Lista de obras - Sandrine Sagan - Dominio Público Uruguay

A direct approach to quantification of the cellular uptake of cell-penetrating peptides using MALDI-TOF mass spectrometry

artículo científico publicado en 2006

A direct label-free MALDI-TOF mass spectrometry based assay for the characterization of inhibitors of protein lysine methyltransferases.

artículo científico publicado en 2017

A proapoptotic peptide conjugated to penetratin selectively inhibits tumor cell growth.

artículo científico publicado en 2014

Amphiphilic macromolecules on cell membranes: from protective layers to controlled permeabilization.

artículo científico publicado en 2014

An Artificial Amphiphilic Peptide Promotes Endocytic Uptake by Inducing Membrane Curvature

scientific article published on 07 May 2020

Analogs of Substance P modified at the C-terminus which are both agonist and antagonist of the NK-1 receptor depending on the second messenger pathway.

artículo científico publicado en 2002

Analysis of an intact G-protein coupled receptor by MALDI-TOF mass spectrometry: molecular heterogeneity of the tachykinin NK-1 receptor

artículo científico publicado en 2007

Anandamide and WIN 55212-2 inhibit cyclic AMP formation through G-protein-coupled receptors distinct from CB1 cannabinoid receptors in cultured astrocytes.

artículo científico publicado en 1999

Antimicrobial activity of lysozyme isoforms: Key molecular features.

artículo científico publicado en 2017

Asymmetric synthesis of Boc- N -methyl- p -benzoyl-phenylalanine. preparation of a photoreactive antagonist of Substance P

scientific article published on 01 June 1998

Benzophenone Photoreactivity in a Lipid Bilayer To Probe Peptide/Membrane Interactions: Simple System, Complex Information

artículo científico publicado en 2019

Biological activity of silylated amino acid containing substance P analogues.

artículo científico publicado en 2004

Cell-penetrating peptides: 20 years later, where do we stand?

artículo científico

Cellular uptake and biophysical properties of galactose and/or tryptophan containing cell-penetrating peptides.

artículo científico publicado en 2011

Characterisation and visualisation of [3H]dermorphin binding to mu opioid receptors in the rat brain. Combined high selectivity and affinity in a natural peptide agonist for the morphine (mu) receptor.

artículo científico publicado en 1990

Characterization of the bioactive conformation of the C-terminal tripeptide Gly-Leu-Met-NH2 of substance P using [3-prolinoleucine10]SP analogues

artículo científico publicado en 2003

Comparing lipid photo-cross-linking efficacy of penetratin analogues bearing three different photoprobes: dithienyl ketone, benzophenone, and trifluoromethylaryldiazirine.

artículo científico publicado en 2010

Conformational analysis of the C-terminal Gly-Leu-Met-NH2 tripeptide of substance P bound to the NK-1 receptor

artículo científico publicado en 2005

Correction to Sequence-Dependent Enrichment of a Model Phosphopeptide: A Combined MALDI-TOF and NMR Study

artículo científico publicado en 2011

Dermorphin and related peptides in rat tissues

artículo científico publicado en 1989

Different membrane behaviour and cellular uptake of three basic arginine-rich peptides

artículo científico publicado en 2010

Differential contribution of C-terminal regions of dermorphin and dermenkephalin to opioid-sites selection and binding potency.

artículo científico publicado en 1989

Direct translocation of cell-penetrating peptides in liposomes: A combined mass spectrometry quantification and fluorescence detection study ⬇️

artículo científico publicado el 20 de marzo de 2013

ECL1i, d(LGTFLKC), a novel, small peptide that specifically inhibits CCL2-dependent migration.

artículo científico publicado en 2016

ERα17p, a peptide reproducing the hinge region of the estrogen receptor α associates to biological membranes: A biophysical approach

artículo científico publicado en 2012

Exploiting Benzophenone Photoreactivity To Probe the Phospholipid Environment and Insertion Depth of the Cell-Penetrating Peptide Penetratin in Model Membranes

artículo científico publicado en 2017

Further Delineation of the Two Binding Sites (R*n) Associated with Tachykinin Neurokinin-1 Receptors Using [3-Prolinomethionine11]SP Analogues

artículo científico publicado en 1999

Glycosylated cell-penetrating peptides and their conjugates to a proapoptotic peptide: preparation by click chemistry and cell viability studies.

