone Marrow Tregs Maintain Hematopoietic Stem Cell Quiescence and Immune Privilege via Adenosine

artículo científico publicado en 2018

CD169⁺ macrophages provide a niche promoting erythropoiesis under homeostasis and stress

scientific article published on 17 March 2013

CD44 is a physiological E-selectin ligand on neutrophils

artículo científico publicado en 2005

CXCL1 and its receptor, CXCR2, mediate murine sickle cell vaso-occlusion during hemolytic transfusion reactions

artículo científico publicado en 2011

Chemotherapy-induced bone marrow nerve injury impairs hematopoietic regeneration.

artículo científico publicado en 2013

Cholinergic Signals from the CNS Regulate G-CSF-Mediated HSC Mobilization from Bone Marrow via a Glucocorticoid Signaling Relay.

artículo científico publicado en 2017

Circadian Adrenergic Regulation of Bone Marrow Endothelial Adhesion Molecule Expression Impacts Progenitor Recruitment and Engraftment Efficiency

scholarly article

Circadian control of the immune system

artículo científico publicado en 2013

Circadian rhythms influence hematopoietic stem cells

artículo científico publicado en 2009

Clinically Actional Strategies for Studying Neural Influences in Cancer

artículo científico publicado en 2020

Complete identification of E-selectin ligands on neutrophils reveals distinct functions of PSGL-1, ESL-1, and CD44

artículo científico publicado en 2007

Complexity of bone marrow hematopoietic stem cell niche

artículo científico publicado en 2017

Contributions of Immune Cells to Vascular Occlusion in Sickle Cell Disease.

scholarly article

Cooperation of beta(2)- and beta(3)-adrenergic receptors in hematopoietic progenitor cell mobilization

artículo científico publicado en 2010

Coordinated Regulation of Hematopoietic and Mesenchymal Stem Cells in a Bone Marrow Niche.

scholarly article

Cross talk between neutrophils and the microbiota

artículo científico publicado en 2019

Deciphering the transcriptional network of the dendritic cell lineage

artículo científico publicado en 2012

Diabetes impairs hematopoietic stem cell mobilization by altering niche function

artículo científico publicado en 2011

Dietary Intake Regulates the Circulating Inflammatory Monocyte Pool

scientific article published on 22 August 2019

Differential cytokine contributions of perivascular haematopoietic stem cell niches

artículo científico publicado en 2017

Distinct Contributions By Perivascular Niche Cells in Hematopoietic Stem Cell Maintenance

artículo científico publicado en 2015

Endothelial Jagged-1 is necessary for homeostatic and regenerative hematopoiesis

scientific article published on 05 September 2013

Enforced fucosylation of neonatal CD34+ cells generates selectin ligands that enhance the initial interactions with microvessels but not homing to bone marrow

artículo científico publicado en 2004

Engineering a haematopoietic stem cell niche by revitalizing mesenchymal stromal cells

scientific article published on 15 April 2019

F4/80 Identifies a Subset of Non-Mobilizable Bone Marrow HSCs Involved in Stress-Induced Hematopoiesis

scholarly article

Fetal liver hematopoietic stem cell niches associate with portal vessels

artículo científico publicado en 2015

Functional selectin ligands mediating human CD34(+) cell interactions with bone marrow endothelium are enhanced postnatally.

artículo científico publicado en 2002

GM-CSF controls nonlymphoid tissue dendritic cell homeostasis but is dispensable for the differentiation of inflammatory dendritic cells

artículo científico publicado en 2012

GMI-1070, a novel pan-selectin antagonist, reverses acute vascular occlusions in sickle cell mice

artículo científico publicado en 2010

Galactocerebrosides are required postnatally for stromal-dependent bone marrow lymphopoiesis

scientific article published on 01 June 2003

Galpha(s) uncouples hematopoietic stem cell homing and mobilization.

artículo científico publicado en 2009

Granulocyte-derived TNFα promotes vascular and hematopoietic regeneration in the bone marrow.

