Lista de obras -

A chemically unmodified agonistic DNA with growth factor functionality for in vivo therapeutic application

scientific article published on 01 April 2020

A tadpole-shaped gene carrier with distinct phase segregation in a ternary polymeric micelle

artículo científico publicado en 2015

Acidic pH-responsive siRNA conjugate for reversible carrier stability and accelerated endosomal escape with reduced IFNα-associated immune response.

artículo científico publicado en 2013

An injectable spheroid system with genetic modification for cell transplantation therapy.

artículo científico publicado en 2013

Bundling mRNA Strands to Prepare Nano-Assemblies with Enhanced Stability Towards RNase for In Vivo Delivery

artículo científico publicado en 2019

Bundling of mRNA strands inside polyion complexes improves mRNA delivery efficiency in vitro and in vivo

artículo científico publicado en 2020

Combination of chondroitin sulfate and polyplex micelles from Poly(ethylene glycol)-poly{N’-[N-(2-aminoethyl)-2-aminoethyl]aspartamide} block copolymer for prolonged in vivo gene transfection with reduced toxicity ⬇️

artículo científico publicado el 5 de mayo de 2011

Design concepts of polyplex micelles for in vivo therapeutic delivery of plasmid DNA and messenger RNA

scientific article published on 31 January 2019

Designing immunostimulatory double stranded messenger RNA with maintained translational activity through hybridization with poly A sequences for effective vaccination.

artículo científico publicado en 2017

Development of Biodegradable Polycation-Based Inhalable Dry Gene Powders by Spray Freeze Drying

artículo científico publicado en 2015

Enhancement of Motor Function Recovery after Spinal Cord Injury in Mice by Delivery of Brain-Derived Neurotrophic Factor mRNA

artículo científico publicado en 2019

Gene Transfection toward Spheroid Cells on Micropatterned Culture Plates for Genetically-modified Cell Transplantation.

artículo científico publicado en 2015

Gene transfection to spheroid culture system on micropatterned culture plate by polyplex nanomicelle: a novel platform of genetically-modified cell transplantation

artículo científico publicado en 2012

Glycaemic control boosts glucosylated nanocarrier crossing the BBB into the brain

artículo científico publicado en 2017

Homo-catiomer integration into PEGylated polyplex micelle from block-catiomer for systemic anti-angiogenic gene therapy for fibrotic pancreatic tumors.

artículo científico publicado en 2012

In vivo messenger RNA introduction into the central nervous system using polyplex nanomicelle

artículo científico publicado en 2013

Induced packaging of mRNA into polyplex micelles by regulated hybridization with a small number of cholesteryl RNA oligonucleotides directed enhanced in vivo transfection

scientific article published on 17 January 2019

Intrathecal injection of a therapeutic gene-containing polyplex to treat spinal cord injury

artículo científico publicado en 2014

Messenger RNA-based therapeutics for brain diseases: An animal study for augmenting clearance of beta-amyloid by intracerebral administration of neprilysin mRNA loaded in polyplex nanomicelles.

artículo científico publicado en 2016

Messenger RNA-based therapeutics for the treatment of apoptosis-associated diseases

artículo científico publicado en 2015

Muscle-targeted hydrodynamic gene introduction of insulin-like growth factor-1 using polyplex nanomicelle to treat peripheral nerve injury.

artículo científico publicado en 2014

Optimized rod length of polyplex micelles for maximizing transfection efficiency and their performance in systemic gene therapy against stroma-rich pancreatic tumors.

artículo científico publicado en 2014

PEG-OligoRNA Hybridization of mRNA for Developing Sterically Stable Lipid Nanoparticles toward In Vivo Administration

artículo científico publicado en 2019

PEGylated Polyplex With Optimized PEG Shielding Enhances Gene Introduction in Lungs by Minimizing Inflammatory Responses ⬇️

artículo científico publicado el 14 de febrero de 2012

Polyplex Micelles with Phenylboronate/Gluconamide Cross-Linking in the Core Exerting Promoted Gene Transfection through Spatiotemporal Responsivity to Intracellular pH and ATP Concentration.

artículo científico publicado en 2017

Polyplex micelle installing intracellular self-processing functionalities without free catiomers for safe and efficient systemic gene therapy through tumor vasculature targeting

artículo científico publicado en 2016

Precise tuning of disulphide crosslinking in mRNA polyplex micelles for optimising extracellular and intracellular nuclease tolerability

scientific article published on 05 April 2019

Prolonged engraftment of transplanted hepatocytes in the liver by transient pro-survival factor supplementation using ex vivo mRNA transfection

artículo científico publicado en 2018

Screening of mRNA Chemical Modification to Maximize Protein Expression with Reduced Immunogenicity.

artículo científico publicado en 2015

Single-Stranded DNA-Packaged Polyplex Micelle as Adeno-Associated-Virus-Inspired Compact Vector to Systemically Target Stroma-Rich Pancreatic Cancer

artículo científico publicado en 2019

Systemic Delivery of Folate-PEG siRNA Lipopolyplexes with Enhanced Intracellular Stability for In Vivo Gene Silencing in Leukemia

artículo científico publicado en 2017

Targeted gene delivery by polyplex micelles with crowded PEG palisade and cRGD moiety for systemic treatment of pancreatic tumors

artículo científico publicado en 2014

Toroidal Packaging of pDNA into Block Ionomer Micelles Exerting Promoted in Vivo Gene Expression.

artículo científico publicado en 2015

Transient stealth coating of liver sinusoidal wall by anchoring two-armed PEG for retargeting nanomedicines

artículo científico publicado en 2020

Treatment of Bone Defects by Transplantation of Genetically Modified Mesenchymal Stem Cell Spheroids

scientific article published on 18 April 2018

Treatment of Intervertebral Disk Disease by the Administration of mRNA Encoding a Cartilage-Anabolic Transcription Factor

scientific article published on 22 February 2019

Treatment of spinal cord injury by an advanced cell transplantation technology using brain-derived neurotrophic factor-transfected mesenchymal stem cell spheroids.

