Lista de obras -

35th Annual Meeting of the European Association for the Study of Diabetes

artículo científico

A 9-kDa matricellular SPARC fragment released by cathepsin D exhibits pro-tumor activity in the triple-negative breast cancer microenvironment

artículo científico publicado en 2021

A constitutive nitric oxide synthase modulates insulin secretion in the INS-1 cell line

artículo científico publicado en 2001

A neuronal isoform of nitric oxide synthase expressed in pancreatic beta-cells controls insulin secretion

artículo científico publicado en 2001

A peptide mimetic of an anti-CD4 monoclonal antibody by rational design

scientific article published on 01 July 2003

A recombinant human monoclonal anti-R7V antibody as a potential therapy for HIV infected patients in failure of HAART.

artículo científico publicado en 2007

A recycling anti-transferrin receptor-1 monoclonal antibody as an efficient therapy for erythroleukemia through target up-regulation and antibody-dependent cytotoxic effector functions

artículo científico publicado en 2019

Amplification of the secretory IgA response to Toxoplasma gondii using cholera toxin

artículo científico publicado en 1991

An auristatin-based antibody-drug conjugate targeting HER3 enhances the radiation response in pancreatic cancer

scientific article published on 01 April 2019

Anti-HER2 vaccines: new prospects for breast cancer therapy

artículo científico publicado en 2010

Anti-HER3 domain 1 and 3 antibodies reduce tumor growth by hindering HER2/HER3 dimerization and AKT-induced MDM2, XIAP, and FoxO1 phosphorylation.

artículo científico publicado en 2013

Anti-Müllerian hormone (AMH) autocrine signaling promotes survival and proliferation of ovarian cancer cells

artículo científico publicado en 2021

Anti-digoxin scFv fragments expressed in bacteria and in insect cells have different antigen binding properties.

artículo científico publicado en 1998

Antibody responses to Toxoplasma gondii in sera, intestinal secretions, and milk from orally infected mice and characterization of target antigens

artículo científico publicado en 1990

Application of the Spot method to the identification of peptides and amino acids from the antibody paratope that contribute to antigen binding

artículo científico publicado en 2002

Biasing HER4 Tyrosine Kinase Signaling with Antibodies: Induction of Cell Death by Antibody-Dependent 4ICD Trafficking

artículo científico publicado en 2020

Biological activities on T lymphocytes of a baculovirus-expressed chimeric recombinant IgG1 antibody with specificity for the CDR3-like loop on the D1 domain of the CD4 molecule.

artículo científico publicado en 2006

CD4 ligation excludes the Carma1-Bcl10-MALT1 complex from GM1-positive membrane rafts in CD3/CD28 activated T cells

artículo científico publicado en 2011

Cellular and humoral recognition of Toxoplasma gondii P30 antigen and its cleavage fragments

artículo científico publicado en 1992

Directed mutagenesis in region 713-720 of human thyroperoxidase assigns 713KFPED717 residues as being involved in the B domain of the discontinuous immunodominant region recognized by human autoantibodies

artículo científico publicado en 2004

Efficient CD4 binding and immunosuppressive properties of the 13B8.2 monoclonal antibody are displayed by its CDR-H1-derived peptide CB1.

artículo científico publicado en 2001

Efficient amplification and direct sequencing of mouse variable regions from any immunoglobulin gene family

artículo científico publicado en 1999

Epitopic analysis of the Toxoplasma gondii major surface antigen SAG1

artículo científico publicado en 1994

Evidence for two discontinuous regions on the thyrotropin receptor involved in the binding of the monoclonal antibody 34A.

artículo científico publicado en 2004

Examination of HER3 targeting in cancer using monoclonal antibodies

artículo científico publicado en 2015

HER3 as biomarker and therapeutic target in pancreatic cancer: new insights in pertuzumab therapy in preclinical models

artículo científico publicado en 2014

ITCH-dependent proteasomal degradation of c-FLIP induced by the anti-HER3 antibody 9F7-F11 promotes DR5/caspase 8-mediated apoptosis of tumor cells

artículo científico publicado en 2019

Immunological characterization of a 17-kDa antigen from Cryptosporidium parvum recognized early by mucosal IgA antibodies.

