Lista de obras - Christoph Rader - Dominio Público Uruguay

"One, if by land, and two, if by sea": bispecific antibodies join the revolution

scientific article published on 01 February 2019

A CD19/CD3 bispecific antibody for effective immunotherapy of chronic lymphocytic leukemia in the ibrutinib era.

artículo científico publicado en 2018

A Sortase A Programmable Phage Display Format for Improved Panning of Fab Antibody Libraries

article

A chemical adaptor system designed to link a tumor-targeting device with a prodrug and an enzymatic trigger

artículo científico publicado en 2003

A direct interaction of axonin-1 with NgCAM-related cell adhesion molecule (NrCAM) results in guidance, but not growth of commissural axons.

artículo científico publicado en 2000

A human monoclonal antibody drug and target discovery platform for B-cell chronic lymphocytic leukemia based on allogeneic hematopoietic stem cell transplantation and phage display.

artículo científico publicado en 2009

A humanized aldolase antibody for selective chemotherapy and adaptor immunotherapy

artículo científico publicado en 2003

A new immunochemical strategy for triple-negative breast cancer therapy

artículo científico publicado en 2021

A novel adoptive transfer model of chronic lymphocytic leukemia suggests a key role for T lymphocytes in the disease

artículo científico publicado en 2011

A novel high-affinity human monoclonal antibody to mesothelin.

artículo científico publicado en 2011

A phage display approach for rapid antibody humanization: designed combinatorial V gene libraries.

artículo científico publicado en 1998

Affinity maturation, humanization, and co-crystallization of a rabbit anti-human ROR2 monoclonal antibody for therapeutic applications

scientific article published on 19 March 2020

Aldolase antibody activation of prodrugs of potent aldehyde-containing cytotoxics for selective chemotherapy

artículo científico publicado en 2004

An Engineered Arginine Residue of Unusual pH-Sensitive Reactivity Facilitates Site-Selective Antibody Conjugation

artículo científico publicado en 2021

An IgG1-like bispecific antibody targeting CD52 and CD20 for the treatment of B-cell malignancies

scientific article published on 24 August 2018

An engineered selenocysteine defines a unique class of antibody derivatives

artículo científico publicado en 2008

Analysis of cell-cell contact mediated by Ig superfamily cell adhesion molecules.

artículo científico publicado en 2013

Analysis of cell-cell contact mediated by Ig superfamily cell adhesion molecules.

artículo científico publicado en 2001

Angucyclines and Angucyclinones from Streptomyces sp. CB01913 Featuring C-Ring Cleavage and Expansion ⬇️

artículo científico publicado en 2015

Antibody conjugation via one and two C-terminal selenocysteines.

artículo científico publicado en 2013

Antibody libraries in drug and target discovery.

artículo científico publicado en 2001

Application of a trifunctional reactive linker for the construction of antibody-drug hybrid conjugates

artículo científico publicado en 2008

Application of strain-promoted azide-alkyne cycloaddition and tetrazine ligation to targeted Fc-drug conjugates.

artículo científico publicado en 2012

Assessment of reagents for selenocysteine conjugation and the stability of selenocysteine adducts

artículo científico publicado en 2016

Axonin-1/TAG-1 mediates cell-cell adhesion by a cis-assisted trans-interaction.

artículo científico publicado en 2001

Bispecific antibodies in cancer immunotherapy

scientific article published on 13 December 2019

Bortezomib resistance in mantle cell lymphoma is associated with plasmacytic differentiation

artículo científico publicado en 2010

CAR T cells targeting αvβ3 integrin are effective against advanced cancer in preclinical models

scientific article published on 10 July 2018

Carlos F. Barbas III (1964-2014): Visionary at the interface of chemistry and biology

artículo científico

Characterization of TnmH as an O-Methyltransferase Revealing In-sights into Tiancimycin Biosynthesis and Enabling a Biocatalytic Strategy to Prepare Antibody-Tiancimycin Conjugates

artículo científico publicado en 2020

Chemical adaptor immunotherapy: design, synthesis, and evaluation of novel integrin-targeting devices.

artículo científico publicado en 2004

Chemical biology: How to minimalize antibodies

artículo científico

Chemically Programmed Bispecific Antibodies in Diabody Format

artículo científico

Chemically programmable and switchable CAR-T therapy

artículo científico publicado en 2020

Chemically programmed antibodies.

