Lista de obras - Isabel Mérida - Dominio Público Uruguay

A Blk-p190RhoGAP signaling module downstream of activated Gα13 functionally opposes CXCL12-stimulated RhoA activation and cell invasion

artículo científico publicado en 2014

A molecular code for endosomal recycling of phosphorylated cargos by the SNX27-retromer complex

artículo científico publicado en 2016

A new role of diacylglycerol kinase alpha on the secretion of lethal exosomes bearing Fas ligand during activation-induced cell death of T lymphocytes

artículo científico publicado en 2006

A phospho-oligosaccharide mimics the effect of insulin to inhibit isoproterenol-dependent phosphorylation of phospholipid methyltransferase in isolated adipocytes

artículo científico publicado en 1987

A role for novel lipid interactions in the dynamic recruitment of SNX27 to the T-cell immune synapse

artículo científico publicado en 2014

Activation of partially purified rat liver lipid methyltransferase by phosphorylation

artículo científico publicado en 1984

Analysis of the inhibitor binding to the nucleoside site of phosphorylase

scientific article published in 1984

Beta2-chimaerin provides a diacylglycerol-dependent mechanism for regulation of adhesion and chemotaxis of T cells

artículo científico publicado en 2006

Cell surface CD28 levels define four CD4+ T cell subsets: abnormal expression in rheumatoid arthritis.

artículo científico

Changes in the balance between mitogenic and antimitogenic lipid second messengers during proliferation, cell arrest, and apoptosis in T-lymphocytes.

artículo científico publicado en 2000

Conformational changes required in the human growth hormone receptor for growth hormone signaling.

artículo científico publicado en 1997

Diacylglycerol Kinase Malfunction in Human Disease and the Search for Specific Inhibitors

scientific article published on 22 June 2019

Diacylglycerol Kinase ζ Limits Cytokine-dependent Expansion of CD8+ T Cells with Broad Antitumor Capacity.

artículo científico publicado en 2017

Diacylglycerol is required for the formation of COPI vesicles in the Golgi-to-ER transport pathway.

artículo científico publicado en 2007

Diacylglycerol kinase alpha activity promotes survival of CD4+ 8+ double positive cells during thymocyte development.

artículo científico publicado en 2002

Diacylglycerol kinase alpha regulates the secretion of lethal exosomes bearing Fas ligand during activation-induced cell death of T lymphocytes

artículo científico publicado en 2005

Diacylglycerol kinase alpha, from negative modulation of T cell activation to control of cancer progression.

artículo científico publicado en 2009

Diacylglycerol kinase control of protein kinase C

scientific article published on 18 April 2019

Diacylglycerol kinase α inactivation is an integral component of the costimulatory pathway that amplifies TCR signals.

artículo científico publicado en 2018

Diacylglycerol kinase α promotes 3D cancer cell growth and limits drug sensitivity through functional interaction with Src.

artículo científico publicado en 2014

Diacylglycerol kinase α regulates the formation and polarisation of mature multivesicular bodies involved in the secretion of Fas ligand-containing exosomes in T lymphocytes

artículo científico publicado en 2011

Diacylglycerol kinase ζ controls diacylglycerol metabolism at the immunological synapse.

artículo científico publicado en 2011

Diacylglycerol kinase ζ limits IL-2-dependent control of PD-1 expression in tumor-infiltrating T lymphocytes

artículo científico publicado en 2020

Diacylglycerol kinase ζ limits the polarized recruitment of diacylglycerol-enriched organelles to the immune synapse in T cells.

artículo científico publicado en 2016

Diacylglycerol kinase ζ promotes actin cytoskeleton remodeling and mechanical forces at the B cell immune synapse

scientific article published on 14 April 2020

Diacylglycerol kinase ζ: at the crossroads of lipid signaling and protein complex organization.

artículo científico publicado en 2011

Diacylglycerol kinase-ζ regulates mTORC1 and lipogenic metabolism in cancer cells through SREBP-1

artículo científico publicado en 2015

Diacylglycerol kinases in cancer.