artículo científico publicado en 1992

Immunotherapy of triple-negative breast cancer with cathepsin D-targeting antibodies

artículo científico publicado en 2019

In pancreatic carcinoma, dual EGFR/HER2 targeting with cetuximab/trastuzumab is more effective than treatment with trastuzumab/erlotinib or lapatinib alone: implication of receptors' down-regulation and dimers' disruption

artículo científico publicado en 2012

In vitro antitumoral activity of baculovirus-expressed chimeric recombinant anti-CD4 antibody 13B8.2 on T-cell lymphomas

artículo científico publicado en 2007

Local and systemic cellular immunity following oral infection of mice with Toxoplasma gondii cysts

scientific article published on 01 January 1992

Localization of the discontinuous immunodominant region recognized by human anti-thyroperoxidase autoantibodies in autoimmune thyroid diseases

artículo científico publicado en 2002

Localized Irradiation of Cell Membrane by Auger Electrons Is Cytotoxic Through Oxidative Stress-Mediated Nontargeted Effects

artículo científico publicado en 2016

Mapping of B epitopes in GRA4, a dense granule antigen of Toxoplasma gondii and protection studies using recombinant proteins administered by the oral route

artículo científico publicado en 1998

Mapping the paratope of anti-CD4 recombinant Fab 13B8.2 by combining parallel peptide synthesis and site-directed mutagenesis

artículo científico publicado en 2003

Molecular cloning of GRA4, a Toxoplasma gondii dense granule protein, recognized by mucosal IgA antibodies

artículo científico publicado en 1992

Monoclonal antibody 667 recognizes the variable region A motif of the ecotropic retrovirus CasBrE envelope glycoprotein and inhibits Env binding to the viral receptor

artículo científico publicado en 2003

Mucosal and systemic cellular immune responses induced by Toxoplasma gondii antigens in cyst orally infected mice

artículo científico publicado en 1993

Mucosal immune response in toxoplasmosis

artículo científico publicado en 1993

Mucosal vaccination against toxoplasmosis

scientific article published on 01 January 1995

Neuregulin 1 Allosterically Enhances the Antitumor Effects of the Noncompeting Anti-HER3 Antibody 9F7-F11 by Increasing Its Binding to HER3.

artículo científico publicado en 2017

Oral immunization with Toxoplasma gondii antigens in association with cholera toxin induces enhanced protective and cell-mediated immunity in C57BL/6 mice.

artículo científico publicado en 1993

PIN-bodies: a new class of antibody-like proteins with CD4 specificity derived from the protein inhibitor of neuronal nitric oxide synthase.

artículo científico publicado en 2006

Peritoneal macrophages from C57BL/6 mice orally immunized with Toxoplasma gondii antigens in association with cholera toxin possess an enhanced ability to inhibit parasite multiplication

artículo científico publicado en 1995

Pertinence of kappa and lambda recombinant antibodies directed against thyroid peroxidase in thyroid autoimmune disease.

artículo científico publicado en 2001

Preclinical validation of AXL receptor as a target for antibody-based pancreatic cancer immunotherapy

artículo científico publicado en 2013

Production and characterization of monoclonal antibodies against human thyroglobulin

artículo científico publicado en 1985

Production and partial characterization of anti-Candida monoclonal antibodies

scientific article published on 01 March 1986

Protection against Chlamydia psittaci in mice conferred by Lyt-2+ T cells

artículo científico publicado en 1992

Protein inhibitor of neuronal nitric oxide synthase (PIN) is a new regulator of glucose-induced insulin secretion

scientific journal article

Recombinant anti-CD4 antibody 13B8.2 blocks membrane-proximal events by excluding the Zap70 molecule and downstream targets SLP-76, PLC gamma 1, and Vav-1 from the CD4-segregated Brij 98 detergent-resistant raft domains

scientific article published on 01 July 2007

Synthetic peptides derived from the variable regions of an anti-CD4 monoclonal antibody bind to CD4 and inhibit HIV-1 promoter activation in virus-infected cells

artículo científico publicado en 1999

Targeting the NRG1/HER3 pathway in tumor cells and cancer-associated fibroblasts with an anti-neuregulin 1 antibody inhibits tumor growth in pre-clinical models of pancreatic cancer

artículo científico publicado en 2018

The anti-HER3 (ErbB3) therapeutic antibody 9F7-F11 induces HER3 ubiquitination and degradation in tumors through JNK1/2- dependent ITCH/AIP4 activation

artículo científico publicado en 2016

The anti-tumor efficacy of 3C23K, a glyco-engineered humanized anti-MISRII antibody, in an ovarian cancer model is mainly mediated by engagement of immune effector cells

artículo científico publicado en 2017

The chimeric mouse-human anti-CD4 Fab 13B8.2 expressed in baculovirus inhibits both antigen presentation and HIV-1 promoter activation

artículo científico publicado en 2001

The human Müllerian inhibiting substance type II receptor as immunotherapy target for ovarian cancer. Validation using the mAb 12G4.

artículo científico publicado en 2014

The human anti-thyroid peroxidase autoantibody repertoire in Graves' and Hashimoto's autoimmune thyroid diseases

artículo científico publicado en 2002

The lipid-modulating effects of a CD4-specific recombinant antibody correlate with ZAP-70 segregation outside membrane rafts

artículo científico publicado en 2010

Thyroid peroxidase autoantibodies obtained from random single chain FV libraries contain the same heavy/light chain combinations as occur in vivo.

