Lista de obras - Jürgen Ruland - Dominio Público Uruguay

5'-Triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma

artículo científico publicado en 2008

A TSG101/MDM2 regulatory loop modulates MDM2 degradation and MDM2/p53 feedback control

artículo científico publicado en 2001

A homozygous mucosa-associated lymphoid tissue 1 (MALT1) mutation in a family with combined immunodeficiency

artículo científico publicado en 2013

A respiratory chain controlled signal transduction cascade in the mitochondrial intermembrane space mediates hydrogen peroxide signaling

artículo científico publicado en 2015

A systems-based intervention to promote smoking as a vital sign in patients served by community health centers.

artículo científico publicado en 2006

A8.25 CARD9 mediates autoantibody-induced autoimmune diseases by linking the SYK tyrosine kinase to CHEMOKINE production

Aberrant NF-kappaB signaling in lymphoma: mechanisms, consequences, and therapeutic implications

artículo científico publicado en 2007

Activation of the NLRP3 inflammasome byMycobacterium tuberculosisis uncoupled from susceptibility to active tuberculosis

scholarly article by Anca Dorhoi et al published 20 December 2011 in European Journal of Immunology

Adjuvanticity of a synthetic cord factor analogue for subunit Mycobacterium tuberculosis vaccination requires FcRgamma-Syk-Card9-dependent innate immune activation

artículo científico publicado en 2009

Akt is activated in response to an apoptotic signal.

artículo científico publicado en 2001

An innate antiviral pathway acting before interferons at epithelial surfaces

artículo científico publicado en 2015

B-cell expansion and lymphomagenesis induced by chronic CD40 signaling is strictly dependent on CD19.

artículo científico publicado en 2014

Bcl10 and Malt1 control lysophosphatidic acid-induced NF-kappaB activation and cytokine production

artículo científico publicado en 2006

Bcl10 links saturated fat overnutrition with hepatocellular NF-kB activation and insulin resistance

artículo científico publicado en 2012

Bcl10 mediates angiotensin II-induced cardiac damage and electrical remodeling

artículo científico publicado en 2014

Bcl10-controlled Malt1 paracaspase activity is key for the immune suppressive function of regulatory T cells

artículo científico publicado en 2019

Bimp1, a MAGUK family member linking protein kinase C activation to Bcl10-mediated NF-kappaB induction

artículo científico publicado en 2001

CARD-BCL-10-MALT1 signalling in protective and pathological immunity

artículo científico publicado en 2019

CARD9 signaling in the innate immune response

artículo científico publicado en 2008

CARMA3/Bcl10/MALT1-dependent NF-kappaB activation mediates angiotensin II-responsive inflammatory signaling in nonimmune cells

artículo científico publicado en 2007

Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity

scientific journal article

Card9-dependent IL-1β regulates IL-22 production from group 3 innate lymphoid cells and promotes colitis-associated cancer

artículo científico publicado en 2017

Caspase recruitment domain-containing protein 9 signaling in innate immunity and inflammation ⬇️

artículo científico publicado el 20 de marzo de 2013

Caspase-8 and c-FLIPL associate in lipid rafts with NF-kappaB adaptors during T cell activation.

artículo científico publicado en 2007

Caspase-8: Clipping off RIG-I Signaling ⬇️

artículo científico publicado el 25 de marzo de 2011

Cks1 is required for tumor cell proliferation but not sufficient to induce hematopoietic malignancies

artículo científico publicado en 2012

Clec12a is an inhibitory receptor for uric acid crystals that regulates inflammation in response to cell death

artículo científico publicado en 2014

Constitutive CD40 signaling in B cells selectively activates the noncanonical NF-kappaB pathway and promotes lymphomagenesis

artículo científico publicado en 2008

Cutting edge: Mincle is essential for recognition and adjuvanticity of the mycobacterial cord factor and its synthetic analog trehalose-dibehenate

artículo científico publicado en 2010

Decreased UDP-GlcNAc levels abrogate proliferation control in EMeg32-deficient cells.

