Lista de obras - Connie Jackaman - Dominio Público Uruguay

Actin nemaline myopathy mouse reproduces disease, suggests other actin disease phenotypes and provides cautionary note on muscle transgene expression

artículo científico publicado en 2011

Aged neutrophils accumulate in lymphoid tissues from healthy elderly mice and infiltrate T and B cell zones

artículo científico publicado en 2018

Aging and cancer: The role of macrophages and neutrophils.

artículo científico publicado en 2017

Are macrophages, myeloid derived suppressor cells and neutrophils mediators of local suppression in healthy and cancerous tissues in aging hosts?

artículo científico publicado en 2013

Blood-brain barrier dysfunction developed during normal aging is associated with inflammation and loss of tight junctions but not with leukocyte recruitment.

artículo científico publicado en 2015

CD40-activated B cells contribute to mesothelioma tumor regression.

artículo científico publicado en 2010

CD8 cytotoxic T cell responses to dominant tumor-associated antigens are profoundly weakened by aging yet subdominant responses retain functionality and expand in response to chemotherapy

article

Chemotherapy broadens the range of tumor antigens seen by cytotoxic CD8(+) T cells in vivo.

artículo científico publicado en 2012

Deliberately provoking local inflammation drives tumors to become their own protective vaccine site.

artículo científico publicado en 2008

Dissociated flexor digitorum brevis myofiber culture system--a more mature muscle culture system.

artículo científico publicado en 2007

Elderly dendritic cells respond to LPS/IFN-γ and CD40L stimulation despite incomplete maturation.

artículo científico publicado en 2018

Ex vivo expression of chemokine receptors on cells surrounding cutaneous nerves in patients with HIV-associated sensory neuropathy

artículo científico publicado en 2017

Functional endogenous cytotoxic T lymphocytes are generated to multiple antigens co-expressed by progressing tumors; after intra-tumoral IL-2 therapy these effector cells eradicate established tumors

artículo científico publicado en 2005

IL-2 intratumoral immunotherapy enhances CD8+ T cells that mediate destruction of tumor cells and tumor-associated vasculature: a novel mechanism for IL-2.

artículo científico publicado en 2003

IL-2/CD40-activated macrophages rescue age and tumor-induced T cell dysfunction in elderly mice.

artículo científico publicado en 2014

Intratumoral interleukin-2/agonist CD40 antibody drives CD4+-independent resolution of treated-tumors and CD4+-dependent systemic and memory responses ⬇️

artículo científico publicado el 15 de octubre de 2011

Intratumoral poly-N-acetyl glucosamine-based polymer matrix provokes a prolonged local inflammatory response that, when combined with IL-2, induces regression of malignant mesothelioma in a murine model.

artículo científico publicado en 2005

Lipid-laden partially-activated plasmacytoid and CD4(-)CD8α(+) dendritic cells accumulate in tissues in elderly mice

artículo científico publicado en 2014

Local effector failure in mesothelioma is not mediated by CD4+ CD25+ T-regulator cells.

artículo científico publicado en 2009

Macrophage Depletion in Elderly Mice Improves Response to Tumor Immunotherapy, Increases Anti-tumor T Cell Activity and Reduces Treatment-Induced Cachexia

artículo científico publicado en 2018

Mesothelioma tumor cells modulate dendritic cell lipid content, phenotype and function

artículo científico publicado en 2015

Modulation of dendritic cell and T cell cross-talk during aging: The potential role of checkpoint inhibitory molecules.

artículo científico publicado en 2017

Mouse models of dominant ACTA1 disease recapitulate human disease and provide insight into therapies

artículo científico publicado en 2011

Multiple Osmotic Stress Responses in Acidihalobacter prosperus Result in Tolerance to Chloride Ions.

artículo científico publicado en 2016

Murine mesothelioma induces locally-proliferating IL-10(+)TNF-α(+)CD206(-)CX3CR1(+) M3 macrophages that can be selectively depleted by chemotherapy or immunotherapy

artículo científico publicado en 2016

Novel application of flow cytometry: determination of muscle fiber types and protein levels in whole murine skeletal muscles and heart

artículo científico publicado en 2007

Rapid copper acquisition by developing murine mesothelioma: decreasing bioavailable copper slows tumor growth, normalizes vessels and promotes T cell infiltration

artículo científico publicado en 2013

Rescue of skeletal muscle alpha-actin-null mice by cardiac (fetal) alpha-actin

artículo científico publicado en 2009

Targeting macrophages rescues age-related immune deficiencies in C57BL/6J geriatric mice.

