Lista de obras - Paolo Ubezio - Dominio Público Uruguay

A biodistribution study of PEGylated PCL-based nanoparticles in C57BL/6 mice bearing B16/F10 melanoma.

artículo científico publicado en 2014

A generalised age- and phase-structured model of human tumour cell populations both unperturbed and exposed to a range of cancer therapies.

artículo científico publicado en 2007

A mathematical model of the effect of aging on bone marrow cells colonizing the thymus.

artículo científico publicado en 1993

A methyl methacrylate-HEMA-CL(n) copolymerization investigation: from kinetics to bioapplications.

artículo científico publicado en 2013

A specific miRNA signature correlates with complete pathological response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer.

artículo científico publicado en 2011

ActivinA: a new leukemia-promoting factor conferring migratory advantage to B-cell precursor-acute lymphoblastic leukemic cells

artículo científico publicado en 2018

Anthracycline resistance: cytofluorometric study on infantile lymphoblastic leukemia

artículo científico publicado en 1989

Application of 3D Mass Spectrometry Imaging to TKIs

artículo científico publicado en 2017

Beyond The T/C Ratio: Old And New Anticancer Activity Scores In Vivo

scientific article published on 19 September 2019

Biochemical, morphological and flow-cytometric evaluation of the effects of hexachlorobenzene on rat liver

scientific article published on 01 April 1990

Calpain as a multi-site regulator of cell cycle.

artículo científico publicado en 2004

Cediranib combined with chemotherapy reduces tumor dissemination and prolongs the survival of mice bearing patient-derived ovarian cancer xenografts with different responsiveness to cisplatin

artículo científico publicado en 2015

Cell cycle simulation for flow cytometry.

artículo científico publicado en 1990

Cell killing and resistance in pre-operative breast cancer chemotherapy

artículo científico publicado en 2008

Cell kinetics of human ovarian cancer with in vivo administration of bromodeoxyuridine

artículo científico publicado en 1994

Cell loss and the concept of potential doubling time ⬇️

artículo científico publicado el 1 de septiembre de 1997

Cellular and molecular determinants of all-trans retinoic acid sensitivity in breast cancer: Luminal phenotype and RARα expression

artículo científico publicado en 2015

Characterization of cyclin B1 expression in human cancer cell lines by a new three-parameter BrdUrd/cyclin B1/DNA analysis

scientific article published on 01 January 1998

Combination of PPARγ Agonist Pioglitazone and Trabectedin Induce Adipocyte Differentiation to Overcome Trabectedin Resistance in Myxoid Liposarcomas

artículo científico publicado en 2019

Combination of the new minor groove alkylator tallimustine and melphalan

artículo científico publicado en 1997

Combination of trabectedin and irinotecan is highly effective in a human rhabdomyosarcoma xenograft

artículo científico publicado en 2005

Comparison of histone variant synthesis in human lymphocytic leukemia cells and in normal lymphocytes

artículo científico publicado en 1988

Cytologic and flow cytometric DNA analysis of multinucleated tumor cells and derived microcells

artículo científico publicado en 1989

DNA damage, cytotoxic effect and cell-cycle perturbation of Hoechst 33342 on L1210 cells in vitro ⬇️

artículo científico publicado el 1 de enero de 1988

Doxorubicin and m-AMSA induced DNA damage in blast cells from AML patients

artículo científico publicado en 1991

Dynamic rendering of the heterogeneous cell response to anticancer treatments

artículo científico publicado en 2013

Dynamics of cell cycle phase perturbations by trabectedin (ET-743) in nucleotide excision repair (NER)-deficient and NER-proficient cells, unravelled by a novel mathematical simulation approach.

artículo científico publicado en 2007

Effective combination of ET-743 and doxorubicin in sarcoma: preclinical studies

artículo científico publicado en 2003

Enhanced cell cycle perturbation and apoptosis mediate the synergistic effects of ST1926 and ATRA in neuroblastoma preclinical models

artículo científico publicado en 2011

Fate of PLA and PCL-Based Polymeric Nanocarriers in Cellular and Animal Models of Triple-Negative Breast Cancer.

