Lista de obras - Pablo Perez-Pinera - Dominio Público Uruguay

APP processing and the APP-KPI domain involvement in the amyloid cascade.

artículo científico publicado en 2005

Activating human genes with zinc finger proteins, transcription activator-like effectors and CRISPR/Cas9 for gene therapy and regenerative medicine

artículo científico publicado en 2014

Advances in targeted genome editing

artículo científico publicado en 2012

Anaplastic lymphoma kinase is activated through the pleiotrophin/receptor protein-tyrosine phosphatase beta/zeta signaling pathway: an alternative mechanism of receptor tyrosine kinase activation

artículo científico publicado en 2007

Anaplastic lymphoma kinase is expressed in different subtypes of human breast cancer.

artículo científico publicado en 2007

Biomedical applications of gene editing.

artículo científico publicado en 2016

CRISPR-SKIP: programmable gene splicing with single base editors

article

Characterization of sensory deficits in TrkB knockout mice.

artículo científico publicado en 2008

Clinical implication of Meissner`s corpuscles

artículo científico publicado en 2012

Correction of dystrophin expression in cells from Duchenne muscular dystrophy patients through genomic excision of exon 51 by zinc finger nucleases

artículo científico publicado en 2014

Damage, Healing, and Remodeling in Optogenetic Skeletal Muscle Bioactuators

artículo científico publicado en 2017

Design and integration of a problem-based biofabrication course into an undergraduate biomedical engineering curriculum.

scientific article published on 21 September 2016

Development and neuronal dependence of cutaneous sensory nerve formations: Lessons from neurotrophins

artículo científico publicado en 2010

Differential localization of Acid-sensing ion channels 1 and 2 in human cutaneus pacinian corpuscles

artículo científico publicado en 2010

Disruption of the β1L Isoform of GABP Reverses Glioblastoma Replicative Immortality in a TERT Promoter Mutation-Dependent Manner

artículo científico publicado en 2018

Engineering Synthetic Gene Circuits in Living Cells with CRISPR Technology.

artículo científico publicado en 2016

Enteric glial cells express full-length TrkB and depend on TrkB expression for normal development.

artículo científico publicado en 2009

Expression and cell localization of brain-derived neurotrophic factor and TrkB during zebrafish retinal development.

artículo científico publicado en 2010

Fyn is a downstream target of the pleiotrophin/receptor protein tyrosine phosphatase beta/zeta-signaling pathway: regulation of tyrosine phosphorylation of Fyn by pleiotrophin

artículo científico publicado en 2005

Gene targeting to the ROSA26 locus directed by engineered zinc finger nucleases

artículo científico publicado en 2011

Genome-wide specificity of DNA binding, gene regulation, and chromatin remodeling by TALE- and CRISPR/Cas9-based transcriptional activators

artículo científico publicado en 2015

Human odontoblasts express transient receptor protein and acid-sensing ion channel mechanosensor proteins

scientific article published on 10 September 2010

Hypertonicity activates GSK3beta in tumor cells

artículo científico publicado en 2006

Identification of the angiogenesis signaling domain in pleiotrophin defines a mechanism of the angiogenic switch

artículo científico publicado en 2006

Immunohistochemical profile of human pancreatic pacinian corpuscles.

artículo científico publicado en 2010

Immunotherapy for Alzheimer's disease: rational basis in ongoing clinical trials.

artículo científico publicado en 2011

In Vivo Zinc Finger Nuclease-mediated Targeted Integration of a Glucose-6-phosphatase Transgene Promotes Survival in Mice With Glycogen Storage Disease Type IA.

artículo científico publicado en 2016

Mammalian Synthetic Biology: Engineering Biological Systems.

artículo científico publicado en 2017

Multiplexed Targeted Genome Engineering Using a Universal Nuclease-Assisted Vector Integration System

artículo científico publicado en 2016

Multiplexed and programmable regulation of gene networks with an integrated RNA and CRISPR/Cas toolkit in human cells.

artículo científico publicado en 2014

Multiplexed and tunable transcriptional activation by promoter insertion using nuclease-assisted vector integration

artículo científico publicado en 2019

Plasmatic level of neurosin predicts outcome of mild cognitive impairment.

artículo científico publicado en 2008

Pleiotrophin disrupts calcium-dependent homophilic cell-cell adhesion and initiates an epithelial-mesenchymal transition

artículo científico publicado en 2006

Pleiotrophin expression during odontogenesis

artículo científico publicado en 2012

Pleiotrophin inhibits hippocampal long-term potentiation: a role of pleiotrophin in learning and memory.

