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12-Lipoxygenase-knockout mice are resistant to inflammatory effects of obesity induced by Western diet

artículo científico publicado en 2008

A Putative Prohibitin-Calcium Nexus in <i>β</i>-Cell Mitochondria and Diabetes

artículo científico publicado en 2020

A novel fluorescence imaging approach for comparative measurements of pancreatic islet function in vitro

artículo científico publicado el 1 de enero de 2011

A practical guide to rodent islet isolation and assessment

artículo científico publicado en 2009

AGI-1067, a novel antioxidant and anti-inflammatory agent, enhances insulin release and protects mouse islets

artículo científico publicado en 2010

An Automated Perifusion System for Modifying Cell Culture Conditions over Time

artículo científico publicado en 2016

An Islet-Targeted Genome-Wide Association Scan Identifies Novel Genes Implicated in Cytokine-Mediated Islet Stress in Type 2 Diabetes

artículo científico publicado en 2015

Apolipoprotein A-IV improves glucose homeostasis by enhancing insulin secretion

artículo científico publicado en 2012

Calcium current subtypes in GnRH neurons

artículo científico publicado en 2003

Chronic stimulation induces adaptive potassium channel activity that restores calcium oscillations in pancreatic islets in vitro

artículo científico publicado en 2020

Circulating Levels of IL-1B+IL-6 Cause ER Stress and Dysfunction in Islets From Prediabetic Male Mice

artículo científico publicado el 8 de julio de 2013

Combined treatment with lisofylline and exendin-4 reverses autoimmune diabetes

artículo científico publicado en 2006

Comparison of metabolic oscillations from mouse pancreatic beta cells and islets

artículo científico publicado en 2004

Connexin-36 gap junctions regulate in vivo first- and second-phase insulin secretion dynamics and glucose tolerance in the conscious mouse

artículo científico publicado en 2012

Considerations for Defining Cytokine Dose, Duration, and Milieu That Are Appropriate for Modeling Chronic Low-Grade Inflammation in Type 2 Diabetes

artículo científico publicado en 2016

Dose-dependent switch in response of gonadotropin-releasing hormone (GnRH) neurons to GnRH mediated through the type I GnRH receptor

artículo científico publicado en 2003

Episodic hormone secretion: a comparison of the basis of pulsatile secretion of insulin and GnRH.

artículo científico publicado en 2014

Estradiol-sensitive afferents modulate long-term episodic firing patterns of GnRH neurons

artículo científico publicado en 2002

Evidence of diminished glucose stimulation and endoplasmic reticulum function in nonoscillatory pancreatic islets

artículo científico publicado en 2008

Evidence that low-grade systemic inflammation can induce islet dysfunction as measured by impaired calcium handling

artículo científico publicado el 25 de agosto de 2010

Glucose metabolism, islet architecture, and genetic homogeneity in imprinting of [Ca2+](i) and insulin rhythms in mouse islets

artículo científico publicado en 2009

Glucose modulates [Ca2+]i oscillations in pancreatic islets via ionic and glycolytic mechanisms

artículo científico publicado en 2006

Glucose-induced release of nitric oxide from mouse pancreatic islets as detected with nitric oxide-selective glass microelectrodes

artículo científico publicado en 2006

Gonadotropin-releasing hormone neurons generate interacting rhythms in multiple time domains

artículo científico publicado en 2003

Increased serum CXCL1 and CXCL5 are linked to obesity, hyperglycemia, and impaired islet function

artículo científico publicado en 2014

Individual mice can be distinguished by the period of their islet calcium oscillations: is there an intrinsic islet period that is imprinted in vivo?

artículo científico publicado en 2005

Insulin feedback alters mitochondrial activity through an ATP-sensitive K+ channel-dependent pathway in mouse islets and beta-cells

artículo científico publicado en 2004

Insulin secretion in the conscious mouse is biphasic and pulsatile

artículo científico publicado en 2005

Intact pancreatic islets and dispersed beta-cells both generate intracellular calcium oscillations but differ in their responsiveness to glucose

scientific article published on 16 September 2019

Islet Hypersensitivity to Glucose Is Associated With Disrupted Oscillations and Increased Impact of Proinflammatory Cytokines in Islets From Diabetes-Prone Male Mice

artículo científico publicado en 2016

Manganese-Enhanced Magnetic Resonance Imaging Detects Declining Pancreatic β-Cell Mass in a Cyclophosphamide-Accelerated Mouse Model of Type 1 Diabetes

artículo científico publicado el 29 de agosto de 2012

Mechanisms underlying episodic gonadotropin-releasing hormone secretion

artículo científico publicado en 2003

Metformin Inhibits Mouse Islet Insulin Secretion and Alters Intracellular Calcium in a Concentration-Dependent and Duration-Dependent Manner near the Circulating Range.

artículo científico publicado en 2018

Nonobese diabetic (NOD) mice congenic for a targeted deletion of 12/15-lipoxygenase are protected from autoimmune diabetes

artículo científico publicado en 2007

Peroxisome proliferator-activated receptor gamma activation restores islet function in diabetic mice through reduction of endoplasmic reticulum stress and maintenance of euchromatin structure

artículo científico publicado en 2009

Prenatal androgen exposure programs metabolic dysfunction in female mice

artículo científico publicado en 2010

Resolving the conundrum of islet transplantation by linking metabolic dysregulation, inflammation, and immune regulation

artículo científico publicado en 2008

STEAP4 expression in human islets is associated with differences in body mass index, sex, HbA1c, and inflammation.

artículo científico publicado en 2017

Salivary gland hypofunction induced by activation of innate immunity is dependent on type I interferon signaling

artículo científico publicado el 5 de junio de 2012

Steroid regulation of GnRH neurons

artículo científico publicado en 2003

Stress-induced dissociations between intracellular calcium signaling and insulin secretion in pancreatic islets

artículo científico publicado en 2015

The central role of calcium in the effects of cytokines on beta-cell function: implications for type 1 and type 2 diabetes

artículo científico publicado en 2011

The unique hypusine modification of eIF5A promotes islet beta cell inflammation and dysfunction in mice

artículo científico publicado en 2010

Valsartan protects pancreatic islets and adipose tissue from the inflammatory and metabolic consequences of a high-fat diet in mice

artículo científico publicado en 2010

Vesicular nucleotide transporter-mediated ATP release regulates insulin secretion

artículo científico publicado en 2012

Zinc Transport Gets Its Zing Back: Double-Knockout of ZnT7 and ZnT8 Reveals the Importance of Zinc Transporters to Insulin Secretion.

artículo científico publicado en 2016