Lista de obras - Wilbert Bitter - Dominio Público Uruguay

A Novel extracytoplasmic function (ECF) sigma factor regulates virulence in Pseudomonas aeruginosa

scientific journal article

A fluorescence-based reporter for monitoring expression of mycobacterial cytochrome bd in response to antibacterials and during infection

artículo científico publicado en 2017

A specific secretion system mediates PPE41 transport in pathogenic mycobacteria

scientific article published on 01 November 2006

A star with stripes: zebrafish as an infection model

artículo científico publicado en 2004

Accelerating early anti-tuberculosis drug discovery by creating mycobacterial indicator strains that predict mode of action.

artículo científico publicado en 2018

Analysis of SecA2-dependent substrates in Mycobacterium marinum identifies protein kinase G (PknG) as a virulence effector.

artículo científico publicado en 2013

Cell envelope stress in mycobacteria is regulated by the novel signal transduction ATPase IniR in response to trehalose.

artículo científico publicado en 2017

Characterization of five novel Pseudomonas aeruginosa cell-surface signalling systems

scientific journal article

Complete genome sequence of Mycobacterium fortuitum subsp. fortuitum type strain DSM46621

artículo científico publicado en 2012

Complete genome sequence of Mycobacterium phlei type strain RIVM601174.

artículo científico publicado en 2012

Complete genome sequence of Mycobacterium vaccae type strain ATCC 25954.

artículo científico publicado en 2012

Complete genome sequence of Mycobacterium xenopi type strain RIVM700367.

artículo científico publicado en 2012

Composition of the type VII secretion system membrane complex.

artículo científico publicado en 2012

Conserved Pro-Glu (PE) and Pro-Pro-Glu (PPE) protein domains target LipY lipases of pathogenic mycobacteria to the cell surface via the ESX-5 pathway

artículo científico publicado en 2011

Differential detergent extraction of mycobacterium marinum cell envelope proteins identifies an extensively modified threonine-rich outer membrane protein with channel activity.

artículo científico publicado en 2013

Direct visualization by cryo-EM of the mycobacterial capsular layer: a labile structure containing ESX-1-secreted proteins

artículo científico publicado en 2010

Disruption of the ESX-5 system of Mycobacterium tuberculosis causes loss of PPE protein secretion, reduction of cell wall integrity and strong attenuation

artículo científico publicado en 2012

Do mycobacteria produce endospores?

artículo científico publicado en 2009

ESX-1-mediated translocation to the cytosol controls virulence of mycobacteria

artículo científico publicado en 2012

ESX-5-deficient Mycobacterium marinum is hypervirulent in adult zebrafish.

artículo científico publicado en 2012

Engineering a self-sufficient Mycobacterium tuberculosis CYP130 by gene fusion with the reductase-domain of CYP102A1 from Bacillus megaterium.

artículo científico publicado en 2017

Environmental Mycobacterium avium subsp. hominissuis have a higher probability to act as a recipient in conjugation than clinical strains.

artículo científico publicado en 2018

EspH is a hypervirulence factor for Mycobacterium marinum and essential for the secretion of the ESX-1 substrates EspE and EspF

artículo científico publicado en 2018

Essential Role of the ESX-5 Secretion System in Outer Membrane Permeability of Pathogenic Mycobacteria

artículo científico publicado en 2015

Expression analysis of the Toll-like receptor and TIR domain adaptor families of zebrafish

artículo científico publicado en 2004

Fine-mapping the contact sites of the Escherichia coli cell division proteins FtsB and FtsL on the FtsQ protein

artículo científico publicado en 2013

Fluorescent Benzothiazinone Analogues Efficiently and Selectively Label Dpre1 in Mycobacteria and Actinobacteria

scholarly article by Raphael Sommer et al published 5 October 2018 in ACS Chemical Biology

Formation of oligomeric rings by XcpQ and PilQ, which are involved in protein transport across the outer membrane of Pseudomonas aeruginosa ⬇️

artículo científico publicado el 1 de enero de 1998

Function, essentiality, and expression of cytochrome P450 enzymes and their cognate redox partners in Mycobacterium tuberculosis: are they drug targets?