artículo científico publicado en 2009

Graftable SCoMPIs enable the labeling and X-ray fluorescence imaging of proteins.

artículo científico publicado en 2018

Head to tail cyclisation of cell-penetrating peptides: impact on GAG-dependent internalisation and direct translocation

artículo científico publicado en 2019

High Affinity Binding of [3H]Propionyl-[Met(O2)11]Substance P(7–11), a Tritiated Septide-Like Peptide, in Chinese Hamster Ovary Cells Expressing Human Neurokinin-1 Receptors and in Rat Submandibular Glands ⬇️

artículo científico publicado el 1 de julio de 1997

Homeoproteins and homeoprotein-derived peptides: going in and out.

artículo científico

Incorporation of vinylogous scaffolds in the C-terminal tripeptide of substance P.

artículo científico publicado en 2004

Interaction of the Anti-Proliferative GPER Inverse Agonist ERα17p with the Breast Cancer Cell Plasma Membrane: From Biophysics to Biology

artículo científico publicado en 2020

Internalization of [3H]substance P analogues in NK-1 receptor transfected CHO cells.

artículo científico publicado en 2001

Involvement of the second extracellular loop (E2) of the neurokinin-1 receptor in the binding of substance P. Photoaffinity labeling and modeling studies

artículo científico publicado en 2002

Ionpair-π interactions favor cell penetration of arginine/tryptophan-rich cell-penetrating peptides

scientific article published on 30 October 2019

Is there anybody in there? On the mechanisms of wall crossing of cell penetrating peptides.

artículo científico publicado en 2012

Isolation of dermenkephalin from amphibian skin, a high-affinity delta-selective opioid heptapeptide containing a D-amino acid residue.

artículo científico publicado en 1989

Isotope and affinity tags in photoreactive substance P analogues to identify the covalent linkage within the NK-1 receptor by MALDI-TOF analysis.

artículo científico publicado en 2003

Label-free measurement of histone lysine methyltransferases activity by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

artículo científico publicado en 2014

Lipid reorganization induced by membrane-active peptides probed using differential scanning calorimetry.

artículo científico publicado en 2009

MALDI-TOF mass spectrometry analysis of amphipol-trapped membrane proteins.

artículo científico publicado en 2012

MALDI-TOF mass spectrometry: a powerful tool to study the internalization of cell-penetrating peptides

artículo científico publicado en 2009

Massive glycosaminoglycan-dependent entry of Trp-containing cell-penetrating peptides induced by exogenous sphingomyelinase or cholesterol depletion

artículo científico publicado en 2014

Membrane Crossing and Membranotropic Activity of Cell-Penetrating Peptides: Dangerous Liaisons?

artículo científico publicado en 2017

Membrane interaction and perturbation mechanisms induced by two cationic cell penetrating peptides with distinct charge distribution.

artículo científico publicado en 2008

Membrane interactions of two arginine-rich peptides with different cell internalization capacities

artículo científico publicado en 2012

Met174 side chain is the site of photoinsertion of a substance P competitive peptide antagonist photoreactive in position 8.

artículo científico publicado en 2003

Molecular partners for interaction and cell internalization of cell-penetrating peptides: how identical are they?

N- and Calpha-methylation in biologically active peptides: synthesis, structural and functional aspects.

artículo científico publicado en 2004

Opioid activity of dermenkephalin analogues in the guinea-pig myenteric plexus and the hamster vas deferens.

artículo científico publicado en 1991

Pachymodulin, a new functional formyl peptide receptor 2 peptidic ligand isolated from frog skin has Janus-like immunomodulatory capacities.

artículo científico publicado en 2015

Peptide-grafted nanodiamonds: preparation, cytotoxicity and uptake in cells.

artículo científico publicado en 2008

Peptidoglycan potentiates the membrane disrupting effect of the carboxyamidated form of DMS-DA6, a Gram-positive selective antimicrobial peptide isolated from Pachymedusa dacnicolor skin

scientific article published in PLoS ONE

Photocontrol of the translocation of molecules, peptides, and quantum dots through cell and lipid membranes doped with azobenzene copolymers.