artículo científico publicado en 2009

Pleiotrophin produced by multiple myeloma induces transdifferentiation of monocytes into vascular endothelial cells: a novel mechanism of tumor-induced vasculogenesis.

artículo científico publicado en 2008

Pleiotrophin regulates serine phosphorylation and the cellular distribution of beta-adducin through activation of protein kinase C

artículo científico publicado en 2005

Pleiotrophin stimulates tyrosine phosphorylation of beta-adducin through inactivation of the transmembrane receptor protein tyrosine phosphatase beta/zeta.

artículo científico publicado en 2005

Pleiotrophin, a multifunctional angiogenic factor: mechanisms and pathways in normal and pathological angiogenesis.

artículo científico publicado en 2008

Pleiotrophin, a multifunctional tumor promoter through induction of tumor angiogenesis, remodeling of the tumor microenvironment, and activation of stromal fibroblasts.

scientific article published on December 2007

Production of Functional Anti-Ebola Antibodies in Pichia pastoris.

artículo científico publicado en 2017

Prosurvival long noncoding RNA PINCR regulates a subset of p53 targets in human colorectal cancer cells by binding to Matrin 3

artículo científico publicado en 2017

Putting Non-coding RNA on Display with CRISPR.

artículo científico publicado en 2015

RNA-guided gene activation by CRISPR-Cas9-based transcription factors

artículo científico publicado en 2013

Reading frame correction by targeted genome editing restores dystrophin expression in cells from Duchenne muscular dystrophy patients.

artículo científico publicado en 2013

S-100 proteins in the human peripheral nervous system

artículo científico publicado en 2003

Scaffold-mediated lentiviral transduction for functional tissue engineering of cartilage.

artículo científico publicado en 2014

Secretion of pleiotrophin stimulates breast cancer progression through remodeling of the tumor microenvironment.

artículo científico publicado en 2007

Sodium chloride regulates Extracellular Regulated Kinase 1/2 in different tumor cell lines

artículo científico publicado en 2006

Synergistic and tunable human gene activation by combinations of synthetic transcription factors

artículo científico publicado en 2013

Synthetic biology and microbioreactor platforms for programmable production of biologics at the point-of-care

artículo científico publicado en 2016

Targeted Gene Activation Using RNA-Guided Nucleases

artículo científico publicado en 2017

Targeted Gene Knock Out Using Nuclease-Assisted Vector Integration: Hemi- and Homozygous Deletion of JAG1

artículo científico publicado en 2018

The Trk tyrosine kinase inhibitor K252a regulates growth of lung adenocarcinomas.

artículo científico publicado en 2006

The continuously evolving CRISPR barcoding toolbox

artículo científico publicado en 2018

The expression of ENa(+)C and ASIC2 proteins in Pacinian corpuscles is differently regulated by TrkB and its ligands BDNF and NT-4.

artículo científico publicado en 2009

The lamellar cells in human Meissner corpuscles express TrkB

artículo científico publicado en 2009

The neurotrophic factor pleiotrophin modulates amphetamine-seeking behaviour and amphetamine-induced neurotoxic effects: evidence from pleiotrophin knockout mice

artículo científico publicado en 2010

The receptor protein tyrosine phosphatase (RPTP)beta/zeta is expressed in different subtypes of human breast cancer

artículo científico publicado en 2007

Thymocyte depletion affects neurotrophin receptor expression in thymic stromal cells

scientific article published on 01 February 2006

TrkB is necessary for the normal development of the lung.

artículo científico publicado en 2009

Value of measuring plasmatic levels of neurosin in the diagnosis of Alzheimer's disease

artículo científico publicado en 2008

Versatile and on-demand biologics co-production in yeast.

artículo científico publicado en 2018

Lista de obras de Pablo Perez-Pinera

APP processing and the APP-KPI domain involvement in the amyloid cascade.

Activating human genes with zinc finger proteins, transcription activator-like effectors and CRISPR/Cas9 for gene therapy and regenerative medicine

Advances in targeted genome editing

Anaplastic lymphoma kinase is activated through the pleiotrophin/receptor protein-tyrosine phosphatase beta/zeta signaling pathway: an alternative mechanism of receptor tyrosine kinase activation

Anaplastic lymphoma kinase is expressed in different subtypes of human breast cancer.

Biomedical applications of gene editing.