artículo científico publicado en 2017

Guidelines for the use of flow cytometry and cell sorting in immunological studies

artículo científico publicado en 2017

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

scientific article published on 01 October 2019

HSC Contribution in Making Steady-State Blood

artículo científico publicado en 2016

Haematopoietic stem cell activity and interactions with the niche

scientific article published on 01 May 2019

Haematopoietic stem cell release is regulated by circadian oscillations

artículo científico publicado en 2008

Hematopoietic stem cell niche maintenance during homeostasis and regeneration

artículo científico publicado en 2014

Hematopoietic stem cell trafficking

artículo científico publicado en 2010

Hematopoietic stem cell trafficking: regulated adhesion and attraction to bone marrow microenvironment

artículo científico publicado en 2007

Heme-Induced Neutrophil Extracellular Traps (NETs) Formation Contributes To Sickle Cell Disease Pathogenesis

artículo científico publicado en 2013

Heme-induced neutrophil extracellular traps contribute to the pathogenesis of sickle cell disease

artículo científico publicado en 2014

Heterotypic interactions enabled by polarized neutrophil microdomains mediate thromboinflammatory injury

artículo científico publicado en 2009

Hydroxyurea and a cGMP-amplifying agent have immediate benefits on acute vaso-occlusive events in sickle cell disease mice

artículo científico publicado en 2012

Identification of a radio-resistant and cycling dermal dendritic cell population in mice and men.

artículo científico publicado en 2006

Identification of the Circulating Langerhans Cell Precursor.

artículo científico publicado en 2005

Imaging receptor microdomains on leukocyte subsets in live mice

artículo científico publicado en 2007

In Situ Hematopoietic Stem Cell Imaging

artículo científico publicado en 2021

Inflammatory exposure drives long-lived impairment of hematopoietic stem cell self-renewal activity and accelerated aging

scientific article published in 2022

Influences of vascular niches on hematopoietic stem cell fate

artículo científico

Insights into leukocyte adhesion deficiency type 2 from a novel mutation in the GDP-fucose transporter gene.

artículo científico publicado en 2002

Integrin alpha4beta7 and its counterreceptor MAdCAM-1 contribute to hematopoietic progenitor recruitment into bone marrow following transplantation

artículo científico publicado en 2004

Intravenous immune globulin prevents venular vaso-occlusion in sickle cell mice by inhibiting leukocyte adhesion and the interactions between sickle erythrocytes and adherent leukocytes

artículo científico publicado en 2003

Intravenous immunoglobulins modulate neutrophil activation and vascular injury through FcγRIII and SHP-1.

artículo científico publicado en 2012

Intravenous immunoglobulins reverse acute vaso-occlusive crises in sickle cell mice through rapid inhibition of neutrophil adhesion.

artículo científico publicado en 2007

Leukocyte podosomes sense their way through the endothelium

scientific article published on 01 June 2007

Lineage-Biased Hematopoietic Stem Cells Are Regulated by Distinct Niches

artículo científico publicado en 2018

Local Adrenergic Nerves Regulate Diurnal Leukocyte Adhesion: Impact In Sickle Cell Disease

artículo científico publicado en 2011

Loss of Adrenergic Nerves in the Bone Marrow Microenvironment Drives an Aging HSC Niche Phenotype

scholarly article

MAEA is an E3 ubiquitin ligase promoting autophagy and maintenance of haematopoietic stem cells

artículo científico publicado en 2021

Macrophage Erythroblast Attacher (MAEA), but Not VCAM1, Is Required for the Bone Marrow Erythroblastic Niche

scholarly article

Macrophages, not neutrophils, infiltrate skeletal muscle in mice deficient in P/E selectins after mechanical reloading

artículo científico publicado en 2003

Maea expressed by macrophages, but not erythroblasts, maintains postnatal murine bone marrow erythroblastic islands

scientific article published on 23 January 2019

Making sense of hematopoietic stem cell niches

artículo científico publicado en 2015

Megakaryocytes Regulate Hematopoietic Stem Cell Quiescence Via PF4 Secretion

artículo científico publicado en 2013

Megakaryocytes regulate hematopoietic stem cell quiescence through CXCL4 secretion.

artículo científico publicado en 2014

Mesenchymal stem cell: keystone of the hematopoietic stem cell niche and a stepping-stone for regenerative medicine

artículo científico publicado en 2013

Mobilized hematopoietic stem cell yield depends on species-specific circadian timing.

