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Lista de obras de Valerie L Sim

14-3-3 and enolase abundances in the CSF of Prion diseased rats

scientific article published on 12 September 2018

A novel mechanism of phenotypic heterogeneity in Creutzfeldt-Jakob disease

scientific article published on 19 June 2020

Acute bilateral opercular strokes causing loss of emotional facial movements.

artículo científico publicado en 2005

Asymmetric-flow field-flow fractionation of prions reveals a strain-specific continuum of quaternary structures with protease resistance developing at a hydrodynamic radius of 15 nm

artículo científico publicado en 2021

Bile Acids Reduce Prion Conversion, Reduce Neuronal Loss, and Prolong Male Survival in Models of Prion Disease.

artículo científico publicado en 2015

Characterization of heparin-induced glyceraldehyde-3-phosphate dehydrogenase early amyloid-like oligomers and their implication in α-synuclein aggregation.

artículo científico publicado en 2011

Creutzfeldt-Jakob Disease with a Five-Year Clinical Course, Multicentric Cerebellar Prion Plaques and Prior History of Biopsy-Proven Primary Angiitis of the Central Nervous System: A Case for Iatrogenic Exposure?

scientific article published on 08 December 2020

Creutzfeldt-Jakob disease in pregnancy: the use of modified RT-QuIC to determine infectivity in placental tissues

artículo científico publicado en 2021

D-amino acid-based peptide inhibitors as early or preventative therapy in Alzheimer disease

artículo científico publicado en 2014

Deposition pattern and subcellular distribution of disease-associated prion protein in cerebellar organotypic slice cultures infected with scrapie.

artículo científico publicado en 2015

Dural Reduction Surgery: A Treatment Option for Frontotemporal Brain Sagging Syndrome

artículo científico publicado en 2016

Early increase and late decrease of purkinje cell dendritic spine density in prion-infected organotypic mouse cerebellar cultures

artículo científico publicado en 2013

Effectiveness of multimedia interventions in the provision of patient education on anticoagulation therapy: A review

artículo científico publicado en 2020

Exposure Risk of Chronic Wasting Disease in Humans

artículo científico publicado en 2020

From Cell Culture to Organoids-Model Systems for Investigating Prion Strain Characteristics

artículo científico publicado en 2021

High Dose and Delayed Treatment with Bile Acids Ineffective in RML Prion-Infected Mice

scholarly article by Grant Norman et al published August 2018 in Antimicrobial Agents and Chemotherapy

Implications of prion polymorphisms

artículo científico publicado en 2013

Infectious prions accumulate to high levels in non proliferative C2C12 myotubes.

artículo científico publicado en 2013

Inhibition of adenine nucleotide translocator pore function and protection against apoptosis in vivo by an HIV protease inhibitor

artículo científico publicado en 2005

Molecular heterosis of prion protein beta-oligomers. A potential mechanism of human resistance to disease

scientific article published on 15 September 2006

Mouse prion protein polymorphism Phe-108/Val-189 affects the kinetics of fibril formation and the response to seeding: evidence for a two-step nucleation polymerization mechanism

artículo científico publicado en 2013

Mycobacterium chimaera Encephalitis Following Cardiac Surgery: A New Syndrome

artículo científico publicado en 2020

Native nanodiscs formed by styrene-maleic acid copolymer derivatives help recover infectious prion multimers bound to brain-derived lipids

artículo científico publicado en 2020

Oral administration of repurposed drug targeting Cyp46A1 increases survival times of prion infected mice

artículo científico publicado en 2021

POSCAbilities: The Application of the Prion Organotypic Slice Culture Assay to Neurodegenerative Disease Research

artículo científico publicado en 2020

Pharmacological chaperone reshapes the energy landscape for folding and aggregation of the prion protein

artículo científico publicado en 2016

Prion Disease: Chemotherapeutic Strategies

artículo científico publicado el 1 de abril de 2012

Prion strain-dependent differences in conversion of mutant prion proteins in cell culture

artículo científico publicado en 2006

Quaternary Structure Changes for PrPSc Predate PrPC Downregulation and Neuronal Death During Progression of Experimental Scrapie Disease

artículo científico publicado en 2020

Recent advances in prion chemotherapeutics

artículo científico publicado en 2009

Structure-Based Peptide Design to Modulate Amyloid Beta Aggregation and Reduce Cytotoxicity

artículo científico publicado en 2015

The Effects of N-terminal Mutations on β-amyloid Peptide Aggregation and Toxicity.

artículo científico publicado en 2018

The mechanism of membrane disruption by cytotoxic amyloid oligomers formed by prion protein(106-126) is dependent on bilayer composition.

artículo científico publicado en 2014

The most infectious prion protein particles.

artículo científico publicado en 2005

The therapeutic potential of chemical chaperones in protein folding diseases.

artículo científico

Toll-like receptor-mediated immune response inhibits prion propagation.

artículo científico publicado en 2016

Ultrasensitive detection of scrapie prion protein using seeded conversion of recombinant prion protein

artículo científico publicado en 2007

Ultrastructures and strain comparison of under-glycosylated scrapie prion fibrils

artículo científico publicado en 2008