Lista de obras - Frank Sobott - Dominio Público Uruguay

A broader view on ion heating in traveling-wave devices using fragmentation of CsI clusters and extent of H˙ migration as molecular thermometers ⬇️

artículo científico

A cryo-EM grid preparation device for time-resolved structural studies

artículo científico publicado en 2019

A homologue of the Parkinson's disease-associated protein LRRK2 undergoes a monomer-dimer transition during GTP turnover ⬇️

artículo científico publicado en 2017

A tandem mass spectrometer for improved transmission and analysis of large macromolecular assemblies.

artículo científico publicado en 2002

ATP and autophosphorylation driven conformational changes of HipA kinase revealed by ion mobility and crosslinking mass spectrometry. ⬇️

artículo científico publicado en 2016

Advances in native high-performance liquid chromatography and intact mass spectrometry for the characterization of biopharmaceutical products. ⬇️

artículo científico publicado en 2017

Analysis of the PcrA-RNA polymerase complex reveals a helicase interaction motif and a role for PcrA/UvrD helicase in the suppression of R-loops

scientific article published on 19 July 2021

Analysis of the natively unstructured RNA/protein-recognition core in the Escherichia coli RNA degradosome and its interactions with regulatory RNA/Hfq complexes ⬇️

artículo científico publicado en 2017

Analyzing complex mixtures of drug-like molecules: Ion mobility as an adjunct to existing liquid chromatography-(tandem) mass spectrometry methods ⬇️

artículo científico

Antarctic fish versus human cytoglobins - The same but yet so different ⬇️

artículo científico publicado en 2017

Apparent activation energies of protein-protein complex dissociation in the gas-phase determined by electrospray mass spectrometry. ⬇️

artículo científico publicado en 2017

Application of a proteolysis/mass spectrometry method for investigating the effects of inhibitors on hydroxylase structure.

artículo científico publicado en 2009

AtaT blocks translation initiation by N-acetylation of the initiator tRNAfMet ⬇️

artículo científico publicado en 2017

Biochemical and structural studies of the interaction of Cdc37 with Hsp90.

artículo científico publicado en 2004

Biophysical studies on interactions and assembly of full-size E3 ubiquitin ligase: suppressor of cytokine signaling 2 (SOCS2)-elongin BC-cullin 5-ring box protein 2 (RBX2).

artículo científico publicado en 2014

Bouncing off the Walls: Excited Protein Complexes Tell Their Story

artículo científico publicado en 2015

Cation Selectivity of Natural and Synthetic Ionophores Probed with Laser-Induced Liquid Beam Mass Spectrometry ⬇️

artículo científico publicado el 1 de septiembre de 1997

Characterising electrosprayed biomolecules using tandem-MS—the noncovalent GroEL chaperonin assembly

Characterization of Vibrio cholerae Hfq provides novel insights into the role of the Hfq C-terminal region

artículo científico publicado en 2012

Characterization of top-down ETD in a travelling-wave ion guide

artículo científico publicado en 2015

Characterization of β2-microglobulin conformational intermediates associated to different fibrillation conditions

article published in 2011

Codon optimization can improve expression of human genes in Escherichia coli: A multi-gene study.

artículo científico publicado en 2008

Combining density functional theory (DFT) and collision cross-section (CCS) calculations to analyze the gas-phase behaviour of small molecules and their protonation site isomers ⬇️

artículo científico publicado en 2016

Compaction properties of an intrinsically disordered protein: Sic1 and its kinase-inhibitor domain

artículo científico publicado en 2011

Comparison of CID versus ETD based MS/MS fragmentation for the analysis of protein ubiquitination.

artículo científico publicado en 2009

Conformational Space and Stability of ETD Charge Reduction Products of Ubiquitin ⬇️

artículo científico publicado en 2016

Conformational footprinting of proteins using a combination of top-down electron transfer dissociation and ion mobility

article

Contactin-associated protein-2 antibodies in non-paraneoplastic cerebellar ataxia

artículo científico publicado en 2012

Covalent adducts of melphalan with free amino acids and a model peptide studied by liquid chromatography/tandem mass spectrometry

artículo científico publicado en 2016

Development of a novel antibody-tetrazine conjugate for bioorthogonal pretargeting

artículo científico publicado en 2016

Differences in the Elemental Isotope Definition May Lead to Errors in Modern Mass-Spectrometry-Based Proteomics

artículo científico publicado en 2015

Do Aptamers Always Bind? The Need for a Multifaceted Analytical Approach When Demonstrating Binding Affinity between Aptamer and Low Molecular Weight Compounds

