Lista de obras - Raghavendra Mirmira - Dominio Público Uruguay

1,25-Dihydroxyvitamin D3 enhances glucose-stimulated insulin secretion in mouse and human islets: a role for transcriptional regulation of voltage-gated calcium channels by the vitamin D receptor

scientific article published on 30 July 2018

12-lipoxygenase promotes obesity-induced oxidative stress in pancreatic islets

artículo científico publicado en 2014

A Versatile, Portable Intravital Microscopy Platform for Studying Beta-cell Biology In Vivo

artículo científico publicado en 2019

A zebrafish tailfin injury assay protocol for quantifying immune cell migration and infiltration

artículo científico publicado en 2022

Abnormalities in proinsulin processing in islets from individuals with longstanding T1D

scientific article published on 09 August 2019

Amelioration of type 1 diabetes following treatment of non-obese diabetic mice with INGAP and lisofylline.

artículo científico publicado en 2012

An In Vivo Zebrafish Model for Interrogating ROS-Mediated Pancreatic β-Cell Injury, Response, and Prevention.

artículo científico publicado en 2018

Analysis of serum Hsp90 as a potential biomarker of β cell autoimmunity in type 1 diabetes

artículo científico publicado en 2019

Biomarkers of islet beta cell stress and death in type 1 diabetes

Biomarkers of β-Cell Stress and Death in Type 1 Diabetes

artículo científico publicado en 2016

Cellular metabolism constrains innate immune responses in early human ontogeny

artículo científico publicado en 2018

Chronic high fat feeding restricts islet mRNA translation initiation independently of ER stress via DNA damage and p53 activation

artículo científico publicado en 2017

Circulating unmethylated CHTOP and INS DNA fragments provide evidence of possible islet cell death in youth with obesity and diabetes

artículo científico publicado en 2020

Deletion of 12/15-lipoxygenase alters macrophage and islet function in NOD-Alox15(null) mice, leading to protection against type 1 diabetes development

artículo científico publicado en 2013

Deoxyhypusine synthase haploinsufficiency attenuates acute cytokine signaling

artículo científico publicado en 2011

Detection of islet β-cell death in vivo by multiplex PCR analysis of differentially methylated DNA.

artículo científico publicado en 2013

Divergent compensatory responses to high-fat diet between C57BL6/J and C57BLKS/J inbred mouse strains

artículo científico publicado en 2013

Elevated unmethylated and methylated insulin DNA are unique markers of A+β+ ketosis prone diabetes

artículo científico publicado en 2017

Elevations in Circulating Methylated and Unmethylated Preproinsulin DNA in New-Onset Type 1 Diabetes

artículo científico publicado en 2015

Elevations in the Fasting Serum Proinsulin-to-C-Peptide Ratio Precede the Onset of Type 1 Diabetes

artículo científico publicado en 2016

Hypoglycemia in a Patient With a Polyhormonal Pancreatic Neuroendocrine Tumor With Evidence of Endocrine Progenitors.

artículo científico publicado en 2018

Hypusinated eIF5A is expressed in the pancreas and spleen of individuals with type 1 and type 2 diabetes

scientific article published on 24 March 2020

Hypusine biosynthesis in β cells links polyamine metabolism to facultative cellular proliferation to maintain glucose homeostasis

artículo científico publicado en 2019

Immune reconstitution in ART treated, but not untreated HIV infection, is associated with abnormal beta cell function.

artículo científico publicado en 2018

Inhibition of 12/15-Lipoxygenase Protects Against β Cell Oxidative Stress and Glycemic Deterioration in Mouse Models of Type 1 Diabetes.

