Lista de obras - Minos-Timotheos Matsoukas

Citrullination of linear and cyclic altered peptide ligands from myelin basic protein (MBP(87-99)) epitope elicits a Th1 polarized response by T cells isolated from multiple sclerosis patients: implications in triggering disease

artículo científico publicado en 2008

Combined Computational and Structural Approach into Understanding the Role of Peptide Binding and Activation of Melanocortin Receptor 4

artículo científico publicado en 2020

Computational approaches in target identification and drug discovery

artículo científico publicado en 2016

Conformational analysis of aliskiren, a potent renin inhibitor, using high-resolution nuclear magnetic resonance and molecular dynamics simulations.

artículo científico publicado en 2011

Conformational analysis of the ΜΒΡ83-99 (Phe91) and ΜΒΡ83-99 (Tyr91) peptide analogues and study of their interactions with the HLA-DR2 and human TCR receptors by using molecular dynamics

scientific article published on 06 September 2011

Conformational studies of immunodominant myelin basic protein 1–11 analogues using NMR and molecular modeling

Current understanding of the structure and function of family B GPCRs to design novel drugs

scientific article published on 01 March 2018

Cyclic MOG35-55 ameliorates clinical and neuropathological features of experimental autoimmune encephalomyelitis

artículo científico

Cyclic citrullinated MBP87-99 peptide stimulates T cell responses: Implications in triggering disease

artículo científico publicado en 2016

Cytochrome P450 CYP1 metabolism of hydroxylated flavones and flavonols: Selective bioactivation of luteolin in breast cancer cells.

artículo científico publicado en 2017

Design and Synthesis of a Cyclic Double Mutant Peptide (cyclo(87−99)[A91,A96]MBP87−99) Induces Altered Responses in Mice after Conjugation to Mannan: Implications in the Immunotherapy of Multiple Sclerosis

article

Design of Linear and Cyclic Mutant Analogues of Dirucotide Peptide (MBP) against Multiple Sclerosis: Conformational and Binding Studies to MHC Class II

Dynamic properties of the growth hormone releasing hormone receptor (GHRHR) and molecular determinants of GHRH binding

artículo científico publicado en 2017

Exploring new scaffolds for angiotensin II receptor antagonism

artículo científico publicado en 2016

Family B G protein-coupled receptors and their ligands: From structure to function.

artículo científico publicado en 2017

Functional elements of the gastric inhibitory polypeptide receptor: Comparison between secretin- and rhodopsin-like G protein-coupled receptors

artículo científico publicado en 2015

GPCRmd uncovers the dynamics of the 3D-GPCRome

scientific article published on 13 July 2020

How far have we come with contextual data integration in drug discovery?

scientific article published on 30 July 2018

Identification of compounds that bind the centriolar protein SAS-6 and inhibit its oligomerisation

artículo científico publicado en 2020

Identification of small-molecule inhibitors of calcineurin-NFATc signaling that mimic the PxIxIT motif of calcineurin binding partners.

artículo científico publicado en 2015

Lead Identification Through the Synergistic Action of Biomolecular NMR and In Silico Methodologies

artículo científico publicado en 2018

Ligand binding determinants for angiotensin II type 1 receptor from computer simulations

artículo científico publicado en 2013

Ligand-Triggered Structural Changes in the M2 Muscarinic Acetylcholine Receptor

artículo científico publicado en 2018

Lysophosphatidic acid produced by Autotaxin acts as an allosteric modulator of its catalytic efficiency

Nitrate Esters of Heteroaromatic Compounds as Candida albicans CYP51 Enzyme Inhibitors.

artículo científico publicado en 2017

Nonconventional glucagon and GLP-1 receptor agonist and antagonist interplay at the GLP-1 receptor revealed in high-throughput FRET assays for cAMP

scientific article published on 08 January 2019

Novel Hit Compounds as Putative Antifungals: The Case of Aspergillus fumigatus

scientific article published on 25 October 2019

Pharmacometabolomics Informs Quantitative Radiomics for Glioblastoma Diagnostic Innovation.

