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A crucial role for tumor necrosis factor receptor 1 in synovial lining cells and the reticuloendothelial system in mediating experimental arthritis

artículo científico publicado en 2010

A novel Saa3-promoter reporter distinguishes inflammatory subtypes in experimental arthritis and human synovial fibroblasts

artículo científico publicado el 7 de abril de 2011

A tail-anchored myotonic dystrophy protein kinase isoform induces perinuclear clustering of mitochondria, autophagy, and apoptosis

artículo científico publicado en 2009

Adenoviral transfer of murine oncostatin M elicits periosteal bone apposition in knee joints of mice, despite synovial inflammation and up-regulated expression of interleukin-6 and receptor activator of nuclear factor-kappa B ligand

artículo científico publicado en 2002

Commensal microbiota influence systemic autoimmune responses.

artículo científico publicado en 2015

Commercial cow milk contains physically stable extracellular vesicles expressing immunoregulatory TGF-β.

artículo científico publicado en 2015

Complementary action of granulocyte macrophage colony-stimulating factor and interleukin-17A induces interleukin-23, receptor activator of nuclear factor-κB ligand, and matrix metalloproteinases and drives bone and cartilage pathology in experimenta

artículo científico publicado en 2015

Computational design and application of endogenous promoters for transcriptionally targeted gene therapy for rheumatoid arthritis

artículo científico publicado en 2009

Deficiency of NADPH Oxidase Components p47phox and gp91phox Caused Granulomatous Synovitis and Increased Connective Tissue Destruction in Experimental Arthritis Models

artículo científico publicado el 1 de octubre de 2003

Destructive role of myeloid differentiation factor 88 and protective role of TRIF in interleukin-17-dependent arthritis in mice

artículo científico publicado en 2011

Disease-Regulated Gene Therapy with Anti-Inflammatory Interleukin-10 Under the Control of the CXCL10 Promoter for the Treatment of Rheumatoid Arthritis

artículo científico publicado en 2015

Disease-dependent local IL-10 production ameliorates collagen induced arthritis in mice

artículo científico publicado en 2012

Disease-regulated local IL-10 gene therapy diminishes synovitis and cartilage proteoglycan depletion in experimental arthritis.

artículo científico publicado en 2014

Divergent mitochondrial and endoplasmic reticulum association of DMPK splice isoforms depends on unique sequence arrangements in tail anchors.

artículo científico publicado en 2005

Elevated extracellular matrix production and degradation upon bone morphogenetic protein-2 (BMP-2) stimulation point toward a role for BMP-2 in cartilage repair and remodeling

artículo científico publicado en 2007

Enhanced suppressor of cytokine signaling 3 in arthritic cartilage dysregulates human chondrocyte function

artículo científico publicado en 2012

Functional Tissue Analysis Reveals Successful Cryopreservation of Human Osteoarthritic Synovium

artículo científico publicado en 2016

Gene therapy for rheumatoid arthritis. Lessons from animal models, including studies on interleukin-4, interleukin-10, and interleukin-1 receptor antagonist as potential disease modulators

artículo científico publicado en 2002

Gene therapy in animal models of rheumatoid arthritis: are we ready for the patients?

artículo científico publicado en 2004

Gene therapy works in animal models of rheumatoid arthritis...so what!

artículo científico publicado en 2006

Genetic modification of ER-Hoxb8 osteoclast precursors using CRISPR/Cas9 as a novel way to allow studies on osteoclast biology.

artículo científico publicado en 2016

Higher efficacy of anti-IL-6/IL-21 combination therapy compared to monotherapy in the induction phase of Th17-driven experimental arthritis

artículo científico publicado en 2017

How to build an inducible cartilage-specific transgenic mouse

artículo científico publicado en 2014

IL-32, a proinflammatory cytokine in rheumatoid arthritis

artículo científico publicado en 2006

IL37 dampens the IL1β-induced catabolic status of human OA chondrocytes

artículo científico publicado en 2016

Immunocytokines: the long awaited therapeutic magic bullet in rheumatoid arthritis?

artículo científico publicado en 2009

Inducible chondrocyte-specific overexpression of BMP2 in young mice results in severe aggravation of osteophyte formation in experimental OA without altering cartilage damage

scientific article published on 21 January 2014

Inducible nitric oxide synthase mediates bone loss in ovariectomized mice

artículo científico publicado en 2003

Inducible nitric oxide synthase-deficient mice exhibit resistance to the acute pancreatitis induced by cerulein

artículo científico publicado en 2002

Induction of Canonical Wnt Signaling by Synovial Overexpression of Selected Wnts Leads to Protease Activity and Early Osteoarthritis-Like Cartilage Damage

artículo científico publicado en 2015

Inflammation-dependent secretion and splicing of IL-32{gamma} in rheumatoid arthritis

