Lista de obras - William D Martin - Dominio Público Uruguay

A comparison of two methods for T cell epitope mapping: "cell free" in vitro versus immunoinformatics.

artículo científico publicado en 2011

A dominant EV71-specific CD4+ T cell epitope is highly conserved among human enteroviruses

artículo científico publicado en 2012

A humanized mouse model identifies key amino acids for low immunogenicity of H7N9 vaccines.

artículo científico publicado en 2017

A method for individualizing the prediction of immunogenicity of protein vaccines and biologic therapeutics: individualized T cell epitope measure (iTEM).

artículo científico publicado en 2010

Activation of natural regulatory T cells by IgG Fc-derived peptide "Tregitopes"

artículo científico publicado en 2008

Agility in adversity: Vaccines on Demand

artículo científico publicado en 2016

An Integrated Genomic and Immunoinformatic Approach to H. pylori Vaccine Design.

artículo científico publicado en 2011

An immunoinformatic approach for identification of Trypanosoma cruzi HLA-A2-restricted CD8(+) T cell epitopes.

artículo científico publicado en 2015

An immunoinformatics-derived DNA vaccine encoding human class II T cell epitopes of Ebola virus, Sudan virus, and Venezuelan equine encephalitis virus is immunogenic in HLA transgenic mice

artículo científico publicado en 2017

Analysis of ChimeriVax Japanese Encephalitis Virus envelope for T-cell epitopes and comparison to circulating strain sequences

artículo científico publicado en 2007

Application of IgG-derived natural Treg epitopes (IgG Tregitopes) to antigen-specific tolerance induction in a murine model of type 1 diabetes

artículo científico publicado en 2013

Aspartate-β-hydroxylase induces epitope-specific T cell responses in hepatocellular carcinoma

artículo científico publicado en 2015

Beyond humanization and de-immunization: tolerization as a method for reducing the immunogenicity of biologics

artículo científico publicado en 2013

Bioinformatics tools for identifying class I-restricted epitopes

artículo científico publicado en 2003

C3d adjuvant effects are mediated through the activation of C3d-specific autoreactive T cells

artículo científico publicado en 2014

CHOPPI: a web tool for the analysis of immunogenicity risk from host cell proteins in CHO-based protein production.

artículo científico publicado en 2014

Conservation of HIV-1 T cell epitopes across time and clades: validation of immunogenic HLA-A2 epitopes selected for the GAIA HIV vaccine

artículo científico publicado en 2012

Correction: A Dominant EV71-Specific CD4+ T Cell Epitope Is Highly Conserved among Human Enteroviruses.

artículo científico publicado en 2014

Coupling sensitive in vitro and in silico techniques to assess cross-reactive CD4(+) T cells against the swine-origin H1N1 influenza virus

artículo científico publicado en 2011

Cross-conservation of T-cell epitopes: now even more relevant to (H7N9) influenza vaccine design.

artículo científico publicado en 2014

De-immunized and Functional Therapeutic (DeFT) versions of a long lasting recombinant alpha interferon for antiviral therapy

artículo científico publicado en 2017

Dendritic cell-mediated, DNA-based vaccination against hepatitis C induces the multi-epitope-specific response of humanized, HLA transgenic mice

artículo científico publicado en 2014

Development and validation of an epitope prediction tool for swine (PigMatrix) based on the pocket profile method

artículo científico publicado en 2015

Effect of HLA DR epitope de-immunization of Factor VIII in vitro and in vivo.

artículo científico publicado en 2011

Engineering immunogenic consensus T helper epitopes for a cross-clade HIV vaccine

artículo científico publicado en 2004

Epitope recognition in HLA-DR3 transgenic mice immunized to TSH-R protein or peptides

artículo científico publicado en 2013

Epitope-based vaccination against pneumonic tularemia

artículo científico publicado en 2009

Epitope-driven TB vaccine development: a streamlined approach using immuno-informatics, ELISpot assays, and HLA transgenic mice

artículo científico publicado en 2007

Evolutionary deimmunization: An ancillary mechanism for self-tolerance?

article

Further progress on defining highly conserved immunogenic epitopes for a global HIV vaccine: HLA-A3-restricted GAIA vaccine epitopes

article

H7N9 T-cell epitopes that mimic human sequences are less immunogenic and may induce Treg-mediated tolerance.

artículo científico publicado en 2015

HCV epitope, homologous to multiple human protein sequences, induces a regulatory T cell response in infected patients

artículo científico publicado en 2014

HIV vaccine development by computer assisted design: the GAIA vaccine

artículo científico publicado en 2005

HelicoVax: epitope-based therapeutic Helicobacter pylori vaccination in a mouse model

artículo científico publicado en 2011

Human immune responses to H. pylori HLA Class II epitopes identified by immunoinformatic methods.