artículo científico

Chemically programmed bispecific antibodies that recruit and activate T cells

artículo científico publicado en 2012

Chemically programmed monoclonal antibodies for cancer therapy: adaptor immunotherapy based on a covalent antibody catalyst.

artículo científico publicado en 2003

Chimeric Antigen Receptor Library Screening Using a Novel NF-κB/NFAT Reporter Cell Platform

artículo científico publicado en 2018

Chimeric Rabbit/Human Fab Antibodies Against the Hepatitis B e-antigen and Their Potential Applications in Assay, Characterization and Therapy.

artículo científico publicado en 2017

Chimeric rabbit/human Fab and IgG specific for members of the Nogo-66 receptor family selected for species cross-reactivity with an improved phage display vector

artículo científico publicado en 2006

Cloning, expression, and purification of monoclonal antibodies in scFv-Fc format

artículo científico publicado en 2012

Comparative Studies of the Biosynthetic Gene Clusters for Anthraquinone-Fused Enediynes Shedding Light into the Tailoring Steps of Tiancimycin Biosynthesis

artículo científico publicado en 2018

Contactin-2/TAG-1-directed autoimmunity is identified in multiple sclerosis patients and mediates gray matter pathology in animals

scholarly article

Conventional and Chemically Programmed Asymmetric Bispecific Antibodies Targeting Folate Receptor 1

scientific article published on 21 August 2019

DARTs take aim at BiTEs

artículo científico publicado en 2011

Discovery of ammosesters by mining the Streptomyces uncialis DCA2648 genome revealing new insight into ammosamide biosynthesis ⬇️

artículo científico publicado en 2021

Discrete clusters of axonin-1 and NgCAM at neuronal contact sites: facts and speculations on the regulation of axonal fasciculation.

artículo científico publicado en 1998

Dual-mechanistic antibody-drug conjugate via site-specific selenocysteine/cysteine conjugation

artículo científico publicado en 2019

E. coli expression and purification of Fab antibody fragments

artículo científico publicado en 2009

Engineered production of cancer targeting peptide (CTP)-containing C-1027 in Streptomyces globisporus and biological evaluation

artículo científico publicado en 2016

Engineering Dual Variable Domains for the Generation of Site-Specific Antibody-Drug Conjugates

scientific article published on 01 January 2019

From catalytic asymmetric synthesis to the transcriptional regulation of genes: in vivo and in vitro evolution of proteins.

artículo científico publicado en 2000

From rabbit antibody repertoires to rabbit monoclonal antibodies

artículo científico publicado en 2017

Generation and characterization of a chimeric rabbit/human Fab for co-crystallization of HIV-1 Rev.

artículo científico publicado en 2010

Generation and characterization of a recombinant human CCR5-specific antibody. A phage display approach for rabbit antibody humanization.

artículo científico publicado en 2000

Generation and selection of rabbit antibody libraries by phage display

artículo científico publicado en 2009

Generation and validation of structurally defined antibody-siRNA conjugates

scientific article published on 29 April 2020

Generation of Human Fab Libraries for Phage Display ⬇️

artículo científico publicado el 1 de enero de 2012

Generation of human Fab antibody libraries: PCR amplification and assembly of light- and heavy-chain coding sequences.

artículo científico publicado en 2011

Generation of human scFv antibody libraries: PCR amplification and assembly of light- and heavy-chain coding sequences.

artículo científico publicado en 2011

Generation, affinity maturation, and characterization of a human anti-human NKG2D monoclonal antibody with dual antagonistic and agonistic activity

artículo científico publicado en 2008

Genome Mining of Micromonospora yangpuensis DSM 45577 as a Producer of an Anthraquinone-Fused Enediyne. ⬇️

artículo científico publicado en 2017

Harnessing a catalytic lysine residue for the one-step preparation of homogeneous antibody-drug conjugates

artículo científico publicado en 2017

Harnessing the fcμ receptor for potent and selective cytotoxic therapy of chronic lymphocytic leukemia.

artículo científico publicado en 2014

Human Serum Albumin Domain I Fusion Protein for Antibody Conjugation.

artículo científico

Human/mouse cross-reactive anti-VEGF receptor 2 recombinant antibodies selected from an immune b9 allotype rabbit antibody library.

artículo científico publicado en 2004

IGF1R- and ROR1-Specific CAR T Cells as a Potential Therapy for High Risk Sarcomas.