artículo científico publicado en 2020

ETD allows for native surface mapping of a 150 kDa noncovalent complex on a commercial Q-TWIMS-TOF instrument

artículo científico publicado en 2014

Editorial and Review: 30th ASMS Sanibel Conference on Mass Spectrometry-Computational Modelling in Mass Spectrometry and Ion Mobility: Methods for Ion Structure and Reactivity Determination ⬇️

article

Effects of Detergent on α-Synuclein Structure. A Native MS-Ion Mobility Study

artículo científico publicado en 2020

Electron transfer dissociation provides higher-order structural information of native and partially unfolded protein complexes

artículo científico publicado en 2015

Estimation of Rates of Reactions Triggered by Electron Transfer in Top-Down Mass Spectrometry ⬇️

artículo científico publicado en 2017

Estimation of Rates of Reactions Triggered by Electron Transfer in Top-Down Mass Spectrometry

artículo científico publicado en 2017

Evaluation of ion mobility for the separation of glycoconjugate isomers due to different types of sialic acid linkage, at the intact glycoprotein, glycopeptide and glycan level ⬇️

artículo científico publicado en 2017

Examination of Condensation Products of Group 4 Alkoxides with Laser-Induced Liquid Beam Ionization/Desorption Mass Spectrometry

Extending native mass spectrometry approaches to integral membrane proteins

artículo científico publicado en 2015

Extensive Charge Reduction and Dissociation of Intact Protein Complexes Following Electron Transfer on a Quadrupole-Ion Mobility-Time-of-Flight MS.

artículo científico publicado en 2015

Fixed-Charge Trimethyl Pyrilium Modification for Enabling Enhanced Top-Down Mass Spectrometry Sequencing of Intact Protein Complexes. ⬇️

artículo científico publicado en 2018

Gas-phase dissociation pathways of a tetrameric protein complex

artículo científico publicado en 2003

Gas-phase microsolvation of ubiquitin: investigation of crown ether complexation sites using ion mobility-mass spectrometry ⬇️

artículo científico publicado en 2016

Global structural changes of an ion channel during its gating are followed by ion mobility mass spectrometry

artículo científico publicado en 2014

Heptameric (L12)6/L10 rather than canonical pentameric complexes are found by tandem MS of intact ribosomes from thermophilic bacteria.

artículo científico publicado en 2005

Hfq binding changes the structure of Escherichia coli small noncoding RNAs OxyS and RprA, which are involved in the riboregulation of rpoS

artículo científico publicado en 2013

Hidden States within Disordered Regions of the CcdA Antitoxin Protein ⬇️

artículo científico publicado en 2017

High-Resolution Hydrogen–Deuterium Protection Factors from Sparse Mass Spectrometry Data Validated by Nuclear Magnetic Resonance Measurements

artículo científico publicado en 2022

Interlaboratory Study for Characterizing Monoclonal Antibodies by Top-Down and Middle-Down Mass Spectrometry

artículo científico publicado en 2020

Ion mobility mass spectrometry for extracting spectra of N-glycans directly from incubation mixtures following glycan release: application to glycans from engineered glycoforms of intact, folded HIV gp120.

artículo científico publicado en 2011

Ionic clathrates from aqueous solutions detected with laser induced liquid beam ionization/desorption mass spectrometry

artículo científico publicado en 1999

Laser desorption mass spectrometry on thin liquid jets

artículo científico publicado en 1998

Lipids modulate the conformational dynamics of a secondary multidrug transporter ⬇️

artículo científico publicado en 2016

LptA assembles into rod-like oligomers involving disorder-to-order transitions

artículo científico publicado en 2013

Mechanisms of Peptide Oxidation by Hydroxyl Radicals: Insight at the Molecular Scale ⬇️

Metal and redox selectivity of protoporphyrin binding to the heme chaperone CcmE.

artículo científico publicado en 2011

Methionine oxidation in α-synuclein inhibits its propensity for ordered secondary structure

scientific article published on 12 February 2019

Molecular basis for structural heterogeneity of an intrinsically disordered protein bound to a partner by combined ESI-IM-MS and modeling

artículo científico publicado en 2014

Nanobody-aided crystallization of the transcription regulator PaaR2 from <i>Escherichia coli</i> O157:H7

artículo científico publicado en 2021

Native Mass Spectrometry for the Characterization of Structure and Interactions of Membrane Proteins

artículo científico publicado en 2017

Native ion mobility-mass spectrometry and related methods in structural biology

artículo científico publicado en 2012

Opposite Structural Effects of Epigallocatechin-3-gallate and Dopamine Binding to α-Synuclein ⬇️

artículo científico publicado en 2016

Organization of the BcgI restriction-modification protein for the cleavage of eight phosphodiester bonds in DNA.

