Lista de obras -

6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling

artículo científico publicado en 2015

A mitochondrial RNAi screen defines cellular bioenergetic determinants and identifies an adenylate kinase as a key regulator of ATP levels

artículo científico publicado en 2014

A nanobuffer reporter library for fine-scale imaging and perturbation of endocytic organelles

artículo científico publicado en 2015

A roadmap for interpreting (13)C metabolite labeling patterns from cells

artículo científico publicado en 2015

A role for the mitochondrial pyruvate carrier as a repressor of the Warburg effect and colon cancer cell growth

artículo científico publicado en 2014

Analysis of cancer metabolism by imaging hyperpolarized nuclei: prospects for translation to clinical research.

artículo científico publicado en 2011

Both GLS silencing and GLS2 overexpression synergize with oxidative stress against proliferation of glioma cells.

artículo científico publicado en 2013

Brick by brick: metabolism and tumor cell growth

artículo científico publicado en 2008

Cancer. Silencing a metabolic oncogene

artículo científico publicado en 2013

Cell-autonomous immune gene expression is repressed in pulmonary neuroendocrine cells and small cell lung cancer

artículo científico publicado en 2021

D2HGDH regulates alpha-ketoglutarate levels and dioxygenase function by modulating IDH2

artículo científico publicado en 2015

Designing a broad-spectrum integrative approach for cancer prevention and treatment.

artículo científico publicado en 2015

Dysregulated metabolism contributes to oncogenesis

artículo científico publicado en 2015

Evidence of Glycolysis Up-Regulation and Pyruvate Mitochondrial Oxidation Mismatch During Mechanical Unloading of the Failing Human Heart: Implications for Cardiac Reloading and Conditioning

artículo científico publicado en 2016

Exploring a glycolytic inhibitor for the treatment of an FH-deficient type-2 papillary RCC

artículo científico publicado en 2011

Fundamentals of cancer metabolism

artículo científico publicado en 2016

Genetically-defined metabolic reprogramming in cancer

artículo científico publicado en 2012

Glutamate dehydrogenase 1 signals through antioxidant glutathione peroxidase 1 to regulate redox homeostasis and tumor growth

artículo científico publicado en 2015

Glutamine and cancer: cell biology, physiology, and clinical opportunities

artículo científico publicado en 2013

Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase

artículo científico publicado en 2011

Hyperpolarized (13)C Magnetic Resonance and Its Use in Metabolic Assessment of Cultured Cells and Perfused Organs

artículo científico publicado en 2015

Hypoxic metabolism in human hematopoietic stem cells.

artículo científico publicado en 2015

In vivo analysis of lung cancer metabolism: nothing like the real thing

artículo científico publicado en 2015

In vivo detection of citrate in brain tumors by 1H magnetic resonance spectroscopy at 3T.

artículo científico publicado en 2013

Inhibition of cancer cell proliferation by PPARγ is mediated by a metabolic switch that increases reactive oxygen species levels

artículo científico publicado en 2014

Lysine acetylation activates 6-phosphogluconate dehydrogenase to promote tumor growth.

artículo científico publicado en 2014

Measurement of glycine in the human brain in vivo by 1H‐MRS at 3 T: application in brain tumors ⬇️

artículo científico publicado el 9 de marzo de 2011

Mechanism by which a recently discovered allosteric inhibitor blocks glutamine metabolism in transformed cells

artículo científico publicado en 2014

Metabolic pathways promoting cancer cell survival and growth

artículo científico publicado en 2015

Metabolic plasticity maintains proliferation in pyruvate dehydrogenase deficient cells

artículo científico publicado en 2015

Metabolic regulation of transcription through compartmentalized NAD+ biosynthesis.

artículo científico publicado en 2018

Metabolic reprogramming and cancer progression

scientific article published on 01 April 2020

Metformin Antagonizes Cancer Cell Proliferation by Suppressing Mitochondrial-Dependent Biosynthesis

artículo científico publicado en 2015

Mitochondrial reactive oxygen species promote epidermal differentiation and hair follicle development

artículo científico publicado en 2013

Oxidation of alpha-ketoglutarate is required for reductive carboxylation in cancer cells with mitochondrial defects.

artículo científico publicado en 2014

Phosphoglycerate Mutase 1 Coordinates Glycolysis and Biosynthesis to Promote Tumor Growth

artículo científico publicado en 2012

Principles of reproducible metabolite profiling of enriched lymphocytes in tumors and ascites from human ovarian cancer

artículo científico publicado en 2022

Pyruvate carboxylase is required for glutamine-independent growth of tumor cells ⬇️

artículo científico publicado el 9 de mayo de 2011

RETRACTED: MAVS, cGAS, and endogenous retroviruses in T-independent B cell responses

artículo científico publicado en 2014

Real-time detection of hepatic gluconeogenic and glycogenolytic states using hyperpolarized [2-13C]dihydroxyacetone

artículo científico publicado en 2014

Reductive carboxylation supports growth in tumour cells with defective mitochondria.

artículo científico publicado en 2011

Role of Glutamine in Cancer: Therapeutic and Imaging Implications: FIGURE 1 ⬇️

artículo científico publicado el 16 de junio de 2011

Role of PFKFB3-driven glycolysis in vessel sprouting

artículo científico publicado en 2013

Spectrum of mutations in the renin-angiotensin system genes in autosomal recessive renal tubular dysgenesis.

artículo científico publicado en 2011

Stable isotope tracing to assess tumor metabolism in vivo

artículo científico publicado en 2021

The abundance of metabolites related to protein methylation correlates with the metastatic capacity of human melanoma xenografts.