artículo científico publicado en 2019

Functional dissection of the PE domain responsible for translocation of PE_PGRS33 across the mycobacterial cell wall

artículo científico publicado en 2011

General secretion signal for the mycobacterial type VII secretion pathway

artículo científico publicado en 2012

Genome-wide transposon mutagenesis indicates that Mycobacterium marinum customizes its virulence mechanisms for survival and replication in different hosts

artículo científico publicado en 2015

Genomic expression catalogue of a global collection of BCG vaccine strains show evidence for highly diverged metabolic and cell-wall adaptations

artículo científico publicado en 2015

Getting across the cell envelope: mycobacterial protein secretion

artículo científico publicado en 2013

Identification and real-time imaging of a myc-expressing neutrophil population involved in inflammation and mycobacterial granuloma formation in zebrafish

scientific article published on 22 May 2007

Identification of a novel conjugative plasmid in mycobacteria that requires both type IV and type VII secretion

artículo científico publicado en 2014

Identification of a substrate domain that determines system specificity in mycobacterial type VII secretion systems

artículo científico publicado en 2017

Identification of gene fusion events in <i>Mycobacterium tuberculosis</i> that encode chimeric proteins

artículo científico publicado en 2020

Impact of protein domains on PE_PGRS30 polar localization in Mycobacteria

artículo científico publicado en 2014

Infection of zebrafish embryos with live fluorescent Streptococcus pneumoniae as a real-time pneumococcal meningitis model.

artículo científico publicado en 2016

Inorganic Phosphate Limitation Modulates Capsular Polysaccharide Composition in Mycobacteria

artículo científico publicado en 2016

Integrated transcriptomic and proteomic analysis of pathogenic mycobacteria and their esx-1 mutants reveal secretion-dependent regulation of ESX-1 substrates and WhiB6 as a transcriptional regulator

scientific article published in PLoS ONE

Linking cytochrome P450 enzymes from Mycobacterium tuberculosis to their cognate ferredoxin partners

artículo científico publicado en 2018

Mannan core branching of lipo(arabino)mannan is required for mycobacterial virulence in the context of innate immunity

artículo científico publicado en 2013

Methanotrophy by a Mycobacterium species that dominates a cave microbial ecosystem

artículo científico publicado en 2022

Modeling tuberculous meningitis in zebrafish using Mycobacterium marinum.

artículo científico publicado en 2014

Modification of a PE/PPE substrate pair reroutes an Esx substrate pair from the mycobacterial ESX-1 type VII secretion system to the ESX-5 system

artículo científico publicado en 2020

Molecular patchwork: Chromosomal recombination between two Helicobacter pylori strains during natural colonization

artículo científico publicado en 2003

Mutagenesis-Based Characterization and Improvement of a Novel Inclusion Body Tag

artículo científico publicado en 2019

Mutations in ppe38 block PE_PGRS secretion and increase virulence of Mycobacterium tuberculosis

artículo científico publicado en 2018

Mycobacteria employ two different mechanisms to cross the blood-brain barrier

artículo científico publicado en 2018

Mycobacterial secretion systems ESX-1 and ESX-5 play distinct roles in host cell death and inflammasome activation

artículo científico publicado en 2011

Mycobacterium marinum MMAR_2380, a predicted transmembrane acyltransferase, is essential for the presence of the mannose cap on lipoarabinomannan ⬇️

artículo científico publicado en 2010

Mycobacterium marinum strains can be divided into two distinct types based on genetic diversity and virulence

artículo científico publicado en 2004

Mycosins Are Required for the Stabilization of the ESX-1 and ESX-5 Type VII Secretion Membrane Complexes

artículo científico publicado en 2016

Optimization of secretion and surface localization of heterologous OVA protein in mycobacteria by using LipY as a carrier

artículo científico publicado en 2019

PPE and PE_PGRS proteins ofMycobacterium marinumare transported via the type VII secretion system ESX-5

artículo científico publicado en 2009

PPE38-Secretion-Dependent Proteins of <i>M. tuberculosis</i> Alter NF-kB Signalling and Inflammatory Responses in Macrophages

artículo científico publicado en 2021

Pathogens under stress

artículo científico publicado en 2014

Phagosomal rupture by Mycobacterium tuberculosis results in toxicity and host cell death

artículo científico publicado en 2012

Processing of cell-surface signalling anti-sigma factors prior to signal recognition is a conserved autoproteolytic mechanism that produces two functional domains

artículo científico publicado en 2015

Protease domain and transmembrane domain of the type VII secretion mycosin protease determine system-specific functioning in mycobacteria

scientific article published on 28 January 2019

RD5-mediated lack of PE_PGRS and PPE-MPTR export in BCG vaccine strains results in strong reduction of antigenic repertoire but little impact on protection.

