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Lista de obras de Christoph Spiess

A temperature-dependent switch from chaperone to protease in a widely conserved heat shock protein.

artículo científico publicado en 1999

Alternative molecular formats and therapeutic applications for bispecific antibodies

artículo científico publicado en 2015

Antitumor efficacy of a bispecific antibody that targets HER2 and activates T cells

artículo científico publicado en 2014

Avidity-based binding to HER2 results in selective killing of HER2-overexpressing cells by anti-HER2/CD3

artículo científico publicado en 2018

Bispecific antibodies with natural architecture produced by co-culture of bacteria expressing two distinct half-antibodies ⬇️

artículo científico publicado el 7 de julio de 2013

Characterization of Chain Pairing Variants of Bispecific IgG Expressed in a Single Host Cell by High-Resolution Native and Denaturing Mass Spectrometry.

artículo científico publicado en 2016

Design and Pharmacokinetic Characterization of Novel Antibody Formats for Ocular Therapeutics

artículo científico publicado en 2015

Determinants of Translocation and Folding of TreF, a Trehalase ofEscherichia coli

artículo científico publicado en 2000

Development of a Human IgG4 Bispecific Antibody for Dual Targeting of Interleukin-4 (IL-4) and Interleukin-13 (IL-13) Cytokines ⬇️

artículo científico publicado el 23 de julio de 2013

Effector-attenuating Substitutions That Maintain Antibody Stability and Reduce Toxicity in Mice

artículo científico publicado en 2017

Efficient production of bispecific IgG of different isotypes and species of origin in single mammalian cells.

artículo científico publicado en 2016

Evading pre-existing anti-hinge antibody binding by hinge engineering.

artículo científico publicado en 2016

High-resolution glycosylation site-engineering method identifies MICA epitope critical for shedding inhibition activity of anti-MICA antibodies

scientific article published on 22 November 2018

High-throughput antibody screening from complex matrices using intact protein electrospray mass spectrometry

artículo científico publicado en 2020

Identification of the TRiC/CCT substrate binding sites uncovers the function of subunit diversity in eukaryotic chaperonins

artículo científico publicado en 2006

Mechanism of the eukaryotic chaperonin: protein folding in the chamber of secrets.

artículo científico publicado en 2004

Optimizing antibody expression by using the naturally occurring framework diversity in a live bacterial antibody display system

artículo científico publicado en 2015

Precise quantification of mixtures of bispecific IgG produced in single host cells by liquid chromatography-Orbitrap high-resolution mass spectrometry.

artículo científico publicado en 2016

Prediction of methionine oxidation risk in monoclonal antibodies using a machine learning method

scientific article published on 25 September 2018

Production, characterization, and in vivo half-life extension of polymeric IgA molecules in mice

artículo científico publicado en 2019

Single cell-produced and in vitro-assembled anti-FcRH5/CD3 T-cell dependent bispecific antibodies have similar in vitro and in vivo properties

artículo científico publicado en 2018

Susceptibility of Antibody CDR Residues to Chemical Modifications Can Be Revealed Prior to Antibody Humanization and Aid in the Lead Selection Process

artículo científico publicado en 2018

Sustained Brown Fat Stimulation and Insulin Sensitization by a Humanized Bispecific Antibody Agonist for Fibroblast Growth Factor Receptor 1/βKlotho Complex

artículo científico publicado en 2015

Tethered-variable CL bispecific IgG: an antibody platform for rapid bispecific antibody screening.

artículo científico publicado en 2017

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