Lista de obras - Rosa Marina Melillo - Dominio Público Uruguay

A cell proliferation and chromosomal instability signature in anaplastic thyroid carcinoma.

artículo científico publicado en 2007

A new germline RET mutation apparently devoid of transforming activity serendipitously discovered in a patient with atrophic autoimmune thyroiditis and primary ovarian failure.

artículo científico publicado en 2004

AXL Is a Novel Predictive Factor and Therapeutic Target for Radioactive Iodine Refractory Thyroid Cancer

scientific article published on 07 June 2019

Activation of the Erk8 mitogen-activated protein (MAP) kinase by RET/PTC3, a constitutively active form of the RET proto-oncogene.

artículo científico publicado en 2006

BRAF is a therapeutic target in aggressive thyroid carcinoma.

artículo científico publicado en 2006

Biochemical and molecular characterization of the novel BRAF(V599Ins) mutation detected in a classic papillary thyroid carcinoma.

artículo científico publicado en 2006

CXC chemokine receptor 4 immunodetection in the follicular variant of papillary thyroid carcinoma: comparison to galectin-3 and hector battifora mesothelial cell-1.

artículo científico publicado en 2010

Different mutations of the RET gene cause different human tumoral diseases.

artículo científico publicado en 1999

Differential diagnosis of thyroid nodules using fine-needle aspiration cytology and oncogene mutation screening: are we ready?

artículo científico publicado en 2010

Docking protein FRS2 links the protein tyrosine kinase RET and its oncogenic forms with the mitogen-activated protein kinase signaling cascade

artículo científico publicado en 2001

Efficient inhibition of RET/papillary thyroid carcinoma oncogenic kinases by 4-amino-5-(4-chloro-phenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine (PP2).

artículo científico publicado en 2003

Genetics: The genomic landscape of papillary thyroid carcinoma

artículo científico publicado en 2014

Glial cell line-derived neurotrophic factor differentially stimulates ret mutants associated with the multiple endocrine neoplasia type 2 syndromes and Hirschsprung's disease.

artículo científico publicado en 1998

HMGA2 induces pituitary tumorigenesis by enhancing E2F1 activity

artículo científico publicado en 2006

Helicobacter pylori Hp(2-20) promotes migration and proliferation of gastric epithelial cells by interacting with formyl peptide receptors in vitro and accelerates gastric mucosal healing in vivo.

artículo científico publicado en 2009

Higher intratumoral expression of CD1a, tryptase, and CD68 in a follicular variant of papillary thyroid carcinoma compared to adenomas: correlation with clinical and pathological parameters

scientific article published on 18 October 2011

Indoleamine 2,3-dioxygenase 1 (IDO1) is up-regulated in thyroid carcinoma and drives the development of an immunosuppressant tumor microenvironment.

artículo científico publicado en 2014

Mast cells have a protumorigenic role in human thyroid cancer ⬇️

artículo científico publicado el 23 de agosto de 2010

Mast cells induce epithelial-to-mesenchymal transition and stem cell features in human thyroid cancer cells through an IL-8-Akt-Slug pathway.

artículo científico publicado en 2015

Molecular biology of the MEN2 gene.

artículo científico publicado en 1998

Molecular biomarkers in thyroid FNA samples

artículo científico publicado en 2012

OPN/CD44v6 overexpression in laryngeal dysplasia and correlation with clinical outcome.

artículo científico publicado en 2007

Osteopontin is overexpressed in human papillary thyroid carcinomas and enhances thyroid carcinoma cell invasiveness.

artículo científico publicado en 2005

Overexpression of the cytokine osteopontin identifies aggressive laryngeal squamous cell carcinomas and enhances carcinoma cell proliferation and invasiveness.

artículo científico publicado en 2005

Protein kinase Calpha activation by RET: evidence for a negative feedback mechanism controlling RET tyrosine kinase.

artículo científico publicado en 2003

RET/PTC1 oncogene signaling in PC Cl 3 thyroid cells requires the small GTP-binding protein Rho.

artículo científico publicado en 2001

RET/papillary thyroid carcinoma oncogenic signaling through the Rap1 small GTPase.

artículo científico

Ras-mediated apoptosis of PC CL 3 rat thyroid cells induced by RET/PTC oncogenes

artículo científico publicado en 2003

Recent advances in understanding immune phenotypes of thyroid carcinomas: prognostication and emerging therapies

artículo científico publicado en 2019

Regulation of p27Kip1 protein levels contributes to mitogenic effects of the RET/PTC kinase in thyroid carcinoma cells.

artículo científico publicado en 2004

Serum soluble ST2 and interleukin-33 levels in patients with pulmonary arterial hypertension

The RET/PTC-RAS-BRAF linear signaling cascade mediates the motile and mitogenic phenotype of thyroid cancer cells

artículo científico publicado en 2005

The formyl peptide receptor 1 exerts a tumor suppressor function in human gastric cancer by inhibiting angiogenesis.

artículo científico publicado en 2014

The insulin receptor substrate (IRS)-1 recruits phosphatidylinositol 3-kinase to Ret: evidence for a competition between Shc and IRS-1 for the binding to Ret.

artículo científico publicado en 2001

The neuron-specific Rai (ShcC) adaptor protein inhibits apoptosis by coupling Ret to the phosphatidylinositol 3-kinase/Akt signaling pathway.

artículo científico publicado en 2002

The receptor-type protein tyrosine phosphatase J antagonizes the biochemical and biological effects of RET-derived oncoproteins

artículo científico publicado en 2006

The ret/ptc1 oncogene is activated in familial adenomatous polyposis-associated thyroid papillary carcinomas

artículo científico publicado en 1998

Thyroid cancer and inflammation

artículo científico publicado en 2009

Thyroid targeting of the N-ras(Gln61Lys) oncogene in transgenic mice results in follicular tumors that progress to poorly differentiated carcinomas

scientific article published on 19 June 2006

Tyrosine kinase oncoprotein, RET/PTC3, induces the secretion of myeloid growth and chemotactic factors.

artículo científico publicado en 2003

XB130, a tissue-specific adaptor protein that couples the RET/PTC oncogenic kinase to PI 3-kinase pathway.

artículo científico publicado en 2008

Lista de obras de Rosa Marina Melillo

A cell proliferation and chromosomal instability signature in anaplastic thyroid carcinoma.