artículo científico publicado en 2016

Diacylglycerol kinases: at the hub of cell signalling

artículo científico publicado en 2008

Diacylglycerol metabolism attenuates T-cell receptor signaling and alters thymocyte differentiation

artículo científico publicado en 2013

Diacylglycerol, when simplicity becomes complex.

artículo científico publicado en 2006

Diacylglycerol-dependent binding recruits PKCtheta and RasGRP1 C1 domains to specific subcellular localizations in living T lymphocytes.

artículo científico publicado en 2004

Different phosphorylated forms of an insulin-sensitive glycosylphosphatidylinositol from rat hepatocytes

scientific article published on 01 August 1988

Differential effect of rapamycin and cyclosporin A in proliferation in a murine T cell line expressing either intermediate or high affinity receptor for IL-2.

artículo científico publicado en 1995

Dual role of ceramide in the control of apoptosis following IL-2 withdrawal.

artículo científico publicado en 1998

Dynamics of diacylglycerol kinase zeta translocation in living T-cells. Study of the structural domain requirements for translocation and activity

artículo científico publicado en 2002

Editorial: Diacylglycerol Kinase Signalling.

artículo científico publicado en 2017

Effects of alloxan on S-adenosylmethionine metabolism in the rat liver

artículo científico publicado en 1986

Enterotoxin septic shock protection and deficient T helper 2 cytokine production in growth hormone transgenic mice

scientific article published on 01 October 1996

Essential function for the GTPase TC21 in homeostatic antigen receptor signaling.

artículo científico publicado en 2009

Evidence for the involvement of diacylglycerol kinase in the activation of hypoxia-inducible transcription factor 1 by low oxygen tension

scientific article published on 02 January 2001

Evidence that protein tyrosine kinase p56-Lck regulates the activity of phosphatidylinositol-3'-kinase in interleukin-2-dependent T-cells

artículo científico publicado en 1993

FoxO-dependent regulation of diacylglycerol kinase α gene expression

artículo científico publicado en 2012

Glucose transport and antilipolysis are differentially regulated by the polar head group of an insulin-sensitive glycophospholipid

artículo científico publicado en 1987

Identification of insulin-like growth factor-binding protein-1 as a potential physiological substrate for human stromelysin-3

artículo científico publicado en 1997

Importance of chroman ring and tyrosine phosphorylation in the subtype-specific translocation and activation of diacylglycerol kinase alpha by D-alpha-tocopherol.

artículo científico publicado en 2005

Inhibition by insulin of glucagon-dependent phospholipid methyltransferase phosphorylation in rat hepatocytes

artículo científico publicado en 1987

Interleukin-2 causes an increase in saturated/monounsaturated phosphatidic acid derived from 1,2-diacylglycerol and 1-O-alkyl-2-acylglycerol

artículo científico publicado en 1999

Interleukin-2 stimulates a late increase in phosphatidic acid production in the absence of phospholipase D activation.

artículo científico publicado en 1998

Intermediate Affinity Interleukin-2 Receptor Mediates Survival via a Phosphatidylinositol 3-Kinase-dependent Pathway

scientific article published in Journal of Biological Chemistry

Involvement of phosphatidylinositol 3-kinase in stromal cell-derived factor-1 alpha-induced lymphocyte polarization and chemotaxis

artículo científico publicado en 1999

Linomide prevents the lethal effect of anti-Fas antibody and reduces Fas-mediated ceramide production in mouse hepatocytes.

artículo científico publicado en 1996

Membrane translocation of protein kinase Ctheta during T lymphocyte activation requires phospholipase C-gamma-generated diacylglycerol

artículo científico publicado en 2003

Modulation by the ratio S-adenosylmethionineS-adenosylhomocysteine of cyclic AMP-dependent phosphorylation of the 50 kDa protein of rat liver phospholipid methyltransferase

artículo científico publicado en 1985

Modulation of the mammalian target of rapamycin pathway by diacylglycerol kinase-produced phosphatidic acid

artículo científico publicado en 2005

Phosphatidic acid generation through interleukin 2 (IL-2)-induced alpha-diacylglycerol kinase activation is an essential step in IL-2-mediated lymphocyte proliferation

artículo científico publicado en 1996

Phosphoinositide binding by the SNX27 FERM domain regulates its localization at the immune synapse of activated T-cells

artículo científico publicado en 2015

Phospholipid methyltransferase phosphorylation by intact hepatocytes: Effect of glucagon

artículo científico publicado en 1985

Predominant contribution of DGKζ over DGKα in the control of PKC/PDK-1-regulated functions in T cells.