artículo científico publicado en 2016

Tunable nonenzymatic degradability of N-substituted polyaspartamide main chain by amine protonation and alkyl spacer length in side chains for enhanced messenger RNA transfection efficiency

scientific article published on 13 February 2019

mRNA as a Tool for Gene Transfection in 3D Cell Culture for Future Regenerative Therapy

artículo científico publicado en 2020

Lista de obras de

A chemically unmodified agonistic DNA with growth factor functionality for in vivo therapeutic application

A tadpole-shaped gene carrier with distinct phase segregation in a ternary polymeric micelle

Acidic pH-responsive siRNA conjugate for reversible carrier stability and accelerated endosomal escape with reduced IFNα-associated immune response.

An injectable spheroid system with genetic modification for cell transplantation therapy.

Bundling mRNA Strands to Prepare Nano-Assemblies with Enhanced Stability Towards RNase for In Vivo Delivery

Bundling of mRNA strands inside polyion complexes improves mRNA delivery efficiency in vitro and in vivo

Combination of chondroitin sulfate and polyplex micelles from Poly(ethylene glycol)-poly{N’-[N-(2-aminoethyl)-2-aminoethyl]aspartamide} block copolymer for prolonged in vivo gene transfection with reduced toxicity ⬇️

Design concepts of polyplex micelles for in vivo therapeutic delivery of plasmid DNA and messenger RNA

Designing immunostimulatory double stranded messenger RNA with maintained translational activity through hybridization with poly A sequences for effective vaccination.

Development of Biodegradable Polycation-Based Inhalable Dry Gene Powders by Spray Freeze Drying

Enhancement of Motor Function Recovery after Spinal Cord Injury in Mice by Delivery of Brain-Derived Neurotrophic Factor mRNA

Gene Transfection toward Spheroid Cells on Micropatterned Culture Plates for Genetically-modified Cell Transplantation.

Gene transfection to spheroid culture system on micropatterned culture plate by polyplex nanomicelle: a novel platform of genetically-modified cell transplantation

Glycaemic control boosts glucosylated nanocarrier crossing the BBB into the brain

Homo-catiomer integration into PEGylated polyplex micelle from block-catiomer for systemic anti-angiogenic gene therapy for fibrotic pancreatic tumors.

In vivo messenger RNA introduction into the central nervous system using polyplex nanomicelle

Induced packaging of mRNA into polyplex micelles by regulated hybridization with a small number of cholesteryl RNA oligonucleotides directed enhanced in vivo transfection

Intrathecal injection of a therapeutic gene-containing polyplex to treat spinal cord injury

Messenger RNA-based therapeutics for brain diseases: An animal study for augmenting clearance of beta-amyloid by intracerebral administration of neprilysin mRNA loaded in polyplex nanomicelles.

Messenger RNA-based therapeutics for the treatment of apoptosis-associated diseases

Muscle-targeted hydrodynamic gene introduction of insulin-like growth factor-1 using polyplex nanomicelle to treat peripheral nerve injury.

Optimized rod length of polyplex micelles for maximizing transfection efficiency and their performance in systemic gene therapy against stroma-rich pancreatic tumors.

PEG-OligoRNA Hybridization of mRNA for Developing Sterically Stable Lipid Nanoparticles toward In Vivo Administration

PEGylated Polyplex With Optimized PEG Shielding Enhances Gene Introduction in Lungs by Minimizing Inflammatory Responses ⬇️

Polyplex Micelles with Phenylboronate/Gluconamide Cross-Linking in the Core Exerting Promoted Gene Transfection through Spatiotemporal Responsivity to Intracellular pH and ATP Concentration.

Polyplex micelle installing intracellular self-processing functionalities without free catiomers for safe and efficient systemic gene therapy through tumor vasculature targeting

Precise tuning of disulphide crosslinking in mRNA polyplex micelles for optimising extracellular and intracellular nuclease tolerability

Prolonged engraftment of transplanted hepatocytes in the liver by transient pro-survival factor supplementation using ex vivo mRNA transfection

Screening of mRNA Chemical Modification to Maximize Protein Expression with Reduced Immunogenicity.

Single-Stranded DNA-Packaged Polyplex Micelle as Adeno-Associated-Virus-Inspired Compact Vector to Systemically Target Stroma-Rich Pancreatic Cancer

Systemic Delivery of Folate-PEG siRNA Lipopolyplexes with Enhanced Intracellular Stability for In Vivo Gene Silencing in Leukemia

Targeted gene delivery by polyplex micelles with crowded PEG palisade and cRGD moiety for systemic treatment of pancreatic tumors

Toroidal Packaging of pDNA into Block Ionomer Micelles Exerting Promoted in Vivo Gene Expression.

Transient stealth coating of liver sinusoidal wall by anchoring two-armed PEG for retargeting nanomedicines

Treatment of Bone Defects by Transplantation of Genetically Modified Mesenchymal Stem Cell Spheroids

Treatment of Intervertebral Disk Disease by the Administration of mRNA Encoding a Cartilage-Anabolic Transcription Factor

Treatment of spinal cord injury by an advanced cell transplantation technology using brain-derived neurotrophic factor-transfected mesenchymal stem cell spheroids.

Tunable nonenzymatic degradability of N-substituted polyaspartamide main chain by amine protonation and alkyl spacer length in side chains for enhanced messenger RNA transfection efficiency

mRNA as a Tool for Gene Transfection in 3D Cell Culture for Future Regenerative Therapy