artículo científico publicado en 2017

The distinct metabolic profile of hematopoietic stem cells reflects their location in a hypoxic niche.

artículo científico publicado en 2010

The gut commensal Bacteroides thetaiotaomicron exacerbates enteric infection through modification of the metabolic landscape.

artículo científico publicado en 2014

The hexosamine biosynthesis pathway is a targetable liability in KRAS/LKB1 mutant lung cancer

artículo científico publicado en 2020

The proto-oncometabolite fumarate binds glutathione to amplify ROS-dependent signaling.

artículo científico publicado en 2013

The transcription factor HIF-1alpha plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysis

scientific journal article

Toll-like receptor-induced changes in glycolytic metabolism regulate dendritic cell activation

artículo científico publicado en 2010

Using arterial-venous analysis to characterize cancer metabolic consumption in patients

artículo científico publicado en 2020

We need to talk about the Warburg effect

artículo científico publicado en 2020

Lista de obras de

6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling

A mitochondrial RNAi screen defines cellular bioenergetic determinants and identifies an adenylate kinase as a key regulator of ATP levels

A nanobuffer reporter library for fine-scale imaging and perturbation of endocytic organelles

A roadmap for interpreting (13)C metabolite labeling patterns from cells

A role for the mitochondrial pyruvate carrier as a repressor of the Warburg effect and colon cancer cell growth

Analysis of cancer metabolism by imaging hyperpolarized nuclei: prospects for translation to clinical research.

Both GLS silencing and GLS2 overexpression synergize with oxidative stress against proliferation of glioma cells.

Brick by brick: metabolism and tumor cell growth

Cancer. Silencing a metabolic oncogene

Cell-autonomous immune gene expression is repressed in pulmonary neuroendocrine cells and small cell lung cancer

D2HGDH regulates alpha-ketoglutarate levels and dioxygenase function by modulating IDH2

Designing a broad-spectrum integrative approach for cancer prevention and treatment.

Dysregulated metabolism contributes to oncogenesis

Evidence of Glycolysis Up-Regulation and Pyruvate Mitochondrial Oxidation Mismatch During Mechanical Unloading of the Failing Human Heart: Implications for Cardiac Reloading and Conditioning

Exploring a glycolytic inhibitor for the treatment of an FH-deficient type-2 papillary RCC

Fundamentals of cancer metabolism

Genetically-defined metabolic reprogramming in cancer

Glutamate dehydrogenase 1 signals through antioxidant glutathione peroxidase 1 to regulate redox homeostasis and tumor growth

Glutamine and cancer: cell biology, physiology, and clinical opportunities

Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase

Hyperpolarized (13)C Magnetic Resonance and Its Use in Metabolic Assessment of Cultured Cells and Perfused Organs

Hypoxic metabolism in human hematopoietic stem cells.

In vivo analysis of lung cancer metabolism: nothing like the real thing

In vivo detection of citrate in brain tumors by 1H magnetic resonance spectroscopy at 3T.

Inhibition of cancer cell proliferation by PPARγ is mediated by a metabolic switch that increases reactive oxygen species levels

Lysine acetylation activates 6-phosphogluconate dehydrogenase to promote tumor growth.

Measurement of glycine in the human brain in vivo by 1H‐MRS at 3 T: application in brain tumors ⬇️

Mechanism by which a recently discovered allosteric inhibitor blocks glutamine metabolism in transformed cells

Metabolic pathways promoting cancer cell survival and growth

Metabolic plasticity maintains proliferation in pyruvate dehydrogenase deficient cells

Metabolic regulation of transcription through compartmentalized NAD+ biosynthesis.

Metabolic reprogramming and cancer progression

Metformin Antagonizes Cancer Cell Proliferation by Suppressing Mitochondrial-Dependent Biosynthesis

Mitochondrial reactive oxygen species promote epidermal differentiation and hair follicle development

Oxidation of alpha-ketoglutarate is required for reductive carboxylation in cancer cells with mitochondrial defects.

Phosphoglycerate Mutase 1 Coordinates Glycolysis and Biosynthesis to Promote Tumor Growth

Principles of reproducible metabolite profiling of enriched lymphocytes in tumors and ascites from human ovarian cancer

Pyruvate carboxylase is required for glutamine-independent growth of tumor cells ⬇️

RETRACTED: MAVS, cGAS, and endogenous retroviruses in T-independent B cell responses

Real-time detection of hepatic gluconeogenic and glycogenolytic states using hyperpolarized [2-13C]dihydroxyacetone

Reductive carboxylation supports growth in tumour cells with defective mitochondria.

Role of Glutamine in Cancer: Therapeutic and Imaging Implications: FIGURE 1 ⬇️

Role of PFKFB3-driven glycolysis in vessel sprouting

Spectrum of mutations in the renin-angiotensin system genes in autosomal recessive renal tubular dysgenesis.

Stable isotope tracing to assess tumor metabolism in vivo

The abundance of metabolites related to protein methylation correlates with the metastatic capacity of human melanoma xenografts.

The distinct metabolic profile of hematopoietic stem cells reflects their location in a hypoxic niche.

The gut commensal Bacteroides thetaiotaomicron exacerbates enteric infection through modification of the metabolic landscape.

The hexosamine biosynthesis pathway is a targetable liability in KRAS/LKB1 mutant lung cancer

The proto-oncometabolite fumarate binds glutathione to amplify ROS-dependent signaling.

The transcription factor HIF-1alpha plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysis

Toll-like receptor-induced changes in glycolytic metabolism regulate dendritic cell activation

Using arterial-venous analysis to characterize cancer metabolic consumption in patients

We need to talk about the Warburg effect