artículo científico publicado en 2015

Immunogenic Chemotherapy Enhances Recruitment of CAR-T Cells to Lung Tumors and Improves Antitumor Efficacy when Combined with Checkpoint Blockade

artículo científico publicado en 2020

Implications of the HIV-1 Rev dimer structure at 3.2 A resolution for multimeric binding to the Rev response element

artículo científico publicado en 2010

Improving the serum stability of site-specific antibody conjugates with sulfone linkers

artículo científico publicado en 2014

In vivo activity in a catalytic antibody-prodrug system: Antibody catalyzed etoposide prodrug activation for selective chemotherapy

artículo científico publicado en 2001

Integrin alpha(v)beta3 targeted therapy for Kaposi's sarcoma with an in vitro evolved antibody

artículo científico publicado en 2002

Integrin alphaIIbbeta3-specific synthetic human monoclonal antibodies and HCDR3 peptides that potently inhibit platelet aggregation

artículo científico publicado en 2003

Intradiabodies, bispecific, tetravalent antibodies for the simultaneous functional knockout of two cell surface receptors.

artículo científico publicado en 2003

Isolation of human prostate cancer cell reactive antibodies using phage display technology.

artículo científico publicado en 2004

Lenalidomide treatment promotes CD154 expression on CLL cells and enhances production of antibodies by normal B cells through a PI3-kinase-dependent pathway

artículo científico publicado en 2009

Lipid-directed vinculin dimerization

artículo científico

Logic-Gated ROR1 Chimeric Antigen Receptor Expression Rescues T Cell-Mediated Toxicity to Normal Tissues and Enables Selective Tumor Targeting

scientific article published on 01 March 2019

Mechanisms of CNS myelin inhibition: evidence for distinct and neuronal cell type specific receptor systems.

artículo científico publicado en 2008

Mining Naïve Rabbit Antibody Repertoires by Phage Display for Monoclonal Antibodies of Therapeutic Utility

artículo científico

Mining human antibody repertoires

artículo científico publicado en 2010

Molecular basis of the interactions of the Nogo-66 receptor and its homolog NgR2 with myelin-associated glycoprotein: development of NgROMNI-Fc, a novel antagonist of CNS myelin inhibition

scientific journal article

Molecularly defined antibody conjugation through a selenocysteine interface

artículo científico publicado en 2009

Monoclonal antibodies targeting cell surface deposited complement fragment C3d potentiate cancer immunotherapy and eliminate antigen loss variants.

artículo científico publicado en 2015

Mutations derived from horseshoe bat ACE2 orthologs enhance ACE2-Fc neutralization of SARS-CoV-2

artículo científico publicado en 2021

Mutations from bat ACE2 orthologs markedly enhance ACE2-Fc neutralization of SARS-CoV-2

artículo científico publicado en 2020

Neurite fasciculation mediated by complexes of axonin-1 and Ng cell adhesion molecule

artículo científico publicado en 1998

Neutralization of Burkholderia pseudomallei protease by Fabs generated through phage display

artículo científico publicado en 2005

New chemical adaptor unit designed to release a drug from a tumor targeting device by enzymatic triggering

artículo científico publicado en 2004

Overview on concepts and applications of Fab antibody fragments

artículo científico publicado en 2009

Phage display of combinatorial antibody libraries.

artículo científico publicado en 1997

Phenotypic knockout of VEGF-R2 and Tie-2 with an intradiabody reduces tumor growth and angiogenesis in vivo

artículo científico publicado en 2005

Potent and selective antitumor activity of a T cell-engaging bispecific antibody targeting a membrane-proximal epitope of ROR1

artículo científico publicado en 2018

Prodrugs of dynemicin analogs for selective chemotherapy mediated by an aldolase catalytic Ab.

artículo científico publicado en 2004

ROR1-targeted delivery of OSU-2S, a nonimmunosuppressive FTY720 derivative, exerts potent cytotoxicity in mantle-cell lymphoma in vitro and in vivo

artículo científico

ROR1-targeted delivery of miR-29b induces cell cycle arrest and therapeutic benefit in vivo in a CLL mouse model

artículo científico publicado en 2019

Rabbit immune repertoires as sources for therapeutic monoclonal antibodies: the impact of kappa allotype-correlated variation in cysteine content on antibody libraries selected by phage display

artículo científico publicado en 2003

Rabbit models of human diseases for diagnostics and therapeutics development

article

Receptor affinity and extracellular domain modifications affect tumor recognition by ROR1-specific chimeric antigen receptor T cells

