Lista de obras -

A unified genetic, computational and experimental framework identifies functionally relevant residues of the homing endonuclease I-BmoI.

artículo científico publicado en 2010

Activities and specificities of CRISPR/Cas9 and Cas12a nucleases for targeted mutagenesis in maize

artículo científico publicado en 2018

Allele-specific gene editing prevents deafness in a model of dominant progressive hearing loss

artículo científico publicado en 2019

Allele-specific silencing of the gain-of-function mutation in Huntington's disease using CRISPR-Cas9

artículo científico publicado en 2022

Author Correction: Broad-spectrum anti-CRISPR proteins facilitate horizontal gene transfer

scientific article published on 23 April 2020

Broad-spectrum anti-CRISPR proteins facilitate horizontal gene transfer

artículo científico publicado en 2020

Broadening the targeting range of Staphylococcus aureus CRISPR-Cas9 by modifying PAM recognition

artículo científico publicado en 2015

Camptothecin resistance is determined by the regulation of topoisomerase I degradation mediated by ubiquitin proteasome pathway.

artículo científico publicado en 2017

Cell-based artificial APC resistant to lentiviral transduction for efficient generation of CAR-T cells from various cell sources

artículo científico publicado en 2020

Discovery of widespread type I and type V CRISPR-Cas inhibitors

artículo científico publicado en 2018

Divalent metal ion differentially regulates the sequential nicking reactions of the GIY-YIG homing endonuclease I-BmoI.

artículo científico publicado en 2011

Engineered CRISPR-Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing

article

Engineered CRISPR-Cas9 nucleases with altered PAM specificities

artículo científico publicado en 2015

Enhanced proofreading governs CRISPR-Cas9 targeting accuracy

artículo científico publicado en 2017

Estimating the evidence of selection and the reliability of inference in unigenic evolution.

artículo científico publicado en 2010

Genome editing in animals with minimal PAM CRISPR-Cas9 enzymes

artículo científico publicado en 2022

Genome-wide specificities of CRISPR-Cas Cpf1 nucleases in human cells.

artículo científico publicado en 2016

High levels of AAV vector integration into CRISPR-induced DNA breaks

scientific article published on 30 September 2019

High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects.

artículo científico publicado en 2016

Hypoxia drives transient site-specific copy gain and drug-resistant gene expression.

artículo científico publicado en 2015

In vivo engineering of lymphocytes after systemic exosome-associated AAV delivery

scientific article published on 11 March 2020

Inducible and multiplex gene regulation using CRISPR-Cpf1-based transcription factors.

artículo científico publicado en 2017

Isocitrate Dehydrogenase Mutations Confer Dasatinib Hypersensitivity and SRC Dependence in Intrahepatic Cholangiocarcinoma

artículo científico publicado en 2016

Monomeric site-specific nucleases for genome editing ⬇️

artículo científico publicado el 7 de mayo de 2012

Optimization of AsCas12a for combinatorial genetic screens in human cells

artículo científico publicado en 2020

Prediction of off-target activities for the end-to-end design of CRISPR guide RNAs

artículo científico publicado en 2018

Publisher Correction: Engineered CRISPR-Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing

artículo científico publicado en 2020

Rapid screening of endonuclease target site preference using a modified bacterial two-plasmid selection

artículo científico publicado en 2014

Scalable characterization of the PAM requirements of CRISPR-Cas enzymes using HT-PAMDA

artículo científico publicado en 2021

Strand-specific contacts and divalent metal ion regulate double-strand break formation by the GIY-YIG homing endonuclease I-BmoI

artículo científico publicado en 2007

Temporal and Spatial Post-Transcriptional Regulation of Zebrafish Tie1 mRNA by Long Noncoding RNA During Brain Vascular Assembly.

artículo científico publicado en 2018

The I-TevI nuclease and linker domains contribute to the specificity of monomeric TALENs

artículo científico publicado en 2014

The monomeric GIY-YIG homing endonuclease I-BmoI uses a molecular anchor and a flexible tether to sequentially nick DNA.

artículo científico publicado en 2013

Unconstrained genome targeting with near-PAMless engineered CRISPR-Cas9 variants

artículo científico publicado en 2020

Voices in methods development

artículo científico publicado en 2019

Lista de obras de

A unified genetic, computational and experimental framework identifies functionally relevant residues of the homing endonuclease I-BmoI.

Activities and specificities of CRISPR/Cas9 and Cas12a nucleases for targeted mutagenesis in maize

Allele-specific gene editing prevents deafness in a model of dominant progressive hearing loss

Allele-specific silencing of the gain-of-function mutation in Huntington's disease using CRISPR-Cas9

Author Correction: Broad-spectrum anti-CRISPR proteins facilitate horizontal gene transfer

Broad-spectrum anti-CRISPR proteins facilitate horizontal gene transfer

Broadening the targeting range of Staphylococcus aureus CRISPR-Cas9 by modifying PAM recognition

Camptothecin resistance is determined by the regulation of topoisomerase I degradation mediated by ubiquitin proteasome pathway.

Cell-based artificial APC resistant to lentiviral transduction for efficient generation of CAR-T cells from various cell sources

Discovery of widespread type I and type V CRISPR-Cas inhibitors

Divalent metal ion differentially regulates the sequential nicking reactions of the GIY-YIG homing endonuclease I-BmoI.

Engineered CRISPR-Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing

Engineered CRISPR-Cas9 nucleases with altered PAM specificities

Enhanced proofreading governs CRISPR-Cas9 targeting accuracy

Estimating the evidence of selection and the reliability of inference in unigenic evolution.

Genome editing in animals with minimal PAM CRISPR-Cas9 enzymes

Genome-wide specificities of CRISPR-Cas Cpf1 nucleases in human cells.

High levels of AAV vector integration into CRISPR-induced DNA breaks

High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects.

Hypoxia drives transient site-specific copy gain and drug-resistant gene expression.

In vivo engineering of lymphocytes after systemic exosome-associated AAV delivery

Inducible and multiplex gene regulation using CRISPR-Cpf1-based transcription factors.

Isocitrate Dehydrogenase Mutations Confer Dasatinib Hypersensitivity and SRC Dependence in Intrahepatic Cholangiocarcinoma

Monomeric site-specific nucleases for genome editing ⬇️

Optimization of AsCas12a for combinatorial genetic screens in human cells

Prediction of off-target activities for the end-to-end design of CRISPR guide RNAs

Publisher Correction: Engineered CRISPR-Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing

Rapid screening of endonuclease target site preference using a modified bacterial two-plasmid selection

Scalable characterization of the PAM requirements of CRISPR-Cas enzymes using HT-PAMDA

Strand-specific contacts and divalent metal ion regulate double-strand break formation by the GIY-YIG homing endonuclease I-BmoI

Temporal and Spatial Post-Transcriptional Regulation of Zebrafish Tie1 mRNA by Long Noncoding RNA During Brain Vascular Assembly.

The I-TevI nuclease and linker domains contribute to the specificity of monomeric TALENs

The monomeric GIY-YIG homing endonuclease I-BmoI uses a molecular anchor and a flexible tether to sequentially nick DNA.

Unconstrained genome targeting with near-PAMless engineered CRISPR-Cas9 variants

Voices in methods development

Whole-genome sequencing association analysis of quantitative red blood cell phenotypes: The NHLBI TOPMed program