Lista de obras - Iain Fraser - Dominio Público Uruguay

3-Aminobenzamide Prevents Concanavalin A-Induced Acute Hepatitis by an Anti-inflammatory and Anti-oxidative Mechanism

artículo científico publicado en 2018

A Deep Learning Pipeline for Nucleus Segmentation

artículo científico publicado en 2020

A simple method for automatic tracking of actin filaments in the motility assay.

artículo científico publicado en 1996

A single lentiviral vector platform for microRNA-based conditional RNA interference and coordinated transgene expression

artículo científico publicado en 2006

A small sustained increase in NOD1 abundance promotes ligand-independent inflammatory and oncogene transcriptional responses

scientific article published on 08 December 2020

A versatile approach to multiple gene RNA interference using microRNA-based short hairpin RNAs

artículo científico publicado en 2007

Ablation of the regulatory IE1 protein of murine cytomegalovirus alters in vivo pro-inflammatory TNF-alpha production during acute infection

artículo científico publicado en 2012

Activator of G-Protein Signaling 3-Induced Lysosomal Biogenesis Limits Macrophage Intracellular Bacterial Infection

artículo científico publicado en 2015

Alternative splicing regulates the subcellular localization of A-kinase anchoring protein 18 isoforms

artículo científico publicado en 1999

An interactive web-based application for Comprehensive Analysis of RNAi-screen Data

artículo científico publicado en 2016

Analysis of C5a-mediated chemotaxis by lentiviral delivery of small interfering RNA.

artículo científico publicado en 2003

Anti-Inflammatory Chromatinscape Suggests Alternative Mechanisms of Glucocorticoid Receptor Action

artículo científico publicado en 2017

Assay Development for Image-Based Quantification of Intracellular Bacterial Replication and Analysis of the Innate Immune Response to Infection.

artículo científico publicado en 2015

Burkholderia cenocepacia J2315 escapes to the cytosol and actively subverts autophagy in human macrophages.

artículo científico publicado en 2013

Clostridium difficile toxin B differentially affects GPCR-stimulated Ca2+ responses in macrophages: independent roles for Rho and PLA2.

artículo científico publicado en 2010

Commensal-driven immune zonation of the liver promotes host defence

artículo científico publicado en 2020

Comprehensive RNAi-based screening of human and mouse TLR pathways identifies species-specific preferences in signaling protein use.

artículo científico publicado en 2016

Corrigendum: An interactive web-based application for Comprehensive Analysis of RNAi-screen Data.

artículo científico publicado en 2016

Deciphering signaling outcomes from a system of complex networks.

artículo científico publicado en 2009

Development of a cell system for siRNA screening of pathogen responses in human and mouse macrophages

artículo científico publicado en 2015

Distinct NF-κB and MAPK Activation Thresholds Uncouple Steady-State Microbe Sensing from Anti-pathogen Inflammatory Responses.

artículo científico publicado en 2016

Dual Roles for Ikaros in Regulation of Macrophage Chromatin State and Inflammatory Gene Expression

artículo científico publicado en 2018

Enhanced Functional Genomic Screening Identifies Novel Mediators of Dual Leucine Zipper Kinase-Dependent Injury Signaling in Neurons.

artículo científico publicado en 2017

Genome-wide siRNA screen of genes regulating the LPS-induced NF-κB and TNF-α responses in mouse macrophages

scientific article published on March 2017

Genome-wide siRNA screen of genes regulating the LPS-induced TNF-α response in human macrophages.

artículo científico publicado en 2017

Host gene targets for novel influenza therapies elucidated by high-throughput RNA interference screens

artículo científico publicado en 2012

IFN-mediated negative feedback supports bacteria class-specific macrophage inflammatory responses

artículo científico publicado en 2019

Identification of cAMP-dependent protein kinase holoenzymes in preantral- and preovulatory-follicle-enriched ovaries, and their association with A-kinase-anchoring proteins.

artículo científico publicado en 1999

Immune regulation by glucocorticoids can be linked to cell type-dependent transcriptional responses

scientific article published on 23 January 2019

Inflammatory monocytes regulate pathologic responses to commensals during acute gastrointestinal infection.

artículo científico publicado en 2013

Lipopolysaccharide-induced NF-κB nuclear translocation is primarily dependent on MyD88, but TNFα expression requires TRIF and MyD88

artículo científico publicado en 2017

Localization of phospholipid-binding sites of caldesmon

artículo científico publicado en 1994

Mass Spectrometry-based Structural Analysis and Systems Immunoproteomics Strategies for Deciphering the Host Response to Endotoxin

article

Measurement of NF-κB Activation in TLR-Activated Macrophages.

