Lista de obras - Kay L Double - Dominio Público Uruguay

A Proposed Mechanism for Neurodegeneration in Movement Disorders Characterized by Metal Dyshomeostasis and Oxidative Stress

artículo científico publicado en 2018

A53T-alpha-synuclein overexpression impairs dopamine signaling and striatal synaptic plasticity in old mice

artículo científico publicado en 2010

Accumulation of dysfunctional SOD1 protein in Parkinson's disease is not associated with mutations in the SOD1 gene.

artículo científico publicado en 2017

Alpha-synuclein redistributes to neuromelanin lipid in the substantia nigra early in Parkinson's disease.

artículo científico publicado en 2005

Amyotrophic lateral sclerosis-like superoxide dismutase 1 proteinopathy is associated with neuronal loss in Parkinson's disease brain

artículo científico publicado en 2017

Analogues of desferrioxamine B designed to attenuate iron-mediated neurodegeneration: synthesis, characterisation and activity in the MPTP-mouse model of Parkinson's disease

artículo científico publicado en 2017

Arguments for the use of dopamine receptor agonists in clinical and preclinical Parkinson's disease

artículo científico publicado en 2003

Brain iron pathways and their relevance to Parkinson's disease.

artículo científico publicado en 2001

Cell loss in the nucleus basalis is related to regional cortical atrophy in Alzheimer's disease.

artículo científico publicado en 1997

Comparative Study of Metal Quantification in Neurological Tissue Using Laser Ablation-Inductively Coupled Plasma-Mass Spectrometry Imaging and X-ray Fluorescence Microscopy

artículo científico publicado en 2015

Copper dyshomoeostasis in Parkinson's disease: implications for pathogenesis and indications for novel therapeutics

artículo científico publicado en 2016

Copper pathology in vulnerable brain regions in Parkinson's disease

artículo científico publicado en 2013

Decline in Proliferation and Immature Neuron Markers in the Human Subependymal Zone during Aging: Relationship to EGF- and FGF-Related Transcripts

artículo científico publicado en 2016

Differential effects of human neuromelanin and synthetic dopamine melanin on neuronal and glial cells.

artículo científico publicado en 2005

Dolichol is the major lipid component of human substantia nigra neuromelanin.

artículo científico publicado en 2005

Dopamine receptor agonists in current clinical use: comparative dopamine receptor binding profiles defined in the human striatum

artículo científico publicado en 2003

Dopamine receptor agonists in the therapy of Parkinson's disease.

artículo científico publicado en 2003

Dopamine receptors in the substantia nigra are involved in the regulation of muscle tone.

artículo científico publicado en 1995

Effect of age on proliferation-regulating factors in human adult neurogenic regions

scientific article published on 28 September 2010

Effects of inactivation of D1 dopamine receptors on stereotypic and thermic responses to quinpirole (LY 171555).

artículo científico publicado en 1990

Endogenous progesterone levels and frontotemporal dementia: modulation of TDP-43 and Tau levels in vitro and treatment of the A315T TARDBP mouse model.

artículo científico publicado en 2013

Evidence for reduced neurogenesis in the aging human hippocampus despite stable stem cell markers.

artículo científico publicado en 2017

Evidence for specific phases in the development of human neuromelanin

article

Evidence for specific phases in the development of human neuromelanin.

artículo científico publicado en 2006

Expression of stereotyped behaviour requires stimulation of nigral D1 dopamine receptors.

artículo científico publicado en 1995

Functional effects of neuromelanin and synthetic melanin in model systems.

artículo científico publicado en 2006

GIRK2 expression in dopamine neurons of the substantia nigra and ventral tegmental area.

artículo científico publicado en 2012

Hand function is impaired in healthy older adults at risk of Parkinson's disease

artículo científico publicado en 2014

Hippocampal Lewy pathology and cholinergic dysfunction are associated with dementia in Parkinson's disease.

artículo científico publicado en 2014

Identifying severely atrophic cortical subregions in Alzheimer's disease.

