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A blood pressure genetic risk score is a significant predictor of incident cardiovascular events in 32,669 individuals

artículo científico publicado en 2013

A common variant near the KCNJ2 gene is associated with T-peak to T-end interval

artículo científico publicado en 2012

A meta-analysis of genome-wide association studies of the electrocardiographic early repolarization pattern

artículo científico publicado en 2012

A metabolic view on menopause and ageing

artículo científico publicado en 2014

A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease

scientific article published on 13 April 2020

A multilocus genetic risk score for coronary heart disease: case-control and prospective cohort analyses

artículo científico publicado en 2010

A multiple biomarker risk score for guiding clinical decisions using a decision curve approach

artículo científico publicado en 2011

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

artículo científico publicado en 2016

Adiposity as a cause of cardiovascular disease: a Mendelian randomization study

artículo científico publicado en 2015

Age- and sex-specific causal effects of adiposity on cardiovascular risk factors

artículo científico publicado en 2015

Aging of the population may not lead to an increase in the numbers of acute coronary events: a community surveillance study and modelled forecast of the future

artículo científico publicado en 2013

An interaction map of circulating metabolites, immune gene networks, and their genetic regulation

artículo científico publicado en 2017

Answer to Dr. Sabours letter about our article 'the validity of hospital discharge register data on non-ST-elevation and ST-elevation myocardial infarction in Finland'

artículo científico publicado en 2020

Apolipoproteins and HDL cholesterol do not associate with the risk of future dementia and Alzheimer's disease: the National Finnish population study (FINRISK).

artículo científico publicado en 2016

Are coronary event rates declining slower in women than in men - evidence from two population-based myocardial infarction registers in Finland?

artículo científico publicado en 2007

Assessment of causality of natriuretic peptides and atrial fibrillation and heart failure: a Mendelian randomization study in the FINRISK cohort

artículo científico publicado en 2020

Association Between the Gut Microbiota and Blood Pressure in a Population Cohort of 6953 Individuals

artículo científico publicado en 2020

Association of LIN28B with adult adiposity-related traits in females

artículo científico publicado en 2012

Association of branched-chain amino acids and other circulating metabolites with risk of incident dementia and Alzheimer's disease: A prospective study in eight cohorts

artículo científico publicado en 2018

Associations between circulating metabolites and arterial stiffness

artículo científico publicado en 2020

Bayesian age-period-cohort models with versatile interactions and long-term predictions: mortality and population in Finland 1878-2050.

artículo científico publicado en 2013

Biological, clinical and population relevance of 95 loci for blood lipids

artículo científico publicado en 2010

Biomarker profiling by nuclear magnetic resonance spectroscopy for the prediction of all-cause mortality: an observational study of 17,345 persons

artículo científico publicado en 2014

CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits

artículo científico publicado en 2017

Calcium:magnesium ratio in local groundwater and incidence of acute myocardial infarction among males in rural Finland

artículo científico publicado en 2006

Cardiovascular Risk Factors and Ischemic Heart Disease: Is the Confluence of Risk Factors Greater Than the Parts? A Genetic Approach

artículo científico publicado en 2016

Case fatality of acute coronary events is improving even among elderly patients; the FINAMI study 1995-2012.

artículo científico publicado en 2017

Ceramide stearic to palmitic acid ratio predicts incident diabetes

artículo científico publicado en 2018

Circulating Ceramides Predict Cardiovascular Outcomes in the Population-Based FINRISK 2002 Cohort

artículo científico publicado en 2016

Circulating metabolites and the risk of type 2 diabetes: a prospective study of 11,896 young adults from four Finnish cohorts

Clinical and molecular genetic risk determinants in adult long QT syndrome type 1 and 2 patients : Koponen et al. Follow-up of adult LQTS patients.