artículo científico publicado en 2018

Molecular characterisation and stage-specific expression of proliferating cell nuclear antigen (PCNA) from the malarial parasite, Plasmodium falciparum.

artículo científico publicado en 1993

Multi-Omics Strategies Uncover Host-Pathogen Interactions

artículo científico publicado en 2019

Navigating the network: signaling cross-talk in hematopoietic cells.

artículo científico publicado en 2009

Navigating the signalling network in mouse cardiac myocytes

artículo científico publicado en 2002

Overview of the Alliance for Cellular Signaling

artículo científico publicado en 2002

Proteome and Secretome Analysis Reveals Differential Post-transcriptional Regulation of Toll-like Receptor Responses

artículo científico publicado en 2017

Signaling and cross-talk by C5a and UDP in macrophages selectively use PLCbeta3 to regulate intracellular free calcium

artículo científico publicado en 2008

Silencing the expression of multiple Gbeta-subunits eliminates signaling mediated by all four families of G proteins.

artículo científico publicado en 2005

Structure-activity studies of the regulatory interaction of the 10 kilodalton C-terminal fragment of caldesmon with actin and the effect of mutation of caldesmon residues 691-696.

artículo científico publicado en 1998

Suppression of LPS-induced TNF-alpha production in macrophages by cAMP is mediated by PKA-AKAP95-p105

scientific journal article

Switching of the relative dominance between feedback mechanisms in lipopolysaccharide-induced NF-κB signaling

artículo científico publicado en 2014

Synergistic Ca2+ responses by G{alpha}i- and G{alpha}q-coupled G-protein-coupled receptors require a single PLC{beta} isoform that is sensitive to both G{beta}{gamma} and G{alpha}q.

artículo científico publicado en 2010

Systematic Investigation of Multi-TLR Sensing Identifies Regulators of Sustained Gene Activation in Macrophages

artículo científico publicado en 2017

Systems biology in immunology: a computational modeling perspective.

artículo científico publicado en 2011

The alliance for cellular signaling plasmid collection: a flexible resource for protein localization studies and signaling pathway analysis

artículo científico publicado en 2006

The cAMP Pathway Amplifies Early MyD88-Dependent and Type I Interferon-Independent LPS-Induced Interleukin-10 Expression in Mouse Macrophages

scientific article published on 17 April 2019

The dynamic ADP-ribosylome, phosphoproteome, and interactome in LPS-activated macrophages

artículo científico publicado en 2020

The inhibitory complex of smooth muscle caldesmon with actin and tropomyosin involves three interacting segments of the C-terminal domain 4

scientific article published on 01 May 1997

The use of RNA interference to analyze protein phosphatase function in mammalian cells

artículo científico publicado en 2007

Type I IFNs facilitate innate immune control of the opportunistic bacteria Burkholderia cenocepacia in the macrophage cytosol

artículo científico publicado en 2021

Use of a cAMP BRET sensor to characterize a novel regulation of cAMP by the sphingosine 1-phosphate/G13 pathway

artículo científico publicado en 2007

Variability in G-protein-coupled signaling studied with microfluidic devices.

artículo científico publicado en 2010

A novel lipid-anchored A-kinase Anchoring Protein facilitates cAMP-responsive membrane events ⬇️

artículo científico publicado el 15 de abril de 1998

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

artículo científico publicado en 2016

Lista de obras de Iain Fraser

3-Aminobenzamide Prevents Concanavalin A-Induced Acute Hepatitis by an Anti-inflammatory and Anti-oxidative Mechanism

A Deep Learning Pipeline for Nucleus Segmentation

A simple method for automatic tracking of actin filaments in the motility assay.

A single lentiviral vector platform for microRNA-based conditional RNA interference and coordinated transgene expression

A small sustained increase in NOD1 abundance promotes ligand-independent inflammatory and oncogene transcriptional responses

A versatile approach to multiple gene RNA interference using microRNA-based short hairpin RNAs

Ablation of the regulatory IE1 protein of murine cytomegalovirus alters in vivo pro-inflammatory TNF-alpha production during acute infection

Activator of G-Protein Signaling 3-Induced Lysosomal Biogenesis Limits Macrophage Intracellular Bacterial Infection

Alternative splicing regulates the subcellular localization of A-kinase anchoring protein 18 isoforms

An interactive web-based application for Comprehensive Analysis of RNAi-screen Data

Analysis of C5a-mediated chemotaxis by lentiviral delivery of small interfering RNA.

Anti-Inflammatory Chromatinscape Suggests Alternative Mechanisms of Glucocorticoid Receptor Action

Assay Development for Image-Based Quantification of Intracellular Bacterial Replication and Analysis of the Innate Immune Response to Infection.