artículo científico publicado en 2001

Time-resolved fluorescence resonance energy transfer (TR-FRET) to analyze the disruption of EGFR/HER2 dimers: a new method to evaluate the efficiency of targeted therapy using monoclonal antibodies

artículo científico publicado en 2011

Toxoplasma gondii oral infection induces specific cytotoxic CD8 alpha/beta+ Thy-1+ gut intraepithelial lymphocytes, lytic for parasite-infected enterocytes.

artículo científico publicado en 1994

Vaccination with human anti-trastuzumab anti-idiotype scFv reverses HER2 immunological tolerance and induces tumor immunity in MMTV.f.huHER2(Fo5) mice. ⬇️

artículo científico publicado en 2011

[Mimicking polyclonal immune response in therapy: from combination of two monoclonal antibodies to oligoclonal antibody-based mixtures]

scientific article published on 01 December 2019

[The HER3/ERBB3 receptor: the dark side of the ERBB planet].

artículo científico publicado en 2015

Lista de obras de

35th Annual Meeting of the European Association for the Study of Diabetes

A 9-kDa matricellular SPARC fragment released by cathepsin D exhibits pro-tumor activity in the triple-negative breast cancer microenvironment

A constitutive nitric oxide synthase modulates insulin secretion in the INS-1 cell line

A neuronal isoform of nitric oxide synthase expressed in pancreatic beta-cells controls insulin secretion

A peptide mimetic of an anti-CD4 monoclonal antibody by rational design

A recombinant human monoclonal anti-R7V antibody as a potential therapy for HIV infected patients in failure of HAART.

A recycling anti-transferrin receptor-1 monoclonal antibody as an efficient therapy for erythroleukemia through target up-regulation and antibody-dependent cytotoxic effector functions

Amplification of the secretory IgA response to Toxoplasma gondii using cholera toxin

An auristatin-based antibody-drug conjugate targeting HER3 enhances the radiation response in pancreatic cancer

Anti-HER2 vaccines: new prospects for breast cancer therapy

Anti-HER3 domain 1 and 3 antibodies reduce tumor growth by hindering HER2/HER3 dimerization and AKT-induced MDM2, XIAP, and FoxO1 phosphorylation.

Anti-Müllerian hormone (AMH) autocrine signaling promotes survival and proliferation of ovarian cancer cells

Anti-digoxin scFv fragments expressed in bacteria and in insect cells have different antigen binding properties.

Antibody responses to Toxoplasma gondii in sera, intestinal secretions, and milk from orally infected mice and characterization of target antigens

Application of the Spot method to the identification of peptides and amino acids from the antibody paratope that contribute to antigen binding

Biasing HER4 Tyrosine Kinase Signaling with Antibodies: Induction of Cell Death by Antibody-Dependent 4ICD Trafficking

Biological activities on T lymphocytes of a baculovirus-expressed chimeric recombinant IgG1 antibody with specificity for the CDR3-like loop on the D1 domain of the CD4 molecule.

CD4 ligation excludes the Carma1-Bcl10-MALT1 complex from GM1-positive membrane rafts in CD3/CD28 activated T cells

Cellular and humoral recognition of Toxoplasma gondii P30 antigen and its cleavage fragments

Directed mutagenesis in region 713-720 of human thyroperoxidase assigns 713KFPED717 residues as being involved in the B domain of the discontinuous immunodominant region recognized by human autoantibodies

Efficient CD4 binding and immunosuppressive properties of the 13B8.2 monoclonal antibody are displayed by its CDR-H1-derived peptide CB1.

Efficient amplification and direct sequencing of mouse variable regions from any immunoglobulin gene family

Epitopic analysis of the Toxoplasma gondii major surface antigen SAG1

Evidence for two discontinuous regions on the thyrotropin receptor involved in the binding of the monoclonal antibody 34A.

Examination of HER3 targeting in cancer using monoclonal antibodies

HER3 as biomarker and therapeutic target in pancreatic cancer: new insights in pertuzumab therapy in preclinical models

ITCH-dependent proteasomal degradation of c-FLIP induced by the anti-HER3 antibody 9F7-F11 promotes DR5/caspase 8-mediated apoptosis of tumor cells

Immunological characterization of a 17-kDa antigen from Cryptosporidium parvum recognized early by mucosal IgA antibodies.