artículo científico publicado en 2018

Combined effects of host genetics and diet on human gut microbiota and incident disease in a single population cohort

artículo científico publicado en 2020

Combined effects of host genetics and diet on human gut microbiota and incident disease in a single population cohort

artículo científico publicado en 2022

Common genetic variants associated with sudden cardiac death: the FinSCDgen study

artículo científico publicado en 2012

Common genetic variants, QT interval, and sudden cardiac death in a Finnish population-based study

artículo científico publicado en 2011

Common missense variant in the glucokinase regulatory protein gene is associated with increased plasma triglyceride and C-reactive protein but lower fasting glucose concentrations

artículo científico publicado en 2008

Common variants show predicted polygenic effects on height in the tails of the distribution, except in extremely short individuals

artículo científico publicado en 2011

Comparison of three troponins as predictors of future cardiovascular events--prospective results from the FINRISK and BiomaCaRE studies

artículo científico publicado en 2014

Contribution of 30 biomarkers to 10-year cardiovascular risk estimation in 2 population cohorts: the MONICA, risk, genetics, archiving, and monograph (MORGAM) biomarker project

artículo científico publicado en 2010

Coronary events in persons aged 75 years or older in Finland from 1995 to 2002: the FINAMI study.

artículo científico publicado en 2008

Correction to: Increased plasma N-glycome complexity is associated with higher risk of type 2 diabetes

artículo científico publicado en 2017

Correction: Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution.

artículo científico publicado en 2009

Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

artículo científico publicado en 2017

Correction: Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation

artículo científico publicado en 2019

Decreased mortality risk due to first acute coronary syndrome in women with postmenopausal hormone therapy use.

artículo científico publicado en 2016

Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation

artículo científico publicado en 2015

Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

artículo científico publicado en 2020

Distribution and medical impact of loss-of-function variants in the Finnish founder population

artículo científico publicado en 2014

Does the clinical spectrum of incident cardiovascular disease differ between men and women?

artículo científico publicado en 2013

Effects of hormonal contraception on systemic metabolism: cross-sectional and longitudinal evidence

artículo científico publicado en 2016

Effects of long-term exposure to air pollution on natural-cause mortality: an analysis of 22 European cohorts within the multicentre ESCAPE project

artículo científico publicado en 2013

Endotoxemia Is Associated With an Increased Risk of Incident Diabetes ⬇️

artículo científico publicado el 1 de febrero de 2011

Endotoxemia, immune response to periodontal pathogens, and systemic inflammation associate with incident cardiovascular disease events

scientific article published on 15 March 2007

Erratum: Corrigendum: Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans

scholarly article published in Nature Genetics

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

artículo científico publicado en 2011

Evidence of inbreeding depression on human height

artículo científico publicado en 2012

Experimental and Human Evidence for Lipocalin-2 (Neutrophil Gelatinase-Associated Lipocalin [NGAL]) in the Development of Cardiac Hypertrophy and heart failure

artículo científico publicado en 2017

FINEMAP: efficient variable selection using summary data from genome-wide association studies

artículo científico publicado en 2016

Fine-Scale Genetic Structure in Finland

artículo científico publicado en 2017

Follow-up of 316 molecularly defined pediatric long-QT syndrome patients: clinical course, treatments, and side effects

artículo científico publicado en 2015

Gender differences in the prevalence, causes and treatment of high cardiovascular risk: findings from the FINRISK Survey

artículo científico publicado en 2011

Genetic Variants Contributing to Circulating Matrix Metalloproteinase 8 Levels and Their Association With Cardiovascular Diseases: A Genome-Wide Analysis

artículo científico publicado en 2017

Genetic Variants on Chromosome 1p13.3 Are Associated with Non-ST Elevation Myocardial Infarction and the Expression of DRAM2 in the Finnish Population

artículo científico publicado en 2015

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scientific article published on 17 September 2018

Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Genetic evidence of assortative mating in humans

article

Genetic risk prediction and a 2-stage risk screening strategy for coronary heart disease

artículo científico publicado en 2013

Genetic support for the causal role of insulin in coronary heart disease

artículo científico publicado en 2016

Genetic variants and blood pressure in a population-based cohort: the Cardiovascular Risk in Young Finns study

artículo científico publicado en 2011

Genome-Wide Association Study Implicates Atrial Natriuretic Peptide Rather Than B-Type Natriuretic Peptide in the Regulation of Blood Pressure in the General Population

artículo científico publicado en 2017

Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors

artículo científico publicado en 2016

Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants

artículo científico publicado en 2009

Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution

artículo científico publicado en 2009

Genome-wide association studies with high-dimensional phenotypes

artículo científico publicado en 2013

Genome-wide association study of white-coat effect in hypertensive patients

scientific article published on 02 May 2019

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels

artículo científico publicado en 2016

Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

artículo científico publicado en 2017

Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits

scientific journal article

Genomic prediction of coronary heart disease

artículo científico publicado en 2016

Geographic patterns of incidence of ischemic stroke and acute myocardial infarction in Finland during 1991-2003.

artículo científico publicado en 2008

Geographical variation of medicated parkinsonism in Finland during 1995 to 2000.

artículo científico publicado en 2008

Habitual sleep duration is associated with BMI and macronutrient intake and may be modified by CLOCK genetic variants

artículo científico publicado en 2014

Haplotype Sharing Provides Insights into Fine-Scale Population History and Disease in Finland

scholarly article by Alicia R Martin et al published 3 May 2018 in American Journal of Human Genetics

High-sensitivity cardiac troponin I and NT-proBNP as predictors of incident dementia and Alzheimer's disease: the FINRISK Study

artículo científico publicado en 2016

Hundreds of variants clustered in genomic loci and biological pathways affect human height

artículo científico publicado en 2010

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

artículo científico publicado en 2013

Improving genomics-based predictions for precision medicine through active elicitation of expert knowledge.

artículo científico publicado en 2018

Increased plasma N-glycome complexity is associated with higher risk of type 2 diabetes

artículo científico publicado en 2017

Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies

artículo científico publicado en 2010

Large-scale association analysis identifies new risk loci for coronary artery disease

artículo científico publicado en 2012

Levels of apolipoprotein M are not associated with the risk of coronary heart disease in two independent case-control studies

artículo científico publicado en 2008

Long-term exposure to ambient air pollution and incidence of cerebrovascular events: results from 11 European cohorts within the ESCAPE project

artículo científico publicado en 2014

Low-expression variant of fatty acid-binding protein 4 favors reduced manifestations of atherosclerotic disease and increased plaque stability

artículo científico publicado en 2014

Machine learning of human plasma lipidomes for obesity estimation in a large population cohort

scientific article published on 18 October 2019

Matrix metalloproteinase-8 and tissue inhibitor of matrix metalloproteinase-1 predict incident cardiovascular disease events and all-cause mortality in a population-based cohort

artículo científico publicado en 2017

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

artículo científico publicado en 2010

Metabolic signatures of adiposity in young adults: Mendelian randomization analysis and effects of weight change

artículo científico publicado en 2014

Metabolite profiling and cardiovascular event risk: a prospective study of 3 population-based cohorts

artículo científico publicado en 2015

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction

scientific article published on 21 May 2020

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

artículo científico publicado en 2018

NT-proBNP and the risk of dementia: a prospective cohort study with 14 years of follow-up

artículo científico publicado en 2015

New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals

artículo científico publicado en 2017

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk ⬇️

artículo científico publicado en 2016

Novel 6p21.3 Risk Haplotype Predisposes to Acute Coronary Syndrome

artículo científico

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney

artículo científico publicado en 2017

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

artículo científico publicado en 2012

Nuclear magnetic resonance-based metabolomics identifies phenylalanine as a novel predictor of incident heart failure hospitalisation: results from PROSPER and FINRISK 1997.

