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A critical role for Egr-1 during vascular remodelling in pulmonary arterial hypertension

artículo científico publicado en 2014

Advances in the delivery of RNA therapeutics: from concept to clinical reality.

artículo científico publicado en 2017

Anti-VCAM-1 SAINT-O-Somes enable endothelial-specific delivery of siRNA and downregulation of inflammatory genes in activated endothelium in vivo.

artículo científico publicado en 2014

Anti-VCAM-1 and anti-E-selectin SAINT-O-Somes for selective delivery of siRNA into inflammation-activated primary endothelial cells.

artículo científico publicado en 2013

Delivering the Messenger: Advances in Technologies for Therapeutic mRNA Delivery

scientific article published on 19 February 2019

Effective siRNA delivery to inflamed primary vascular endothelial cells by anti-E-selectin and anti-VCAM-1 PEGylated SAINT-based lipoplexes.

artículo científico publicado en 2013

Efficacy and immunogenicity of unmodified and pseudouridine-modified mRNA delivered systemically with lipid nanoparticles in vivo.

artículo científico publicado en 2016

Endothelial miR-30c suppresses tumor growth via inhibition of TGF-β-induced Serpine1

artículo científico publicado en 2019

Endothelial siRNA delivery in nonhuman primates using ionizable low-molecular weight polymeric nanoparticles.

artículo científico publicado en 2018

Endothelium-targeted delivery of dexamethasone by anti-VCAM-1 SAINT-O-Somes in mouse endotoxemia.

artículo científico publicado en 2018

Engineering circular RNA for potent and stable translation in eukaryotic cells.

artículo científico publicado en 2018

Heparin enhances serpin inhibition of the cysteine protease cathepsin L.

artículo científico publicado en 2009

Ionizable Amino-Polyesters Synthesized via Ring Opening Polymerization of Tertiary Amino-Alcohols for Tissue Selective mRNA Delivery

artículo científico publicado en 2018

Ly6Clo monocytes drive immunosuppression and confer resistance to anti-VEGFR2 cancer therapy.

artículo científico publicado en 2017

Nanoparticle-encapsulated siRNAs for gene silencing in the haematopoietic stem-cell niche

scientific article published on 05 October 2020

RNA Circularization Diminishes Immunogenicity and Can Extend Translation Duration In Vivo

artículo científico publicado en 2019

SAINT-liposome-polycation particles, a new carrier for improved delivery of siRNAs to inflamed endothelial cells

scientific article published on 25 November 2014

Smart Biomaterials: Recent Advances and Future Directions

artículo científico publicado en 2018

Targeted siRNA delivery to diseased microvascular endothelial cells: cellular and molecular concepts.

artículo científico publicado en 2011

VCAM-1 specific PEGylated SAINT-based lipoplexes deliver siRNA to activated endothelium in vivo but do not attenuate target gene expression.

artículo científico publicado en 2014

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