artículo científico publicado en 2014

Identification of genome-derived vaccine candidates conserved between human and mouse-adapted strains of H. pylori

artículo científico publicado en 2008

Identification of immunogenic HLA-B7 "Achilles' heel" epitopes within highly conserved regions of HIV

artículo científico publicado en 2007

Immune camouflage: relevance to vaccines and human immunology

artículo científico publicado en 2014

Immune escape and immune camouflage may reduce the efficacy of RTS,S vaccine in Malawi

artículo científico publicado en 2019

Immunization with cross-conserved H1N1 influenza CD4+ T-cell epitopes lowers viral burden in HLA DR3 transgenic mice

artículo científico publicado en 2013

Immuno-informatics: Mining genomes for vaccine components

artículo científico publicado en 2002

Immunogenic Consensus Sequence T helper Epitopes for a Pan-Burkholderia Biodefense Vaccine.

artículo científico publicado en 2011

Immunogenicity Screening Usingin Silico Methods: Correlation between T-Cell Epitope Content and Clinical Immunogenicity of Monoclonal Antibodies

article

Immunoinformatic analysis of Chinese hamster ovary (CHO) protein contaminants in therapeutic protein formulations

article

Immunoinformatic approach to a multi-pathogen genome-derived epitope-driven vaccine

Immunoinformatic comparison of T-cell epitopes contained in novel swine-origin influenza A (H1N1) virus with epitopes in 2008-2009 conventional influenza vaccine

artículo científico publicado en 2009

Immunoinformatic discovery of potential cross-reactive T cell epitopes in the measles genome

article

Immunoinformatic-drivenH. pylorivaccine design

article

Immunoinformatics Applied to Modifying and Improving Biological Therapeutics

article

Immunoinformatics: The Next Step in Vaccine Design

article

In Vivo Validation of Predicted and Conserved T Cell Epitopes in a Swine Influenza Model.

artículo científico publicado en 2016

In silico-accelerated identification of conserved and immunogenic variola/vaccinia T-cell epitopes.

artículo científico publicado en 2009

Integrated assessment of predicted MHC binding and cross-conservation with self reveals patterns of viral camouflage

artículo científico publicado en 2014

Low immunogenicity predicted for emerging avian-origin H7N9: implication for influenza vaccine design.

artículo científico publicado en 2013

Making vaccines "on demand": a potential solution for emerging pathogens and biodefense?

artículo científico publicado en 2013

Mapping cross-clade HIV-1 vaccine epitopes using a bioinformatics approach

artículo científico publicado en 2003

Novel function of complement C3d as an autologous helper T-cell target

artículo científico publicado en 2008

Partial pathogen protection by tick-bite sensitization and epitope recognition in peptide-immunized HLA DR3 transgenic mice.

artículo científico publicado en 2014

Peptide-pulsed dendritic cells induce the hepatitis C viral epitope-specific responses of naïve human T cells

artículo científico publicado en 2014

Reducing risk, improving outcomes: bioengineering less immunogenic protein therapeutics

artículo científico publicado en 2009

Smarter vaccine design will circumvent regulatory T cell-mediated evasion in chronic HIV and HCV infection

artículo científico publicado en 2014

T cell epitope engineering: an avian H7N9 influenza vaccine strategy for pandemic preparedness and response

scholarly article by Leonard Moise et al published 17 July 2018 in Human Vaccines & Immunotherapeutics

T cell epitope identification for bovine vaccines: an epitope mapping method for BoLA A-11.

artículo científico publicado en 2003

T cell epitope redundancy: cross-conservation of the TCR face between pathogens and self and its implications for vaccines and autoimmunity

artículo científico publicado en 2015

T-cell epitope content comparison (EpiCC) of swine H1 influenza A virus hemagglutinin

artículo científico publicado en 2017

Teaching tolerance: New approaches to enzyme replacement therapy for Pompe disease

artículo científico publicado en 2012

The role of glutamic or aspartic acid in position four of the epitope binding motif and thyrotropin receptor-extracellular domain epitope selection in Graves' disease

artículo científico publicado en 2010

The two-faced T cell epitope: examining the host-microbe interface with JanusMatrix.

