Lista de obras - Flavio Rizzolio - Dominio Público Uruguay

4-Aryliden-2-methyloxazol-5(4H)-one as a new scaffold for selective reversible MAGL inhibitors

artículo científico publicado en 2015

A Guide to PIN1 Function and Mutations Across Cancers

artículo científico publicado en 2018

A functional biological network centered on XRCC3: a new possible marker of chemoradiotherapy resistance in rectal cancer patients

artículo científico publicado en 2015

A patent review of Monoacylglycerol Lipase (MAGL) inhibitors (2013-2017).

artículo científico publicado en 2017

A susceptibility gene for premature ovarian failure (POF) maps to proximal Xq28

artículo científico publicado en 2004

Alterations of the Plasma Peptidome Profiling in Colorectal Cancer Progression.

artículo científico publicado en 2015

An Effective Multi-Stage Liposomal DNA Origami Nanosystem for In Vivo Cancer Therapy

scientific article published on 12 December 2019

An integrative approach for the identification of prognostic and predictive biomarkers in rectal cancer

artículo científico publicado en 2015

An updated patent review of monoacylglycerol lipase (MAGL) inhibitors (2018-present)

scientific article published on 21 October 2020

Androgen receptor serine 81 mediates Pin1 interaction and activity

artículo científico publicado en 2012

Application of MM-PBSA Methods in Virtual Screening

artículo científico publicado en 2020

Binding investigation and preliminary optimisation of the 3-amino-1,2,4-triazin-5(2H)-one core for the development of new Fyn inhibitors.

artículo científico publicado en 2018

Bottom-up synthesis of carbon nanoparticles with higher doxorubicin efficacy.

artículo científico publicado en 2017

CDK inhibitors: from the bench to clinical trials.

artículo científico publicado en 2010

Cancer Extracellular Vesicles: Next-Generation Diagnostic and Drug Delivery Nanotools

artículo científico publicado en 2020

Carbon Dots from Sugars and Ascorbic Acid: Role of the Precursors on Morphology, Properties, Toxicity, and Drug Uptake

scientific article published on 16 July 2018

Characterization of the Saffron Derivative Crocetin as an Inhibitor of Human Lactate Dehydrogenase 5 in the Antiglycolytic Approach against Cancer.

artículo científico publicado en 2017

Chromosomal rearrangements in Xq and premature ovarian failure: mapping of 25 new cases and review of the literature.

artículo científico publicado en 2006

Clinical predictive circulating peptides in rectal cancer patients treated with neoadjuvant chemoradiotherapy

artículo científico publicado en 2015

Combined effects of PI3K and SRC kinase inhibitors with imatinib on intracellular calcium levels, autophagy, and apoptosis in CML-PBL cells.

artículo científico publicado en 2013

Computationally driven discovery of phenyl(piperazin-1-yl)methanone derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors

artículo científico publicado en 2019

Corrigendum to “Fluorescent molecularly imprinted nanogels for the detection of anticancer drugs in human plasma” [Biosens. Bioelectron. 86 (2016) 913–919]

scientific article published on 23 March 2017

Critical choices for modeling breast cancer in transgenic mouse models.

artículo científico publicado en 2012

Cyclic Ketoximes as Estrogen Receptor β Selective Agonists.

artículo científico publicado en 2016

DNA Nanotechnology for Cancer Therapy

artículo científico publicado en 2016

Decellularized colorectal cancer matrix as bioactive microenvironment for in vitro 3D cancer research

artículo científico publicado en 2017

Development of terphenyl-2-methyloxazol-5(4H)-one derivatives as selective reversible MAGL inhibitors.

artículo científico publicado en 2017

Discovery of 1,5-Diphenylpyrazole-3-Carboxamide Derivatives as Potent, Reversible, and Selective Monoacylglycerol Lipase (MAGL) Inhibitors.