scientific article published on 25 April 2013

Recognition of antigen-specific B-cell receptors from chronic lymphocytic leukemia patients by synthetic antigen surrogates

artículo científico publicado en 2014

Redirecting cytotoxic T cells with chemically programmed antibodies

artículo científico publicado en 2020

Restricted cell surface expression of receptor tyrosine kinase ROR1 in pediatric B-lineage acute lymphoblastic leukemia suggests targetability with therapeutic monoclonal antibodies

artículo científico publicado en 2012

SARS-CoV-2 spike-protein D614G mutation increases virion spike density and infectivity

artículo científico publicado en 2020

Safety of targeting ROR1 for cancer immunotherapy with chimeric antigen receptor-modified T cells in a primate model

artículo científico publicado en 2014

Safety of targeting ROR1 in primates with chimeric antigen receptor-modified T cells

artículo científico publicado en 2014

Selection of Human Fab Libraries by Phage Display ⬇️

artículo científico publicado el 1 de enero de 2012

Selection of apoptotic cell specific human antibodies from adult bone marrow

artículo científico publicado en 2014

Siglec-6 on Chronic Lymphocytic Leukemia Cells Is a Target for Post-Allogeneic Hematopoietic Stem Cell Transplantation Antibodies

scholarly article by Jing Chang et al published September 2018 in Cancer immunology research

Site-Selective Antibody Functionalization via Orthogonally Reactive Arginine and Lysine Residues

scientific article published on 20 June 2019

Site-Specific Antibody-Drug Conjugates in Triple Variable Domain Fab Format

scientific article published on 14 May 2020

Site-Specific Dual Antibody Conjugation via Engineered Cysteine and Selenocysteine Residues.

artículo científico publicado en 2015

Site-Specific Lysine Arylation as an Alternative Bioconjugation Strategy for Chemically Programmed Antibodies and Antibody-Drug Conjugates

scientific article published on 01 November 2019

Six-packed antibodies punch better

scientific article published on 01 September 2019

Small molecule drug activity in melanoma models may be dramatically enhanced with an antibody effector

scientific article published on 01 September 2006

Stable and Potent Selenomab-Drug Conjugates.

artículo científico

Strain Prioritization and Genome Mining for Enediyne Natural Products

artículo científico publicado en 2016

Synthesis of the next-generation therapeutic antibodies that combine cell targeting and antibody-catalyzed prodrug activation.

artículo científico publicado en 2007

Tagging the Untaggable: A Difluoroalkyl-Sulfinate Ketone-Based Reagent for Direct C-H Functionalization of Bioactive Heteroarenes

artículo científico publicado en 2016

Targeting Stereotyped B Cell Receptors from Chronic Lymphocytic Leukemia Patients with Synthetic Antigen Surrogates

artículo científico publicado en 2016

Targeting malignant B cells with an immunotoxin against ROR1

artículo científico publicado en 2012

Targeting the Fcμ-receptor in chronic lymphocytic leukemia with a novel IgM-derived antibody-drug conjugate

artículo científico publicado en 2013

Targeting tumor angiogenesis with adenovirus-delivered anti-Tie-2 intrabody

scientific article published on 01 February 2005

The B-cell tumor-associated antigen ROR1 can be targeted with T cells modified to express a ROR1-specific chimeric antigen receptor.

artículo científico publicado en 2010

The New Zealand black mouse as a model for the development and progression of chronic lymphocytic leukemia

artículo científico publicado en 2010

The Nogo-66 receptor homolog NgR2 is a sialic acid-dependent receptor selective for myelin-associated glycoprotein

scientific journal article

The axonally secreted cell adhesion molecule, axonin-1. Primary structure, immunoglobulin-like and fibronectin-type-III-like domains and glycosyl-phosphatidylinositol anchorage

artículo científico publicado el 1 de marzo de 1992

The contactin-related protein FAR-2 defines purkinje cell clusters and labels subpopulations of climbing fibers in the developing cerebellum.

artículo científico publicado en 2001

The gene of chicken axonin-1. Complete structure and analysis of the promoter.

artículo científico publicado en 1995

The nonsignaling extracellular spacer domain of chimeric antigen receptors is decisive for in vivo antitumor activity.

artículo científico publicado en 2014

The rabbit antibody repertoire as a novel source for the generation of therapeutic human antibodies.

