Lista de obras - Martin Villalba - Dominio Público Uruguay

5' and 3' untranslated regions contribute to the differential expression of specific HLA-A alleles

scientific article published on 13 October 2015

A novel functional interaction between Vav and PKCtheta is required for TCR-induced T cell activation.

artículo científico publicado en 2000

A possible role for PKCδ in cerebellar granule cells apoptosis ⬇️

artículo científico publicado el 13 de julio de 1998

Activated Allogeneic NK Cells Preferentially Kill Poor Prognosis B-Cell Chronic Lymphocytic Leukemia Cells.

artículo científico publicado en 2016

Activation of microglial cells by beta-amyloid protein and interferon-gamma.

artículo científico publicado en 1995

Age-related changes in calcium homeostatic mechanisms in synaptosomes in relation with working memory deficiency.

artículo científico publicado en 1993

All-trans retinoic acid (ATRA) induces miR-23a expression, decreases CTSC expression and granzyme B activity leading to impaired NK cell cytotoxicity

artículo científico publicado en 2014

Altered cell calcium regulation in synaptosomes and brain cells of the 30-month-old rat: prominent effects in hippocampus

scientific article published on 01 September 1995

CD45 Isoform Profile Identifies Natural Killer (NK) Subsets with Differential Activity.

artículo científico publicado en 2016

Chemical metabolic inhibitors for the treatment of blood-borne cancers

artículo científico publicado en 2014

Concomitant induction of apoptosis and necrosis in cerebellar granule cells following serum and potassium withdrawal.

artículo científico publicado en 1997

Controlled Epstein-Barr virus reactivation after allogeneic transplantation is associated with improved survival.

artículo científico publicado en 2014

Dissecting the NK Cell Population in Hematological Cancers Confirms the Presence of Tumor Cells and Their Impact on NK Population Function

artículo científico publicado en 2020

Distinct functions of Vav1 in JNK1 activation in Jurkat T cells versus non-haematopoietic cells.

artículo científico publicado en 2004

ERK5 activates NF-kappaB in leukemic T cells and is essential for their growth in vivo.

artículo científico publicado en 2006

ERK5 knockdown generates mouse leukemia cells with low MHC class I levels that activate NK cells and block tumorigenesis.

artículo científico publicado en 2009

Expansion of allogeneic NK cells with efficient antibody-dependent cell cytotoxicity against multiple tumors

scientific article published on 14 June 2018

Extracellular-signal-regulated kinase 5 modulates the antioxidant response by transcriptionally controlling Sirtuin 1 expression in leukemic cells.

artículo científico publicado en 2014

From tumor cell metabolism to tumor immune escape ⬇️

artículo científico publicado el 5 de mayo de 2012

Guanine exchange-dependent and -independent effects of Vav1 on integrin-induced T cell spreading

artículo científico publicado en 2003

Human Leukemic Cells performing Oxidative Phosphorylation (OXPHOS) Generate an Antioxidant Response Independently of Reactive Oxygen species (ROS) Production

artículo científico publicado en 2015

Human NK cells activated by EBV(+) lymphoblastoid cells overcome anti-apoptotic mechanisms of drug resistance in haematological cancer cells.

artículo científico publicado en 2015

IFNα signaling through PKC-θ is essential for antitumor NK cell function

artículo científico publicado en 2014

Identification of Anti-tumor Cells Carrying Natural Killer (NK) Cell Antigens in Patients With Hematological Cancers

artículo científico publicado en 2015

Impaired anti-leukemic immune response in PKCtheta-deficient mice

artículo científico publicado en 2008

Insulin-like growth factor-I modulation of cerebellar cell populations is developmentally stage-dependent and mediated by specific intracellular pathways.

artículo científico publicado en 1998

Intracellular compartmentation of pyruvate in primary cultures of cortical neurons as detected by 13C NMR spectroscopy with multiple 13C labels ⬇️

artículo científico publicado el 1 de diciembre de 2001

Lessons from the Fourth Metronomic and Anti-angiogenic Therapy Meeting, 24-25 June 2014, Milan

artículo científico publicado en 2014

MHC-I modulation due to changes in tumor cell metabolism regulates tumor sensitivity to CTL and NK cells

artículo científico publicado en 2015

Metabolic stress controls mutant p53 R248Q stability in acute myeloid leukemia cells

artículo científico publicado en 2019

Mitochondrial Complex I activity signals antioxidant response through ERK5.

artículo científico publicado en 2018

Mouse microglial cells express a plasma membrane pore gated by extracellular ATP

artículo científico publicado en 1996

Mutations in the ND2 Subunit of Mitochondrial Complex I Are Sufficient to Confer Increased Tumorigenic and Metastatic Potential to Cancer Cells

scientific article published on 21 July 2019

NF-kappa B activation induced by T cell receptor/CD28 costimulation is mediated by protein kinase C-theta

artículo científico publicado en 2000

NK cell activation and recovery of NK cell subsets in lymphoma patients after obinutuzumab and lenalidomide treatment

scientific article published on 20 December 2017

NMDA-induced increase in [Ca2+]i and 45Ca2+ uptake in acutely dissociated brain cells derived from adult rats

artículo científico publicado el 20 de enero de 1992

Non-Genetically Improving the Natural Cytotoxicity of Natural Killer (NK) Cells

artículo científico publicado en 2020

Oxidative phosphorylation induces de novo expression of the MHC class I in tumor cells through the ERK5 pathway.

