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Lista de obras de Steven Wiley

A general system for studying protein-protein interactions in Gram-negative bacteria

artículo científico publicado en 2008

A steady state model for analyzing the cellular binding, internalization and degradation of polypeptide ligands

artículo científico publicado el 1 de agosto de 1981

A systems perspective of heterocellular signaling.

artículo científico publicado en 2018

Achieving Molecular Selectivity in Imaging Using Multiphoton Raman Spectroscopy Techniques

artículo científico publicado el 1 de noviembre de 2001

Affinity regulates spatial range of EGF receptor autocrine ligand binding

artículo científico publicado en 2002

Amphiregulin acts as an autocrine growth factor in two human polarizing colon cancer lines that exhibit domain selective EGF receptor mitogenesis.

artículo científico publicado en 1999

An analysis pipeline for the inference of protein-protein interaction networks

artículo científico publicado en 2009

An enzymatic method for radiolabeling vertebrate vitellogenin

artículo científico publicado en 1984

An extensive survey of tyrosine phosphorylation revealing new sites in human mammary epithelial cells

artículo científico publicado en 2009

An integrated model of epidermal growth factor receptor trafficking and signal transduction

artículo científico publicado en 2003

Assay of growth factor stimulation of fluid-phase endocytosis

scientific article published on 01 January 1987

Autocrine HBEGF expression promotes breast cancer intravasation, metastasis and macrophage-independent invasion in vivo

artículo científico publicado en 2013

Autocrine epidermal growth factor signaling stimulates directionally persistent mammary epithelial cell migration

artículo científico publicado el 24 de diciembre de 2001

Autocrine loops with positive feedback enable context-dependent cell signaling

artículo científico publicado en 2002

Basic fibroblast growth factor regulates persistent ERK oscillations in premalignant but not malignant JB6 cells.

artículo científico publicado en 2009

Blazing Signature Filter: a library for fast pairwise similarity comparisons

artículo científico publicado en 2018

Carrier-Assisted Single-Tube Processing Approach for Targeted Proteomics Analysis of Low Numbers of Mammalian Cells

scientific article published on 28 December 2018

Cell surface receptors for signal transduction and ligand transport: a design principles study.

artículo científico publicado en 2007

Changes in translational efficiency is a dominant regulatory mechanism in the environmental response of bacteria.

artículo científico publicado en 2013

Characterization and improvement of RNA-Seq precision in quantitative transcript expression profiling.

artículo científico publicado en 2011

Cholesterol dictates the freedom of EGF receptors and HER2 in the plane of the membrane

artículo científico publicado en 2005

Computational modeling of the EGF-receptor system: a paradigm for systems biology

artículo científico publicado en 2003

Conservation of protein abundance patterns reveals the regulatory architecture of the EGFR-MAPK pathway

artículo científico publicado en 2016

Coregulation of Terpenoid Pathway Genes and Prediction of Isoprene Production in Bacillus subtilis Using Transcriptomics

artículo científico publicado en 2013

Coregulation of epidermal growth factor receptor/human epidermal growth factor receptor 2 (HER2) levels and locations: quantitative analysis of HER2 overexpression effects

artículo científico publicado en 2003

Decoding Signal Processing at the Single-Cell Level

artículo científico publicado en 2017

Differential postendocytotic compartmentation in Xenopus oocytes is mediated by a specifically bound ligand

scientific article published on 01 November 1980

EGF-receptor-mediated mammary epithelial cell migration is driven by sustained ERK signaling from autocrine stimulation

artículo científico publicado en 2007

Effect of epidermal growth factor receptor internalization on regulation of the phospholipase C-gamma1 signaling pathway

artículo científico publicado en 1999

Enabling high-throughput data management for systems biology: the Bioinformatics Resource Manager

artículo científico publicado en 2007

Endocytic Relay as a Potential Means for Enhancing Ligand Transport through Cellular Tissue Matrices: Analysis and Possible Implications for Drug Delivery

artículo científico publicado en 1996

Endocytosis and lysosomal targeting of epidermal growth factor receptors are mediated by distinct sequences independent of the tyrosine kinase domain

artículo científico publicado en 1995

Engineering dynamics of growth factors and other therapeutic ligands

artículo científico publicado en 1996

Engineering epidermal growth factor for enhanced mitogenic potency

artículo científico publicado en 1996

ErbB-2 amplification inhibits down-regulation and induces constitutive activation of both ErbB-2 and epidermal growth factor receptors.

artículo científico publicado en 1999

Escape of autocrine ligands into extracellular medium: experimental test of theoretical model predictions

artículo científico publicado en 1998

FRET measurements between small numbers of molecules identifies subtle changes in receptor interactions