A new germline RET mutation apparently devoid of transforming activity serendipitously discovered in a patient with atrophic autoimmune thyroiditis and primary ovarian failure.

AXL Is a Novel Predictive Factor and Therapeutic Target for Radioactive Iodine Refractory Thyroid Cancer

Activation of the Erk8 mitogen-activated protein (MAP) kinase by RET/PTC3, a constitutively active form of the RET proto-oncogene.

BRAF is a therapeutic target in aggressive thyroid carcinoma.

Biochemical and molecular characterization of the novel BRAF(V599Ins) mutation detected in a classic papillary thyroid carcinoma.

CXC chemokine receptor 4 immunodetection in the follicular variant of papillary thyroid carcinoma: comparison to galectin-3 and hector battifora mesothelial cell-1.

Different mutations of the RET gene cause different human tumoral diseases.

Differential diagnosis of thyroid nodules using fine-needle aspiration cytology and oncogene mutation screening: are we ready?

Docking protein FRS2 links the protein tyrosine kinase RET and its oncogenic forms with the mitogen-activated protein kinase signaling cascade

Efficient inhibition of RET/papillary thyroid carcinoma oncogenic kinases by 4-amino-5-(4-chloro-phenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine (PP2).

Genetics: The genomic landscape of papillary thyroid carcinoma

Glial cell line-derived neurotrophic factor differentially stimulates ret mutants associated with the multiple endocrine neoplasia type 2 syndromes and Hirschsprung's disease.

HMGA2 induces pituitary tumorigenesis by enhancing E2F1 activity

Helicobacter pylori Hp(2-20) promotes migration and proliferation of gastric epithelial cells by interacting with formyl peptide receptors in vitro and accelerates gastric mucosal healing in vivo.

Higher intratumoral expression of CD1a, tryptase, and CD68 in a follicular variant of papillary thyroid carcinoma compared to adenomas: correlation with clinical and pathological parameters

Indoleamine 2,3-dioxygenase 1 (IDO1) is up-regulated in thyroid carcinoma and drives the development of an immunosuppressant tumor microenvironment.

Mast cells have a protumorigenic role in human thyroid cancer ⬇️

Mast cells induce epithelial-to-mesenchymal transition and stem cell features in human thyroid cancer cells through an IL-8-Akt-Slug pathway.

Molecular biology of the MEN2 gene.

Molecular biomarkers in thyroid FNA samples

OPN/CD44v6 overexpression in laryngeal dysplasia and correlation with clinical outcome.

Osteopontin is overexpressed in human papillary thyroid carcinomas and enhances thyroid carcinoma cell invasiveness.

Overexpression of the cytokine osteopontin identifies aggressive laryngeal squamous cell carcinomas and enhances carcinoma cell proliferation and invasiveness.

Protein kinase Calpha activation by RET: evidence for a negative feedback mechanism controlling RET tyrosine kinase.

RET/PTC1 oncogene signaling in PC Cl 3 thyroid cells requires the small GTP-binding protein Rho.

RET/papillary thyroid carcinoma oncogenic signaling through the Rap1 small GTPase.

Ras-mediated apoptosis of PC CL 3 rat thyroid cells induced by RET/PTC oncogenes

Recent advances in understanding immune phenotypes of thyroid carcinomas: prognostication and emerging therapies

Regulation of p27Kip1 protein levels contributes to mitogenic effects of the RET/PTC kinase in thyroid carcinoma cells.

Serum soluble ST2 and interleukin-33 levels in patients with pulmonary arterial hypertension

The RET/PTC-RAS-BRAF linear signaling cascade mediates the motile and mitogenic phenotype of thyroid cancer cells

The formyl peptide receptor 1 exerts a tumor suppressor function in human gastric cancer by inhibiting angiogenesis.

The insulin receptor substrate (IRS)-1 recruits phosphatidylinositol 3-kinase to Ret: evidence for a competition between Shc and IRS-1 for the binding to Ret.

The neuron-specific Rai (ShcC) adaptor protein inhibits apoptosis by coupling Ret to the phosphatidylinositol 3-kinase/Akt signaling pathway.

The receptor-type protein tyrosine phosphatase J antagonizes the biochemical and biological effects of RET-derived oncoproteins

The ret/ptc1 oncogene is activated in familial adenomatous polyposis-associated thyroid papillary carcinomas

Thyroid cancer and inflammation

Thyroid targeting of the N-ras(Gln61Lys) oncogene in transgenic mice results in follicular tumors that progress to poorly differentiated carcinomas

Tyrosine kinase oncoprotein, RET/PTC3, induces the secretion of myeloid growth and chemotactic factors.

XB130, a tissue-specific adaptor protein that couples the RET/PTC oncogenic kinase to PI 3-kinase pathway.