artículo científico publicado en 2013

The Regulatory Status Adopted by Lymph Node Dendritic Cells and T Cells During Healthy Aging Is Maintained During Cancer and May Contribute to Reduced Responses to Immunotherapy

article

Lista de obras de Connie Jackaman

Actin nemaline myopathy mouse reproduces disease, suggests other actin disease phenotypes and provides cautionary note on muscle transgene expression

Aged neutrophils accumulate in lymphoid tissues from healthy elderly mice and infiltrate T and B cell zones

Aging and cancer: The role of macrophages and neutrophils.

Are macrophages, myeloid derived suppressor cells and neutrophils mediators of local suppression in healthy and cancerous tissues in aging hosts?

Blood-brain barrier dysfunction developed during normal aging is associated with inflammation and loss of tight junctions but not with leukocyte recruitment.

CD40-activated B cells contribute to mesothelioma tumor regression.

CD8 cytotoxic T cell responses to dominant tumor-associated antigens are profoundly weakened by aging yet subdominant responses retain functionality and expand in response to chemotherapy

Chemotherapy broadens the range of tumor antigens seen by cytotoxic CD8(+) T cells in vivo.

Deliberately provoking local inflammation drives tumors to become their own protective vaccine site.

Dissociated flexor digitorum brevis myofiber culture system--a more mature muscle culture system.

Elderly dendritic cells respond to LPS/IFN-γ and CD40L stimulation despite incomplete maturation.

Ex vivo expression of chemokine receptors on cells surrounding cutaneous nerves in patients with HIV-associated sensory neuropathy

Functional endogenous cytotoxic T lymphocytes are generated to multiple antigens co-expressed by progressing tumors; after intra-tumoral IL-2 therapy these effector cells eradicate established tumors

IL-2 intratumoral immunotherapy enhances CD8+ T cells that mediate destruction of tumor cells and tumor-associated vasculature: a novel mechanism for IL-2.

IL-2/CD40-activated macrophages rescue age and tumor-induced T cell dysfunction in elderly mice.

Intratumoral interleukin-2/agonist CD40 antibody drives CD4+-independent resolution of treated-tumors and CD4+-dependent systemic and memory responses ⬇️

Intratumoral poly-N-acetyl glucosamine-based polymer matrix provokes a prolonged local inflammatory response that, when combined with IL-2, induces regression of malignant mesothelioma in a murine model.

Lipid-laden partially-activated plasmacytoid and CD4(-)CD8α(+) dendritic cells accumulate in tissues in elderly mice

Local effector failure in mesothelioma is not mediated by CD4+ CD25+ T-regulator cells.

Macrophage Depletion in Elderly Mice Improves Response to Tumor Immunotherapy, Increases Anti-tumor T Cell Activity and Reduces Treatment-Induced Cachexia

Mesothelioma tumor cells modulate dendritic cell lipid content, phenotype and function

Modulation of dendritic cell and T cell cross-talk during aging: The potential role of checkpoint inhibitory molecules.

Mouse models of dominant ACTA1 disease recapitulate human disease and provide insight into therapies

Multiple Osmotic Stress Responses in Acidihalobacter prosperus Result in Tolerance to Chloride Ions.

Murine mesothelioma induces locally-proliferating IL-10(+)TNF-α(+)CD206(-)CX3CR1(+) M3 macrophages that can be selectively depleted by chemotherapy or immunotherapy

Novel application of flow cytometry: determination of muscle fiber types and protein levels in whole murine skeletal muscles and heart

Rapid copper acquisition by developing murine mesothelioma: decreasing bioavailable copper slows tumor growth, normalizes vessels and promotes T cell infiltration

Rescue of skeletal muscle alpha-actin-null mice by cardiac (fetal) alpha-actin

Targeting macrophages rescues age-related immune deficiencies in C57BL/6J geriatric mice.

The Regulatory Status Adopted by Lymph Node Dendritic Cells and T Cells During Healthy Aging Is Maintained During Cancer and May Contribute to Reduced Responses to Immunotherapy