artículo científico publicado en 2010

Pituitary adenylate cyclase-activating polypeptide (PACAP-38) protects cerebellar granule neurons from apoptosis by activating the mitogen-activated protein kinase (MAP kinase) pathway.

artículo científico publicado en 1997

Polyoxidonium® Activates Cytotoxic Lymphocyte Responses Through Dendritic Cell Maturation: Clinical Effects in Breast Cancer

scientific article published on 28 November 2019

Positive feedback regulation of PLCgamma1/Ca(2+) signaling by PKCtheta in restimulated T cells via a Tec kinase-dependent pathway.

artículo científico publicado en 2004

Prolactin increases cytosolic free calcium concentration in hepatocytes of lactating rats

scientific article published on 01 December 1991

Protection by pyruvate and malate against glutamate-mediated neurotoxicity.

artículo científico publicado en 1998

Protein Kinase C-θ (PKC-θ) in Natural Killer Cell Function and Anti-Tumor Immunity ⬇️

artículo científico publicado el 5 de julio de 2012

Protein kinase C-theta (PKCtheta), a potential drug target for therapeutic intervention with human T cell leukemias.

artículo científico publicado en 2002

Protein kinase C-theta (PKCtheta): it's all about location, location, location.

artículo científico publicado en 2003

Protein kinase C-theta is required for NK cell activation and in vivo control of tumor progression.

artículo científico publicado en 2009

Protein kinase C-theta mediates a selective T cell survival signal via phosphorylation of BAD

artículo científico publicado en 2001

Protein kinase ctheta cooperates with calcineurin to induce Fas ligand expression during activation-induced T cell death

artículo científico publicado en 1999

SUMOylation regulates the transcriptional activity of JunB in T lymphocytes.

artículo científico publicado en 2008

The NF-κB member p65 controls glutamine metabolism through miR-23a.

artículo científico publicado en 2012

The PDK1 Inhibitor Dichloroacetate Controls Cholesterol Homeostasis Through the ERK5/MEF2 Pathway

artículo científico publicado en 2017

The activity of synaptosomal calcium channels is inversely correlated with working memory performance in memory impaired, aged rats.

artículo científico publicado en 1994

The presence of wild type p53 in hematological cancers improves the efficacy of combinational therapy targeting metabolism

artículo científico publicado en 2015

The protooncogene Vav1 regulates murine leukemia virus-induced T-cell leukemogenesis.

artículo científico publicado en 2012

The role of ERK5 in T-cell signalling.

artículo científico publicado en 2005

The role of pyruvate in neuronal calcium homeostasis. Effects on intracellular calcium pools.

artículo científico publicado en 1994

Translocation of PKC[theta] in T cells is mediated by a nonconventional, PI3-K- and Vav-dependent pathway, but does not absolutely require phospholipase C

artículo científico publicado en 2002

Vav modulation of the Ras/MEK/ERK signaling pathway plays a role in NFAT activation and CD69 up-regulation

artículo científico publicado en 2000

Vav1/Rac-dependent actin cytoskeleton reorganization is required for lipid raft clustering in T cells ⬇️

artículo científico publicado el 29 de octubre de 2001

What came first: PKCtheta or the immune synapse?

artículo científico publicado en 2004

miR-143 interferes with ERK5 signaling, and abrogates prostate cancer progression in mice

artículo científico publicado en 2009

Lista de obras de Martin Villalba

5' and 3' untranslated regions contribute to the differential expression of specific HLA-A alleles

A novel functional interaction between Vav and PKCtheta is required for TCR-induced T cell activation.

A possible role for PKCδ in cerebellar granule cells apoptosis ⬇️

Activated Allogeneic NK Cells Preferentially Kill Poor Prognosis B-Cell Chronic Lymphocytic Leukemia Cells.

Activation of microglial cells by beta-amyloid protein and interferon-gamma.

Age-related changes in calcium homeostatic mechanisms in synaptosomes in relation with working memory deficiency.

All-trans retinoic acid (ATRA) induces miR-23a expression, decreases CTSC expression and granzyme B activity leading to impaired NK cell cytotoxicity

Altered cell calcium regulation in synaptosomes and brain cells of the 30-month-old rat: prominent effects in hippocampus

CD45 Isoform Profile Identifies Natural Killer (NK) Subsets with Differential Activity.

Chemical metabolic inhibitors for the treatment of blood-borne cancers

Concomitant induction of apoptosis and necrosis in cerebellar granule cells following serum and potassium withdrawal.

Controlled Epstein-Barr virus reactivation after allogeneic transplantation is associated with improved survival.

Dissecting the NK Cell Population in Hematological Cancers Confirms the Presence of Tumor Cells and Their Impact on NK Population Function

Distinct functions of Vav1 in JNK1 activation in Jurkat T cells versus non-haematopoietic cells.