artículo científico publicado en 2011

Inflammation-responsive promoters for fine-tuned gene therapy in rheumatoid arthritis

artículo científico publicado en 2004

Interleukin-18 promotes joint inflammation and induces interleukin-1-driven cartilage destruction

artículo científico publicado en 2004

Interleukin-21 receptor deficiency increases the initial toll-like receptor 2 response but protects against joint pathology by reducing Th1 and Th17 cells during streptococcal cell wall arthritis

artículo científico publicado en 2014

Intravenous delivery of HIV-based lentiviral vectors preferentially transduces F4/80+ and Ly-6C+ cells in spleen, important target cells in autoimmune arthritis

artículo científico publicado en 2013

Local interleukin-1-driven joint pathology is dependent on toll-like receptor 4 activation

artículo científico publicado en 2009

Local interleukin-12 gene transfer promotes conversion of an acute arthritis to a chronic destructive arthritis.

artículo científico publicado en 2002

NADPH-oxidase-driven oxygen radical production determines chondrocyte death and partly regulates metalloproteinase-mediated cartilage matrix degradation during interferon-gamma-stimulated immune complex arthritis

artículo científico publicado en 2005

Oral administration of bovine milk derived extracellular vesicles attenuates arthritis in two mouse models

artículo científico publicado en 2015

Organ damage in zymosan-induced multiple organ dysfunction syndrome in mice is not mediated by inducible nitric oxide synthase

artículo científico publicado en 2002

Periodontal pathogens directly promote autoimmune experimental arthritis by inducing a TLR2- and IL-1-driven Th17 response

artículo científico publicado en 2014

Regulation of prostaglandin generation in carrageenan-induced pleurisy by inducible nitric oxide synthase in knockout mice

artículo científico publicado en 2003

Role of gene therapy in tissue engineering procedures in rheumatology: the use of animal models

artículo científico publicado en 2004

Role of induced nitric oxide in the initiation of the inflammatory response after postischemic injury

artículo científico publicado en 2002

S100A8/A9 increases the mobilization of pro-inflammatory Ly6Chigh monocytes to the synovium during experimental osteoarthritis.

artículo científico publicado en 2017

S100A8/A9, a potent serum and molecular imaging biomarker for synovial inflammation and joint destruction in seronegative experimental arthritis

scientific article published on 24 October 2016

Selective Increment of Synovial Soluble TYRO3 Correlates with Disease Severity and Joint Inflammation in Patients with Rheumatoid Arthritis

artículo científico publicado en 2020

Serum Amyloid A3 Gene Expression in Adipocytes is an Indicator of the Interaction with Macrophages

scientific article published on 08 December 2016

Serum samples that have been stored long-term (>10 years) can be used as a suitable data source for developing cardiovascular risk prediction models in large observational rheumatoid arthritis cohorts

artículo científico publicado en 2014

Soluble IL-18 receptor complex: a new star in the firmament of rheumatoid arthritis diagnosis?

artículo científico publicado el 27 de abril de 2011

Suppression of the inflammatory response by disease-inducible interleukin-10 gene therapy in a three-dimensional micromass model of the human synovial membrane

artículo científico publicado en 2016

Synergy between 15-lipoxygenase and secreted PLA2 promotes inflammation by formation of TLR4 agonists from extracellular vesicles

scientific article published on 24 September 2020

T cell lessons from the rheumatoid arthritis synovium SCID mouse model: CD3-rich synovium lacks response to CTLA-4ig but is successfully treated by interleukin-17 neutralization

article

TGF-β is a potent inducer of Nerve Growth Factor in articular cartilage via the ALK5-Smad2/3 pathway. Potential role in OA related pain?

artículo científico publicado en 2014

Tetraspanin CD37 protects against the development of B cell lymphoma

artículo científico publicado en 2016

The in-vivo use of superparamagnetic iron oxide nanoparticles to detect inflammation elicits a cytokine response but does not aggravate experimental arthritis

artículo científico publicado en 2015

Trapped in a vicious loop: Toll-like receptors sustain the spontaneous cytokine production by rheumatoid synovium

artículo científico publicado el 30 de marzo de 2011

Treatment of collagenase-induced osteoarthritis with a viral vector encoding TSG-6 results in ectopic bone formation.

artículo científico publicado en 2018

Tumor Necrosis Factor, but Not Neutrophils, Alters the Metabolic Profile in Acute Experimental Arthritis

artículo científico publicado en 2016

Tumor marker nucleoporin 88 kDa regulates nucleocytoplasmic transport of NF-kappaB.

artículo científico publicado en 2008

Tyro3/Axl/Mertk-deficient mice develop bone marrow edema which is an early pathological marker in rheumatoid arthritis

artículo científico publicado en 2018