artículo científico publicado en 2018

Recombinant BCG Expressing ESX-1 of Mycobacterium marinum Combines Low Virulence with Cytosolic Immune Signaling and Improved TB Protection

artículo científico publicado en 2017

Role for Escherichia coli YidD in membrane protein insertion

artículo científico

Role of Mycobacterium avium lysate INF-γ, IL-17, and IL-2 ELISPOT assays in diagnosing nontuberculous mycobacteria lymphadenitis in children

artículo científico publicado en 2019

Role of Pseudomonas putida tol-oprL gene products in uptake of solutes through the cytoplasmic membrane

artículo científico publicado en 2003

Role of the calcium ion and the disulfide bond in the Burkholderia glumae lipase

SecB-like chaperone controls a toxin-antitoxin stress-responsive system in Mycobacterium tuberculosis

artículo científico publicado en 2011

Secretins of Pseudomonas aeruginosa: large holes in the outer membrane

artículo científico publicado en 2003

Self-cleavage of the Pseudomonas aeruginosa Cell-surface Signaling Anti-sigma Factor FoxR Occurs through an N-O Acyl Rearrangement

artículo científico publicado en 2015

Specific chaperones for the type VII protein secretion pathway.

artículo científico publicado en 2012

Specificity of the zebrafish host transcriptome response to acute and chronic mycobacterial infection and the role of innate and adaptive immune components.

artículo científico publicado en 2009

Structure and dynamics of a mycobacterial type VII secretion system

artículo científico publicado en 2021

Structure of the Mycobacterium tuberculosis type VII secretion system chaperone EspG5 in complex with PE25-PPE41 dimer

artículo científico publicado en 2014

Structure of the mycobacterial ESX-5 type VII secretion system membrane complex by single-particle analysis.

artículo científico publicado en 2017

Sulfur Cave (Romania), an extreme environment with microbial mats in a CO2-H2S/O2 gas chemocline dominated by mycobacteria

Systematic genetic nomenclature for type VII secretion systems.

artículo científico publicado en 2009

Take five - Type VII secretion systems of Mycobacteria

artículo científico publicado en 2013

Targeting Bacterial Virulence: The Coming Out of Type VII Secretion Inhibitors

artículo científico publicado en 2014

The Ag85B protein of the BCG vaccine facilitates macrophage uptake but is dispensable for protection against aerosol Mycobacterium tuberculosis infection

artículo científico publicado en 2016

The Dienes phenomenon: competition and territoriality in Swarming Proteus mirabilis

artículo científico publicado en 2009

The ESX-5 System of Pathogenic Mycobacteria Is Involved In Capsule Integrity and Virulence through Its Substrate PPE10

artículo científico publicado en 2016

The ESX-5 secretion system of Mycobacterium marinum modulates the macrophage response

artículo científico publicado en 2008

The Prc and RseP proteases control bacterial cell-surface signalling activity

scientific journal article

The Soluble Periplasmic Domains of Escherichia coli Cell Division Proteins FtsQ/FtsB/FtsL Form a Trimeric Complex with Submicromolar Affinity

artículo científico publicado en 2015

The extracytoplasmic function sigma factor σVreI is active during infection and contributes to phosphate starvation-induced virulence of Pseudomonas aeruginosa

scientific article published on 21 February 2020

The heterologous siderophores ferrioxamine B and ferrichrome activate signaling pathways in Pseudomonas aeruginosa

scientific journal article

The mannose cap of mycobacterial lipoarabinomannan does not dominate the Mycobacterium-host interaction

artículo científico publicado en 2007

The novel antibiotic rhodomyrtone traps membrane proteins in vesicles with increased fluidity

artículo científico publicado en 2018

The outer membrane component, YscC, of the Yop secretion machinery of Yersinia enterocolitica forms a ring‐shaped multimeric complex ⬇️

artículo científico publicado el 1 de noviembre de 1997

The role of transferrin-receptor variation in the host range of Trypanosoma brucei ⬇️

artículo científico publicado el 29 de enero de 1998

Towards a new combination therapy for tuberculosis with next generation benzothiazinones

artículo científico publicado en 2014

Transmission of Mycobacterium marinum from fish to a very young child.

artículo científico publicado en 2008

Tubercle bacilli rely on a type VII army for pathogenicity

artículo científico

Type VII Secretion Substrates of Pathogenic Mycobacteria Are Processed by a Surface Protease

scientific article published on 29 October 2019

Type VII Secretion: A Highly Versatile Secretion System

artículo científico publicado en 2016

Type VII secretion in mycobacteria: classification in line with cell envelope structure

artículo científico publicado en 2009

Type VII secretion--mycobacteria show the way.