artículo científico publicado en 2012

Probing the in-air growth of large area of 3D functional structures into a 2D supramolecular nanoporous network

scholarly article by Romain Brisse et al published 6 September 2018 in Chemical Communications

Proteomic comparison of the EWS-FLI1 expressing cells EF with NIH-3T3 and actin remodeling effect of (R/W)9 cell-penetrating peptide.

artículo científico publicado en 2015

Quantification of the cellular uptake of cell-penetrating peptides by MALDI-TOF mass spectrometry

artículo científico publicado en 2005

Quantification of the efficiency of cargo delivery by peptidic and pseudo-peptidic Trojan carriers using MALDI-TOF mass spectrometry

artículo científico publicado en 2006

Quantitative fluorescence spectroscopy and flow cytometry analyses of cell-penetrating peptides internalization pathways: optimization, pitfalls, comparison with mass spectrometry quantification

artículo científico publicado en 2016

Relationships between membrane binding, affinity and cell internalization efficacy of a cell-penetrating peptide: penetratin as a case study.

artículo científico publicado en 2011

Self-assembling mini cell-penetrating peptides enter by both direct translocation and glycosaminoglycan-dependent endocytosis.

artículo científico publicado en 2012

Sequence-dependent enrichment of a model phosphopeptide: a combined MALDI-TOF and NMR study

artículo científico publicado en 2011

Small AntiMicrobial Peptide With in Vivo Activity Against Sepsis.

artículo científico publicado en 2019

Structural and biological effects of a β2- or β3-amino acid insertion in a peptide

artículo científico publicado en 2003

Structure and Dynamics of an Intrinsically Disordered Protein Region That Partially Folds upon Binding by Chemical-Exchange NMR.

artículo científico publicado en 2017

Study of CPP Mechanisms by Mass Spectrometry

artículo científico publicado en 2015

Tachykinin NK-1 receptor probed with constrained analogues of substance P.

artículo científico publicado en 1996

The aspartic acid in deltorphin I and dermenkephalin promotes targeting to delta-opioid receptor independently of receptor binding

artículo científico publicado el 30 de septiembre de 1992

The human sperm protein PH-20 has hyaluronidase activity.

artículo científico publicado en 1993

The interaction of cell-penetrating peptides with lipid model systems and subsequent lipid reorganization: thermodynamic and structural characterization.

artículo científico publicado en 2009

The role of tryptophans on the cellular uptake and membrane interaction of arginine-rich cell penetrating peptides.

artículo científico publicado en 2014

The two NK-1 binding sites correspond to distinct, independent, and non-interconvertible receptor conformational states as confirmed by plasmon-waveguide resonance spectroscopy.

artículo científico publicado en 2006

Tracking a new cell-penetrating (W/R) nonapeptide, through an enzyme-stable mass spectrometry reporter tag.

artículo científico publicado en 2007

Translocation and endocytosis for cell-penetrating peptide internalization

artículo científico publicado en 2009

Tryptophan within basic peptide sequences triggers glycosaminoglycan-dependent endocytosis.

artículo científico publicado en 2012

V(H)H (nanobody) directed against human glycophorin A: a tool for autologous red cell agglutination assays

artículo científico publicado en 2013

Lista de obras de Sandrine Sagan

A direct approach to quantification of the cellular uptake of cell-penetrating peptides using MALDI-TOF mass spectrometry

A direct label-free MALDI-TOF mass spectrometry based assay for the characterization of inhibitors of protein lysine methyltransferases.

A proapoptotic peptide conjugated to penetratin selectively inhibits tumor cell growth.

Amphiphilic macromolecules on cell membranes: from protective layers to controlled permeabilization.

An Artificial Amphiphilic Peptide Promotes Endocytic Uptake by Inducing Membrane Curvature

Analogs of Substance P modified at the C-terminus which are both agonist and antagonist of the NK-1 receptor depending on the second messenger pathway.