artículo científico publicado en 2000

Decrypting drug actions and protein modifications by dose- and time-resolved proteomics

artículo científico publicado en 2023

Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection

artículo científico publicado en 2009

Dynamic landscape of pancreatic carcinogenesis reveals early molecular networks of malignancy

artículo científico publicado en 2016

Epigenomic Profiling of Human CD4(+) T Cells Supports a Linear Differentiation Model and Highlights Molecular Regulators of Memory Development

artículo científico publicado en 2016

Erratum: PD-1 is a haploinsufficient suppressor of T cell lymphomagenesis

artículo científico publicado en 2017

Essential role for IkappaB kinase beta in remodeling Carma1-Bcl10-Malt1 complexes upon T cell activation

artículo científico publicado en 2006

Experimental cerebral malaria develops independently of caspase recruitment domain-containing protein 9 signaling

artículo científico publicado en 2011

Foxp1 controls mature B cell survival and the development of follicular and B-1 B cells

artículo científico publicado en 2018

From virus to inflammation: Mechanisms of RIG-I-induced IL-1β production ⬇️

artículo científico publicado el 9 de abril de 2011

GP130 activation induces myeloma and collaborates with MYC.

artículo científico publicado en 2014

Guidelines for the use of flow cytometry and cell sorting in immunological studies

artículo científico publicado en 2017

Helicobacter pylori-induced IL-1β secretion in innate immune cells is regulated by the NLRP3 inflammasome and requires the cag pathogenicity island

artículo científico publicado en 2014

IKKα promotes intestinal tumorigenesis by limiting recruitment of M1-like polarized myeloid cells

artículo científico publicado en 2014

Immune sensing by activating and inhibitory C-type lectin receptors

Immunobiology of C-Type Lectin Receptors

Inflammatory signal transduction from the Fc epsilon RI to NF-kappa B.

artículo científico publicado en 2006

Interferon-β production via Dectin-1-Syk-IRF5 signaling in dendritic cells is crucial for immunity to C. albicans

artículo científico publicado en 2013

K+ Efflux-Independent NLRP3 Inflammasome Activation by Small Molecules Targeting Mitochondria

artículo científico publicado en 2016

MALT1 directs B cell receptor–induced canonical nuclear factor-κB signaling selectively to the c-Rel subunit

artículo científico publicado en 2007

MCL-1 gains occur with high frequency in lung adenocarcinoma and can be targeted therapeutically

scientific article published on 10 September 2020

Malt1 ubiquitination triggers NF-kappaB signaling upon T-cell activation

artículo científico publicado en 2007

Modified apoptotic molecule (BID) reduces hepatitis C virus infection in mice with chimeric human livers ⬇️

artículo científico publicado el 21 de abril de 2003

Mutations in the Histone Modifier PRDM6 Are Associated with Isolated Nonsyndromic Patent Ductus Arteriosus

artículo científico publicado en 2016

Oncogenic CARMA1 couples NF-κB and β-catenin signaling in diffuse large B-cell lymphomas.

artículo científico publicado en 2016

PD-1 is a haploinsufficient suppressor of T cell lymphomagenesis

artículo científico publicado en 2017

Pathogenic fungi regulate immunity by inducing neutrophilic myeloid-derived suppressor cells

artículo científico publicado en 2015

Perspectives from the front lines of tobacco control.

artículo científico publicado en 2006

Prdm6 is essential for cardiovascular development in vivo

artículo científico publicado en 2013

Protein kinase C-associated kinase (PKK) mediates Bcl10-independent NF-kappa B activation induced by phorbol ester

artículo científico publicado en 2002

RIG-I activation is critical for responsiveness to checkpoint blockade

artículo científico publicado en 2019

RIG-I detects infection with live Listeria by sensing secreted bacterial nucleic acids

artículo científico publicado en 2012

Rad50-CARD9 interactions link cytosolic DNA sensing to IL-1β production

artículo científico publicado en 2014

Re-activation of mitochondrial apoptosis inhibits T-cell lymphoma survival and treatment resistance

artículo científico publicado en 2016

Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production

artículo científico publicado en 2009

Restoration of pattern recognition receptor costimulation to treat chromoblastomycosis, a chronic fungal infection of the skin

artículo científico publicado en 2011

Return to homeostasis: downregulation of NF-κB responses ⬇️

artículo científico publicado el 19 de junio de 2011

Signaling crosstalk in DLBCL

scholarly article by Jürgen Ruland published 1 April 2008 in Blood

Somatic alterations compromised molecular diagnosis of DOCK8 hyper-IgE syndrome caused by a novel intronic splice site mutation

artículo científico publicado en 2018

Structural analysis of phenothiazine derivatives as allosteric inhibitors of the MALT1 paracaspase

artículo científico publicado en 2013

Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence

artículo científico publicado en 2009

Syk kinase-coupled C-type lectin receptors engage protein kinase C-σ to elicit Card9 adaptor-mediated innate immunity

scientific journal article

Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17

article by Salomé LeibundGut-Landmann et al published 22 April 2007 in Nature Immunology