artículo científico publicado en 2007

Understanding specificity of the mycosin proteases in ESX/type VII secretion by structural and functional analysis

artículo científico publicado en 2013

Unexpected link between lipooligosaccharide biosynthesis and surface protein release in Mycobacterium marinum

artículo científico publicado en 2012

Zebrafish development and regeneration: new tools for biomedical research

artículo científico publicado en 2009

Zebrafish embryo screen for mycobacterial genes involved in the initiation of granuloma formation reveals a newly identified ESX-1 component

artículo científico publicado en 2011

Zebrafish embryos as a model host for the real time analysis of Salmonella typhimurium infections

artículo científico publicado en 2003

iniBAC induction Is Vitamin B12- and MutAB-dependent in Mycobacterium marinum

artículo científico publicado en 2016

Lista de obras de Wilbert Bitter

A Novel extracytoplasmic function (ECF) sigma factor regulates virulence in Pseudomonas aeruginosa

A fluorescence-based reporter for monitoring expression of mycobacterial cytochrome bd in response to antibacterials and during infection

A specific secretion system mediates PPE41 transport in pathogenic mycobacteria

A star with stripes: zebrafish as an infection model

Accelerating early anti-tuberculosis drug discovery by creating mycobacterial indicator strains that predict mode of action.

Analysis of SecA2-dependent substrates in Mycobacterium marinum identifies protein kinase G (PknG) as a virulence effector.

Cell envelope stress in mycobacteria is regulated by the novel signal transduction ATPase IniR in response to trehalose.

Characterization of five novel Pseudomonas aeruginosa cell-surface signalling systems

Complete genome sequence of Mycobacterium fortuitum subsp. fortuitum type strain DSM46621

Complete genome sequence of Mycobacterium phlei type strain RIVM601174.

Complete genome sequence of Mycobacterium vaccae type strain ATCC 25954.

Complete genome sequence of Mycobacterium xenopi type strain RIVM700367.

Composition of the type VII secretion system membrane complex.

Conserved Pro-Glu (PE) and Pro-Pro-Glu (PPE) protein domains target LipY lipases of pathogenic mycobacteria to the cell surface via the ESX-5 pathway

Differential detergent extraction of mycobacterium marinum cell envelope proteins identifies an extensively modified threonine-rich outer membrane protein with channel activity.

Direct visualization by cryo-EM of the mycobacterial capsular layer: a labile structure containing ESX-1-secreted proteins

Disruption of the ESX-5 system of Mycobacterium tuberculosis causes loss of PPE protein secretion, reduction of cell wall integrity and strong attenuation

Do mycobacteria produce endospores?

ESX-1-mediated translocation to the cytosol controls virulence of mycobacteria

ESX-5-deficient Mycobacterium marinum is hypervirulent in adult zebrafish.

Engineering a self-sufficient Mycobacterium tuberculosis CYP130 by gene fusion with the reductase-domain of CYP102A1 from Bacillus megaterium.

Environmental Mycobacterium avium subsp. hominissuis have a higher probability to act as a recipient in conjugation than clinical strains.

EspH is a hypervirulence factor for Mycobacterium marinum and essential for the secretion of the ESX-1 substrates EspE and EspF

Essential Role of the ESX-5 Secretion System in Outer Membrane Permeability of Pathogenic Mycobacteria

Expression analysis of the Toll-like receptor and TIR domain adaptor families of zebrafish

Fine-mapping the contact sites of the Escherichia coli cell division proteins FtsB and FtsL on the FtsQ protein

Fluorescent Benzothiazinone Analogues Efficiently and Selectively Label Dpre1 in Mycobacteria and Actinobacteria

Formation of oligomeric rings by XcpQ and PilQ, which are involved in protein transport across the outer membrane of Pseudomonas aeruginosa ⬇️

Function, essentiality, and expression of cytochrome P450 enzymes and their cognate redox partners in Mycobacterium tuberculosis: are they drug targets?

Functional dissection of the PE domain responsible for translocation of PE_PGRS33 across the mycobacterial cell wall

General secretion signal for the mycobacterial type VII secretion pathway

Genome-wide transposon mutagenesis indicates that Mycobacterium marinum customizes its virulence mechanisms for survival and replication in different hosts

Genomic expression catalogue of a global collection of BCG vaccine strains show evidence for highly diverged metabolic and cell-wall adaptations

Getting across the cell envelope: mycobacterial protein secretion

Identification and real-time imaging of a myc-expressing neutrophil population involved in inflammation and mycobacterial granuloma formation in zebrafish

Identification of a novel conjugative plasmid in mycobacteria that requires both type IV and type VII secretion

Identification of a substrate domain that determines system specificity in mycobacterial type VII secretion systems

Identification of gene fusion events in <i>Mycobacterium tuberculosis</i> that encode chimeric proteins

Impact of protein domains on PE_PGRS30 polar localization in Mycobacteria

Infection of zebrafish embryos with live fluorescent Streptococcus pneumoniae as a real-time pneumococcal meningitis model.

