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Lista de obras de Urmi Dhagat

A dual role for the N-terminal domain of the IL-3 receptor in cell signalling.

artículo científico publicado en 2018

A salicylic acid-based analogue discovered from virtual screening as a potent inhibitor of human 20alpha-hydroxysteroid dehydrogenase.

artículo científico publicado en 2007

Activation of aldo-keto reductase family member 1B14 (AKR1B14) by bile acids: Activation mechanism and bile acid-binding site

artículo científico publicado en 2011

Author Correction: EPO does not promote interaction between the erythropoietin and beta-common receptors

artículo científico publicado en 2019

CSL311, a novel, potent, therapeutic monoclonal antibody for the treatment of diseases mediated by the common β chain of the IL-3, GM-CSF and IL-5 receptors

artículo científico publicado en 2015

Conformational Changes in the GM-CSF Receptor Suggest a Molecular Mechanism for Affinity Conversion and Receptor Signaling

artículo científico publicado en 2016

Crystallization and preliminary X-ray diffraction analysis of the interleukin-3 alpha receptor bound to the Fab fragment of antibody CSL362.

scientific article published on 19 February 2014

Dual mechanism of interleukin-3 receptor blockade by an anti-cancer antibody

artículo científico publicado en 2014

EPO does not promote interaction between the erythropoietin and beta-common receptors

artículo científico publicado en 2018

Factorizing the role of a critical leucine residue in the binding of substrate to human 20alpha-hydroxysteroid dehydrogenase (AKR1C1): molecular modeling and kinetic studies of the Leu308Val mutant enzyme.

artículo científico publicado en 2010

Inhibition of 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21) by aldose reductase inhibitors

artículo científico publicado en 2007

Inhibitors of human 20α-hydroxysteroid dehydrogenase (AKR1C1).

artículo científico publicado en 2010

Molecular determinants for the stereospecific reduction of 3-ketosteroids and reactivity towards all-trans-retinal of a short-chain dehydrogenase/reductase (DHRS4)

artículo científico publicado en 2009

Role of the β Common (βc) Family of Cytokines in Health and Disease

artículo científico publicado en 2017

Signalling by the βc family of cytokines

artículo científico

Structure of the G225P/G226P mutant of mouse 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21) ternary complex: implications for the binding of inhibitor and substrate

artículo científico publicado en 2009

Structure-based optimization and biological evaluation of human 20α-hydroxysteroid dehydrogenase (AKR1C1) salicylic acid-based inhibitors.

artículo científico publicado en 2010

Structure-guided design, synthesis, and evaluation of salicylic acid-based inhibitors targeting a selectivity pocket in the active site of human 20alpha-hydroxysteroid dehydrogenase (AKR1C1).

artículo científico publicado en 2009

Studies on a Tyr residue critical for the binding of coenzyme and substrate in mouse 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21): structure of the Y224D mutant enzyme

artículo científico publicado en 2010

The GM-CSF/IL-3/IL-5 cytokine receptor family: from ligand recognition to initiation of signaling

artículo científico publicado en 2012

The mechanism of GM-CSF inhibition by human GM-CSF auto-antibodies suggests novel therapeutic opportunities

artículo científico publicado en 2018

The βc receptor family - Structural insights and their functional implications

artículo científico

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