TGF-β signalling is required for CD4⁺ T cell homeostasis but dispensable for regulatory T cell function

artículo científico publicado en 2013

The Bcl10-Malt1 complex segregates Fc epsilon RI-mediated nuclear factor kappa B activation and cytokine production from mast cell degranulation

scientific journal article

The CARD11-BCL10-MALT1 (CBM) signalosome complex: Stepping into the limelight of human primary immunodeficiency

artículo científico publicado en 2014

The NF-κB regulator MALT1 determines the encephalitogenic potential of Th17 cells

artículo científico publicado en 2012

The NF-κB signaling protein Bcl10 regulates actin dynamics by controlling AP1 and OCRL-bearing vesicles

artículo científico publicado en 2012

The Nlrp3 inflammasome regulates acute graft-versus-host disease

artículo científico publicado en 2013

The SYK tyrosine kinase: a crucial player in diverse biological functions

artículo científico publicado en 2010

The adaptor molecule CARD9 is essential for tuberculosis control

artículo científico publicado en 2010

The fungal peptide toxin Candidalysin activates the NLRP3 inflammasome and causes cytolysis in mononuclear phagocytes

artículo científico publicado en 2018

The mycobacterial cord factor adjuvant analogue trehalose-6,6′-dibehenate (TDB) activates the Nlrp3 inflammasome ⬇️

artículo científico publicado el 7 de agosto de 2012

The target landscape of clinical kinase drugs

artículo científico publicado en 2017

Tumor Necrosis Factor-Mediated Survival of CD169+ Cells Promotes Immune Activation during Vesicular Stomatitis Virus Infection

artículo científico publicado en 2017

Vav Proteins Are Key Regulators of Card9 Signaling for Innate Antifungal Immunity

artículo científico publicado en 2016

XIAP restricts TNF- and RIP3-dependent cell death and inflammasome activation

artículo científico publicado en 2014

p53 accumulation, defective cell proliferation, and early embryonic lethality in mice lacking tsg101.

artículo científico publicado en 2001

Lista de obras de Jürgen Ruland

5'-Triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma

A TSG101/MDM2 regulatory loop modulates MDM2 degradation and MDM2/p53 feedback control

A homozygous mucosa-associated lymphoid tissue 1 (MALT1) mutation in a family with combined immunodeficiency

A respiratory chain controlled signal transduction cascade in the mitochondrial intermembrane space mediates hydrogen peroxide signaling

A systems-based intervention to promote smoking as a vital sign in patients served by community health centers.

A8.25 CARD9 mediates autoantibody-induced autoimmune diseases by linking the SYK tyrosine kinase to CHEMOKINE production

Aberrant NF-kappaB signaling in lymphoma: mechanisms, consequences, and therapeutic implications

Activation of the NLRP3 inflammasome byMycobacterium tuberculosisis uncoupled from susceptibility to active tuberculosis

Adjuvanticity of a synthetic cord factor analogue for subunit Mycobacterium tuberculosis vaccination requires FcRgamma-Syk-Card9-dependent innate immune activation

Akt is activated in response to an apoptotic signal.

An innate antiviral pathway acting before interferons at epithelial surfaces

B-cell expansion and lymphomagenesis induced by chronic CD40 signaling is strictly dependent on CD19.

Bcl10 and Malt1 control lysophosphatidic acid-induced NF-kappaB activation and cytokine production

Bcl10 links saturated fat overnutrition with hepatocellular NF-kB activation and insulin resistance

Bcl10 mediates angiotensin II-induced cardiac damage and electrical remodeling

Bcl10-controlled Malt1 paracaspase activity is key for the immune suppressive function of regulatory T cells

Bimp1, a MAGUK family member linking protein kinase C activation to Bcl10-mediated NF-kappaB induction

CARD-BCL-10-MALT1 signalling in protective and pathological immunity

CARD9 signaling in the innate immune response

CARMA3/Bcl10/MALT1-dependent NF-kappaB activation mediates angiotensin II-responsive inflammatory signaling in nonimmune cells

Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity

Card9-dependent IL-1β regulates IL-22 production from group 3 innate lymphoid cells and promotes colitis-associated cancer

Caspase recruitment domain-containing protein 9 signaling in innate immunity and inflammation ⬇️

Caspase-8 and c-FLIPL associate in lipid rafts with NF-kappaB adaptors during T cell activation.

Caspase-8: Clipping off RIG-I Signaling ⬇️

Cks1 is required for tumor cell proliferation but not sufficient to induce hematopoietic malignancies

Clec12a is an inhibitory receptor for uric acid crystals that regulates inflammation in response to cell death

Constitutive CD40 signaling in B cells selectively activates the noncanonical NF-kappaB pathway and promotes lymphomagenesis

Cutting edge: Mincle is essential for recognition and adjuvanticity of the mycobacterial cord factor and its synthetic analog trehalose-dibehenate

Decreased UDP-GlcNAc levels abrogate proliferation control in EMeg32-deficient cells.