Inorganic Phosphate Limitation Modulates Capsular Polysaccharide Composition in Mycobacteria

Integrated transcriptomic and proteomic analysis of pathogenic mycobacteria and their esx-1 mutants reveal secretion-dependent regulation of ESX-1 substrates and WhiB6 as a transcriptional regulator

Linking cytochrome P450 enzymes from Mycobacterium tuberculosis to their cognate ferredoxin partners

Mannan core branching of lipo(arabino)mannan is required for mycobacterial virulence in the context of innate immunity

Methanotrophy by a Mycobacterium species that dominates a cave microbial ecosystem

Modeling tuberculous meningitis in zebrafish using Mycobacterium marinum.

Modification of a PE/PPE substrate pair reroutes an Esx substrate pair from the mycobacterial ESX-1 type VII secretion system to the ESX-5 system

Molecular patchwork: Chromosomal recombination between two Helicobacter pylori strains during natural colonization

Mutagenesis-Based Characterization and Improvement of a Novel Inclusion Body Tag

Mutations in ppe38 block PE_PGRS secretion and increase virulence of Mycobacterium tuberculosis

Mycobacteria employ two different mechanisms to cross the blood-brain barrier

Mycobacterial secretion systems ESX-1 and ESX-5 play distinct roles in host cell death and inflammasome activation

Mycobacterium marinum MMAR_2380, a predicted transmembrane acyltransferase, is essential for the presence of the mannose cap on lipoarabinomannan ⬇️

Mycobacterium marinum strains can be divided into two distinct types based on genetic diversity and virulence

Mycosins Are Required for the Stabilization of the ESX-1 and ESX-5 Type VII Secretion Membrane Complexes

Optimization of secretion and surface localization of heterologous OVA protein in mycobacteria by using LipY as a carrier

PPE and PE_PGRS proteins ofMycobacterium marinumare transported via the type VII secretion system ESX-5

PPE38-Secretion-Dependent Proteins of <i>M. tuberculosis</i> Alter NF-kB Signalling and Inflammatory Responses in Macrophages

Pathogens under stress

Phagosomal rupture by Mycobacterium tuberculosis results in toxicity and host cell death

Processing of cell-surface signalling anti-sigma factors prior to signal recognition is a conserved autoproteolytic mechanism that produces two functional domains

Protease domain and transmembrane domain of the type VII secretion mycosin protease determine system-specific functioning in mycobacteria

RD5-mediated lack of PE_PGRS and PPE-MPTR export in BCG vaccine strains results in strong reduction of antigenic repertoire but little impact on protection.

Recombinant BCG Expressing ESX-1 of Mycobacterium marinum Combines Low Virulence with Cytosolic Immune Signaling and Improved TB Protection

Role for Escherichia coli YidD in membrane protein insertion

Role of Mycobacterium avium lysate INF-γ, IL-17, and IL-2 ELISPOT assays in diagnosing nontuberculous mycobacteria lymphadenitis in children

Role of Pseudomonas putida tol-oprL gene products in uptake of solutes through the cytoplasmic membrane

Role of the calcium ion and the disulfide bond in the Burkholderia glumae lipase

SecB-like chaperone controls a toxin-antitoxin stress-responsive system in Mycobacterium tuberculosis

Secretins of Pseudomonas aeruginosa: large holes in the outer membrane

Self-cleavage of the Pseudomonas aeruginosa Cell-surface Signaling Anti-sigma Factor FoxR Occurs through an N-O Acyl Rearrangement

Specific chaperones for the type VII protein secretion pathway.

Specificity of the zebrafish host transcriptome response to acute and chronic mycobacterial infection and the role of innate and adaptive immune components.

Structure and dynamics of a mycobacterial type VII secretion system

Structure of the Mycobacterium tuberculosis type VII secretion system chaperone EspG5 in complex with PE25-PPE41 dimer

Structure of the mycobacterial ESX-5 type VII secretion system membrane complex by single-particle analysis.

Sulfur Cave (Romania), an extreme environment with microbial mats in a CO2-H2S/O2 gas chemocline dominated by mycobacteria

Systematic genetic nomenclature for type VII secretion systems.

Take five - Type VII secretion systems of Mycobacteria