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Lista de obras de Rob C Roovers

A biparatopic anti-EGFR nanobody efficiently inhibits solid tumour growth.

artículo científico publicado en 2011

A bispecific nanobody approach to leverage the potent and widely applicable tumor cytolytic capacity of Vγ9Vδ2-T cells.

artículo científico publicado en 2017

Antibody phage display technology and its applications.

artículo científico publicado en 1998

Camelid Ig V genes reveal significant human homology not seen in therapeutic target genes, providing for a powerful therapeutic antibody platform.

artículo científico publicado en 2015

Combining somatic mutations present in different in vivo affinity-matured antibodies isolated from immunized Lama glama yields ultra-potent antibody therapeutics.

artículo científico publicado en 2016

Construction and characterization of a bispecific diabody for retargeting T cells to human carcinomas

artículo científico publicado en 1998

Crosstalk between epidermal growth factor receptor- and insulin-like growth factor-1 receptor signaling: implications for cancer therapy.

artículo científico publicado en 2009

Downregulation of EGFR by a novel multivalent nanobody-liposome platform.

artículo científico publicado en 2010

Endocytosis of EGFR requires its kinase activity and N-terminal transmembrane dimerization motif.

artículo científico publicado en 2013

Facile labelling of an anti-epidermal growth factor receptor Nanobody with 68Ga via a novel bifunctional desferal chelate for immuno-PET ⬇️

artículo científico publicado el 6 de enero de 2011

High-affinity recombinant phage antibodies to the pan-carcinoma marker epithelial glycoprotein-2 for tumour targeting.

artículo científico publicado en 1998

Highly specific and potently activating Vγ9Vδ2-T cell specific nanobodies for diagnostic and therapeutic applications.

artículo científico publicado en 2016

Human anti-CD30 recombinant antibodies by guided phage antibody selection using cell panning.

artículo científico publicado en 2000

Identification of colon tumour-associated antigens by phage antibody selections on primary colorectal carcinoma

scientific article published on 01 March 2001

In vitro characterisation of a monovalent and bivalent form of a fully human anti Ep-CAM phage antibody.

artículo científico publicado en 2001

MCLA-117, a CLEC12AxCD3 bispecific antibody targeting a leukaemic stem cell antigen, induces T cell-mediated AML blast lysis

scientific article published on 01 July 2019

Nanobodies in therapeutic applications.

artículo científico publicado en 2007

Rapid visualization of human tumor xenografts through optical imaging with a near-infrared fluorescent anti-epidermal growth factor receptor nanobody.

artículo científico publicado en 2012

Regulation of Tiam1-Rac signalling.

artículo científico publicado en 2003

Selection and characterization of KDEL-specific VHH antibody fragments and their application in the study of ER resident protein expression

artículo científico publicado en 2008

Site-specific conjugation of single domain antibodies to liposomes enhances photosensitizer uptake and photodynamic therapy efficacy.

artículo científico publicado en 2016

Structural Evaluation of EGFR Inhibition Mechanisms for Nanobodies/VHH Domains

artículo científico publicado en 2013

Targeting hepatocyte growth factor receptor (Met) positive tumor cells using internalizing nanobody-decorated albumin nanoparticles.

artículo científico publicado en 2013

Therapeutic stem cells expressing variants of EGFR-specific nanobodies have antitumor effects.

artículo científico publicado en 2012

Ubiquilin recruits Eps15 into ubiquitin-rich cytoplasmic aggregates via a UIM-UBL interaction

artículo científico publicado en 2005

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