artículo científico publicado en 2017

Protein and lipid kinase activation cascades in interleukin-2 receptor signalling.

artículo científico publicado en 1993

Protein kinase D1/2 is involved in the maturation of multivesicular bodies and secretion of exosomes in T and B lymphocytes

artículo científico publicado en 2015

Proteomics identification of sorting nexin 27 as a diacylglycerol kinase zeta-associated protein: new diacylglycerol kinase roles in endocytic recycling

artículo científico publicado en 2007

Protooncogene-encoded protein kinases in interleukin-2 signal transduction.

artículo científico publicado en 1993

Redundant and specialized roles for diacylglycerol kinases α and ζ in the control of T cell functions

artículo científico

Regulation of diacylglycerol kinase alpha by phosphoinositide 3-kinase lipid products

scientific journal article

Regulation of interleukin 2-dependent growth responses by glycosylphosphatidylinositol molecules

artículo científico publicado en 1990

Role of diacylglycerol kinase alpha in the attenuation of receptor signaling

artículo científico publicado en 2001

Role of the diacylglycerol kinase alpha-conserved domains in membrane targeting in intact T cells

artículo científico publicado en 2007

SNX27 links DGKζ to the control of transcriptional and metabolic programs in T lymphocytes

artículo científico publicado en 2017

Shaping up the membrane: diacylglycerol coordinates spatial orientation of signaling.

artículo científico publicado en 2011

Sorting nexin 27 interactome in T-lymphocytes identifies zona occludens-2 dynamic redistribution at the immune synapse

artículo científico publicado en 2017

T cell activation in vivo targets diacylglycerol kinase alpha to the membrane: a novel mechanism for Ras attenuation

artículo científico publicado en 2003

T cell receptor-dependent tyrosine phosphorylation of beta2-chimaerin modulates its Rac-GAP function in T cells

artículo científico publicado en 2009

The identification of phosphatidylinositol 3,5-bisphosphate in T-lymphocytes and its regulation by interleukin-2.

artículo científico publicado en 1999

The membrane proximal segment of the IL-2 receptor beta-chain acidic region is essential for IL2-dependent protein tyrosine kinase activation

artículo científico publicado en 1994

The role of diacylglycerol kinase activation and phosphatidate accumulation in interleukin-2-dependent lymphocyte proliferation.

artículo científico publicado en 1993

The serine-rich cytoplasmic domain of the interleukin-2 receptor beta chain is essential for interleukin-2-dependent tyrosine protein kinase and phosphatidylinositol-3-kinase activation.

artículo científico publicado en 1993

Transcriptional Activity of FOXO Transcription Factors Measured by Luciferase Assays

artículo científico publicado en 2019

Translocation dynamics of sorting nexin 27 in activated T cells ⬇️

artículo científico publicado el 8 de febrero de 2011

Vasopressin-stimulated phosphorylation of rat liver phospholipid methyltransferase in isolated hepatocytes

artículo científico publicado en 1986

c-Abl Tyrosine Kinase Regulates Serum-induced Nuclear Export of Diacylglycerol Kinase α by Phosphorylation at Tyr-218 ⬇️

artículo científico publicado el 23 de diciembre de 2011

Lista de obras de Isabel Mérida

A Blk-p190RhoGAP signaling module downstream of activated Gα13 functionally opposes CXCL12-stimulated RhoA activation and cell invasion

A molecular code for endosomal recycling of phosphorylated cargos by the SNX27-retromer complex

A new role of diacylglycerol kinase alpha on the secretion of lethal exosomes bearing Fas ligand during activation-induced cell death of T lymphocytes

A phospho-oligosaccharide mimics the effect of insulin to inhibit isoproterenol-dependent phosphorylation of phospholipid methyltransferase in isolated adipocytes

A role for novel lipid interactions in the dynamic recruitment of SNX27 to the T-cell immune synapse

Activation of partially purified rat liver lipid methyltransferase by phosphorylation

Analysis of the inhibitor binding to the nucleoside site of phosphorylase

Beta2-chimaerin provides a diacylglycerol-dependent mechanism for regulation of adhesion and chemotaxis of T cells

Cell surface CD28 levels define four CD4+ T cell subsets: abnormal expression in rheumatoid arthritis.