artículo científico publicado en 2017

Publisher Correction: GPCRmd uncovers the dynamics of the 3D-GPCRome

scientific article published on 23 July 2020

Review cyclic peptides on a merry-go-round; towards drug design

artículo científico

Round and round we go: cyclic peptides in disease

artículo científico publicado en 2006

Structural elucidation of Leuprolide and its analogues in solution: insight into their bioactive conformation

artículo científico publicado en 2010

Structural-functional analysis of the third transmembrane domain of the corticotropin-releasing factor type 1 receptor: role in activation and allosteric antagonism

artículo científico publicado en 2014

The size matters? A computational tool to design bivalent ligands

scientific article published on 01 November 2018

Understanding Corticotropin Releasing Factor receptor (CRFR) Activation Using Structural Models

artículo científico publicado en 2017

Lista de obras de Minos-Timotheos Matsoukas

Citrullination of linear and cyclic altered peptide ligands from myelin basic protein (MBP(87-99)) epitope elicits a Th1 polarized response by T cells isolated from multiple sclerosis patients: implications in triggering disease

Combined Computational and Structural Approach into Understanding the Role of Peptide Binding and Activation of Melanocortin Receptor 4

Computational approaches in target identification and drug discovery

Conformational analysis of aliskiren, a potent renin inhibitor, using high-resolution nuclear magnetic resonance and molecular dynamics simulations.

Conformational analysis of the ΜΒΡ83-99 (Phe91) and ΜΒΡ83-99 (Tyr91) peptide analogues and study of their interactions with the HLA-DR2 and human TCR receptors by using molecular dynamics

Conformational studies of immunodominant myelin basic protein 1–11 analogues using NMR and molecular modeling

Current understanding of the structure and function of family B GPCRs to design novel drugs

Cyclic MOG35-55 ameliorates clinical and neuropathological features of experimental autoimmune encephalomyelitis

Cyclic citrullinated MBP87-99 peptide stimulates T cell responses: Implications in triggering disease

Cytochrome P450 CYP1 metabolism of hydroxylated flavones and flavonols: Selective bioactivation of luteolin in breast cancer cells.

Design and Synthesis of a Cyclic Double Mutant Peptide (cyclo(87−99)[A91,A96]MBP87−99) Induces Altered Responses in Mice after Conjugation to Mannan: Implications in the Immunotherapy of Multiple Sclerosis

Design of Linear and Cyclic Mutant Analogues of Dirucotide Peptide (MBP) against Multiple Sclerosis: Conformational and Binding Studies to MHC Class II

Dynamic properties of the growth hormone releasing hormone receptor (GHRHR) and molecular determinants of GHRH binding

Exploring new scaffolds for angiotensin II receptor antagonism

Family B G protein-coupled receptors and their ligands: From structure to function.

Functional elements of the gastric inhibitory polypeptide receptor: Comparison between secretin- and rhodopsin-like G protein-coupled receptors

GPCRmd uncovers the dynamics of the 3D-GPCRome

How far have we come with contextual data integration in drug discovery?

Identification of compounds that bind the centriolar protein SAS-6 and inhibit its oligomerisation

Identification of small-molecule inhibitors of calcineurin-NFATc signaling that mimic the PxIxIT motif of calcineurin binding partners.

Lead Identification Through the Synergistic Action of Biomolecular NMR and In Silico Methodologies

Ligand binding determinants for angiotensin II type 1 receptor from computer simulations

Ligand-Triggered Structural Changes in the M2 Muscarinic Acetylcholine Receptor

Lysophosphatidic acid produced by Autotaxin acts as an allosteric modulator of its catalytic efficiency

Nitrate Esters of Heteroaromatic Compounds as Candida albicans CYP51 Enzyme Inhibitors.

Nonconventional glucagon and GLP-1 receptor agonist and antagonist interplay at the GLP-1 receptor revealed in high-throughput FRET assays for cAMP

Novel Hit Compounds as Putative Antifungals: The Case of Aspergillus fumigatus

Pharmacometabolomics Informs Quantitative Radiomics for Glioblastoma Diagnostic Innovation.

Publisher Correction: GPCRmd uncovers the dynamics of the 3D-GPCRome

Review cyclic peptides on a merry-go-round; towards drug design

Round and round we go: cyclic peptides in disease

Structural elucidation of Leuprolide and its analogues in solution: insight into their bioactive conformation

Structural-functional analysis of the third transmembrane domain of the corticotropin-releasing factor type 1 receptor: role in activation and allosteric antagonism

The size matters? A computational tool to design bivalent ligands

Understanding Corticotropin Releasing Factor receptor (CRFR) Activation Using Structural Models