artículo científico

Inhibition of deoxyhypusine synthase enhances islet {beta} cell function and survival in the setting of endoplasmic reticulum stress and type 2 diabetes

artículo científico publicado en 2010

Interleukin-6 Reduces β-Cell Oxidative Stress by Linking Autophagy With the Antioxidant Response

artículo científico publicado en 2018

Islet β-cell endoplasmic reticulum stress precedes the onset of type 1 diabetes in the nonobese diabetic mouse model

artículo científico publicado en 2012

Longitudinal Intravital Imaging of Biosensor-labeled In Situ Islet Beta Cells

Loss of Free Fatty Acid Receptor 2 leads to impaired islet mass and beta cell survival

artículo científico publicado en 2016

Maintenance of Pdx1 mRNA translation in islet β-cells during the unfolded protein response

artículo científico publicado en 2014

Measurement of Differentially Methylated INS DNA Species in Human Serum Samples as a Biomarker of Islet β Cell Death

scientific article published on 21 December 2016

Minireview: 12-Lipoxygenase and Islet β-Cell Dysfunction in Diabetes

artículo científico publicado en 2015

Molecular mechanisms of nonalcoholic fatty liver disease: Potential role for 12-lipoxygenase

artículo científico publicado en 2017

Mouse islet of Langerhans isolation using a combination of purified collagenase and neutral protease

artículo científico publicado en 2012

Noninvasive assessment of pancreatic beta-cell function in vivo with manganese-enhanced magnetic resonance imaging

artículo científico publicado en 2008

Palmitate induces mRNA translation and increases ER protein load in islet β-cells via activation of the mammalian target of rapamycin pathway

artículo científico publicado en 2014

Peroxisome proliferator-activated receptor gamma activation restores islet function in diabetic mice through reduction of endoplasmic reticulum stress and maintenance of euchromatin structure

artículo científico publicado en 2009

Persistent elevations in circulating INS DNA among subjects with longstanding type 1 diabetes

scientific article published on 24 August 2018

Profiling of RNAs from Human Islet-Derived Exosomes in a Model of Type 1 Diabetes

scientific article published on 25 November 2019

Proinsulin Secretion Is a Persistent Feature of Type 1 Diabetes

scientific article published on 10 December 2018

Protective effects of polyamine depletion in mouse models of type 1 diabetes: implications for therapy

artículo científico publicado en 2013

Response to Comment on Sims et al. Proinsulin Secretion Is a Persistent Feature of Type 1 Diabetes. Diabetes Care 2019;42:258-264

artículo científico publicado en 2019

Restructuring of the Gut Microbiome by Intermittent Fasting Prevents Retinopathy and Prolongs Survival in Mice

scientific article published on 30 April 2018

Single-Cell Transcriptional Profiling of Mouse Islets Following Short-Term Obesogenic Dietary Intervention

scientific article published on 18 December 2020

Sirtuin 6 regulates glucose-stimulated insulin secretion in mouse pancreatic beta cells

artículo científico publicado en 2015

The role of beta-cell dysfunction in early type 1 diabetes

artículo científico publicado en 2020

The unique hypusine modification of eIF5A promotes islet beta cell inflammation and dysfunction in mice

artículo científico publicado en 2010

Transcriptional activity of the islet β cell factor Pdx1 is augmented by lysine methylation catalyzed by the methyltransferase Set7/9.

artículo científico publicado en 2015

eIF5A inhibition influences T cell dynamics in the pancreatic microenvironment of the humanized mouse model of Type 1 Diabetes

artículo científico publicado en 2019

Lista de obras de Raghavendra Mirmira

1,25-Dihydroxyvitamin D3 enhances glucose-stimulated insulin secretion in mouse and human islets: a role for transcriptional regulation of voltage-gated calcium channels by the vitamin D receptor

12-lipoxygenase promotes obesity-induced oxidative stress in pancreatic islets

A Versatile, Portable Intravital Microscopy Platform for Studying Beta-cell Biology In Vivo

A zebrafish tailfin injury assay protocol for quantifying immune cell migration and infiltration

Abnormalities in proinsulin processing in islets from individuals with longstanding T1D

Amelioration of type 1 diabetes following treatment of non-obese diabetic mice with INGAP and lisofylline.

An In Vivo Zebrafish Model for Interrogating ROS-Mediated Pancreatic β-Cell Injury, Response, and Prevention.

Analysis of serum Hsp90 as a potential biomarker of β cell autoimmunity in type 1 diabetes

Biomarkers of islet beta cell stress and death in type 1 diabetes

Biomarkers of β-Cell Stress and Death in Type 1 Diabetes

Cellular metabolism constrains innate immune responses in early human ontogeny

Chronic high fat feeding restricts islet mRNA translation initiation independently of ER stress via DNA damage and p53 activation

Circulating unmethylated CHTOP and INS DNA fragments provide evidence of possible islet cell death in youth with obesity and diabetes

Deletion of 12/15-lipoxygenase alters macrophage and islet function in NOD-Alox15(null) mice, leading to protection against type 1 diabetes development

Deoxyhypusine synthase haploinsufficiency attenuates acute cytokine signaling

Detection of islet β-cell death in vivo by multiplex PCR analysis of differentially methylated DNA.