artículo científico publicado en 2003

Identifying the pattern of olfactory deficits in Parkinson disease using the brief smell identification test

artículo científico publicado en 2003

Impaired iron homeostasis in Parkinson's disease.

artículo científico publicado en 2000

In vitro studies of ferritin iron release and neurotoxicity.

artículo científico publicado en 1998

Influence of neuromelanin on oxidative pathways within the human substantia nigra

artículo científico publicado en 2002

Intracellular chemical imaging of the developmental phases of human neuromelanin using synchrotron X-ray microspectroscopy.

artículo científico publicado en 2008

Investigation of the lipid component of neuromelanin.

artículo científico publicado en 2006

Iron and dopamine: a toxic couple.

artículo científico publicado en 2016

Iron in the Parkinsonian substantia nigra.

artículo científico publicado en 1997

Iron-binding characteristics of neuromelanin of the human substantia nigra.

artículo científico publicado en 2003

Language-associated cortical regions are proportionally larger in the female brain

artículo científico publicado en 1997

Levels of glial cell line-derived neurotrophic factor are decreased, but fibroblast growth factor 2 and cerebral dopamine neurotrophic factor are increased in the hippocampus in Parkinson's disease

artículo científico publicado en 2019

Localization of copper and copper transporters in the human brain.

artículo científico publicado en 2013

Low Serum Progranulin Predicts the Presence of Mutations: A Prospective Study

scientific article published on 01 January 2010

Meta-Analysis of Copper and Iron in Parkinson's Disease Brain and Biofluids

scientific article published on 31 December 2019

Neural degeneration in Parkinson's disease.

artículo científico publicado en 2001

Neuromelanin and its interaction with iron as a potential risk factor for dopaminergic neurodegeneration underlying Parkinson's disease

artículo científico publicado en 2003

Neuromelanin in human dopamine neurons: Comparison with peripheral melanins and relevance to Parkinson's disease

artículo científico publicado en 2005

Neuromelanin-bound ferric iron as an experimental model of dopaminergic neurodegeneration in Parkinson's disease.

artículo científico publicado en 2008

Neuronal vulnerability in Parkinson's disease.

artículo científico

New face of neuromelanin.

artículo científico publicado en 2006

Oxidative stress in the aging substantia nigra and the etiology of Parkinson's disease

scientific article published on 20 August 2019

Pathophysiology of transcranial sonography signal changes in the human substantia nigra.

artículo científico publicado en 2010

Pigmentation in the human brain and risk of Parkinson's disease.

artículo científico publicado en 2010

Potential sources of increased iron in the substantia nigra of parkinsonian patients

artículo científico publicado en 2006

Putative presynaptic dopamine dysregulation in schizophrenia is supported by molecular evidence from post-mortem human midbrain

artículo científico publicado en 2017

Quantitative electromyographic changes following modification of central dopaminergic transmission.

artículo científico publicado en 1993

Reducing the burden of neurological disease and mental illness

artículo científico publicado en 2017

Reduction in IGF1 mRNA in the Human Subependymal Zone During Aging

artículo científico publicado en 2019

Regional brain atrophy in idiopathic parkinson's disease and diffuse Lewy body disease

artículo científico publicado en 1996

Regional specificity of brain atrophy in Huntington's disease.

artículo científico publicado en 1998

Role of iron in 6-hydroxydopamine neurotoxicity

artículo científico publicado en 1999

Simultaneous structural and elemental nano-imaging of human brain tissue

artículo científico publicado en 2020

Strategies for the protection of dopaminergic neurons against neurotoxicity.

artículo científico publicado en 2000

Structural Characteristics of Human Substantia Nigra Neuromelanin and Synthetic Dopamine Melanins

artículo científico publicado en 2000

Subcellular compartmentalisation of copper, iron, manganese, and zinc in the Parkinson's disease brain.

artículo científico publicado en 2017

Substantia nigra echomorphology and motor cortex excitability.

artículo científico publicado en 2010

Substantia nigra echomorphology in the healthy very old: Correlation with motor slowing.

artículo científico publicado en 2006

Tension-referenced measures of gastrocnemius slack length and stiffness in Parkinson's disease.