artículo científico publicado en 2000

Therapeutic potential and challenges of targeting receptor tyrosine kinase ROR1 with monoclonal antibodies in B-cell malignancies

artículo científico publicado en 2011

Tumor antigen ROR1 targeted drug delivery mediated selective leukemic but not normal B-cell cytotoxicity in chronic lymphocytic leukemia

artículo científico publicado en 2014

Unique cell surface expression of receptor tyrosine kinase ROR1 in human B-cell chronic lymphocytic leukemia.

artículo científico publicado en 2008

Using antibody catalysis to study the outcome of multiple evolutionary trials of a chemical task

artículo científico publicado en 2000

Utilization of Selenocysteine for Site-Specific Antibody Conjugation.

artículo científico

cDNA cloning, structural features, and eucaryotic expression of human TAG-1/axonin-1

artículo científico publicado en 1993

Lista de obras de Christoph Rader

"One, if by land, and two, if by sea": bispecific antibodies join the revolution

A CD19/CD3 bispecific antibody for effective immunotherapy of chronic lymphocytic leukemia in the ibrutinib era.

A Sortase A Programmable Phage Display Format for Improved Panning of Fab Antibody Libraries

A chemical adaptor system designed to link a tumor-targeting device with a prodrug and an enzymatic trigger

A direct interaction of axonin-1 with NgCAM-related cell adhesion molecule (NrCAM) results in guidance, but not growth of commissural axons.

A human monoclonal antibody drug and target discovery platform for B-cell chronic lymphocytic leukemia based on allogeneic hematopoietic stem cell transplantation and phage display.

A humanized aldolase antibody for selective chemotherapy and adaptor immunotherapy

A new immunochemical strategy for triple-negative breast cancer therapy

A novel adoptive transfer model of chronic lymphocytic leukemia suggests a key role for T lymphocytes in the disease

A novel high-affinity human monoclonal antibody to mesothelin.

A phage display approach for rapid antibody humanization: designed combinatorial V gene libraries.

Affinity maturation, humanization, and co-crystallization of a rabbit anti-human ROR2 monoclonal antibody for therapeutic applications

Aldolase antibody activation of prodrugs of potent aldehyde-containing cytotoxics for selective chemotherapy

An Engineered Arginine Residue of Unusual pH-Sensitive Reactivity Facilitates Site-Selective Antibody Conjugation

An IgG1-like bispecific antibody targeting CD52 and CD20 for the treatment of B-cell malignancies

An engineered selenocysteine defines a unique class of antibody derivatives

Analysis of cell-cell contact mediated by Ig superfamily cell adhesion molecules.

Analysis of cell-cell contact mediated by Ig superfamily cell adhesion molecules.

Angucyclines and Angucyclinones from Streptomyces sp. CB01913 Featuring C-Ring Cleavage and Expansion ⬇️

Antibody conjugation via one and two C-terminal selenocysteines.

Antibody libraries in drug and target discovery.

Application of a trifunctional reactive linker for the construction of antibody-drug hybrid conjugates

Application of strain-promoted azide-alkyne cycloaddition and tetrazine ligation to targeted Fc-drug conjugates.

Assessment of reagents for selenocysteine conjugation and the stability of selenocysteine adducts

Axonin-1/TAG-1 mediates cell-cell adhesion by a cis-assisted trans-interaction.

Bispecific antibodies in cancer immunotherapy

Bortezomib resistance in mantle cell lymphoma is associated with plasmacytic differentiation

CAR T cells targeting αvβ3 integrin are effective against advanced cancer in preclinical models

Carlos F. Barbas III (1964-2014): Visionary at the interface of chemistry and biology

Characterization of TnmH as an O-Methyltransferase Revealing In-sights into Tiancimycin Biosynthesis and Enabling a Biocatalytic Strategy to Prepare Antibody-Tiancimycin Conjugates

Chemical adaptor immunotherapy: design, synthesis, and evaluation of novel integrin-targeting devices.

Chemical biology: How to minimalize antibodies

Chemically Programmed Bispecific Antibodies in Diabody Format

Chemically programmable and switchable CAR-T therapy

Chemically programmed antibodies.

Chemically programmed bispecific antibodies that recruit and activate T cells

Chemically programmed monoclonal antibodies for cancer therapy: adaptor immunotherapy based on a covalent antibody catalyst.

Chimeric Antigen Receptor Library Screening Using a Novel NF-κB/NFAT Reporter Cell Platform

Chimeric Rabbit/Human Fab Antibodies Against the Hepatitis B e-antigen and Their Potential Applications in Assay, Characterization and Therapy.