artículo científico publicado en 2016

Flow-cytometric analysis of DNA distribution after VP16-213 treatment of Lewis lung carcinoma

scientific article published on 01 January 1983

From flow cytometric BrdUrd data to cell population growth and doubling time ⬇️

artículo científico publicado el 1 de noviembre de 1997

Genotoxic damage induced by doxorubicin in two human melanoma cell lines

artículo científico publicado en 1987

HER2-positive breast-cancer cell lines are sensitive to KDM5 inhibition: definition of a gene-expression model for the selection of sensitive cases

artículo científico publicado en 2018

Heterogeneous cell response to topotecan in a CFSE-based proliferation test.

artículo científico publicado en 2004

Histone H1(0) is synthesized by human lymphocytic leukemia cells but not by normal lymphocytes

artículo científico publicado en 1987

In vivo measurement of vascular modulation in experimental tumors using a fluorescent contrast agent

artículo científico publicado en 2008

Increasing 1-beta-D-arabinofuranosylcytosine efficacy by scheduled dosing intervals based on direct measurements of bone marrow cell kinetics

artículo científico publicado en 1994

Inhibition of SIRT2 potentiates the anti-motility activity of taxanes: implications for antineoplastic combination therapies.

artículo científico publicado en 2012

Integrated experimental and simulation study of the response to sequential treatment with erlotinib and gemcitabine in pancreatic cancer.

artículo científico publicado en 2016

Integrated multiplatform method for in vitro quantitative assessment of cellular uptake for fluorescent polymer nanoparticles.

artículo científico publicado en 2014

Interoperability of time series cytometric data: a cross platform approach for modeling tumor heterogeneity.

artículo científico publicado en 2011

Interpreting cell cycle effects of drugs: the case of melphalan.

artículo científico publicado en 2005

Intracellular doxorubicin concentrations and drug-induced DNA damage in a human colon adenocarcinoma cell line and in a drug-resistant subline.

artículo científico publicado en 1988

Intracellular drug concentration and DNA damage in human childhood leukemic cells exposed to doxorubicin

artículo científico publicado en 1988

Intracellular glutathione heterogeneity in L1210 murine leukemia sublines made resistant to DNA-interacting anti-neoplastic agents.

artículo científico publicado en 1993

Kinetic heterogeneity of an experimental tumour revealed by BrdUrd incorporation and mathematical modelling.

artículo científico publicado en 2002

Measuring the complexity of cell cycle arrest and killing of drugs: kinetics of phase-specific effects induced by taxol

scientific article published on 01 October 1999

Microcomputer experience in analysis of flow cytometric DNA distributions

scientific article published on 01 January 1985

Miniaturizing bromodeoxyuridine incorporation enables the usage of flow cytometry for cell cycle analysis of adherent tissue culture cells for high throughput screening.

artículo científico publicado en 2010

Modeling Cytostatic and Cytotoxic Responses to New Treatment Regimens for Ovarian Cancer

artículo científico publicado en 2017

Modeling of non-small cell lung cancer volume changes during CT-based image guided radiotherapy: patterns observed and clinical implications

artículo científico publicado en 2013

Modelling the balance between quiescence and cell death in normal and tumour cell populations.

artículo científico publicado en 2006

PEGylated Nanoparticles Obtained through Emulsion Polymerization as Paclitaxel Carriers

artículo científico publicado en 2015

Past-in-the-Future. Peak detection improves targeted mass spectrometry imaging

scientific article published on 28 June 2018

Pharmacokinetics and antineoplastic activity of galectin-1-targeting OTX008 in combination with sunitinib.

artículo científico publicado en 2013

Promising in vivo efficacy of the BET bromodomain inhibitor OTX015/MK-8628 in malignant pleural mesothelioma xenografts

artículo científico publicado en 2016

Quality control study of the Italian Group of Cytometry on flow cytometry DNA content measurements: II. Factors affecting inter- and intralaboratory variability

scientific article published on 01 April 1997

Representing cell cycle data.

artículo científico publicado en 1986

Retinoic Acid Sensitivity of Triple-Negative Breast Cancer Cells Characterized by Constitutive Activation of the notch1 Pathway: The Role of Rarβ

artículo científico publicado en 2020

Self-Assembling PCL-Based Nanoparticles as PTX Solubility Enhancer Excipients

artículo científico publicado en 2018

Sensitivity of flow cytometric data to variations in cell cycle parameters.

artículo científico publicado en 1987

Small interfering RNA delivery through positively charged polymer nanoparticles.