artículo científico publicado en 2018

Discovery of a new ATP-citrate lyase (ACLY) inhibitor identified by a pharmacophore-based virtual screening study

artículo científico publicado en 2020

Discovery of long-chain salicylketoxime derivatives as monoacylglycerol lipase (MAGL) inhibitors

scientific article published on 16 August 2018

Dissecting Pin1 and phospho-pRb regulation.

artículo científico publicado en 2013

Editorial: Peptidyl-Prolyl Isomerases in Human Pathologies

artículo científico publicado en 2019

Emerging molecular networks in Burkitt's lymphoma.

artículo científico

Enhanced Chemotherapeutic Behavior of Open-Caged DNA@Doxorubicin Nanostructures for Cancer Cells

artículo científico publicado en 2015

Epigenetic control of the critical region for premature ovarian failure on autosomal genes translocated to the X chromosome: a hypothesis.

artículo científico publicado en 2007

Exosomal doxorubicin reduces the cardiac toxicity of doxorubicin

artículo científico publicado en 2015

Exosomes increase the therapeutic index of doxorubicin in breast and ovarian cancer mouse models.

artículo científico publicado en 2016

Extracellular Matrix and Colorectal Cancer: How Surrounding Microenvironment Affects Cancer Cell Behavior?

artículo científico publicado en 2016

First-of-its-kind STARD3 Inhibitor: In Silico Identification and Biological Evaluation as Anticancer Agent

scientific article published on 20 February 2019

Fluorescent Carbon Nanoparticles in Medicine for Cancer Therapy: An Update.

artículo científico publicado en 2017

Fluorescent carbon nanoparticles in medicine for cancer therapy

artículo científico publicado en 2013

Fluorescent molecularly imprinted nanogels for the detection of anticancer drugs in human plasma

artículo científico publicado en 2016

Gene and MicroRNA Expression Are Predictive of Tumor Response in Rectal Adenocarcinoma Patients Treated With Preoperative Chemoradiotherapy.

artículo científico

Highly conserved non-coding sequences and the 18q critical region for short stature: a common mechanism of disease?

artículo científico publicado en 2008

Highly selective salicylketoxime-based estrogen receptor β agonists display antiproliferative activities in a glioma model

artículo científico publicado en 2015

Hyaluronan esters drive Smad gene expression and signaling enhancing cardiogenesis in mouse embryonic and human mesenchymal stem cells

artículo científico publicado en 2010

Identification and characterization of a new reversible MAGL inhibitor

artículo científico publicado en 2014

Identification of new Fyn kinase inhibitors using a FLAP-based approach.

artículo científico publicado en 2013

Impact of DNA repair gene polymorphisms on the risk of biochemical recurrence after radiotherapy and overall survival in prostate cancer

artículo científico publicado en 2017

Inorganic Nanoparticles for Cancer Therapy: A Transition from Lab to Clinic

artículo científico publicado en 2018

Liposomal delivery of a Pin1 inhibitor complexed with cyclodextrins as new therapy for high-grade serous ovarian cancer

scientific article published on 08 May 2018

MTHFR-1298 A>C (rs1801131) is a predictor of survival in two cohorts of stage II/III colorectal cancer patients treated with adjuvant fluoropyrimidine chemotherapy with or without oxaliplatin

artículo científico publicado en 2014

Metabolomics biomarkers of frailty in elderly breast cancer patients.

artículo científico publicado en 2014

Nanomedicine in Cancer Pathology

artículo científico publicado en 2018

New insight into structure-activity of furan-based salicylate synthase (MbtI) inhibitors as potential antitubercular agents

scientific article published on 01 December 2019

Optimization of a Benzoylpiperidine Class Identifies a Highly Potent and Selective Reversible Monoacylglycerol Lipase (MAGL) Inhibitor

artículo científico publicado en 2019

Pathological Role of Peptidyl-Prolyl Isomerase Pin1 in the Disruption of Synaptic Plasticity in Alzheimer's Disease.

artículo científico publicado en 2017

Pharmaco-metabolomics: an emerging "omics" tool for the personalization of anticancer treatments and identification of new valuable therapeutic targets

artículo científico publicado en 2012

Pharmacometabolomics study identifies circulating spermidine and tryptophan as potential biomarkers associated with the complete pathological response to trastuzumab-paclitaxel neoadjuvant therapy in HER-2 positive breast cancer.