Burkholderia cenocepacia J2315 escapes to the cytosol and actively subverts autophagy in human macrophages.

Clostridium difficile toxin B differentially affects GPCR-stimulated Ca2+ responses in macrophages: independent roles for Rho and PLA2.

Commensal-driven immune zonation of the liver promotes host defence

Comprehensive RNAi-based screening of human and mouse TLR pathways identifies species-specific preferences in signaling protein use.

Corrigendum: An interactive web-based application for Comprehensive Analysis of RNAi-screen Data.

Deciphering signaling outcomes from a system of complex networks.

Development of a cell system for siRNA screening of pathogen responses in human and mouse macrophages

Distinct NF-κB and MAPK Activation Thresholds Uncouple Steady-State Microbe Sensing from Anti-pathogen Inflammatory Responses.

Dual Roles for Ikaros in Regulation of Macrophage Chromatin State and Inflammatory Gene Expression

Enhanced Functional Genomic Screening Identifies Novel Mediators of Dual Leucine Zipper Kinase-Dependent Injury Signaling in Neurons.

Genome-wide siRNA screen of genes regulating the LPS-induced NF-κB and TNF-α responses in mouse macrophages

Genome-wide siRNA screen of genes regulating the LPS-induced TNF-α response in human macrophages.

Host gene targets for novel influenza therapies elucidated by high-throughput RNA interference screens

IFN-mediated negative feedback supports bacteria class-specific macrophage inflammatory responses

Identification of cAMP-dependent protein kinase holoenzymes in preantral- and preovulatory-follicle-enriched ovaries, and their association with A-kinase-anchoring proteins.

Immune regulation by glucocorticoids can be linked to cell type-dependent transcriptional responses

Inflammatory monocytes regulate pathologic responses to commensals during acute gastrointestinal infection.

Lipopolysaccharide-induced NF-κB nuclear translocation is primarily dependent on MyD88, but TNFα expression requires TRIF and MyD88

Localization of phospholipid-binding sites of caldesmon

Mass Spectrometry-based Structural Analysis and Systems Immunoproteomics Strategies for Deciphering the Host Response to Endotoxin

Measurement of NF-κB Activation in TLR-Activated Macrophages.

Molecular characterisation and stage-specific expression of proliferating cell nuclear antigen (PCNA) from the malarial parasite, Plasmodium falciparum.

Multi-Omics Strategies Uncover Host-Pathogen Interactions

Navigating the network: signaling cross-talk in hematopoietic cells.

Navigating the signalling network in mouse cardiac myocytes

Overview of the Alliance for Cellular Signaling

Proteome and Secretome Analysis Reveals Differential Post-transcriptional Regulation of Toll-like Receptor Responses

Signaling and cross-talk by C5a and UDP in macrophages selectively use PLCbeta3 to regulate intracellular free calcium

Silencing the expression of multiple Gbeta-subunits eliminates signaling mediated by all four families of G proteins.

Structure-activity studies of the regulatory interaction of the 10 kilodalton C-terminal fragment of caldesmon with actin and the effect of mutation of caldesmon residues 691-696.

Suppression of LPS-induced TNF-alpha production in macrophages by cAMP is mediated by PKA-AKAP95-p105

Switching of the relative dominance between feedback mechanisms in lipopolysaccharide-induced NF-κB signaling

Synergistic Ca2+ responses by G{alpha}i- and G{alpha}q-coupled G-protein-coupled receptors require a single PLC{beta} isoform that is sensitive to both G{beta}{gamma} and G{alpha}q.

Systematic Investigation of Multi-TLR Sensing Identifies Regulators of Sustained Gene Activation in Macrophages

Systems biology in immunology: a computational modeling perspective.

The alliance for cellular signaling plasmid collection: a flexible resource for protein localization studies and signaling pathway analysis

The cAMP Pathway Amplifies Early MyD88-Dependent and Type I Interferon-Independent LPS-Induced Interleukin-10 Expression in Mouse Macrophages

The dynamic ADP-ribosylome, phosphoproteome, and interactome in LPS-activated macrophages

The inhibitory complex of smooth muscle caldesmon with actin and tropomyosin involves three interacting segments of the C-terminal domain 4

The use of RNA interference to analyze protein phosphatase function in mammalian cells

Type I IFNs facilitate innate immune control of the opportunistic bacteria Burkholderia cenocepacia in the macrophage cytosol

Use of a cAMP BRET sensor to characterize a novel regulation of cAMP by the sphingosine 1-phosphate/G13 pathway

Variability in G-protein-coupled signaling studied with microfluidic devices.

A novel lipid-anchored A-kinase Anchoring Protein facilitates cAMP-responsive membrane events ⬇️

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)