Lista de obras -

A brief overview of the 32nd Annual STP Symposium on the Toxicologic Pathology of the Digestive Tract and Pancreas

artículo científico publicado en 2013

A brief overview of the 32nd Annual STP Symposium on the Toxicologic Pathology of the Digestive Tract and Pancreas.

artículo científico publicado en 2014

A humanized monoclonal antibody targeting the β7 integrin selectively blocks intestinal homing of T lymphocytes ⬇️

artículo científico publicado el 1 de abril de 2011

A randomised phase I study of etrolizumab (rhuMAb β7) in moderate to severe ulcerative colitis ⬇️

artículo científico publicado el 20 de junio de 2012

A soluble BAFF antagonist, BR3-Fc, decreases peripheral blood B cells and lymphoid tissue marginal zone and follicular B cells in cynomolgus monkeys

artículo científico publicado en 2006

Actin-bundling protein L-plastin regulates T cell activation.

artículo científico publicado en 2010

An Overview of the Pathogenesis of Immune-mediated Skin Injury.

artículo científico publicado en 2016

Anti-BR3 antibodies: a new class of B-cell immunotherapy combining cellular depletion and survival blockade

artículo científico publicado en 2007

Anti-CD22 and anti-CD79b antibody-drug conjugates preferentially target proliferating B cells

artículo científico publicado en 2016

B-cell activation influences T-cell polarization and outcome of anti-CD20 B-cell depletion in central nervous system autoimmunity

artículo científico publicado en 2010

Canine leukocyte cell adhesion molecules (LeuCAMs): characterization of the CD11/CD18 family

artículo científico publicado el 1 de julio de 1992

Canine leukocyte integrins: Characterization of a CD 18 homologue ⬇️

artículo científico publicado el 1 de noviembre de 1990

Combined treatment of acute EAE in Lewis rats with TNF-binding protein and interleukin-1 receptor antagonist.

artículo científico publicado en 1998

DCDT2980S, an anti-CD22-monomethyl auristatin E antibody-drug conjugate, is a potential treatment for non-Hodgkin lymphoma

artículo científico publicado en 2013

Effect of recombinant human keratinocyte growth factor (rHuKGF) on the immunopathogenesis of intestinal graft-vs.-host disease induced without a preconditioning regimen.

artículo científico publicado en 2004

Evidence for an asialoglycoprotein receptor on nonparenchymal cells for O-linked glycoproteins

scientific article published on 26 August 2008

FGF-18, a Novel Member of the Fibroblast Growth Factor Family, Stimulates Hepatic and Intestinal Proliferation ⬇️

artículo científico publicado el 1 de octubre de 1998

Fgf-10 is required for both limb and lung development and exhibits striking functional similarity to Drosophila branchless

scientific journal article

Genetic deletion of JAM-C reveals a role in myeloid progenitor generation

scientific journal article

Growth factors in porcine full and partial thickness burn repair. Differing targets and effects of keratinocyte growth factor, platelet-derived growth factor-BB, epidermal growth factor, and neu differentiation factor.

artículo científico publicado en 1995

IL-17RC is required for IL-17A- and IL-17F-dependent signaling and the pathogenesis of experimental autoimmune encephalomyelitis.

artículo científico publicado en 2010

IL-22R Ligands IL-20, IL-22, and IL-24 Promote Wound Healing in Diabetic db/db Mice

artículo científico publicado en 2017

In Vitro Skin Models and Their Predictability in Defining Normal and Disease Biology, Pharmacology, and Toxicity

artículo científico publicado en 2016

Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens

artículo científico publicado en 2008

Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis

artículo científico publicado en 2007

Investigation of epidermotropism in canine mycosis fungoides: expression of intercellular adhesion molecule-1 (ICAM-1) and beta-2 integrins.

artículo científico publicado en 1995

Keratinocyte Growth Factor Causes Proliferation of Urothelium In Vivo ⬇️

artículo científico publicado el 1 de octubre de 1995

Keratinocyte growth factor is an important endogenous mediator of hair follicle growth, development, and differentiation. Normalization of the nu/nu follicular differentiation defect and amelioration of chemotherapy-induced alopecia ⬇️

artículo científico publicado el 1 de julio de 1995

Keratinocyte growth factor preserves normal thymopoiesis and thymic microenvironment during experimental graft-versus-host disease

scientific article published on 01 July 2002

Long-term impaired neutrophil migration in mice overexpressing human interleukin-8 ⬇️

artículo científico publicado el 1 de septiembre de 1994

Minipig as a potential translatable model for monoclonal antibody pharmacokinetics after intravenous and subcutaneous administration.

