Lista de obras - Mar Orzaez - Dominio Público Uruguay

A NIR light-triggered drug delivery system using core-shell gold nanostars-mesoporous silica nanoparticles based on multiphoton absorption photo-dissociation of 2-nitrobenzyl PEG

scientific article published on 11 July 2019

A polymeric nanomedicine diminishes inflammatory events in renal tubular cells

artículo científico publicado en 2013

ATP-noncompetitive inhibitors of CDK-cyclin complexes.

artículo científico publicado en 2009

Altered mitochondria morphology and cell metabolism in Apaf1-deficient cells.

artículo científico publicado en 2014

Apaf-1 inhibitors protect from unwanted cell death in in vivo models of kidney ischemia and chemotherapy induced ototoxicity

artículo científico publicado en 2014

Apaf1 inhibition promotes cell recovery from apoptosis.

artículo científico publicado en 2015

Azobenzene Polyesters Used as Gate-Like Scaffolds in Nanoscopic Hybrid Systems

artículo científico publicado en 2012

Biocompatibility Reduces Inflammation-Induced Apoptosis in Mesothelial Cells Exposed to Peritoneal Dialysis Fluid

artículo científico publicado en 2015

Caspase 3 Targeted Cargo Delivery in Apoptotic Cells Using Capped Mesoporous Silica Nanoparticles

scientific article published on 10 September 2015

Cathepsin-B induced controlled release from peptide-capped mesoporous silica nanoparticles.

artículo científico publicado en 2014

Characterization of dequalinium as a XIAP antagonist that targets the BIR2 domain

scientific article published on 01 May 2011

Cytochrome c speeds up caspase cascade activation by blocking 14-3-3ε-dependent Apaf-1 inhibition

artículo científico publicado en 2018

EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology

artículo científico publicado en 2019

Efficient Synthesis of Conformationally Restricted Apoptosis Inhibitors Bearing a Triazole Moiety

artículo científico publicado en 2015

Enzyme-responsive intracellular-controlled release using silica mesoporous nanoparticles capped with ε-poly-L-lysine.

artículo científico publicado en 2014

Gold Nanostars Coated with Mesoporous Silica Are Effective and Nontoxic Photothermal Agents Capable of Gate Keeping and Laser-Induced Drug Release

scientific article published on 08 August 2018

Hybrid Mesoporous Nanocarriers Act by Processing Logic Tasks: Toward the Design of Nanobots Capable of Reading Information from the Environment

artículo científico publicado en 2018

Identification and validation of uterine stimulant methylergometrine as a potential inhibitor of caspase-1 activation

artículo científico publicado en 2017

Identification of an hexapeptide that binds to a surface pocket in cyclin A and inhibits the catalytic activity of the complex cyclin-dependent kinase 2-cyclin A.

artículo científico publicado en 2006

In vivo discovery of a peptide that prevents CUG–RNA hairpin formation and reverses RNA toxicity in myotonic dystrophy models ⬇️

artículo científico publicado el 5 de julio de 2011

Inactivation of Apaf1 reduces the formation of mutant huntingtin-dependent aggregates and cell death.

artículo científico publicado en 2014

Influence of proline residues in transmembrane helix packing.

artículo científico publicado en 2004

Intrinsic caspase-8 activation mediates sensitization of erlotinib-resistant tumor cells to erlotinib/cell-cycle inhibitors combination treatment.

artículo científico publicado en 2012

Janus Gold Nanostars-Mesoporous Silica Nanoparticles for NIR-Light-Triggered Drug Delivery

artículo científico publicado en 2019

L-Aminoacid Oxidase from Bothrops leucurus Venom Induces Nephrotoxicity via Apoptosis and Necrosis

artículo científico publicado en 2015

Membrane promotes tBID interaction with BCL(XL).

artículo científico publicado en 2009

Minocycline inhibits cell death and decreases mutant Huntingtin aggregation by targeting Apaf-1.

artículo científico publicado en 2011

Modulation of cellular apoptosis with apoptotic protease-activating factor 1 (Apaf-1) inhibitors

scientific journal article

Nitration of tyrosine 74 prevents human cytochrome c to play a key role in apoptosis signaling by blocking caspase-9 activation.

artículo científico publicado en 2010

Optimizing the control of apoptosis by amide/triazole isosteric substitution in a constrained peptoid.

artículo científico publicado en 2013

Peptides and peptide mimics as modulators of apoptotic pathways.

artículo científico publicado en 2009

Peptides derived from the transmembrane domain of Bcl-2 proteins as potential mitochondrial priming tools

artículo científico publicado en 2014

Polar/Ionizable residues in transmembrane segments: effects on helix-helix packing.

artículo científico publicado en 2012

Polypeptide modulators of caspase recruitment domain (CARD)-CARD-mediated protein-protein interactions.

artículo científico publicado en 2011

Rational design of a cyclin A fluorescent peptide sensor.

artículo científico publicado en 2011

Rational design of new class of BH3-mimetics as inhibitors of the Bcl-xL protein.

artículo científico publicado en 2011

Role of CDK5/cyclin complexes in ischemia-induced death and survival of renal tubular cells.