Changes in the balance between mitogenic and antimitogenic lipid second messengers during proliferation, cell arrest, and apoptosis in T-lymphocytes.

Conformational changes required in the human growth hormone receptor for growth hormone signaling.

Diacylglycerol Kinase Malfunction in Human Disease and the Search for Specific Inhibitors

Diacylglycerol Kinase ζ Limits Cytokine-dependent Expansion of CD8+ T Cells with Broad Antitumor Capacity.

Diacylglycerol is required for the formation of COPI vesicles in the Golgi-to-ER transport pathway.

Diacylglycerol kinase alpha activity promotes survival of CD4+ 8+ double positive cells during thymocyte development.

Diacylglycerol kinase alpha regulates the secretion of lethal exosomes bearing Fas ligand during activation-induced cell death of T lymphocytes

Diacylglycerol kinase alpha, from negative modulation of T cell activation to control of cancer progression.

Diacylglycerol kinase control of protein kinase C

Diacylglycerol kinase α inactivation is an integral component of the costimulatory pathway that amplifies TCR signals.

Diacylglycerol kinase α promotes 3D cancer cell growth and limits drug sensitivity through functional interaction with Src.

Diacylglycerol kinase α regulates the formation and polarisation of mature multivesicular bodies involved in the secretion of Fas ligand-containing exosomes in T lymphocytes

Diacylglycerol kinase ζ controls diacylglycerol metabolism at the immunological synapse.

Diacylglycerol kinase ζ limits IL-2-dependent control of PD-1 expression in tumor-infiltrating T lymphocytes

Diacylglycerol kinase ζ limits the polarized recruitment of diacylglycerol-enriched organelles to the immune synapse in T cells.

Diacylglycerol kinase ζ promotes actin cytoskeleton remodeling and mechanical forces at the B cell immune synapse

Diacylglycerol kinase ζ: at the crossroads of lipid signaling and protein complex organization.

Diacylglycerol kinase-ζ regulates mTORC1 and lipogenic metabolism in cancer cells through SREBP-1

Diacylglycerol kinases in cancer.

Diacylglycerol kinases: at the hub of cell signalling

Diacylglycerol metabolism attenuates T-cell receptor signaling and alters thymocyte differentiation

Diacylglycerol, when simplicity becomes complex.

Diacylglycerol-dependent binding recruits PKCtheta and RasGRP1 C1 domains to specific subcellular localizations in living T lymphocytes.

Different phosphorylated forms of an insulin-sensitive glycosylphosphatidylinositol from rat hepatocytes

Differential effect of rapamycin and cyclosporin A in proliferation in a murine T cell line expressing either intermediate or high affinity receptor for IL-2.

Dual role of ceramide in the control of apoptosis following IL-2 withdrawal.

Dynamics of diacylglycerol kinase zeta translocation in living T-cells. Study of the structural domain requirements for translocation and activity

Editorial: Diacylglycerol Kinase Signalling.

Effects of alloxan on S-adenosylmethionine metabolism in the rat liver

Enterotoxin septic shock protection and deficient T helper 2 cytokine production in growth hormone transgenic mice

Essential function for the GTPase TC21 in homeostatic antigen receptor signaling.

Evidence for the involvement of diacylglycerol kinase in the activation of hypoxia-inducible transcription factor 1 by low oxygen tension

Evidence that protein tyrosine kinase p56-Lck regulates the activity of phosphatidylinositol-3'-kinase in interleukin-2-dependent T-cells

FoxO-dependent regulation of diacylglycerol kinase α gene expression

Glucose transport and antilipolysis are differentially regulated by the polar head group of an insulin-sensitive glycophospholipid

Identification of insulin-like growth factor-binding protein-1 as a potential physiological substrate for human stromelysin-3

Importance of chroman ring and tyrosine phosphorylation in the subtype-specific translocation and activation of diacylglycerol kinase alpha by D-alpha-tocopherol.