Analysis of an intact G-protein coupled receptor by MALDI-TOF mass spectrometry: molecular heterogeneity of the tachykinin NK-1 receptor

Anandamide and WIN 55212-2 inhibit cyclic AMP formation through G-protein-coupled receptors distinct from CB1 cannabinoid receptors in cultured astrocytes.

Antimicrobial activity of lysozyme isoforms: Key molecular features.

Asymmetric synthesis of Boc- N -methyl- p -benzoyl-phenylalanine. preparation of a photoreactive antagonist of Substance P

Benzophenone Photoreactivity in a Lipid Bilayer To Probe Peptide/Membrane Interactions: Simple System, Complex Information

Biological activity of silylated amino acid containing substance P analogues.

Cell-penetrating peptides: 20 years later, where do we stand?

Cellular uptake and biophysical properties of galactose and/or tryptophan containing cell-penetrating peptides.

Characterisation and visualisation of [3H]dermorphin binding to mu opioid receptors in the rat brain. Combined high selectivity and affinity in a natural peptide agonist for the morphine (mu) receptor.

Characterization of the bioactive conformation of the C-terminal tripeptide Gly-Leu-Met-NH2 of substance P using [3-prolinoleucine10]SP analogues

Comparing lipid photo-cross-linking efficacy of penetratin analogues bearing three different photoprobes: dithienyl ketone, benzophenone, and trifluoromethylaryldiazirine.

Conformational analysis of the C-terminal Gly-Leu-Met-NH2 tripeptide of substance P bound to the NK-1 receptor

Correction to Sequence-Dependent Enrichment of a Model Phosphopeptide: A Combined MALDI-TOF and NMR Study

Dermorphin and related peptides in rat tissues

Different membrane behaviour and cellular uptake of three basic arginine-rich peptides

Differential contribution of C-terminal regions of dermorphin and dermenkephalin to opioid-sites selection and binding potency.

Direct translocation of cell-penetrating peptides in liposomes: A combined mass spectrometry quantification and fluorescence detection study ⬇️

ECL1i, d(LGTFLKC), a novel, small peptide that specifically inhibits CCL2-dependent migration.

ERα17p, a peptide reproducing the hinge region of the estrogen receptor α associates to biological membranes: A biophysical approach

Exploiting Benzophenone Photoreactivity To Probe the Phospholipid Environment and Insertion Depth of the Cell-Penetrating Peptide Penetratin in Model Membranes

Further Delineation of the Two Binding Sites (R*n) Associated with Tachykinin Neurokinin-1 Receptors Using [3-Prolinomethionine11]SP Analogues

Glycosylated cell-penetrating peptides and their conjugates to a proapoptotic peptide: preparation by click chemistry and cell viability studies.

Graftable SCoMPIs enable the labeling and X-ray fluorescence imaging of proteins.

Head to tail cyclisation of cell-penetrating peptides: impact on GAG-dependent internalisation and direct translocation

High Affinity Binding of [3H]Propionyl-[Met(O2)11]Substance P(7–11), a Tritiated Septide-Like Peptide, in Chinese Hamster Ovary Cells Expressing Human Neurokinin-1 Receptors and in Rat Submandibular Glands ⬇️

Homeoproteins and homeoprotein-derived peptides: going in and out.

Incorporation of vinylogous scaffolds in the C-terminal tripeptide of substance P.

Interaction of the Anti-Proliferative GPER Inverse Agonist ERα17p with the Breast Cancer Cell Plasma Membrane: From Biophysics to Biology

Internalization of [3H]substance P analogues in NK-1 receptor transfected CHO cells.

Involvement of the second extracellular loop (E2) of the neurokinin-1 receptor in the binding of substance P. Photoaffinity labeling and modeling studies

Ionpair-π interactions favor cell penetration of arginine/tryptophan-rich cell-penetrating peptides

Is there anybody in there? On the mechanisms of wall crossing of cell penetrating peptides.

Isolation of dermenkephalin from amphibian skin, a high-affinity delta-selective opioid heptapeptide containing a D-amino acid residue.

Isotope and affinity tags in photoreactive substance P analogues to identify the covalent linkage within the NK-1 receptor by MALDI-TOF analysis.