artículo científico publicado en 2008

Muscarinic Receptor Type-1 Regulates Centrally Hematopoietic Stem Cell Mobilization By Granulocyte-Colony Stimulating Factor Via the Hypothalamic-Pituitary Axis

artículo científico publicado en 2015

Nerves in cancer

scientific article published on 23 January 2020

Nestin+ Pericytes In The Fetal Liver Are Necessary To Maintain HSCs

scholarly article

Nestin+NG2+ Cells Form a Reserve Stem Cell Population in the Mouse Prostate

scientific article published on 23 May 2019

Neural Regulation of Bone and Bone Marrow.

artículo científico publicado en 2018

Neural regulation of hematopoiesis, inflammation, and cancer

artículo científico publicado en 2015

Neutrophil Aging, Regulated By Microbiota-Derived Signals, Promotes Sickle Cell Vaso-Occlusion

artículo científico publicado en 2013

Neutrophil ageing is regulated by the microbiome

artículo científico publicado en 2015

Neutrophil microdomains: linking heterocellular interactions with vascular injury

artículo científico publicado en 2010

Neutrophils, platelets, and inflammatory pathways at the nexus of sickle cell disease pathophysiology

artículo científico publicado en 2016

Niche derived netrin-1 regulates hematopoietic stem cell dormancy via its receptor neogenin-1

artículo científico publicado en 2021

Niche heterogeneity in the bone marrow

artículo científico publicado en 2016

Niches for Hematopoietic Stem Cells and Their Progeny.

artículo científico publicado en 2018

No "Kindlin," it's all about HSC balance

artículo científico publicado en 2015

Nociceptive nerves regulate haematopoietic stem cell mobilization

artículo científico publicado en 2020

Nociceptors protect sickle cell disease mice from vaso-occlusive episodes and chronic organ damage

artículo científico publicado en 2021

Norepinephrine reuptake inhibition promotes mobilization in mice: potential impact to rescue low stem cell yields

artículo científico publicado en 2012

Osteoblasts: yes, they can

artículo científico publicado en 2008

Osterix marks distinct waves of primitive and definitive stromal progenitors during bone marrow development.

artículo científico publicado en 2014

PDGFRα and CD51 mark human nestin+ sphere-forming mesenchymal stem cells capable of hematopoietic progenitor cell expansion

artículo científico publicado en 2013

PSGL-1 participates in E-selectin-mediated progenitor homing to bone marrow: evidence for cooperation between E-selectin ligands and alpha4 integrin.

artículo científico publicado en 2003

Physiological contribution of CD44 as a ligand for E-Selectin during inflammatory T-cell recruitment.

artículo científico publicado en 2011

Pretransplant CSF-1 therapy expands recipient macrophages and ameliorates GVHD after allogeneic hematopoietic cell transplantation

artículo científico publicado en 2011

Primary role for adherent leukocytes in sickle cell vascular occlusion: a new paradigm

artículo científico publicado en 2002

Prospective cohort study of the circadian rhythm pattern in allogeneic sibling donors undergoing standard granulocyte colony-stimulating factor mobilization

artículo científico publicado en 2013

Randomized phase 2 trial of Intravenous Gamma Globulin (IVIG) for the treatment of acute vaso-occlusive crisis in patients with sickle cell disease: Lessons learned from the midpoint analysis

scientific article published on 09 June 2020

Rapid mobilization of hematopoietic progenitors by AMD3100 and catecholamines is mediated by CXCR4-dependent SDF-1 release from bone marrow stromal cells

artículo científico publicado en 2011

Regulation of leucocyte homeostasis in the circulation.

artículo científico publicado en 2015

Rhythmic modulation of the hematopoietic niche through neutrophil clearance.

artículo científico publicado en 2013

Roadmap for the Emerging Field of Cancer Neuroscience

scientific article published on 01 April 2020

Seasonal manifestations of sickle cell disease activity

scientific article published on 01 April 2019

Self-renewal of a purified Tie2+ hematopoietic stem cell population relies on mitochondrial clearance.