Inhibition by insulin of glucagon-dependent phospholipid methyltransferase phosphorylation in rat hepatocytes

Interleukin-2 causes an increase in saturated/monounsaturated phosphatidic acid derived from 1,2-diacylglycerol and 1-O-alkyl-2-acylglycerol

Interleukin-2 stimulates a late increase in phosphatidic acid production in the absence of phospholipase D activation.

Intermediate Affinity Interleukin-2 Receptor Mediates Survival via a Phosphatidylinositol 3-Kinase-dependent Pathway

Involvement of phosphatidylinositol 3-kinase in stromal cell-derived factor-1 alpha-induced lymphocyte polarization and chemotaxis

Linomide prevents the lethal effect of anti-Fas antibody and reduces Fas-mediated ceramide production in mouse hepatocytes.

Membrane translocation of protein kinase Ctheta during T lymphocyte activation requires phospholipase C-gamma-generated diacylglycerol

Modulation by the ratio S-adenosylmethionineS-adenosylhomocysteine of cyclic AMP-dependent phosphorylation of the 50 kDa protein of rat liver phospholipid methyltransferase

Modulation of the mammalian target of rapamycin pathway by diacylglycerol kinase-produced phosphatidic acid

Phosphatidic acid generation through interleukin 2 (IL-2)-induced alpha-diacylglycerol kinase activation is an essential step in IL-2-mediated lymphocyte proliferation

Phosphoinositide binding by the SNX27 FERM domain regulates its localization at the immune synapse of activated T-cells

Phospholipid methyltransferase phosphorylation by intact hepatocytes: Effect of glucagon

Predominant contribution of DGKζ over DGKα in the control of PKC/PDK-1-regulated functions in T cells.

Protein and lipid kinase activation cascades in interleukin-2 receptor signalling.

Protein kinase D1/2 is involved in the maturation of multivesicular bodies and secretion of exosomes in T and B lymphocytes

Proteomics identification of sorting nexin 27 as a diacylglycerol kinase zeta-associated protein: new diacylglycerol kinase roles in endocytic recycling

Protooncogene-encoded protein kinases in interleukin-2 signal transduction.

Redundant and specialized roles for diacylglycerol kinases α and ζ in the control of T cell functions

Regulation of diacylglycerol kinase alpha by phosphoinositide 3-kinase lipid products

Regulation of interleukin 2-dependent growth responses by glycosylphosphatidylinositol molecules

Role of diacylglycerol kinase alpha in the attenuation of receptor signaling

Role of the diacylglycerol kinase alpha-conserved domains in membrane targeting in intact T cells

SNX27 links DGKζ to the control of transcriptional and metabolic programs in T lymphocytes

Shaping up the membrane: diacylglycerol coordinates spatial orientation of signaling.

Sorting nexin 27 interactome in T-lymphocytes identifies zona occludens-2 dynamic redistribution at the immune synapse

T cell activation in vivo targets diacylglycerol kinase alpha to the membrane: a novel mechanism for Ras attenuation

T cell receptor-dependent tyrosine phosphorylation of beta2-chimaerin modulates its Rac-GAP function in T cells

The identification of phosphatidylinositol 3,5-bisphosphate in T-lymphocytes and its regulation by interleukin-2.

The membrane proximal segment of the IL-2 receptor beta-chain acidic region is essential for IL2-dependent protein tyrosine kinase activation

The role of diacylglycerol kinase activation and phosphatidate accumulation in interleukin-2-dependent lymphocyte proliferation.

The serine-rich cytoplasmic domain of the interleukin-2 receptor beta chain is essential for interleukin-2-dependent tyrosine protein kinase and phosphatidylinositol-3-kinase activation.

Transcriptional Activity of FOXO Transcription Factors Measured by Luciferase Assays

Translocation dynamics of sorting nexin 27 in activated T cells ⬇️