scientific article published on 12 April 2013

Therapeutic administration of Tregitope-Human Albumin Fusion with Insulin Peptides to promote Antigen-Specific Adaptive Tolerance Induction

artículo científico publicado en 2019

Thyrotropin receptor epitopes and their relation to histocompatibility leukocyte antigen-DR molecules in Graves' disease

artículo científico publicado en 2006

Time for T?: Thoughts about the 2009 novel H1N1 influenza outbreak and the role of T cell epitopes in the next generation of influenza vaccines

artículo científico publicado en 2010

Tools for Vaccine Design: Prediction and Validation of Highly Immunogenic and Conserved Class II Epitopes and Development of Epitope-Driven Vaccines

article

Tregitope peptides: the active pharmaceutical ingredient of IVIG?

scientific article published on 25 December 2013

Tregitope: Immunomodulation powerhouse

artículo científico publicado en 2014

Universal H1N1 influenza vaccine development: identification of consensus class II hemagglutinin and neuraminidase epitopes derived from strains circulating between 1980 and 2011.

artículo científico publicado en 2013

Vaccination and Autoimmunity

scholarly article published 28 January 2004

VaxCelerate II: rapid development of a self-assembling vaccine for Lassa fever

artículo científico publicado en 2014

VennVax, a DNA-prime, peptide-boost multi-T-cell epitope poxvirus vaccine, induces protective immunity against vaccinia infection by T cell response alone

artículo científico publicado en 2010

Lista de obras de William D Martin

A comparison of two methods for T cell epitope mapping: "cell free" in vitro versus immunoinformatics.

A dominant EV71-specific CD4+ T cell epitope is highly conserved among human enteroviruses

A humanized mouse model identifies key amino acids for low immunogenicity of H7N9 vaccines.

A method for individualizing the prediction of immunogenicity of protein vaccines and biologic therapeutics: individualized T cell epitope measure (iTEM).

Activation of natural regulatory T cells by IgG Fc-derived peptide "Tregitopes"

Agility in adversity: Vaccines on Demand

An Integrated Genomic and Immunoinformatic Approach to H. pylori Vaccine Design.

An immunoinformatic approach for identification of Trypanosoma cruzi HLA-A2-restricted CD8(+) T cell epitopes.

An immunoinformatics-derived DNA vaccine encoding human class II T cell epitopes of Ebola virus, Sudan virus, and Venezuelan equine encephalitis virus is immunogenic in HLA transgenic mice

Analysis of ChimeriVax Japanese Encephalitis Virus envelope for T-cell epitopes and comparison to circulating strain sequences

Application of IgG-derived natural Treg epitopes (IgG Tregitopes) to antigen-specific tolerance induction in a murine model of type 1 diabetes

Aspartate-β-hydroxylase induces epitope-specific T cell responses in hepatocellular carcinoma

Beyond humanization and de-immunization: tolerization as a method for reducing the immunogenicity of biologics

Bioinformatics tools for identifying class I-restricted epitopes

C3d adjuvant effects are mediated through the activation of C3d-specific autoreactive T cells

CHOPPI: a web tool for the analysis of immunogenicity risk from host cell proteins in CHO-based protein production.

Conservation of HIV-1 T cell epitopes across time and clades: validation of immunogenic HLA-A2 epitopes selected for the GAIA HIV vaccine

Correction: A Dominant EV71-Specific CD4+ T Cell Epitope Is Highly Conserved among Human Enteroviruses.

Coupling sensitive in vitro and in silico techniques to assess cross-reactive CD4(+) T cells against the swine-origin H1N1 influenza virus

Cross-conservation of T-cell epitopes: now even more relevant to (H7N9) influenza vaccine design.

De-immunized and Functional Therapeutic (DeFT) versions of a long lasting recombinant alpha interferon for antiviral therapy

Dendritic cell-mediated, DNA-based vaccination against hepatitis C induces the multi-epitope-specific response of humanized, HLA transgenic mice

Development and validation of an epitope prediction tool for swine (PigMatrix) based on the pocket profile method

Effect of HLA DR epitope de-immunization of Factor VIII in vitro and in vivo.

Engineering immunogenic consensus T helper epitopes for a cross-clade HIV vaccine

Epitope recognition in HLA-DR3 transgenic mice immunized to TSH-R protein or peptides

Epitope-based vaccination against pneumonic tularemia

Epitope-driven TB vaccine development: a streamlined approach using immuno-informatics, ELISpot assays, and HLA transgenic mice

Evolutionary deimmunization: An ancillary mechanism for self-tolerance?

Further progress on defining highly conserved immunogenic epitopes for a global HIV vaccine: HLA-A3-restricted GAIA vaccine epitopes

H7N9 T-cell epitopes that mimic human sequences are less immunogenic and may induce Treg-mediated tolerance.