artículo científico publicado en 2016

Sickle cell disease: old discoveries, new concepts, and future promise

artículo científico publicado en 2007

Sickle cell vaso-occlusion

artículo científico publicado en 2005

Sickle cell vaso-occlusion: multistep and multicellular paradigm

artículo científico publicado en 2002

Sickle cell vasoocclusion: heterotypic, multicellular aggregations driven by leukocyte adhesion

artículo científico publicado en 2004

Signals from the sympathetic nervous system regulate hematopoietic stem cell egress from bone marrow

artículo científico publicado en 2006

Single-dose intravenous gammaglobulin can stabilize neutrophil Mac-1 activation in sickle cell pain crisis

artículo científico publicado en 2015

Small RNAs derived from lncRNA RNase MRP have gene-silencing activity relevant to human cartilage-hair hypoplasia

artículo científico publicado en 2013

Snai2 Maintains Bone Marrow Niche Cells by Repressing Osteopontin Expression

scientific article published on 03 May 2020

Stem cell factor is selectively secreted by arterial endothelial cells in bone marrow.

artículo científico publicado en 2018

Stem cells: Reprogramming finds its niche

artículo científico publicado en 2014

Stimulation of Adrenergic Activity By Desipramine Enhances Hematopoietic Stem and Progenitor Cell Mobilization Along with G-CSF in Multiple Myeloma - a Pilot Study of Safety and Efficacy

scholarly article

Stimulation of adrenergic activity by desipramine enhances hematopoietic stem and progenitor cell mobilization along with G-CSF in multiple myeloma: A pilot study

artículo científico publicado en 2017

T-Regulating Hair Follicle Stem Cells

artículo científico publicado en 2017

Targeting CXCR4, SDF1 and Beta-Adrenergic Receptors In the AML Microenvironment by Novel Antagonist POL6326, G-CSF and Isoproterenol

artículo científico publicado en 2010

Targeting Mac-1-mediated leukocyte-RBC interactions uncouples the benefits for acute vaso-occlusion and chronic organ damage

artículo científico publicado en 2016

Targeting Neutrophil Aging and the Microbiota for the Treatment of Sickle Cell Disease

artículo científico publicado en 2015

Tet-mediated DNA demethylation regulates specification of hematopoietic stem and progenitor cells during mammalian embryogenesis

artículo científico publicado en 2022

The Gut Microbiome Regulates Psychological-Stress-Induced Inflammation

scientific article published on 24 July 2020

The Majority of CD45 Ter119 CD31 Bone Marrow Cell Fraction Is of Hematopoietic Origin and Contains Erythroid and Lymphoid Progenitors

artículo científico publicado en 2018

The bone marrow microenvironment at single-cell resolution

scientific article published on 10 April 2019

The good side of inflammation: Staphylococcus aureus proteins SpA and Sbi contribute to proper abscess formation and wound healing during skin and soft tissue infections

scientific article published on 09 July 2019

The hematopoietic stem cell niche: from embryo to adult.

artículo científico publicado en 2018

The integrin alphaMbeta2 anchors hematopoietic progenitors in the bone marrow during enforced mobilization

artículo científico publicado en 2004

The meaning, the sense and the significance: translating the science of mesenchymal stem cells into medicine

artículo científico publicado en 2013

The secrets of the bone marrow niche: Enigmatic niche brings challenge for HSC expansion

artículo científico publicado en 2012

The vessel wall and its interactions

artículo científico publicado en 2008

This niche is a maze; an amazing niche

artículo científico

Tissue-resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytes

artículo científico publicado en 2013

Trafficking of stem cells.

artículo científico publicado en 2011

Use of beta-blocker types and risk of incident prostate cancer in a multiethnic population

scientific article published on 16 April 2020

Vasculature-associated cells expressing nestin in developing bones encompass early cells in the osteoblast and endothelial lineage

artículo científico publicado en 2014

Vaso-Occlusion-Promoting Neutrophil Mac-1 Integrin Activation in Human Sickle Cell Crises Is Stabilized By a Single Dose of Intravenous Gammaglobulin

scholarly article

Vaso-occlusion in sickle cell disease: pathophysiology and novel targeted therapies

artículo científico publicado en 2013

Vaso-occlusion in sickle cell disease: pathophysiology and novel targeted therapies

artículo científico

Vcam1 Is a "Don't-Eat-Me" Signal on Healthy Hematopoietic and Leukemic Stem Cells

artículo científico publicado en 2016

Very low incidence of <i>Clostridioides difficile</i> infection in pediatric sickle cell disease patients

artículo científico publicado en 2020

When integrins fail to integrate

artículo científico publicado en 2009

Whole bone subcutaneous transplantation as a strategy to study precisely the bone marrow niche

artículo científico publicado en 2022