Facile carrier-assisted targeted mass spectrometric approach for proteomic analysis of low numbers of mammalian cells

artículo científico publicado en 2018

Flow-cytometric isolation of human antibodies from a nonimmune Saccharomyces cerevisiae surface display library

artículo científico publicado en 2003

Functional independence of the epidermal growth factor receptor from a domain required for ligand-induced internalization and calcium regulation

artículo científico publicado en 1989

Functional reconstitutional of the human epidermal growth factor receptor system in Xenopus oocytes

artículo científico publicado en 1990

Genomes to Life "Center for Molecular and Cellular Systems": a research program for identification and characterization of protein complexes

artículo científico publicado en 2002

Global modulation of the epidermal growth factor receptor is triggered by occupancy of only a few receptors. Evidence for a binary regulatory system in normal human fibroblasts.

artículo científico publicado en 1989

HER/ErbB receptor interactions and signaling patterns in human mammary epithelial cells

artículo científico publicado en 2009

HER2-Mediated Effects on EGFR Endosomal Sorting: Analysis of Biophysical Mechanisms

artículo científico publicado el 1 de octubre de 2003

High speed method for in situ multispectral image registration.

artículo científico publicado en 2007

How low can you go?

scientific article published on 04 January 2018

Identification of Proteins in Human Cytomegalovirus (HCMV) Particles: the HCMV Proteome

artículo científico publicado en 2004

Identification of proteins in human cytomegalovirus (HCMV) particles: the HCMV proteome

artículo científico publicado en 2004

Improving RNA-Seq Precision with MapAl

artículo científico publicado en 2012

Induced autocrine signaling through the epidermal growth factor receptor contributes to the response of mammary epithelial cells to tumor necrosis factor alpha

artículo científico publicado en 2004

Inference of interactions in cyanobacterial-heterotrophic co-cultures via transcriptome sequencing

artículo científico publicado en 2014

Integrated experimental and model-based analysis reveals the spatial aspects of EGFR activation dynamics

artículo científico publicado en 2012

Integrating Multiple Types of Data for Signaling Research: Challenges and Opportunities

artículo científico publicado el 15 de febrero de 2011

Internalized epidermal growth factor receptors participate in the activation of p21(ras) in fibroblasts

artículo científico publicado en 1999

Investigating the correspondence between transcriptomic and proteomic expression profiles using coupled cluster models

artículo científico publicado en 2008

Ligand accumulation in autocrine cell cultures

artículo científico publicado en 2005

Ligand-induced internalization and increased cell calcium are mediated via distinct structural elements in the carboxyl terminus of the epidermal growth factor receptor.

artículo científico publicado en 1991

Ligand-induced transformation by a noninternalizing epidermal growth factor receptor

artículo científico publicado en 1990

Metalloprotease-mediated ligand release regulates autocrine signaling through the epidermal growth factor receptor

artículo científico publicado en 1999

Modeling the effects of HER/ErbB1-3 coexpression on receptor dimerization and biological response

artículo científico publicado en 2006

Molecular/cell engineering approach to autocrine ligand control of cell function.

artículo científico publicado en 1995

Multiple mechanisms are responsible for transactivation of the epidermal growth factor receptor in mammary epithelial cells.

artículo científico publicado en 2008

Mutational removal of the Thr669 and Ser671 phosphorylation sites alters substrate specificity and ligand-induced internalization of the epidermal growth factor receptor

artículo científico publicado en 1990

Network analysis of epidermal growth factor signaling using integrated genomic, proteomic and phosphorylation data

artículo científico publicado en 2012

New methods for the purification of vertebrate vitellogenin

artículo científico publicado en 1979

News

scientific article published on 01 June 2005

Open questions: the disrupted circuitry of the cancer cell

artículo científico publicado en 2014

Oscillatory dynamics of the extracellular signal-regulated kinase pathway

scientific article published on December 2010

Parsing ERK activation reveals quantitatively equivalent contributions from epidermal growth factor receptor and HER2 in human mammary epithelial cells

artículo científico publicado en 2004

Phosphorylation of the epidermal growth factor receptor at threonine 654 inhibits ligand-induced internalization and down-regulation

artículo científico publicado en 1990

Postendocytic trafficking of epidermal growth factor-receptor complexes is mediated through saturable and specific endosomal interactions.