artículo científico publicado en 2016

Solar UV radiation: differential effectiveness of UVB subcomponents in causing cell death, micronucleus induction and delayed expression of heritable damage in human hybrid cells.

artículo científico publicado en 2001

Synthesis of surfactant free PCL-PEG brushed nanoparticles with tunable degradation kinetics.

artículo científico publicado en 2013

The antitumor efficacy of cytotoxic drugs is potentiated by treatment with PNU 145156E, a growth-factor-complexing molecule

artículo científico publicado en 1999

The contribution of p53 in the dynamics of cell cycle response to DNA damage interpreted by a mathematical model.

artículo científico publicado en 2007

The vascular targeting property of paclitaxel is enhanced by SU6668, a receptor tyrosine kinase inhibitor, causing apoptosis of endothelial cells and inhibition of angiogenesis

artículo científico publicado en 2006

Time- and dose-dependence of DNA fragmentation induced by anticancer agents: a flow cytometric study

scientific article published on 01 January 1997

Tumor progression and metastatic dissemination in ovarian cancer after dose-dense or conventional paclitaxel and cisplatin plus bevacizumab

artículo científico publicado en 2018

Lista de obras de Paolo Ubezio

A biodistribution study of PEGylated PCL-based nanoparticles in C57BL/6 mice bearing B16/F10 melanoma.

A generalised age- and phase-structured model of human tumour cell populations both unperturbed and exposed to a range of cancer therapies.

A mathematical model of the effect of aging on bone marrow cells colonizing the thymus.

A methyl methacrylate-HEMA-CL(n) copolymerization investigation: from kinetics to bioapplications.

A specific miRNA signature correlates with complete pathological response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer.

ActivinA: a new leukemia-promoting factor conferring migratory advantage to B-cell precursor-acute lymphoblastic leukemic cells

Anthracycline resistance: cytofluorometric study on infantile lymphoblastic leukemia

Application of 3D Mass Spectrometry Imaging to TKIs

Beyond The T/C Ratio: Old And New Anticancer Activity Scores In Vivo

Biochemical, morphological and flow-cytometric evaluation of the effects of hexachlorobenzene on rat liver

Calpain as a multi-site regulator of cell cycle.

Cediranib combined with chemotherapy reduces tumor dissemination and prolongs the survival of mice bearing patient-derived ovarian cancer xenografts with different responsiveness to cisplatin

Cell cycle simulation for flow cytometry.

Cell killing and resistance in pre-operative breast cancer chemotherapy

Cell kinetics of human ovarian cancer with in vivo administration of bromodeoxyuridine

Cell loss and the concept of potential doubling time ⬇️

Cellular and molecular determinants of all-trans retinoic acid sensitivity in breast cancer: Luminal phenotype and RARα expression

Characterization of cyclin B1 expression in human cancer cell lines by a new three-parameter BrdUrd/cyclin B1/DNA analysis

Combination of PPARγ Agonist Pioglitazone and Trabectedin Induce Adipocyte Differentiation to Overcome Trabectedin Resistance in Myxoid Liposarcomas

Combination of the new minor groove alkylator tallimustine and melphalan

Combination of trabectedin and irinotecan is highly effective in a human rhabdomyosarcoma xenograft

Comparison of histone variant synthesis in human lymphocytic leukemia cells and in normal lymphocytes

Cytologic and flow cytometric DNA analysis of multinucleated tumor cells and derived microcells

DNA damage, cytotoxic effect and cell-cycle perturbation of Hoechst 33342 on L1210 cells in vitro ⬇️

Doxorubicin and m-AMSA induced DNA damage in blast cells from AML patients

Dynamic rendering of the heterogeneous cell response to anticancer treatments

Dynamics of cell cycle phase perturbations by trabectedin (ET-743) in nucleotide excision repair (NER)-deficient and NER-proficient cells, unravelled by a novel mathematical simulation approach.

Effective combination of ET-743 and doxorubicin in sarcoma: preclinical studies

Enhanced cell cycle perturbation and apoptosis mediate the synergistic effects of ST1926 and ATRA in neuroblastoma preclinical models

Fate of PLA and PCL-Based Polymeric Nanocarriers in Cellular and Animal Models of Triple-Negative Breast Cancer.