Divergent compensatory responses to high-fat diet between C57BL6/J and C57BLKS/J inbred mouse strains

Elevated unmethylated and methylated insulin DNA are unique markers of A+β+ ketosis prone diabetes

Elevations in Circulating Methylated and Unmethylated Preproinsulin DNA in New-Onset Type 1 Diabetes

Elevations in the Fasting Serum Proinsulin-to-C-Peptide Ratio Precede the Onset of Type 1 Diabetes

Hypoglycemia in a Patient With a Polyhormonal Pancreatic Neuroendocrine Tumor With Evidence of Endocrine Progenitors.

Hypusinated eIF5A is expressed in the pancreas and spleen of individuals with type 1 and type 2 diabetes

Hypusine biosynthesis in β cells links polyamine metabolism to facultative cellular proliferation to maintain glucose homeostasis

Immune reconstitution in ART treated, but not untreated HIV infection, is associated with abnormal beta cell function.

Inhibition of 12/15-Lipoxygenase Protects Against β Cell Oxidative Stress and Glycemic Deterioration in Mouse Models of Type 1 Diabetes.

Inhibition of deoxyhypusine synthase enhances islet {beta} cell function and survival in the setting of endoplasmic reticulum stress and type 2 diabetes

Interleukin-6 Reduces β-Cell Oxidative Stress by Linking Autophagy With the Antioxidant Response

Islet β-cell endoplasmic reticulum stress precedes the onset of type 1 diabetes in the nonobese diabetic mouse model

Longitudinal Intravital Imaging of Biosensor-labeled In Situ Islet Beta Cells

Loss of Free Fatty Acid Receptor 2 leads to impaired islet mass and beta cell survival

Maintenance of Pdx1 mRNA translation in islet β-cells during the unfolded protein response

Measurement of Differentially Methylated INS DNA Species in Human Serum Samples as a Biomarker of Islet β Cell Death

Minireview: 12-Lipoxygenase and Islet β-Cell Dysfunction in Diabetes

Molecular mechanisms of nonalcoholic fatty liver disease: Potential role for 12-lipoxygenase

Mouse islet of Langerhans isolation using a combination of purified collagenase and neutral protease

Noninvasive assessment of pancreatic beta-cell function in vivo with manganese-enhanced magnetic resonance imaging

Palmitate induces mRNA translation and increases ER protein load in islet β-cells via activation of the mammalian target of rapamycin pathway

Peroxisome proliferator-activated receptor gamma activation restores islet function in diabetic mice through reduction of endoplasmic reticulum stress and maintenance of euchromatin structure

Persistent elevations in circulating INS DNA among subjects with longstanding type 1 diabetes

Profiling of RNAs from Human Islet-Derived Exosomes in a Model of Type 1 Diabetes

Proinsulin Secretion Is a Persistent Feature of Type 1 Diabetes

Protective effects of polyamine depletion in mouse models of type 1 diabetes: implications for therapy

Response to Comment on Sims et al. Proinsulin Secretion Is a Persistent Feature of Type 1 Diabetes. Diabetes Care 2019;42:258-264

Restructuring of the Gut Microbiome by Intermittent Fasting Prevents Retinopathy and Prolongs Survival in Mice

Single-Cell Transcriptional Profiling of Mouse Islets Following Short-Term Obesogenic Dietary Intervention

Sirtuin 6 regulates glucose-stimulated insulin secretion in mouse pancreatic beta cells

The role of beta-cell dysfunction in early type 1 diabetes

The unique hypusine modification of eIF5A promotes islet beta cell inflammation and dysfunction in mice

Transcriptional activity of the islet β cell factor Pdx1 is augmented by lysine methylation catalyzed by the methyltransferase Set7/9.

eIF5A inhibition influences T cell dynamics in the pancreatic microenvironment of the humanized mouse model of Type 1 Diabetes