Decrypting drug actions and protein modifications by dose- and time-resolved proteomics

Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection

Dynamic landscape of pancreatic carcinogenesis reveals early molecular networks of malignancy

Epigenomic Profiling of Human CD4(+) T Cells Supports a Linear Differentiation Model and Highlights Molecular Regulators of Memory Development

Erratum: PD-1 is a haploinsufficient suppressor of T cell lymphomagenesis

Essential role for IkappaB kinase beta in remodeling Carma1-Bcl10-Malt1 complexes upon T cell activation

Experimental cerebral malaria develops independently of caspase recruitment domain-containing protein 9 signaling

Foxp1 controls mature B cell survival and the development of follicular and B-1 B cells

From virus to inflammation: Mechanisms of RIG-I-induced IL-1β production ⬇️

GP130 activation induces myeloma and collaborates with MYC.

Guidelines for the use of flow cytometry and cell sorting in immunological studies

Helicobacter pylori-induced IL-1β secretion in innate immune cells is regulated by the NLRP3 inflammasome and requires the cag pathogenicity island

IKKα promotes intestinal tumorigenesis by limiting recruitment of M1-like polarized myeloid cells

Immune sensing by activating and inhibitory C-type lectin receptors

Immunobiology of C-Type Lectin Receptors

Inflammatory signal transduction from the Fc epsilon RI to NF-kappa B.

Interferon-β production via Dectin-1-Syk-IRF5 signaling in dendritic cells is crucial for immunity to C. albicans

K+ Efflux-Independent NLRP3 Inflammasome Activation by Small Molecules Targeting Mitochondria

MALT1 directs B cell receptor–induced canonical nuclear factor-κB signaling selectively to the c-Rel subunit

MCL-1 gains occur with high frequency in lung adenocarcinoma and can be targeted therapeutically

Malt1 ubiquitination triggers NF-kappaB signaling upon T-cell activation

Modified apoptotic molecule (BID) reduces hepatitis C virus infection in mice with chimeric human livers ⬇️

Mutations in the Histone Modifier PRDM6 Are Associated with Isolated Nonsyndromic Patent Ductus Arteriosus

Oncogenic CARMA1 couples NF-κB and β-catenin signaling in diffuse large B-cell lymphomas.

PD-1 is a haploinsufficient suppressor of T cell lymphomagenesis

Pathogenic fungi regulate immunity by inducing neutrophilic myeloid-derived suppressor cells

Perspectives from the front lines of tobacco control.

Prdm6 is essential for cardiovascular development in vivo

Protein kinase C-associated kinase (PKK) mediates Bcl10-independent NF-kappa B activation induced by phorbol ester

RIG-I activation is critical for responsiveness to checkpoint blockade

RIG-I detects infection with live Listeria by sensing secreted bacterial nucleic acids

Rad50-CARD9 interactions link cytosolic DNA sensing to IL-1β production

Re-activation of mitochondrial apoptosis inhibits T-cell lymphoma survival and treatment resistance

Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production

Restoration of pattern recognition receptor costimulation to treat chromoblastomycosis, a chronic fungal infection of the skin

Return to homeostasis: downregulation of NF-κB responses ⬇️

Signaling crosstalk in DLBCL

Somatic alterations compromised molecular diagnosis of DOCK8 hyper-IgE syndrome caused by a novel intronic splice site mutation

Structural analysis of phenothiazine derivatives as allosteric inhibitors of the MALT1 paracaspase

Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence

Syk kinase-coupled C-type lectin receptors engage protein kinase C-σ to elicit Card9 adaptor-mediated innate immunity

Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17

TGF-β signalling is required for CD4⁺ T cell homeostasis but dispensable for regulatory T cell function

The Bcl10-Malt1 complex segregates Fc epsilon RI-mediated nuclear factor kappa B activation and cytokine production from mast cell degranulation

The CARD11-BCL10-MALT1 (CBM) signalosome complex: Stepping into the limelight of human primary immunodeficiency

The NF-κB regulator MALT1 determines the encephalitogenic potential of Th17 cells

The NF-κB signaling protein Bcl10 regulates actin dynamics by controlling AP1 and OCRL-bearing vesicles

The Nlrp3 inflammasome regulates acute graft-versus-host disease

The SYK tyrosine kinase: a crucial player in diverse biological functions