artículo científico publicado en 2012

Organization of the BcgI restriction-modification protein for the transfer of one methyl group to DNA.

artículo científico publicado en 2012

Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics ⬇️

artículo científico publicado en 2017

Phosphorylation decelerates conformational dynamics in bacterial translation elongation factors. ⬇️

artículo científico publicado en 2018

Preprotein mature domains contain translocase targeting signals that are essential for secretion ⬇️

artículo científico publicado en 2017

Protein complexes gain momentum.

artículo científico publicado en 2002

Protomers of benzocaine: solvent and permittivity dependence

artículo científico publicado en 2015

Proton Dynamics in Protein Mass Spectrometry. ⬇️

artículo científico publicado en 2017

Quadrupole-time-of-flight mass spectrometer modified for higher-energy dissociation reduces protein assemblies to peptide fragments.

artículo científico publicado en 2009

Radical solutions: Principles and application of electron-based dissociation in mass spectrometry-based analysis of protein structure ⬇️

artículo científico publicado en 2018

Raman optical activity of human α -synuclein in intrinsically disordered, micelle-bound α -helical, molten globule and oligomeric β -sheet state ⬇️

article by Carl Mensch et al published 17 April 2017 in Journal of Raman Spectroscopy

Reactions of gold cluster cations Aun+ (n=1–12) with H2S and H2

artículo científico publicado en 2003

Sample deposition onto cryo-EM grids: from sprays to jets and back

scientific article published on 25 March 2020

Signal loss due to oligomerization in ELISA analysis of amyloid-beta can be recovered by a novel sample pre-treatment method

artículo científico publicado en 2015

Sizing up DNA nanostructure assembly with native mass spectrometry and ion mobility

artículo científico publicado en 2022

Speciation in Solution: Silicate Oligomers in Aqueous Solutions Detected by Mass Spectrometry

artículo científico publicado en 2000

Specific and non-specific interactions of ParB with DNA: implications for chromosome segregation

artículo científico publicado en 2015

Specific sequences in the N-terminal domain of human small heat-shock protein HSPB6 dictate preferential hetero-oligomerization with the orthologue HSPB1. ⬇️

artículo científico publicado en 2017

Structural and Functional Characterization of the Human Protein Kinase ASK1

artículo científico publicado en 2007

Structural basis for protein-protein interactions in the 14-3-3 protein family

artículo científico publicado en 2006

Structural plasticity of histones H3-H4 facilitates their allosteric exchange between RbAp48 and ASF1

artículo científico publicado en 2012

Structure of an Hsp90-Cdc37-Cdk4 complex.

artículo científico publicado en 2006

Structure of the human protein kinase MPSK1 reveals an atypical activation loop architecture

artículo científico publicado en 2008

Studying noncovalent protein complexes in aqueous solution with laser desorption mass spectrometry

artículo científico publicado en 2000

Subunit Exchange of Multimeric Protein Complexes

artículo científico publicado en 2002

Tandem Mass Spectrometry Reveals the Quaternary Organization of Macromolecular Assemblies

artículo científico publicado en 2006

Tandem mass spectrometry defines the stoichiometry and quaternary structural arrangement of tryptophan molecules in the multiprotein complex TRAP.

artículo científico publicado en 2004

The Escherichia coli RnlA-RnlB toxin-antitoxin complex: production, characterization and crystallization

scientific article published on 01 January 2020

The centaurin gamma-1 GTPase-like domain functions as an NTPase

artículo científico publicado en 2007

The co-chaperone p23 arrests the Hsp90 ATPase cycle to trap client proteins

artículo científico publicado en 2005

The effect of reactive oxygen and nitrogen species on the structure of cytoglobin: A potential tumor suppressor ⬇️

artículo científico publicado en 2018

The flight of macromolecular complexes in a mass spectrometer

artículo científico publicado en 2005

The intrinsically disordered domain of the antitoxin Phd chaperones the toxin Doc against irreversible inactivation and misfolding.

artículo científico publicado en 2014

The low-resolution solution structure of Vibrio cholerae Hfq in complex with Qrr1 sRNA

artículo científico publicado en 2012

The preferential heterodimerization of human small heat shock proteins HSPB1 and HSPB6 is dictated by the N-terminal domain ⬇️

artículo científico publicado en 2016

The structural basis for dynamic DNA binding and bridging interactions which condense the bacterial centromere ⬇️

artículo científico publicado en 2017

Thermal Dissociation of Multimeric Protein Complexes by Using Nanoelectrospray Mass Spectrometry

artículo científico publicado en 2003

Top-down mass spectrometry of intact membrane protein complexes reveals oligomeric state and sequence information in a single experiment.