artículo científico publicado en 2016

Testosterone induces molecular changes in dopamine signaling pathway molecules in the adolescent male rat nigrostriatal pathway

artículo científico publicado en 2014

Testosterone regulation of sex steroid-related mRNAs and dopamine-related mRNAs in adolescent male rat substantia nigra

artículo científico publicado en 2012

The industrial chemical Tinuvin 123 does not induce dopaminergic neurotoxicity in C57Bl/6 mice

artículo científico publicado en 2000

The relevance of iron in the pathogenesis of Parkinson's disease.

artículo científico publicado en 2004

Topography of brain atrophy during normal aging and Alzheimer's disease.

artículo científico publicado en 1996

Trophic factors differentiate dopamine neurons vulnerable to Parkinson's disease.

artículo científico publicado en 2012

Upper limb function is normal in patients with restless legs syndrome (Willis-Ekbom Disease).

artículo científico publicado en 2014

Using Sepia melanin as a PD model to describe the binding characteristics of neuromelanin - A critical review

artículo científico publicado en 2015

Variability in neuronal expression of dopamine receptors and transporters in the substantia nigra

artículo científico publicado en 2013

White matter loss in healthy ageing: A postmortem analysis

scientific article published on 20 February 2008

Lista de obras de Kay L Double

A Proposed Mechanism for Neurodegeneration in Movement Disorders Characterized by Metal Dyshomeostasis and Oxidative Stress

A53T-alpha-synuclein overexpression impairs dopamine signaling and striatal synaptic plasticity in old mice

Accumulation of dysfunctional SOD1 protein in Parkinson's disease is not associated with mutations in the SOD1 gene.

Alpha-synuclein redistributes to neuromelanin lipid in the substantia nigra early in Parkinson's disease.

Amyotrophic lateral sclerosis-like superoxide dismutase 1 proteinopathy is associated with neuronal loss in Parkinson's disease brain

Analogues of desferrioxamine B designed to attenuate iron-mediated neurodegeneration: synthesis, characterisation and activity in the MPTP-mouse model of Parkinson's disease

Arguments for the use of dopamine receptor agonists in clinical and preclinical Parkinson's disease

Brain iron pathways and their relevance to Parkinson's disease.

Cell loss in the nucleus basalis is related to regional cortical atrophy in Alzheimer's disease.

Comparative Study of Metal Quantification in Neurological Tissue Using Laser Ablation-Inductively Coupled Plasma-Mass Spectrometry Imaging and X-ray Fluorescence Microscopy

Copper dyshomoeostasis in Parkinson's disease: implications for pathogenesis and indications for novel therapeutics

Copper pathology in vulnerable brain regions in Parkinson's disease

Decline in Proliferation and Immature Neuron Markers in the Human Subependymal Zone during Aging: Relationship to EGF- and FGF-Related Transcripts

Differential effects of human neuromelanin and synthetic dopamine melanin on neuronal and glial cells.

Dolichol is the major lipid component of human substantia nigra neuromelanin.

Dopamine receptor agonists in current clinical use: comparative dopamine receptor binding profiles defined in the human striatum

Dopamine receptor agonists in the therapy of Parkinson's disease.

Dopamine receptors in the substantia nigra are involved in the regulation of muscle tone.

Effect of age on proliferation-regulating factors in human adult neurogenic regions

Effects of inactivation of D1 dopamine receptors on stereotypic and thermic responses to quinpirole (LY 171555).

Endogenous progesterone levels and frontotemporal dementia: modulation of TDP-43 and Tau levels in vitro and treatment of the A315T TARDBP mouse model.

Evidence for reduced neurogenesis in the aging human hippocampus despite stable stem cell markers.

Evidence for specific phases in the development of human neuromelanin

Evidence for specific phases in the development of human neuromelanin.

Expression of stereotyped behaviour requires stimulation of nigral D1 dopamine receptors.

Functional effects of neuromelanin and synthetic melanin in model systems.

GIRK2 expression in dopamine neurons of the substantia nigra and ventral tegmental area.