scientific article published on 19 May 2016

Pin1 and nuclear receptors: a new language?

artículo científico publicado en 2013

Polymer-Mediated Delivery of siRNAs to Hepatocellular Carcinoma: Variables Affecting Specificity and Effectiveness

scientific article published on 28 March 2018

Proof-of-Concept Multistage Biomimetic Liposomal DNA Origami Nanosystem for the Remote Loading of Doxorubicin

scientific article published on 31 January 2019

R-Roscovitine (Seliciclib) prevents DNA damage-induced cyclin A1 upregulation and hinders non-homologous end-joining (NHEJ) DNA repair

artículo científico publicado en 2010

RB gene family: genome-wide ChIP approaches could open undiscovered roads.

artículo científico publicado en 2010

Rational Development of MAGL Inhibitors

artículo científico publicado en 2018

Rational design, synthesis and anti-proliferative properties of new CB2 selective cannabinoid receptor ligands: an investigation of the 1,8-naphthyridin-2(1H)-one scaffold.

artículo científico publicado en 2012

Redox modulation of vitagenes via plant polyphenols and vitamin D: Novel insights for chemoprevention and therapeutic interventions based on organoid technology

artículo científico publicado en 2021

Retinoblastoma tumor-suppressor protein phosphorylation and inactivation depend on direct interaction with Pin1.

artículo científico publicado en 2012

Self-Therapeutic Cobalt Hydroxide Nanosheets (Co(OH)<sub>2</sub> NS) for Ovarian Cancer Therapy

artículo científico publicado en 2021

Strategies for Delivery of siRNAs to Ovarian Cancer Cells

scientific article published on 22 October 2019

Strategies to optimize siRNA delivery to hepatocellular carcinoma cells.

artículo científico publicado en 2017

Structural Optimization of 4-Chlorobenzoylpiperidine Derivatives for the Development of Potent, Reversible, and Selective Monoacylglycerol Lipase (MAGL) Inhibitors.

artículo científico publicado en 2016

Synthesis and in-depth studies on the anticancer activity of novel palladacyclopentadienyl complexes stabilized by N-Heterocyclic carbene ligands

scientific article published on 22 June 2019

Targeting intracellular B2 receptors using novel cell-penetrating antagonists to arrest growth and induce apoptosis in human triple-negative breast cancer.

artículo científico publicado en 2018

The Clinical translation of Organic Nanomaterials for Cancer Therapy: A Focus on Polymeric Nanoparticles, Micelles, Liposomes and Exosomes.

artículo científico publicado en 2017

The History of Nanoscience and Nanotechnology: From Chemical-Physical Applications to Nanomedicine

artículo científico publicado en 2019

The ablation of EZH2 uncovers its crucial role in rhabdomyosarcoma formation.

artículo científico publicado en 2012

The prolyl isomerase Pin1 acts synergistically with CDK2 to regulate the basal activity of estrogen receptor α in breast cancer

artículo científico publicado en 2013

Virtual screening identifies a PIN1 inhibitor with possible antiovarian cancer effects

scientific article published on 29 January 2019

X chromosome and ovarian failure.

artículo científico publicado en 2007

pRb controls estrogen receptor alpha protein stability and activity.

artículo científico publicado en 2013

Lista de obras de Flavio Rizzolio

4-Aryliden-2-methyloxazol-5(4H)-one as a new scaffold for selective reversible MAGL inhibitors

A Guide to PIN1 Function and Mutations Across Cancers

A functional biological network centered on XRCC3: a new possible marker of chemoradiotherapy resistance in rectal cancer patients

A patent review of Monoacylglycerol Lipase (MAGL) inhibitors (2013-2017).

A susceptibility gene for premature ovarian failure (POF) maps to proximal Xq28

Alterations of the Plasma Peptidome Profiling in Colorectal Cancer Progression.