artículo científico publicado en 2012

Monoclonal antibodies specific for canine CD4 and CD8 define functional T-lymphocyte subsets and high-density expression of CD4 by canine neutrophils

artículo científico publicado el 1 de agosto de 1992

Neu differentiation factor upregulates epidermal migration and integrin expression in excisional wounds.

artículo científico publicado en 1995

New strategies for the prevention of radiation injury: possible implications for countering radiation hazards of long-term space travel.

artículo científico publicado en 2002

Nonclinical safety assessment of a human interleukin-22FC IG fusion protein demonstrates in vitro to in vivo and cross-species translatability

artículo científico publicado en 2018

Nonselective inhibition of the epigenetic transcriptional regulator BET induces marked lymphoid and hematopoietic toxicity in mice.

artículo científico publicado en 2016

Pharmacokinetics, pharmacodynamics, and safety assessment of palifermin (rHuKGF) in healthy volunteers

scientific article published on 01 June 2006

Polar solvents decrease the viscosity of high concentration IgG1 solutions through hydrophobic solvation and interaction: formulation and biocompatibility considerations.

artículo científico publicado en 2013

Pre-clinical and translational pharmacology of a human interleukin-22 IgG fusion protein for potential treatment of infectious or inflammatory diseases

artículo científico publicado en 2018

Preclinical Safety Profile of a Depleting Antibody against CRTh2 for Asthma: Well Tolerated Despite Unexpected CRTh2 Expression on Vascular Pericytes in the Central Nervous System and Gastric Mucosa.

artículo científico publicado en 2016

Proliferative and non-proliferative lesions of the rat and mouse integument.

artículo científico publicado en 2013

Protection from thymic epithelial cell injury by keratinocyte growth factor: a new approach to improve thymic and peripheral T-cell reconstitution after bone marrow transplantation

artículo científico publicado en 2002

Randomized Phase I Healthy Volunteer Study of UTTR1147A (IL-22Fc): A Potential Therapy for Epithelial Injury

artículo científico publicado en 2018

Recombinant rat fibroblast growth factor-16: structure and biological activity.

artículo científico publicado en 1999

Requirement for coronin 1 in T lymphocyte trafficking and cellular homeostasis

scientific journal article

Review article: nonclinical and clinical pharmacology, pharmacokinetics and pharmacodynamics of etrolizumab, an anti-β7 integrin therapy for inflammatory bowel disease.

artículo científico publicado en 2018

Stimulation of all epithelial elements during skin regeneration by keratinocyte growth factor.

artículo científico publicado en 1994

TWEAK attenuates the transition from innate to adaptive immunity

artículo científico publicado en 2005

The Effects of IL-20 Subfamily Cytokines on Reconstituted Human Epidermis Suggest Potential Roles in Cutaneous Innate Defense and Pathogenic Adaptive Immunity in Psoriasis

artículo científico publicado en 2007

The Yin and Yang of Immunomodulatory Biologics: Assessing the Delicate Balance between Benefit and Risk ⬇️

artículo científico publicado el 5 de enero de 2012

The tsA58 simian virus 40 large tumor antigen disrupts megakaryocyte differentiation in transgenic mice.

artículo científico publicado en 1994

Therapeutic Antibody-Induced Vascular Toxicity Due to Off-Target Activation of Nitric Oxide in Cynomolgus Monkeys.

artículo científico publicado en 2016

Lista de obras de

A brief overview of the 32nd Annual STP Symposium on the Toxicologic Pathology of the Digestive Tract and Pancreas

A brief overview of the 32nd Annual STP Symposium on the Toxicologic Pathology of the Digestive Tract and Pancreas.

A humanized monoclonal antibody targeting the β7 integrin selectively blocks intestinal homing of T lymphocytes ⬇️

A randomised phase I study of etrolizumab (rhuMAb β7) in moderate to severe ulcerative colitis ⬇️

A soluble BAFF antagonist, BR3-Fc, decreases peripheral blood B cells and lymphoid tissue marginal zone and follicular B cells in cynomolgus monkeys

Actin-bundling protein L-plastin regulates T cell activation.

An Overview of the Pathogenesis of Immune-mediated Skin Injury.

Anti-BR3 antibodies: a new class of B-cell immunotherapy combining cellular depletion and survival blockade

Anti-CD22 and anti-CD79b antibody-drug conjugates preferentially target proliferating B cells

B-cell activation influences T-cell polarization and outcome of anti-CD20 B-cell depletion in central nervous system autoimmunity

Canine leukocyte cell adhesion molecules (LeuCAMs): characterization of the CD11/CD18 family

Canine leukocyte integrins: Characterization of a CD 18 homologue ⬇️

Combined treatment of acute EAE in Lewis rats with TNF-binding protein and interleukin-1 receptor antagonist.

