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A Multi-Crystal Method for Extracting Obscured Signal from Crystallographic Electron Density

article published in 2016

A generic protocol for protein crystal dehydration using the HC1b humidity controller.

artículo científico publicado en 2016

A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density

artículo científico publicado en 2017

Advances and challenges in understanding histone demethylase biology.

artículo científico publicado en 2016

An integrated approach to quantitative modelling in angiogenesis research

artículo científico publicado en 2015

Chemically Induced Degradation of Anaplastic Lymphoma Kinase (ALK).

artículo científico publicado en 2018

Docking and Linking of Fragments To Discover Jumonji Histone Demethylase Inhibitors.

artículo científico publicado en 2015

Early cross-coronavirus reactive signatures of humoral immunity against COVID-19

artículo científico publicado en 2021

Plasticity in binding confers selectivity in ligand-induced protein degradation

artículo científico publicado en 2018

Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells

artículo científico publicado en 2017

Rapid 'mix and read' assay for scalable detection of SARS-CoV-2 antibodies in patient plasma

scientific article published on 03 September 2020

Small molecule degraders of the hepatitis C virus protease reduce susceptibility to resistance mutations

artículo científico publicado en 2019

Small-molecule-induced polymerization triggers degradation of BCL6

artículo científico publicado en 2020

Structural analysis of human KDM5B guides histone demethylase inhibitor development

artículo científico publicado en 2016

Structural complementarity facilitates E7820-mediated degradation of RBM39 by DCAF15

artículo científico publicado en 2019

Structure of the Human cGAS-DNA Complex Reveals Enhanced Control of Immune Surveillance

scientific article published on 01 July 2018

Studies on the Interaction of the Histone Demethylase KDM5B with Tricarboxylic Acid Cycle Intermediates.

artículo científico publicado en 2017

Targeted protein degradation as a powerful research tool in basic biology and drug target discovery

artículo científico publicado en 2020

The roles of Jumonji-type oxygenases in human disease

artículo científico

Tubulin Resists Degradation by Cereblon-Recruiting PROTACs

artículo científico publicado en 2020