artículo científico publicado en 2017

Obstructive sleep apnoea and the risk for coronary heart disease and type 2 diabetes: a longitudinal population-based study in Finland

scientific article published on 15 October 2018

Phylogeny-Aware Analysis of Metagenome Community Ecology Based on Matched Reference Genomes while Bypassing Taxonomy

artículo científico publicado en 2022

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

artículo científico publicado en 2012

Polygenic and clinical risk scores and their impact on age at onset and prediction of cardiometabolic diseases and common cancers

scientific article published on 07 April 2020

Prediction of Blood Pressure and Blood Pressure Change With a Genetic Risk Score.

artículo científico publicado en 2015

Predictive value of electrocardiographic T-wave morphology parameters and T-wave peak to T-wave end interval for sudden cardiac death in the general population

artículo científico publicado en 2013

Predictive value of galectin-3 for incident cardiovascular disease and heart failure in the population-based FINRISK 1997 cohort

artículo científico publicado en 2015

Predictive value of midregional pro-adrenomedullin compared to natriuretic peptides for incident cardiovascular disease and heart failure in the population-based FINRISK 1997 cohort

Prevalence and clinical correlates of familial hypercholesterolemia founder mutations in the general population

artículo científico publicado en 2014

Prevalence of arrhythmia-associated gene mutations and risk of sudden cardiac death in the Finnish population

artículo científico publicado en 2013

Prospects of Fine-Mapping Trait-Associated Genomic Regions by Using Summary Statistics from Genome-wide Association Studies

artículo científico publicado en 2017

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scholarly article published in Nature Genetics

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

erratum

Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

artículo científico publicado en 2019

Quantifying the Impact of Rare and Ultra-rare Coding Variation across the Phenotypic Spectrum

Quantifying the impact of rare and ultra-rare coding variation across the phenotypic spectrum

Rare protein-altering variants in ANGPTL7 lower intraocular pressure and protect against glaucoma

artículo científico publicado en 2020

Risk Factors for Early-Onset Ischemic Stroke: A Case-Control Study

scientific article published on 01 November 2018

ST2 may not be a useful predictor for incident cardiovascular events, heart failure and mortality

artículo científico publicado en 2014

Serum tissue-degrading proteinases and incident cardiovascular disease events

scientific article published on 18 October 2012

Significant interactions between traditional risk factors affect cardiovascular risk prediction in healthy general population

artículo científico publicado en 2014

Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans

artículo científico publicado en 2008

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

artículo científico publicado en 2009

Soluble HLA-DR serum levels are associated with smoking but not with acute coronary syndrome

artículo científico publicado en 2017

Systems medicine links microbial inflammatory response with glycoprotein-associated mortality risk

artículo científico publicado en 2015

Taxonomic signatures of cause-specific mortality risk in human gut microbiome

artículo científico publicado en 2021

The Biomarker GlycA Is Associated with Chronic Inflammation and Predicts Long-Term Risk of Severe Infection

artículo científico publicado en 2015

The effect of LRRK2 loss-of-function variants in humans

artículo científico publicado en 2020

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

artículo científico publicado en 2016

The impact of low-frequency and rare variants on lipid levels

artículo científico publicado en 2015

The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis

artículo científico publicado en 2013

The validity of heart failure diagnoses in the Finnish Hospital Discharge Register

scientific article published on 09 May 2019

The validity of hospital discharge register data on non-ST-elevation and ST-elevation myocardial infarction in Finland

artículo científico publicado en 2019

Thirty-one novel biomarkers as predictors for clinically incident diabetes

artículo científico publicado en 2010

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

artículo científico publicado en 2016

Trends in long-term prognosis after acute coronary syndrome

artículo científico publicado en 2016

Twenty-five-year trends in myocardial infarction attack and mortality rates, and case-fatality, in six European populations

artículo científico publicado en 2015

USF1 deficiency activates brown adipose tissue and improves cardiometabolic health

artículo científico publicado en 2016

Utilizing twins as controls for non-twin case-materials in genome wide association studies

artículo científico publicado en 2013

Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation

article

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