Hand function is impaired in healthy older adults at risk of Parkinson's disease

Hippocampal Lewy pathology and cholinergic dysfunction are associated with dementia in Parkinson's disease.

Identifying severely atrophic cortical subregions in Alzheimer's disease.

Identifying the pattern of olfactory deficits in Parkinson disease using the brief smell identification test

Impaired iron homeostasis in Parkinson's disease.

In vitro studies of ferritin iron release and neurotoxicity.

Influence of neuromelanin on oxidative pathways within the human substantia nigra

Intracellular chemical imaging of the developmental phases of human neuromelanin using synchrotron X-ray microspectroscopy.

Investigation of the lipid component of neuromelanin.

Iron and dopamine: a toxic couple.

Iron in the Parkinsonian substantia nigra.

Iron-binding characteristics of neuromelanin of the human substantia nigra.

Language-associated cortical regions are proportionally larger in the female brain

Levels of glial cell line-derived neurotrophic factor are decreased, but fibroblast growth factor 2 and cerebral dopamine neurotrophic factor are increased in the hippocampus in Parkinson's disease

Localization of copper and copper transporters in the human brain.

Low Serum Progranulin Predicts the Presence of Mutations: A Prospective Study

Meta-Analysis of Copper and Iron in Parkinson's Disease Brain and Biofluids

Neural degeneration in Parkinson's disease.

Neuromelanin and its interaction with iron as a potential risk factor for dopaminergic neurodegeneration underlying Parkinson's disease

Neuromelanin in human dopamine neurons: Comparison with peripheral melanins and relevance to Parkinson's disease

Neuromelanin-bound ferric iron as an experimental model of dopaminergic neurodegeneration in Parkinson's disease.

Neuronal vulnerability in Parkinson's disease.

New face of neuromelanin.

Oxidative stress in the aging substantia nigra and the etiology of Parkinson's disease

Pathophysiology of transcranial sonography signal changes in the human substantia nigra.

Pigmentation in the human brain and risk of Parkinson's disease.

Potential sources of increased iron in the substantia nigra of parkinsonian patients

Putative presynaptic dopamine dysregulation in schizophrenia is supported by molecular evidence from post-mortem human midbrain

Quantitative electromyographic changes following modification of central dopaminergic transmission.

Reducing the burden of neurological disease and mental illness

Reduction in IGF1 mRNA in the Human Subependymal Zone During Aging

Regional brain atrophy in idiopathic parkinson's disease and diffuse Lewy body disease

Regional specificity of brain atrophy in Huntington's disease.

Role of iron in 6-hydroxydopamine neurotoxicity

Simultaneous structural and elemental nano-imaging of human brain tissue

Strategies for the protection of dopaminergic neurons against neurotoxicity.

Structural Characteristics of Human Substantia Nigra Neuromelanin and Synthetic Dopamine Melanins

Subcellular compartmentalisation of copper, iron, manganese, and zinc in the Parkinson's disease brain.

Substantia nigra echomorphology and motor cortex excitability.

Substantia nigra echomorphology in the healthy very old: Correlation with motor slowing.

Tension-referenced measures of gastrocnemius slack length and stiffness in Parkinson's disease.

Testosterone induces molecular changes in dopamine signaling pathway molecules in the adolescent male rat nigrostriatal pathway

Testosterone regulation of sex steroid-related mRNAs and dopamine-related mRNAs in adolescent male rat substantia nigra

The industrial chemical Tinuvin 123 does not induce dopaminergic neurotoxicity in C57Bl/6 mice

The relevance of iron in the pathogenesis of Parkinson's disease.

Topography of brain atrophy during normal aging and Alzheimer's disease.

Trophic factors differentiate dopamine neurons vulnerable to Parkinson's disease.

Upper limb function is normal in patients with restless legs syndrome (Willis-Ekbom Disease).

Using Sepia melanin as a PD model to describe the binding characteristics of neuromelanin - A critical review

Variability in neuronal expression of dopamine receptors and transporters in the substantia nigra

White matter loss in healthy ageing: A postmortem analysis