artículo científico publicado en 2014

Specific nitration of tyrosines 46 and 48 makes cytochromecassemble a non-functional apoptosome

artículo científico publicado en 2011

Synthesis of enantiomerically pure perhydro-1,4-diazepine-2,5-dione and 1,4-piperazine-2,5-dione derivatives exhibiting potent activity as apoptosis inhibitors

scientific article published on 29 September 2012

Temperature-controlled release by changes in the secondary structure of peptides anchored onto mesoporous silica supports

scientific article published on 12 February 2014

The C-terminal Domains of Apoptotic BH3-only Proteins Mediate Their Insertion into Distinct Biological Membranes.

artículo científico publicado en 2016

Tyrosine phosphorylation turns alkaline transition into a biologically relevant process and makes human cytochrome c behave as an anti-apoptotic switch.

artículo científico publicado en 2011

Lista de obras de Mar Orzaez

A NIR light-triggered drug delivery system using core-shell gold nanostars-mesoporous silica nanoparticles based on multiphoton absorption photo-dissociation of 2-nitrobenzyl PEG

A polymeric nanomedicine diminishes inflammatory events in renal tubular cells

ATP-noncompetitive inhibitors of CDK-cyclin complexes.

Altered mitochondria morphology and cell metabolism in Apaf1-deficient cells.

Apaf-1 inhibitors protect from unwanted cell death in in vivo models of kidney ischemia and chemotherapy induced ototoxicity

Apaf1 inhibition promotes cell recovery from apoptosis.

Azobenzene Polyesters Used as Gate-Like Scaffolds in Nanoscopic Hybrid Systems

Biocompatibility Reduces Inflammation-Induced Apoptosis in Mesothelial Cells Exposed to Peritoneal Dialysis Fluid

Caspase 3 Targeted Cargo Delivery in Apoptotic Cells Using Capped Mesoporous Silica Nanoparticles

Cathepsin-B induced controlled release from peptide-capped mesoporous silica nanoparticles.

Characterization of dequalinium as a XIAP antagonist that targets the BIR2 domain

Cytochrome c speeds up caspase cascade activation by blocking 14-3-3ε-dependent Apaf-1 inhibition

EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology

Efficient Synthesis of Conformationally Restricted Apoptosis Inhibitors Bearing a Triazole Moiety

Enzyme-responsive intracellular-controlled release using silica mesoporous nanoparticles capped with ε-poly-L-lysine.

Gold Nanostars Coated with Mesoporous Silica Are Effective and Nontoxic Photothermal Agents Capable of Gate Keeping and Laser-Induced Drug Release

Hybrid Mesoporous Nanocarriers Act by Processing Logic Tasks: Toward the Design of Nanobots Capable of Reading Information from the Environment

Identification and validation of uterine stimulant methylergometrine as a potential inhibitor of caspase-1 activation

Identification of an hexapeptide that binds to a surface pocket in cyclin A and inhibits the catalytic activity of the complex cyclin-dependent kinase 2-cyclin A.

In vivo discovery of a peptide that prevents CUG–RNA hairpin formation and reverses RNA toxicity in myotonic dystrophy models ⬇️

Inactivation of Apaf1 reduces the formation of mutant huntingtin-dependent aggregates and cell death.

Influence of proline residues in transmembrane helix packing.

Intrinsic caspase-8 activation mediates sensitization of erlotinib-resistant tumor cells to erlotinib/cell-cycle inhibitors combination treatment.

Janus Gold Nanostars-Mesoporous Silica Nanoparticles for NIR-Light-Triggered Drug Delivery

L-Aminoacid Oxidase from Bothrops leucurus Venom Induces Nephrotoxicity via Apoptosis and Necrosis

Membrane promotes tBID interaction with BCL(XL).

Minocycline inhibits cell death and decreases mutant Huntingtin aggregation by targeting Apaf-1.

Modulation of cellular apoptosis with apoptotic protease-activating factor 1 (Apaf-1) inhibitors

Nitration of tyrosine 74 prevents human cytochrome c to play a key role in apoptosis signaling by blocking caspase-9 activation.

Optimizing the control of apoptosis by amide/triazole isosteric substitution in a constrained peptoid.

Peptides and peptide mimics as modulators of apoptotic pathways.

Peptides derived from the transmembrane domain of Bcl-2 proteins as potential mitochondrial priming tools

Polar/Ionizable residues in transmembrane segments: effects on helix-helix packing.

Polypeptide modulators of caspase recruitment domain (CARD)-CARD-mediated protein-protein interactions.

Rational design of a cyclin A fluorescent peptide sensor.

Rational design of new class of BH3-mimetics as inhibitors of the Bcl-xL protein.

Role of CDK5/cyclin complexes in ischemia-induced death and survival of renal tubular cells.

Specific nitration of tyrosines 46 and 48 makes cytochromecassemble a non-functional apoptosome

Synthesis of enantiomerically pure perhydro-1,4-diazepine-2,5-dione and 1,4-piperazine-2,5-dione derivatives exhibiting potent activity as apoptosis inhibitors

Temperature-controlled release by changes in the secondary structure of peptides anchored onto mesoporous silica supports

The C-terminal Domains of Apoptotic BH3-only Proteins Mediate Their Insertion into Distinct Biological Membranes.

Tyrosine phosphorylation turns alkaline transition into a biologically relevant process and makes human cytochrome c behave as an anti-apoptotic switch.