An Effective Multi-Stage Liposomal DNA Origami Nanosystem for In Vivo Cancer Therapy

An integrative approach for the identification of prognostic and predictive biomarkers in rectal cancer

An updated patent review of monoacylglycerol lipase (MAGL) inhibitors (2018-present)

Androgen receptor serine 81 mediates Pin1 interaction and activity

Application of MM-PBSA Methods in Virtual Screening

Binding investigation and preliminary optimisation of the 3-amino-1,2,4-triazin-5(2H)-one core for the development of new Fyn inhibitors.

Bottom-up synthesis of carbon nanoparticles with higher doxorubicin efficacy.

CDK inhibitors: from the bench to clinical trials.

Cancer Extracellular Vesicles: Next-Generation Diagnostic and Drug Delivery Nanotools

Carbon Dots from Sugars and Ascorbic Acid: Role of the Precursors on Morphology, Properties, Toxicity, and Drug Uptake

Characterization of the Saffron Derivative Crocetin as an Inhibitor of Human Lactate Dehydrogenase 5 in the Antiglycolytic Approach against Cancer.

Chromosomal rearrangements in Xq and premature ovarian failure: mapping of 25 new cases and review of the literature.

Clinical predictive circulating peptides in rectal cancer patients treated with neoadjuvant chemoradiotherapy

Combined effects of PI3K and SRC kinase inhibitors with imatinib on intracellular calcium levels, autophagy, and apoptosis in CML-PBL cells.

Computationally driven discovery of phenyl(piperazin-1-yl)methanone derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors

Corrigendum to “Fluorescent molecularly imprinted nanogels for the detection of anticancer drugs in human plasma” [Biosens. Bioelectron. 86 (2016) 913–919]

Critical choices for modeling breast cancer in transgenic mouse models.

Cyclic Ketoximes as Estrogen Receptor β Selective Agonists.

DNA Nanotechnology for Cancer Therapy

Decellularized colorectal cancer matrix as bioactive microenvironment for in vitro 3D cancer research

Development of terphenyl-2-methyloxazol-5(4H)-one derivatives as selective reversible MAGL inhibitors.

Discovery of 1,5-Diphenylpyrazole-3-Carboxamide Derivatives as Potent, Reversible, and Selective Monoacylglycerol Lipase (MAGL) Inhibitors.

Discovery of a new ATP-citrate lyase (ACLY) inhibitor identified by a pharmacophore-based virtual screening study

Discovery of long-chain salicylketoxime derivatives as monoacylglycerol lipase (MAGL) inhibitors

Dissecting Pin1 and phospho-pRb regulation.

Editorial: Peptidyl-Prolyl Isomerases in Human Pathologies

Emerging molecular networks in Burkitt's lymphoma.

Enhanced Chemotherapeutic Behavior of Open-Caged DNA@Doxorubicin Nanostructures for Cancer Cells

Epigenetic control of the critical region for premature ovarian failure on autosomal genes translocated to the X chromosome: a hypothesis.

Exosomal doxorubicin reduces the cardiac toxicity of doxorubicin

Exosomes increase the therapeutic index of doxorubicin in breast and ovarian cancer mouse models.

Extracellular Matrix and Colorectal Cancer: How Surrounding Microenvironment Affects Cancer Cell Behavior?

First-of-its-kind STARD3 Inhibitor: In Silico Identification and Biological Evaluation as Anticancer Agent

Fluorescent Carbon Nanoparticles in Medicine for Cancer Therapy: An Update.

Fluorescent carbon nanoparticles in medicine for cancer therapy

Fluorescent molecularly imprinted nanogels for the detection of anticancer drugs in human plasma

Gene and MicroRNA Expression Are Predictive of Tumor Response in Rectal Adenocarcinoma Patients Treated With Preoperative Chemoradiotherapy.

Highly conserved non-coding sequences and the 18q critical region for short stature: a common mechanism of disease?