HCV epitope, homologous to multiple human protein sequences, induces a regulatory T cell response in infected patients

HIV vaccine development by computer assisted design: the GAIA vaccine

HelicoVax: epitope-based therapeutic Helicobacter pylori vaccination in a mouse model

Human immune responses to H. pylori HLA Class II epitopes identified by immunoinformatic methods.

Identification of genome-derived vaccine candidates conserved between human and mouse-adapted strains of H. pylori

Identification of immunogenic HLA-B7 "Achilles' heel" epitopes within highly conserved regions of HIV

Immune camouflage: relevance to vaccines and human immunology

Immune escape and immune camouflage may reduce the efficacy of RTS,S vaccine in Malawi

Immunization with cross-conserved H1N1 influenza CD4+ T-cell epitopes lowers viral burden in HLA DR3 transgenic mice

Immuno-informatics: Mining genomes for vaccine components

Immunogenic Consensus Sequence T helper Epitopes for a Pan-Burkholderia Biodefense Vaccine.

Immunogenicity Screening Usingin Silico Methods: Correlation between T-Cell Epitope Content and Clinical Immunogenicity of Monoclonal Antibodies

Immunoinformatic analysis of Chinese hamster ovary (CHO) protein contaminants in therapeutic protein formulations

Immunoinformatic approach to a multi-pathogen genome-derived epitope-driven vaccine

Immunoinformatic comparison of T-cell epitopes contained in novel swine-origin influenza A (H1N1) virus with epitopes in 2008-2009 conventional influenza vaccine

Immunoinformatic discovery of potential cross-reactive T cell epitopes in the measles genome

Immunoinformatic-drivenH. pylorivaccine design

Immunoinformatics Applied to Modifying and Improving Biological Therapeutics

Immunoinformatics: The Next Step in Vaccine Design

In Vivo Validation of Predicted and Conserved T Cell Epitopes in a Swine Influenza Model.

In silico-accelerated identification of conserved and immunogenic variola/vaccinia T-cell epitopes.

Integrated assessment of predicted MHC binding and cross-conservation with self reveals patterns of viral camouflage

Low immunogenicity predicted for emerging avian-origin H7N9: implication for influenza vaccine design.

Making vaccines "on demand": a potential solution for emerging pathogens and biodefense?

Mapping cross-clade HIV-1 vaccine epitopes using a bioinformatics approach

Novel function of complement C3d as an autologous helper T-cell target

Partial pathogen protection by tick-bite sensitization and epitope recognition in peptide-immunized HLA DR3 transgenic mice.

Peptide-pulsed dendritic cells induce the hepatitis C viral epitope-specific responses of naïve human T cells

Reducing risk, improving outcomes: bioengineering less immunogenic protein therapeutics

Smarter vaccine design will circumvent regulatory T cell-mediated evasion in chronic HIV and HCV infection

T cell epitope engineering: an avian H7N9 influenza vaccine strategy for pandemic preparedness and response

T cell epitope identification for bovine vaccines: an epitope mapping method for BoLA A-11.

T cell epitope redundancy: cross-conservation of the TCR face between pathogens and self and its implications for vaccines and autoimmunity

T-cell epitope content comparison (EpiCC) of swine H1 influenza A virus hemagglutinin

Teaching tolerance: New approaches to enzyme replacement therapy for Pompe disease

The role of glutamic or aspartic acid in position four of the epitope binding motif and thyrotropin receptor-extracellular domain epitope selection in Graves' disease

The two-faced T cell epitope: examining the host-microbe interface with JanusMatrix.

Therapeutic administration of Tregitope-Human Albumin Fusion with Insulin Peptides to promote Antigen-Specific Adaptive Tolerance Induction

Thyrotropin receptor epitopes and their relation to histocompatibility leukocyte antigen-DR molecules in Graves' disease

Time for T?: Thoughts about the 2009 novel H1N1 influenza outbreak and the role of T cell epitopes in the next generation of influenza vaccines

Tools for Vaccine Design: Prediction and Validation of Highly Immunogenic and Conserved Class II Epitopes and Development of Epitope-Driven Vaccines

Tregitope peptides: the active pharmaceutical ingredient of IVIG?

Tregitope: Immunomodulation powerhouse

Universal H1N1 influenza vaccine development: identification of consensus class II hemagglutinin and neuraminidase epitopes derived from strains circulating between 1980 and 2011.

Vaccination and Autoimmunity

VaxCelerate II: rapid development of a self-assembling vaccine for Lassa fever

VennVax, a DNA-prime, peptide-boost multi-T-cell epitope poxvirus vaccine, induces protective immunity against vaccinia infection by T cell response alone