Lista de obras - John Streicher - Dominio Público Uruguay

(-)-Hardwickiic Acid and Hautriwaic Acid Induce Antinociception via Blockade of Tetrodotoxin-Sensitive Voltage-Dependent Sodium Channels

scientific article published on 20 December 2018

17-Cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6β-(4'-pyridylcarboxamido)morphinan (NAP) Modulating the Mu Opioid Receptor in a Biased Fashion

artículo científico publicado en 2015

A Kappa Opioid Receptor Agonist Blocks Bone Cancer Pain Without Altering Bone Loss, Tumor Size, or Cancer Cell Proliferation in a Mouse Model of Cancer-Induced Bone Pain.

artículo científico publicado en 2018

A Novel Mu-Delta Opioid Agonist Demonstrates Enhanced Efficacy With Reduced Tolerance and Dependence in Mouse Neuropathic Pain Models

artículo científico publicado en 2019

Antagonist for the Kappa Opioid Receptor ⬇️

artículo científico publicado el 18 de noviembre de 2011

Behavioral and cellular pharmacology characterization of 17-cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6α-(isoquinoline-3'-carboxamido)morphinan (NAQ) as a mu opioid receptor selective ligand

artículo científico publicado en 2014

Cannabis sativa terpenes are cannabimimetic and selectively enhance cannabinoid activity

artículo científico publicado en 2021

Clozapine acts as an agonist at serotonin 2A receptors to counter MK-801-induced behaviors through a βarrestin2-independent activation of Akt

artículo científico publicado en 2014

Compensatory hypertrophy induced by ventricular cardiomyocyte-specific COX-2 expression in mice

artículo científico publicado en 2010

Comprehensive molecular pharmacology screening reveals potential new receptor interactions for clinically relevant opioids

scientific article published on 06 June 2019

Development of functionally selective, small molecule agonists at kappa opioid receptors

artículo científico publicado en 2013

Differential regulation of proteasome function in isoproterenol-induced cardiac hypertrophy

artículo científico publicado en 2010

Differential signaling properties at the kappa opioid receptor of 12-epi-salvinorin A and its analogues

artículo científico publicado en 2011

Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy.

artículo científico publicado en 2012

Functional selectivity of 6'-guanidinonaltrindole (6'-GNTI) at κ-opioid receptors in striatal neurons

artículo científico publicado en 2013

Heat-shock protein 90 (Hsp90) promotes opioid-induced anti-nociception by an ERK mitogen-activated protein kinase (MAPK) mechanism in mouse brain.

artículo científico publicado en 2017

Inhibition of Hsp90 in the spinal cord enhances the antinociceptive effects of morphine by activating an ERK-RSK pathway

scientific article published on 05 May 2020

Kappa opioid receptor antagonists: A possible new class of therapeutics for migraine prevention

artículo científico publicado en 2017

MAPK-activated protein kinase-2 in cardiac hypertrophy and cyclooxygenase-2 regulation in heart

artículo científico publicado en 2010

Novel Molecular Strategies and Targets for Opioid Drug Discovery for the Treatment of Chronic Pain

artículo científico publicado en 2017

Potency enhancement of the κ-opioid receptor antagonist probe ML140 through sulfonamide constraint utilizing a tetrahydroisoquinoline motif

artículo científico publicado en 2014

Potent, Efficacious, and Stable Cyclic Opioid Peptides with Long Lasting Antinociceptive Effect after Peripheral Administration

scientific article published on 27 December 2019

Preserved heart function and maintained response to cardiac stresses in a genetic model of cardiomyocyte-targeted deficiency of cyclooxygenase-2.

artículo científico publicado en 2010

Proteasome-dependent degradation of cytochromes P450 2E1 and 2B1 expressed in tetracycline-regulated HeLa cells.

artículo científico publicado en 2004

Reversal of Peripheral Neuropathic Pain by the Small-Molecule Natural Product Physalin F via Block of CaV2.3 (R-Type) and CaV2.2 (N-Type) Voltage-Gated Calcium Channels

scientific article published on 18 April 2019

Serotonin-related gene expression in female monkeys with individual sensitivity to stress.

artículo científico publicado en 2005

Structure-Activity Relationships of [des-Arg7]Dynorphin A Analogues at the κ Opioid Receptor

artículo científico publicado en 2016

Synergistic interaction of the cannabinoid and death receptor systems - a potential target for future cancer therapies?

artículo científico publicado en 2017

Synthesis and Evaluation of a Novel Bivalent Selective Antagonist for the Mu-Delta Opioid Receptor Heterodimer that Reduces Morphine Withdrawal in Mice

artículo científico publicado en 2018

Synthesis and Pharmacology of a Novel μ-δ Opioid Receptor Heteromer-Selective Agonist Based on the Carfentanyl Template

artículo científico publicado en 2020

Synthesis of conolidine, a potent non-opioid analgesic for tonic and persistent pain.