Highly selective salicylketoxime-based estrogen receptor β agonists display antiproliferative activities in a glioma model

Hyaluronan esters drive Smad gene expression and signaling enhancing cardiogenesis in mouse embryonic and human mesenchymal stem cells

Identification and characterization of a new reversible MAGL inhibitor

Identification of new Fyn kinase inhibitors using a FLAP-based approach.

Impact of DNA repair gene polymorphisms on the risk of biochemical recurrence after radiotherapy and overall survival in prostate cancer

Inorganic Nanoparticles for Cancer Therapy: A Transition from Lab to Clinic

Liposomal delivery of a Pin1 inhibitor complexed with cyclodextrins as new therapy for high-grade serous ovarian cancer

MTHFR-1298 A>C (rs1801131) is a predictor of survival in two cohorts of stage II/III colorectal cancer patients treated with adjuvant fluoropyrimidine chemotherapy with or without oxaliplatin

Metabolomics biomarkers of frailty in elderly breast cancer patients.

Nanomedicine in Cancer Pathology

New insight into structure-activity of furan-based salicylate synthase (MbtI) inhibitors as potential antitubercular agents

Optimization of a Benzoylpiperidine Class Identifies a Highly Potent and Selective Reversible Monoacylglycerol Lipase (MAGL) Inhibitor

Pathological Role of Peptidyl-Prolyl Isomerase Pin1 in the Disruption of Synaptic Plasticity in Alzheimer's Disease.

Pharmaco-metabolomics: an emerging "omics" tool for the personalization of anticancer treatments and identification of new valuable therapeutic targets

Pharmacometabolomics study identifies circulating spermidine and tryptophan as potential biomarkers associated with the complete pathological response to trastuzumab-paclitaxel neoadjuvant therapy in HER-2 positive breast cancer.

Pin1 and nuclear receptors: a new language?

Polymer-Mediated Delivery of siRNAs to Hepatocellular Carcinoma: Variables Affecting Specificity and Effectiveness

Proof-of-Concept Multistage Biomimetic Liposomal DNA Origami Nanosystem for the Remote Loading of Doxorubicin

R-Roscovitine (Seliciclib) prevents DNA damage-induced cyclin A1 upregulation and hinders non-homologous end-joining (NHEJ) DNA repair

RB gene family: genome-wide ChIP approaches could open undiscovered roads.

Rational Development of MAGL Inhibitors

Rational design, synthesis and anti-proliferative properties of new CB2 selective cannabinoid receptor ligands: an investigation of the 1,8-naphthyridin-2(1H)-one scaffold.

Redox modulation of vitagenes via plant polyphenols and vitamin D: Novel insights for chemoprevention and therapeutic interventions based on organoid technology

Retinoblastoma tumor-suppressor protein phosphorylation and inactivation depend on direct interaction with Pin1.

Self-Therapeutic Cobalt Hydroxide Nanosheets (Co(OH)<sub>2</sub> NS) for Ovarian Cancer Therapy

Strategies for Delivery of siRNAs to Ovarian Cancer Cells

Strategies to optimize siRNA delivery to hepatocellular carcinoma cells.

Structural Optimization of 4-Chlorobenzoylpiperidine Derivatives for the Development of Potent, Reversible, and Selective Monoacylglycerol Lipase (MAGL) Inhibitors.

Synthesis and in-depth studies on the anticancer activity of novel palladacyclopentadienyl complexes stabilized by N-Heterocyclic carbene ligands

Targeting intracellular B2 receptors using novel cell-penetrating antagonists to arrest growth and induce apoptosis in human triple-negative breast cancer.

The Clinical translation of Organic Nanomaterials for Cancer Therapy: A Focus on Polymeric Nanoparticles, Micelles, Liposomes and Exosomes.

The History of Nanoscience and Nanotechnology: From Chemical-Physical Applications to Nanomedicine

The ablation of EZH2 uncovers its crucial role in rhabdomyosarcoma formation.

The prolyl isomerase Pin1 acts synergistically with CDK2 to regulate the basal activity of estrogen receptor α in breast cancer

Virtual screening identifies a PIN1 inhibitor with possible antiovarian cancer effects