Chimeric rabbit/human Fab and IgG specific for members of the Nogo-66 receptor family selected for species cross-reactivity with an improved phage display vector

Cloning, expression, and purification of monoclonal antibodies in scFv-Fc format

Comparative Studies of the Biosynthetic Gene Clusters for Anthraquinone-Fused Enediynes Shedding Light into the Tailoring Steps of Tiancimycin Biosynthesis

Contactin-2/TAG-1-directed autoimmunity is identified in multiple sclerosis patients and mediates gray matter pathology in animals

Conventional and Chemically Programmed Asymmetric Bispecific Antibodies Targeting Folate Receptor 1

DARTs take aim at BiTEs

Discovery of ammosesters by mining the Streptomyces uncialis DCA2648 genome revealing new insight into ammosamide biosynthesis ⬇️

Discrete clusters of axonin-1 and NgCAM at neuronal contact sites: facts and speculations on the regulation of axonal fasciculation.

Dual-mechanistic antibody-drug conjugate via site-specific selenocysteine/cysteine conjugation

E. coli expression and purification of Fab antibody fragments

Engineered production of cancer targeting peptide (CTP)-containing C-1027 in Streptomyces globisporus and biological evaluation

Engineering Dual Variable Domains for the Generation of Site-Specific Antibody-Drug Conjugates

From catalytic asymmetric synthesis to the transcriptional regulation of genes: in vivo and in vitro evolution of proteins.

From rabbit antibody repertoires to rabbit monoclonal antibodies

Generation and characterization of a chimeric rabbit/human Fab for co-crystallization of HIV-1 Rev.

Generation and characterization of a recombinant human CCR5-specific antibody. A phage display approach for rabbit antibody humanization.

Generation and selection of rabbit antibody libraries by phage display

Generation and validation of structurally defined antibody-siRNA conjugates

Generation of Human Fab Libraries for Phage Display ⬇️

Generation of human Fab antibody libraries: PCR amplification and assembly of light- and heavy-chain coding sequences.

Generation of human scFv antibody libraries: PCR amplification and assembly of light- and heavy-chain coding sequences.

Generation, affinity maturation, and characterization of a human anti-human NKG2D monoclonal antibody with dual antagonistic and agonistic activity

Genome Mining of Micromonospora yangpuensis DSM 45577 as a Producer of an Anthraquinone-Fused Enediyne. ⬇️

Harnessing a catalytic lysine residue for the one-step preparation of homogeneous antibody-drug conjugates

Harnessing the fcμ receptor for potent and selective cytotoxic therapy of chronic lymphocytic leukemia.

Human Serum Albumin Domain I Fusion Protein for Antibody Conjugation.

Human/mouse cross-reactive anti-VEGF receptor 2 recombinant antibodies selected from an immune b9 allotype rabbit antibody library.

IGF1R- and ROR1-Specific CAR T Cells as a Potential Therapy for High Risk Sarcomas.

Immunogenic Chemotherapy Enhances Recruitment of CAR-T Cells to Lung Tumors and Improves Antitumor Efficacy when Combined with Checkpoint Blockade

Implications of the HIV-1 Rev dimer structure at 3.2 A resolution for multimeric binding to the Rev response element

Improving the serum stability of site-specific antibody conjugates with sulfone linkers

In vivo activity in a catalytic antibody-prodrug system: Antibody catalyzed etoposide prodrug activation for selective chemotherapy

Integrin alpha(v)beta3 targeted therapy for Kaposi's sarcoma with an in vitro evolved antibody

Integrin alphaIIbbeta3-specific synthetic human monoclonal antibodies and HCDR3 peptides that potently inhibit platelet aggregation

Intradiabodies, bispecific, tetravalent antibodies for the simultaneous functional knockout of two cell surface receptors.

Isolation of human prostate cancer cell reactive antibodies using phage display technology.

Lenalidomide treatment promotes CD154 expression on CLL cells and enhances production of antibodies by normal B cells through a PI3-kinase-dependent pathway

Lipid-directed vinculin dimerization

Logic-Gated ROR1 Chimeric Antigen Receptor Expression Rescues T Cell-Mediated Toxicity to Normal Tissues and Enables Selective Tumor Targeting

Mechanisms of CNS myelin inhibition: evidence for distinct and neuronal cell type specific receptor systems.