Immunotherapy of triple-negative breast cancer with cathepsin D-targeting antibodies

In pancreatic carcinoma, dual EGFR/HER2 targeting with cetuximab/trastuzumab is more effective than treatment with trastuzumab/erlotinib or lapatinib alone: implication of receptors' down-regulation and dimers' disruption

In vitro antitumoral activity of baculovirus-expressed chimeric recombinant anti-CD4 antibody 13B8.2 on T-cell lymphomas

Local and systemic cellular immunity following oral infection of mice with Toxoplasma gondii cysts

Localization of the discontinuous immunodominant region recognized by human anti-thyroperoxidase autoantibodies in autoimmune thyroid diseases

Localized Irradiation of Cell Membrane by Auger Electrons Is Cytotoxic Through Oxidative Stress-Mediated Nontargeted Effects

Mapping of B epitopes in GRA4, a dense granule antigen of Toxoplasma gondii and protection studies using recombinant proteins administered by the oral route

Mapping the paratope of anti-CD4 recombinant Fab 13B8.2 by combining parallel peptide synthesis and site-directed mutagenesis

Molecular cloning of GRA4, a Toxoplasma gondii dense granule protein, recognized by mucosal IgA antibodies

Monoclonal antibody 667 recognizes the variable region A motif of the ecotropic retrovirus CasBrE envelope glycoprotein and inhibits Env binding to the viral receptor

Mucosal and systemic cellular immune responses induced by Toxoplasma gondii antigens in cyst orally infected mice

Mucosal immune response in toxoplasmosis

Mucosal vaccination against toxoplasmosis

Neuregulin 1 Allosterically Enhances the Antitumor Effects of the Noncompeting Anti-HER3 Antibody 9F7-F11 by Increasing Its Binding to HER3.

Oral immunization with Toxoplasma gondii antigens in association with cholera toxin induces enhanced protective and cell-mediated immunity in C57BL/6 mice.

PIN-bodies: a new class of antibody-like proteins with CD4 specificity derived from the protein inhibitor of neuronal nitric oxide synthase.

Peritoneal macrophages from C57BL/6 mice orally immunized with Toxoplasma gondii antigens in association with cholera toxin possess an enhanced ability to inhibit parasite multiplication

Pertinence of kappa and lambda recombinant antibodies directed against thyroid peroxidase in thyroid autoimmune disease.

Preclinical validation of AXL receptor as a target for antibody-based pancreatic cancer immunotherapy

Production and characterization of monoclonal antibodies against human thyroglobulin

Production and partial characterization of anti-Candida monoclonal antibodies

Protection against Chlamydia psittaci in mice conferred by Lyt-2+ T cells

Protein inhibitor of neuronal nitric oxide synthase (PIN) is a new regulator of glucose-induced insulin secretion

Recombinant anti-CD4 antibody 13B8.2 blocks membrane-proximal events by excluding the Zap70 molecule and downstream targets SLP-76, PLC gamma 1, and Vav-1 from the CD4-segregated Brij 98 detergent-resistant raft domains

Synthetic peptides derived from the variable regions of an anti-CD4 monoclonal antibody bind to CD4 and inhibit HIV-1 promoter activation in virus-infected cells

Targeting the NRG1/HER3 pathway in tumor cells and cancer-associated fibroblasts with an anti-neuregulin 1 antibody inhibits tumor growth in pre-clinical models of pancreatic cancer

The anti-HER3 (ErbB3) therapeutic antibody 9F7-F11 induces HER3 ubiquitination and degradation in tumors through JNK1/2- dependent ITCH/AIP4 activation

The anti-tumor efficacy of 3C23K, a glyco-engineered humanized anti-MISRII antibody, in an ovarian cancer model is mainly mediated by engagement of immune effector cells

The chimeric mouse-human anti-CD4 Fab 13B8.2 expressed in baculovirus inhibits both antigen presentation and HIV-1 promoter activation

The human Müllerian inhibiting substance type II receptor as immunotherapy target for ovarian cancer. Validation using the mAb 12G4.

The human anti-thyroid peroxidase autoantibody repertoire in Graves' and Hashimoto's autoimmune thyroid diseases

The lipid-modulating effects of a CD4-specific recombinant antibody correlate with ZAP-70 segregation outside membrane rafts

Thyroid peroxidase autoantibodies obtained from random single chain FV libraries contain the same heavy/light chain combinations as occur in vivo.

Time-resolved fluorescence resonance energy transfer (TR-FRET) to analyze the disruption of EGFR/HER2 dimers: a new method to evaluate the efficiency of targeted therapy using monoclonal antibodies

Toxoplasma gondii oral infection induces specific cytotoxic CD8 alpha/beta+ Thy-1+ gut intraepithelial lymphocytes, lytic for parasite-infected enterocytes.

Vaccination with human anti-trastuzumab anti-idiotype scFv reverses HER2 immunological tolerance and induces tumor immunity in MMTV.f.huHER2(Fo5) mice. ⬇️

[Mimicking polyclonal immune response in therapy: from combination of two monoclonal antibodies to oligoclonal antibody-based mixtures]

[The HER3/ERBB3 receptor: the dark side of the ERBB planet].