ERK5 activates NF-kappaB in leukemic T cells and is essential for their growth in vivo.

ERK5 knockdown generates mouse leukemia cells with low MHC class I levels that activate NK cells and block tumorigenesis.

Expansion of allogeneic NK cells with efficient antibody-dependent cell cytotoxicity against multiple tumors

Extracellular-signal-regulated kinase 5 modulates the antioxidant response by transcriptionally controlling Sirtuin 1 expression in leukemic cells.

From tumor cell metabolism to tumor immune escape ⬇️

Guanine exchange-dependent and -independent effects of Vav1 on integrin-induced T cell spreading

Human Leukemic Cells performing Oxidative Phosphorylation (OXPHOS) Generate an Antioxidant Response Independently of Reactive Oxygen species (ROS) Production

Human NK cells activated by EBV(+) lymphoblastoid cells overcome anti-apoptotic mechanisms of drug resistance in haematological cancer cells.

IFNα signaling through PKC-θ is essential for antitumor NK cell function

Identification of Anti-tumor Cells Carrying Natural Killer (NK) Cell Antigens in Patients With Hematological Cancers

Impaired anti-leukemic immune response in PKCtheta-deficient mice

Insulin-like growth factor-I modulation of cerebellar cell populations is developmentally stage-dependent and mediated by specific intracellular pathways.

Intracellular compartmentation of pyruvate in primary cultures of cortical neurons as detected by 13C NMR spectroscopy with multiple 13C labels ⬇️

Lessons from the Fourth Metronomic and Anti-angiogenic Therapy Meeting, 24-25 June 2014, Milan

MHC-I modulation due to changes in tumor cell metabolism regulates tumor sensitivity to CTL and NK cells

Metabolic stress controls mutant p53 R248Q stability in acute myeloid leukemia cells

Mitochondrial Complex I activity signals antioxidant response through ERK5.

Mouse microglial cells express a plasma membrane pore gated by extracellular ATP

Mutations in the ND2 Subunit of Mitochondrial Complex I Are Sufficient to Confer Increased Tumorigenic and Metastatic Potential to Cancer Cells

NF-kappa B activation induced by T cell receptor/CD28 costimulation is mediated by protein kinase C-theta

NK cell activation and recovery of NK cell subsets in lymphoma patients after obinutuzumab and lenalidomide treatment

NMDA-induced increase in [Ca2+]i and 45Ca2+ uptake in acutely dissociated brain cells derived from adult rats

Non-Genetically Improving the Natural Cytotoxicity of Natural Killer (NK) Cells

Oxidative phosphorylation induces de novo expression of the MHC class I in tumor cells through the ERK5 pathway.

Pituitary adenylate cyclase-activating polypeptide (PACAP-38) protects cerebellar granule neurons from apoptosis by activating the mitogen-activated protein kinase (MAP kinase) pathway.

Polyoxidonium® Activates Cytotoxic Lymphocyte Responses Through Dendritic Cell Maturation: Clinical Effects in Breast Cancer

Positive feedback regulation of PLCgamma1/Ca(2+) signaling by PKCtheta in restimulated T cells via a Tec kinase-dependent pathway.

Prolactin increases cytosolic free calcium concentration in hepatocytes of lactating rats

Protection by pyruvate and malate against glutamate-mediated neurotoxicity.

Protein Kinase C-θ (PKC-θ) in Natural Killer Cell Function and Anti-Tumor Immunity ⬇️

Protein kinase C-theta (PKCtheta), a potential drug target for therapeutic intervention with human T cell leukemias.

Protein kinase C-theta (PKCtheta): it's all about location, location, location.

Protein kinase C-theta is required for NK cell activation and in vivo control of tumor progression.

Protein kinase C-theta mediates a selective T cell survival signal via phosphorylation of BAD

Protein kinase ctheta cooperates with calcineurin to induce Fas ligand expression during activation-induced T cell death

SUMOylation regulates the transcriptional activity of JunB in T lymphocytes.

The NF-κB member p65 controls glutamine metabolism through miR-23a.

The PDK1 Inhibitor Dichloroacetate Controls Cholesterol Homeostasis Through the ERK5/MEF2 Pathway

The activity of synaptosomal calcium channels is inversely correlated with working memory performance in memory impaired, aged rats.

The presence of wild type p53 in hematological cancers improves the efficacy of combinational therapy targeting metabolism

The protooncogene Vav1 regulates murine leukemia virus-induced T-cell leukemogenesis.

The role of ERK5 in T-cell signalling.

The role of pyruvate in neuronal calcium homeostasis. Effects on intracellular calcium pools.

Translocation of PKC[theta] in T cells is mediated by a nonconventional, PI3-K- and Vav-dependent pathway, but does not absolutely require phospholipase C

Vav modulation of the Ras/MEK/ERK signaling pathway plays a role in NFAT activation and CD69 up-regulation

Vav1/Rac-dependent actin cytoskeleton reorganization is required for lipid raft clustering in T cells ⬇️

What came first: PKCtheta or the immune synapse?

miR-143 interferes with ERK5 signaling, and abrogates prostate cancer progression in mice