artículo científico publicado en 2015

Travelling wave ion mobility and negative ion fragmentation for the structural determination of N-linked glycans

artículo científico publicado en 2013

Type III restriction endonucleases are heterotrimeric: comprising one helicase-nuclease subunit and a dimeric methyltransferase that binds only one specific DNA.

artículo científico publicado en 2014

Understanding reaction pathways in top-down ETD by dissecting isotope distributions: A mammoth task

artículo científico publicado en 2015

Lista de obras de Frank Sobott

A broader view on ion heating in traveling-wave devices using fragmentation of CsI clusters and extent of H˙ migration as molecular thermometers ⬇️

A cryo-EM grid preparation device for time-resolved structural studies

A homologue of the Parkinson's disease-associated protein LRRK2 undergoes a monomer-dimer transition during GTP turnover ⬇️

A tandem mass spectrometer for improved transmission and analysis of large macromolecular assemblies.

ATP and autophosphorylation driven conformational changes of HipA kinase revealed by ion mobility and crosslinking mass spectrometry. ⬇️

Advances in native high-performance liquid chromatography and intact mass spectrometry for the characterization of biopharmaceutical products. ⬇️

Analysis of the PcrA-RNA polymerase complex reveals a helicase interaction motif and a role for PcrA/UvrD helicase in the suppression of R-loops

Analysis of the natively unstructured RNA/protein-recognition core in the Escherichia coli RNA degradosome and its interactions with regulatory RNA/Hfq complexes ⬇️

Analyzing complex mixtures of drug-like molecules: Ion mobility as an adjunct to existing liquid chromatography-(tandem) mass spectrometry methods ⬇️

Antarctic fish versus human cytoglobins - The same but yet so different ⬇️

Apparent activation energies of protein-protein complex dissociation in the gas-phase determined by electrospray mass spectrometry. ⬇️

Application of a proteolysis/mass spectrometry method for investigating the effects of inhibitors on hydroxylase structure.

AtaT blocks translation initiation by N-acetylation of the initiator tRNAfMet ⬇️

Biochemical and structural studies of the interaction of Cdc37 with Hsp90.

Biophysical studies on interactions and assembly of full-size E3 ubiquitin ligase: suppressor of cytokine signaling 2 (SOCS2)-elongin BC-cullin 5-ring box protein 2 (RBX2).

Bouncing off the Walls: Excited Protein Complexes Tell Their Story

Cation Selectivity of Natural and Synthetic Ionophores Probed with Laser-Induced Liquid Beam Mass Spectrometry ⬇️

Characterising electrosprayed biomolecules using tandem-MS—the noncovalent GroEL chaperonin assembly

Characterization of Vibrio cholerae Hfq provides novel insights into the role of the Hfq C-terminal region

Characterization of top-down ETD in a travelling-wave ion guide

Characterization of β2-microglobulin conformational intermediates associated to different fibrillation conditions

Codon optimization can improve expression of human genes in Escherichia coli: A multi-gene study.

Combining density functional theory (DFT) and collision cross-section (CCS) calculations to analyze the gas-phase behaviour of small molecules and their protonation site isomers ⬇️

Compaction properties of an intrinsically disordered protein: Sic1 and its kinase-inhibitor domain

Comparison of CID versus ETD based MS/MS fragmentation for the analysis of protein ubiquitination.

Conformational Space and Stability of ETD Charge Reduction Products of Ubiquitin ⬇️

Conformational footprinting of proteins using a combination of top-down electron transfer dissociation and ion mobility

Contactin-associated protein-2 antibodies in non-paraneoplastic cerebellar ataxia

Covalent adducts of melphalan with free amino acids and a model peptide studied by liquid chromatography/tandem mass spectrometry

Development of a novel antibody-tetrazine conjugate for bioorthogonal pretargeting

Differences in the Elemental Isotope Definition May Lead to Errors in Modern Mass-Spectrometry-Based Proteomics

Do Aptamers Always Bind? The Need for a Multifaceted Analytical Approach When Demonstrating Binding Affinity between Aptamer and Low Molecular Weight Compounds

ETD allows for native surface mapping of a 150 kDa noncovalent complex on a commercial Q-TWIMS-TOF instrument

Editorial and Review: 30th ASMS Sanibel Conference on Mass Spectrometry-Computational Modelling in Mass Spectrometry and Ion Mobility: Methods for Ion Structure and Reactivity Determination ⬇️