artículo científico publicado en 1994

Predicting Species-Resolved Macronutrient Acquisition during Succession in a Model Phototrophic Biofilm Using an Integrated 'Omics Approach

artículo científico publicado en 2017

Publisher Correction: Transcriptomic and proteomic signatures of stemness and differentiation in the colon crypt

artículo científico publicado en 2020

Quantitative Assessment of Autocrine Cell Loops

artículo científico publicado el 1 de enero de 1999

Quantitative analysis of HER2-mediated effects on HER2 and epidermal growth factor receptor endocytosis: distribution of homo- and heterodimers depends on relative HER2 levels

artículo científico publicado en 2003

Quantitative analysis of the EGF receptor autocrine system reveals cryptic regulation of cell response by ligand capture

artículo científico publicado en 2001

Quantitative analysis of the endocytic system involved in hormone-induced receptor internalization

artículo científico publicado en 1990

Rapid and sustained nuclear-cytoplasmic ERK oscillations induced by epidermal growth factor

artículo científico publicado en 2009

Ratiometric assay of epidermal growth factor receptor tyrosine kinase activation

scientific article published on 01 January 2000

Real-time quantitative measurement of autocrine ligand binding indicates that autocrine loops are spatially localized

artículo científico publicado en 1998

Receptor downregulation and desensitization enhance the information processing ability of signalling receptors

artículo científico publicado en 2007

Receptor-Driven ERK Pulses Reconfigure MAPK Signaling and Enable Persistence of Drug-Adapted BRAF-Mutant Melanoma Cells

artículo científico publicado en 2020

Receptor-mediated endocytosis in Xenopus oocytes. I. Characterization of the vitellogenin receptor system

scientific article published on 01 March 1987

Receptor-mediated endocytosis in Xenopus oocytes. II. Evidence for two novel mechanisms of hormonal regulation.

artículo científico publicado en 1987

Regulation of postendocytic trafficking of the epidermal growth factor receptor through endosomal retention

artículo científico publicado en 1994

Removal of the membrane-anchoring domain of epidermal growth factor leads to intracrine signaling and disruption of mammary epithelial cell organization

artículo científico publicado en 1998

Role of intrinsic protein tyrosine kinase in function and metabolism of the epidermal growth factor receptor

artículo científico publicado en 1988

Science Signaling Podcast for 12 July 2016: Adaptor proteins limit signaling

artículo científico publicado en 2016

Self-organization of polarized cell signaling via autocrine circuits: computational model analysis

artículo científico publicado en 2004

Sensitive targeted quantification of ERK phosphorylation dynamics and stoichiometry in human cells without affinity enrichment

artículo científico publicado en 2014

Should software hold data hostage?

artículo científico publicado en 2004

Simple protein complex purification and identification method for high-throughput mapping of protein interaction networks

scientific article published on 01 March 2005

Smad signaling dynamics: insights from a parsimonious model

artículo científico publicado en 2008

Spatial range of autocrine signaling: modeling and computational analysis

artículo científico publicado en 2001

Specific factors are required for kinase-dependent endocytosis of insulin receptors

artículo científico publicado en 1994

Statistically inferring protein-protein associations with affinity isolation LC-MS/MS assays.

artículo científico publicado en 2007

Structural aspects of the epidermal growth factor receptor required for transmodulation of erbB-2/neu

artículo científico publicado en 1997

Structure of the EGF receptor transactivation circuit integrates multiple signals with cell context

artículo científico publicado en 2010

Studies on engineered autocrine systems: requirements for ligand release from cells producing an artificial growth factor

artículo científico publicado en 1995

Surfactant-assisted one-pot sample preparation for label-free single-cell proteomics

artículo científico publicado en 2021

Targeted Quantification of Phosphorylation Dynamics in the Context of EGFR-MAPK Pathway.

artículo científico publicado en 2018

The Oocyte as an Endocytic Cell

artículo científico publicado el 1 de enero de 1983

The dynamic expression of the epidermal growth factor receptor and epidermal growth factor ligand family in a differentiating intestinal epithelial cell line

artículo científico publicado en 1999

The enhanced tumorigenic activity of a mutant epidermal growth factor receptor common in human cancers is mediated by threshold levels of constitutive tyrosine phosphorylation and unattenuated signaling

artículo científico publicado en 1997

The heparin-binding domain of HB-EGF mediates localization to sites of cell-cell contact and prevents HB-EGF proteolytic release.

artículo científico publicado en 2010

The mammary epithelial cell secretome and its regulation by signal transduction pathways

artículo científico publicado en 2008

The membrane-anchoring domain of epidermal growth factor receptor ligands dictates their ability to operate in juxtacrine mode

artículo científico publicado en 2005

The role of tyrosine kinase activity in endocytosis, compartmentation, and down-regulation of the epidermal growth factor receptor.

artículo científico publicado en 1991

Trafficking and proteolytic release of epidermal growth factor receptor ligands are modulated by their membrane-anchoring domains

artículo científico publicado en 2000

Trafficking of the ErbB receptors and its influence on signaling

artículo científico publicado en 2003

Transcriptomic and proteomic signatures of stemness and differentiation in the colon crypt

artículo científico publicado en 2020