Flow-cytometric analysis of DNA distribution after VP16-213 treatment of Lewis lung carcinoma

From flow cytometric BrdUrd data to cell population growth and doubling time ⬇️

Genotoxic damage induced by doxorubicin in two human melanoma cell lines

HER2-positive breast-cancer cell lines are sensitive to KDM5 inhibition: definition of a gene-expression model for the selection of sensitive cases

Heterogeneous cell response to topotecan in a CFSE-based proliferation test.

Histone H1(0) is synthesized by human lymphocytic leukemia cells but not by normal lymphocytes

In vivo measurement of vascular modulation in experimental tumors using a fluorescent contrast agent

Increasing 1-beta-D-arabinofuranosylcytosine efficacy by scheduled dosing intervals based on direct measurements of bone marrow cell kinetics

Inhibition of SIRT2 potentiates the anti-motility activity of taxanes: implications for antineoplastic combination therapies.

Integrated experimental and simulation study of the response to sequential treatment with erlotinib and gemcitabine in pancreatic cancer.

Integrated multiplatform method for in vitro quantitative assessment of cellular uptake for fluorescent polymer nanoparticles.

Interoperability of time series cytometric data: a cross platform approach for modeling tumor heterogeneity.

Interpreting cell cycle effects of drugs: the case of melphalan.

Intracellular doxorubicin concentrations and drug-induced DNA damage in a human colon adenocarcinoma cell line and in a drug-resistant subline.

Intracellular drug concentration and DNA damage in human childhood leukemic cells exposed to doxorubicin

Intracellular glutathione heterogeneity in L1210 murine leukemia sublines made resistant to DNA-interacting anti-neoplastic agents.

Kinetic heterogeneity of an experimental tumour revealed by BrdUrd incorporation and mathematical modelling.

Measuring the complexity of cell cycle arrest and killing of drugs: kinetics of phase-specific effects induced by taxol

Microcomputer experience in analysis of flow cytometric DNA distributions

Miniaturizing bromodeoxyuridine incorporation enables the usage of flow cytometry for cell cycle analysis of adherent tissue culture cells for high throughput screening.

Modeling Cytostatic and Cytotoxic Responses to New Treatment Regimens for Ovarian Cancer

Modeling of non-small cell lung cancer volume changes during CT-based image guided radiotherapy: patterns observed and clinical implications

Modelling the balance between quiescence and cell death in normal and tumour cell populations.

PEGylated Nanoparticles Obtained through Emulsion Polymerization as Paclitaxel Carriers

Past-in-the-Future. Peak detection improves targeted mass spectrometry imaging

Pharmacokinetics and antineoplastic activity of galectin-1-targeting OTX008 in combination with sunitinib.

Promising in vivo efficacy of the BET bromodomain inhibitor OTX015/MK-8628 in malignant pleural mesothelioma xenografts

Quality control study of the Italian Group of Cytometry on flow cytometry DNA content measurements: II. Factors affecting inter- and intralaboratory variability

Representing cell cycle data.

Retinoic Acid Sensitivity of Triple-Negative Breast Cancer Cells Characterized by Constitutive Activation of the notch1 Pathway: The Role of Rarβ

Self-Assembling PCL-Based Nanoparticles as PTX Solubility Enhancer Excipients

Sensitivity of flow cytometric data to variations in cell cycle parameters.

Small interfering RNA delivery through positively charged polymer nanoparticles.

Solar UV radiation: differential effectiveness of UVB subcomponents in causing cell death, micronucleus induction and delayed expression of heritable damage in human hybrid cells.

Synthesis of surfactant free PCL-PEG brushed nanoparticles with tunable degradation kinetics.

The antitumor efficacy of cytotoxic drugs is potentiated by treatment with PNU 145156E, a growth-factor-complexing molecule

The contribution of p53 in the dynamics of cell cycle response to DNA damage interpreted by a mathematical model.

The vascular targeting property of paclitaxel is enhanced by SU6668, a receptor tyrosine kinase inhibitor, causing apoptosis of endothelial cells and inhibition of angiogenesis

Time- and dose-dependence of DNA fragmentation induced by anticancer agents: a flow cytometric study

Tumor progression and metastatic dissemination in ovarian cancer after dose-dense or conventional paclitaxel and cisplatin plus bevacizumab