artículo científico publicado en 2011

The Role of Heat Shock Proteins in Regulating Receptor Signal Transduction

scientific article published on 22 January 2019

The endomorphin-1/2 and dynorphin-B peptides display biased agonism at the mu opioid receptor

artículo científico publicado en 2020

The mixed-action delta/mu opioid agonist MMP-2200 does not produce conditioned place preference but does maintain drug self-administration in rats, and induces in vitro markers of tolerance and dependence

artículo científico publicado en 2015

Lista de obras de John Streicher

(-)-Hardwickiic Acid and Hautriwaic Acid Induce Antinociception via Blockade of Tetrodotoxin-Sensitive Voltage-Dependent Sodium Channels

17-Cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6β-(4'-pyridylcarboxamido)morphinan (NAP) Modulating the Mu Opioid Receptor in a Biased Fashion

A Kappa Opioid Receptor Agonist Blocks Bone Cancer Pain Without Altering Bone Loss, Tumor Size, or Cancer Cell Proliferation in a Mouse Model of Cancer-Induced Bone Pain.

A Novel Mu-Delta Opioid Agonist Demonstrates Enhanced Efficacy With Reduced Tolerance and Dependence in Mouse Neuropathic Pain Models

Antagonist for the Kappa Opioid Receptor ⬇️

Behavioral and cellular pharmacology characterization of 17-cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6α-(isoquinoline-3'-carboxamido)morphinan (NAQ) as a mu opioid receptor selective ligand

Cannabis sativa terpenes are cannabimimetic and selectively enhance cannabinoid activity

Clozapine acts as an agonist at serotonin 2A receptors to counter MK-801-induced behaviors through a βarrestin2-independent activation of Akt

Compensatory hypertrophy induced by ventricular cardiomyocyte-specific COX-2 expression in mice

Comprehensive molecular pharmacology screening reveals potential new receptor interactions for clinically relevant opioids

Development of functionally selective, small molecule agonists at kappa opioid receptors

Differential regulation of proteasome function in isoproterenol-induced cardiac hypertrophy

Differential signaling properties at the kappa opioid receptor of 12-epi-salvinorin A and its analogues

Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy.

Functional selectivity of 6'-guanidinonaltrindole (6'-GNTI) at κ-opioid receptors in striatal neurons

Heat-shock protein 90 (Hsp90) promotes opioid-induced anti-nociception by an ERK mitogen-activated protein kinase (MAPK) mechanism in mouse brain.

Inhibition of Hsp90 in the spinal cord enhances the antinociceptive effects of morphine by activating an ERK-RSK pathway

Kappa opioid receptor antagonists: A possible new class of therapeutics for migraine prevention

MAPK-activated protein kinase-2 in cardiac hypertrophy and cyclooxygenase-2 regulation in heart

Novel Molecular Strategies and Targets for Opioid Drug Discovery for the Treatment of Chronic Pain

Potency enhancement of the κ-opioid receptor antagonist probe ML140 through sulfonamide constraint utilizing a tetrahydroisoquinoline motif

Potent, Efficacious, and Stable Cyclic Opioid Peptides with Long Lasting Antinociceptive Effect after Peripheral Administration

Preserved heart function and maintained response to cardiac stresses in a genetic model of cardiomyocyte-targeted deficiency of cyclooxygenase-2.

Proteasome-dependent degradation of cytochromes P450 2E1 and 2B1 expressed in tetracycline-regulated HeLa cells.

Reversal of Peripheral Neuropathic Pain by the Small-Molecule Natural Product Physalin F via Block of CaV2.3 (R-Type) and CaV2.2 (N-Type) Voltage-Gated Calcium Channels

Serotonin-related gene expression in female monkeys with individual sensitivity to stress.

Structure-Activity Relationships of [des-Arg7]Dynorphin A Analogues at the κ Opioid Receptor

Synergistic interaction of the cannabinoid and death receptor systems - a potential target for future cancer therapies?

Synthesis and Evaluation of a Novel Bivalent Selective Antagonist for the Mu-Delta Opioid Receptor Heterodimer that Reduces Morphine Withdrawal in Mice

Synthesis and Pharmacology of a Novel μ-δ Opioid Receptor Heteromer-Selective Agonist Based on the Carfentanyl Template

Synthesis of conolidine, a potent non-opioid analgesic for tonic and persistent pain.

The Role of Heat Shock Proteins in Regulating Receptor Signal Transduction

The endomorphin-1/2 and dynorphin-B peptides display biased agonism at the mu opioid receptor

The mixed-action delta/mu opioid agonist MMP-2200 does not produce conditioned place preference but does maintain drug self-administration in rats, and induces in vitro markers of tolerance and dependence