DCDT2980S, an anti-CD22-monomethyl auristatin E antibody-drug conjugate, is a potential treatment for non-Hodgkin lymphoma

Effect of recombinant human keratinocyte growth factor (rHuKGF) on the immunopathogenesis of intestinal graft-vs.-host disease induced without a preconditioning regimen.

Evidence for an asialoglycoprotein receptor on nonparenchymal cells for O-linked glycoproteins

FGF-18, a Novel Member of the Fibroblast Growth Factor Family, Stimulates Hepatic and Intestinal Proliferation ⬇️

Fgf-10 is required for both limb and lung development and exhibits striking functional similarity to Drosophila branchless

Genetic deletion of JAM-C reveals a role in myeloid progenitor generation

Growth factors in porcine full and partial thickness burn repair. Differing targets and effects of keratinocyte growth factor, platelet-derived growth factor-BB, epidermal growth factor, and neu differentiation factor.

IL-17RC is required for IL-17A- and IL-17F-dependent signaling and the pathogenesis of experimental autoimmune encephalomyelitis.

IL-22R Ligands IL-20, IL-22, and IL-24 Promote Wound Healing in Diabetic db/db Mice

In Vitro Skin Models and Their Predictability in Defining Normal and Disease Biology, Pharmacology, and Toxicity

Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens

Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis

Investigation of epidermotropism in canine mycosis fungoides: expression of intercellular adhesion molecule-1 (ICAM-1) and beta-2 integrins.

Keratinocyte Growth Factor Causes Proliferation of Urothelium In Vivo ⬇️

Keratinocyte growth factor is an important endogenous mediator of hair follicle growth, development, and differentiation. Normalization of the nu/nu follicular differentiation defect and amelioration of chemotherapy-induced alopecia ⬇️

Keratinocyte growth factor preserves normal thymopoiesis and thymic microenvironment during experimental graft-versus-host disease

Long-term impaired neutrophil migration in mice overexpressing human interleukin-8 ⬇️

Minipig as a potential translatable model for monoclonal antibody pharmacokinetics after intravenous and subcutaneous administration.

Monoclonal antibodies specific for canine CD4 and CD8 define functional T-lymphocyte subsets and high-density expression of CD4 by canine neutrophils

Neu differentiation factor upregulates epidermal migration and integrin expression in excisional wounds.

New strategies for the prevention of radiation injury: possible implications for countering radiation hazards of long-term space travel.

Nonclinical safety assessment of a human interleukin-22FC IG fusion protein demonstrates in vitro to in vivo and cross-species translatability

Nonselective inhibition of the epigenetic transcriptional regulator BET induces marked lymphoid and hematopoietic toxicity in mice.

Pharmacokinetics, pharmacodynamics, and safety assessment of palifermin (rHuKGF) in healthy volunteers

Polar solvents decrease the viscosity of high concentration IgG1 solutions through hydrophobic solvation and interaction: formulation and biocompatibility considerations.

Pre-clinical and translational pharmacology of a human interleukin-22 IgG fusion protein for potential treatment of infectious or inflammatory diseases

Preclinical Safety Profile of a Depleting Antibody against CRTh2 for Asthma: Well Tolerated Despite Unexpected CRTh2 Expression on Vascular Pericytes in the Central Nervous System and Gastric Mucosa.

Proliferative and non-proliferative lesions of the rat and mouse integument.

Protection from thymic epithelial cell injury by keratinocyte growth factor: a new approach to improve thymic and peripheral T-cell reconstitution after bone marrow transplantation

Randomized Phase I Healthy Volunteer Study of UTTR1147A (IL-22Fc): A Potential Therapy for Epithelial Injury

Recombinant rat fibroblast growth factor-16: structure and biological activity.

Requirement for coronin 1 in T lymphocyte trafficking and cellular homeostasis

Review article: nonclinical and clinical pharmacology, pharmacokinetics and pharmacodynamics of etrolizumab, an anti-β7 integrin therapy for inflammatory bowel disease.

Stimulation of all epithelial elements during skin regeneration by keratinocyte growth factor.

TWEAK attenuates the transition from innate to adaptive immunity

The Effects of IL-20 Subfamily Cytokines on Reconstituted Human Epidermis Suggest Potential Roles in Cutaneous Innate Defense and Pathogenic Adaptive Immunity in Psoriasis

The Yin and Yang of Immunomodulatory Biologics: Assessing the Delicate Balance between Benefit and Risk ⬇️

The tsA58 simian virus 40 large tumor antigen disrupts megakaryocyte differentiation in transgenic mice.

Therapeutic Antibody-Induced Vascular Toxicity Due to Off-Target Activation of Nitric Oxide in Cynomolgus Monkeys.