Label-free measurement of histone lysine methyltransferases activity by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

Lipid reorganization induced by membrane-active peptides probed using differential scanning calorimetry.

MALDI-TOF mass spectrometry analysis of amphipol-trapped membrane proteins.

MALDI-TOF mass spectrometry: a powerful tool to study the internalization of cell-penetrating peptides

Massive glycosaminoglycan-dependent entry of Trp-containing cell-penetrating peptides induced by exogenous sphingomyelinase or cholesterol depletion

Membrane Crossing and Membranotropic Activity of Cell-Penetrating Peptides: Dangerous Liaisons?

Membrane interaction and perturbation mechanisms induced by two cationic cell penetrating peptides with distinct charge distribution.

Membrane interactions of two arginine-rich peptides with different cell internalization capacities

Met174 side chain is the site of photoinsertion of a substance P competitive peptide antagonist photoreactive in position 8.

Molecular partners for interaction and cell internalization of cell-penetrating peptides: how identical are they?

N- and Calpha-methylation in biologically active peptides: synthesis, structural and functional aspects.

Opioid activity of dermenkephalin analogues in the guinea-pig myenteric plexus and the hamster vas deferens.

Pachymodulin, a new functional formyl peptide receptor 2 peptidic ligand isolated from frog skin has Janus-like immunomodulatory capacities.

Peptide-grafted nanodiamonds: preparation, cytotoxicity and uptake in cells.

Peptidoglycan potentiates the membrane disrupting effect of the carboxyamidated form of DMS-DA6, a Gram-positive selective antimicrobial peptide isolated from Pachymedusa dacnicolor skin

Photocontrol of the translocation of molecules, peptides, and quantum dots through cell and lipid membranes doped with azobenzene copolymers.

Probing the in-air growth of large area of 3D functional structures into a 2D supramolecular nanoporous network

Proteomic comparison of the EWS-FLI1 expressing cells EF with NIH-3T3 and actin remodeling effect of (R/W)9 cell-penetrating peptide.

Quantification of the cellular uptake of cell-penetrating peptides by MALDI-TOF mass spectrometry

Quantification of the efficiency of cargo delivery by peptidic and pseudo-peptidic Trojan carriers using MALDI-TOF mass spectrometry

Quantitative fluorescence spectroscopy and flow cytometry analyses of cell-penetrating peptides internalization pathways: optimization, pitfalls, comparison with mass spectrometry quantification

Relationships between membrane binding, affinity and cell internalization efficacy of a cell-penetrating peptide: penetratin as a case study.

Self-assembling mini cell-penetrating peptides enter by both direct translocation and glycosaminoglycan-dependent endocytosis.

Sequence-dependent enrichment of a model phosphopeptide: a combined MALDI-TOF and NMR study

Small AntiMicrobial Peptide With in Vivo Activity Against Sepsis.

Structural and biological effects of a β2- or β3-amino acid insertion in a peptide

Structure and Dynamics of an Intrinsically Disordered Protein Region That Partially Folds upon Binding by Chemical-Exchange NMR.

Study of CPP Mechanisms by Mass Spectrometry

Tachykinin NK-1 receptor probed with constrained analogues of substance P.

The aspartic acid in deltorphin I and dermenkephalin promotes targeting to delta-opioid receptor independently of receptor binding

The human sperm protein PH-20 has hyaluronidase activity.

The interaction of cell-penetrating peptides with lipid model systems and subsequent lipid reorganization: thermodynamic and structural characterization.

The role of tryptophans on the cellular uptake and membrane interaction of arginine-rich cell penetrating peptides.

The two NK-1 binding sites correspond to distinct, independent, and non-interconvertible receptor conformational states as confirmed by plasmon-waveguide resonance spectroscopy.

Tracking a new cell-penetrating (W/R) nonapeptide, through an enzyme-stable mass spectrometry reporter tag.

Translocation and endocytosis for cell-penetrating peptide internalization

Tryptophan within basic peptide sequences triggers glycosaminoglycan-dependent endocytosis.

V(H)H (nanobody) directed against human glycophorin A: a tool for autologous red cell agglutination assays