Effects of Detergent on α-Synuclein Structure. A Native MS-Ion Mobility Study

Electron transfer dissociation provides higher-order structural information of native and partially unfolded protein complexes

Estimation of Rates of Reactions Triggered by Electron Transfer in Top-Down Mass Spectrometry ⬇️

Estimation of Rates of Reactions Triggered by Electron Transfer in Top-Down Mass Spectrometry

Evaluation of ion mobility for the separation of glycoconjugate isomers due to different types of sialic acid linkage, at the intact glycoprotein, glycopeptide and glycan level ⬇️

Examination of Condensation Products of Group 4 Alkoxides with Laser-Induced Liquid Beam Ionization/Desorption Mass Spectrometry

Extending native mass spectrometry approaches to integral membrane proteins

Extensive Charge Reduction and Dissociation of Intact Protein Complexes Following Electron Transfer on a Quadrupole-Ion Mobility-Time-of-Flight MS.

Fixed-Charge Trimethyl Pyrilium Modification for Enabling Enhanced Top-Down Mass Spectrometry Sequencing of Intact Protein Complexes. ⬇️

Gas-phase dissociation pathways of a tetrameric protein complex

Gas-phase microsolvation of ubiquitin: investigation of crown ether complexation sites using ion mobility-mass spectrometry ⬇️

Global structural changes of an ion channel during its gating are followed by ion mobility mass spectrometry

Heptameric (L12)6/L10 rather than canonical pentameric complexes are found by tandem MS of intact ribosomes from thermophilic bacteria.

Hfq binding changes the structure of Escherichia coli small noncoding RNAs OxyS and RprA, which are involved in the riboregulation of rpoS

Hidden States within Disordered Regions of the CcdA Antitoxin Protein ⬇️

High-Resolution Hydrogen–Deuterium Protection Factors from Sparse Mass Spectrometry Data Validated by Nuclear Magnetic Resonance Measurements

Interlaboratory Study for Characterizing Monoclonal Antibodies by Top-Down and Middle-Down Mass Spectrometry

Ion mobility mass spectrometry for extracting spectra of N-glycans directly from incubation mixtures following glycan release: application to glycans from engineered glycoforms of intact, folded HIV gp120.

Ionic clathrates from aqueous solutions detected with laser induced liquid beam ionization/desorption mass spectrometry

Laser desorption mass spectrometry on thin liquid jets

Lipids modulate the conformational dynamics of a secondary multidrug transporter ⬇️

LptA assembles into rod-like oligomers involving disorder-to-order transitions

Mechanisms of Peptide Oxidation by Hydroxyl Radicals: Insight at the Molecular Scale ⬇️

Metal and redox selectivity of protoporphyrin binding to the heme chaperone CcmE.

Methionine oxidation in α-synuclein inhibits its propensity for ordered secondary structure

Molecular basis for structural heterogeneity of an intrinsically disordered protein bound to a partner by combined ESI-IM-MS and modeling

Nanobody-aided crystallization of the transcription regulator PaaR2 from <i>Escherichia coli</i> O157:H7

Native Mass Spectrometry for the Characterization of Structure and Interactions of Membrane Proteins

Native ion mobility-mass spectrometry and related methods in structural biology

Opposite Structural Effects of Epigallocatechin-3-gallate and Dopamine Binding to α-Synuclein ⬇️

Organization of the BcgI restriction-modification protein for the cleavage of eight phosphodiester bonds in DNA.

Organization of the BcgI restriction-modification protein for the transfer of one methyl group to DNA.

Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics ⬇️

Phosphorylation decelerates conformational dynamics in bacterial translation elongation factors. ⬇️

Preprotein mature domains contain translocase targeting signals that are essential for secretion ⬇️

Protein complexes gain momentum.

Protomers of benzocaine: solvent and permittivity dependence

Proton Dynamics in Protein Mass Spectrometry. ⬇️

Quadrupole-time-of-flight mass spectrometer modified for higher-energy dissociation reduces protein assemblies to peptide fragments.

Radical solutions: Principles and application of electron-based dissociation in mass spectrometry-based analysis of protein structure ⬇️

Raman optical activity of human α -synuclein in intrinsically disordered, micelle-bound α -helical, molten globule and oligomeric β -sheet state ⬇️

Reactions of gold cluster cations Aun+ (n=1–12) with H2S and H2

Sample deposition onto cryo-EM grids: from sprays to jets and back

Signal loss due to oligomerization in ELISA analysis of amyloid-beta can be recovered by a novel sample pre-treatment method

Sizing up DNA nanostructure assembly with native mass spectrometry and ion mobility