CRISPR-SKIP: programmable gene splicing with single base editors

Characterization of sensory deficits in TrkB knockout mice.

Clinical implication of Meissner`s corpuscles

Correction of dystrophin expression in cells from Duchenne muscular dystrophy patients through genomic excision of exon 51 by zinc finger nucleases

Damage, Healing, and Remodeling in Optogenetic Skeletal Muscle Bioactuators

Design and integration of a problem-based biofabrication course into an undergraduate biomedical engineering curriculum.

Development and neuronal dependence of cutaneous sensory nerve formations: Lessons from neurotrophins

Differential localization of Acid-sensing ion channels 1 and 2 in human cutaneus pacinian corpuscles

Disruption of the β1L Isoform of GABP Reverses Glioblastoma Replicative Immortality in a TERT Promoter Mutation-Dependent Manner

Engineering Synthetic Gene Circuits in Living Cells with CRISPR Technology.

Enteric glial cells express full-length TrkB and depend on TrkB expression for normal development.

Expression and cell localization of brain-derived neurotrophic factor and TrkB during zebrafish retinal development.

Fyn is a downstream target of the pleiotrophin/receptor protein tyrosine phosphatase beta/zeta-signaling pathway: regulation of tyrosine phosphorylation of Fyn by pleiotrophin

Gene targeting to the ROSA26 locus directed by engineered zinc finger nucleases

Genome-wide specificity of DNA binding, gene regulation, and chromatin remodeling by TALE- and CRISPR/Cas9-based transcriptional activators

Human odontoblasts express transient receptor protein and acid-sensing ion channel mechanosensor proteins

Hypertonicity activates GSK3beta in tumor cells

Identification of the angiogenesis signaling domain in pleiotrophin defines a mechanism of the angiogenic switch

Immunohistochemical profile of human pancreatic pacinian corpuscles.

Immunotherapy for Alzheimer's disease: rational basis in ongoing clinical trials.

In Vivo Zinc Finger Nuclease-mediated Targeted Integration of a Glucose-6-phosphatase Transgene Promotes Survival in Mice With Glycogen Storage Disease Type IA.

Mammalian Synthetic Biology: Engineering Biological Systems.

Multiplexed Targeted Genome Engineering Using a Universal Nuclease-Assisted Vector Integration System

Multiplexed and programmable regulation of gene networks with an integrated RNA and CRISPR/Cas toolkit in human cells.

Multiplexed and tunable transcriptional activation by promoter insertion using nuclease-assisted vector integration

Plasmatic level of neurosin predicts outcome of mild cognitive impairment.

Pleiotrophin disrupts calcium-dependent homophilic cell-cell adhesion and initiates an epithelial-mesenchymal transition

Pleiotrophin expression during odontogenesis

Pleiotrophin inhibits hippocampal long-term potentiation: a role of pleiotrophin in learning and memory.

Pleiotrophin produced by multiple myeloma induces transdifferentiation of monocytes into vascular endothelial cells: a novel mechanism of tumor-induced vasculogenesis.

Pleiotrophin regulates serine phosphorylation and the cellular distribution of beta-adducin through activation of protein kinase C

Pleiotrophin stimulates tyrosine phosphorylation of beta-adducin through inactivation of the transmembrane receptor protein tyrosine phosphatase beta/zeta.

Pleiotrophin, a multifunctional angiogenic factor: mechanisms and pathways in normal and pathological angiogenesis.

Pleiotrophin, a multifunctional tumor promoter through induction of tumor angiogenesis, remodeling of the tumor microenvironment, and activation of stromal fibroblasts.

Production of Functional Anti-Ebola Antibodies in Pichia pastoris.

Prosurvival long noncoding RNA PINCR regulates a subset of p53 targets in human colorectal cancer cells by binding to Matrin 3

Putting Non-coding RNA on Display with CRISPR.

RNA-guided gene activation by CRISPR-Cas9-based transcription factors

Reading frame correction by targeted genome editing restores dystrophin expression in cells from Duchenne muscular dystrophy patients.

S-100 proteins in the human peripheral nervous system

Scaffold-mediated lentiviral transduction for functional tissue engineering of cartilage.

Secretion of pleiotrophin stimulates breast cancer progression through remodeling of the tumor microenvironment.

Sodium chloride regulates Extracellular Regulated Kinase 1/2 in different tumor cell lines

Synergistic and tunable human gene activation by combinations of synthetic transcription factors

Synthetic biology and microbioreactor platforms for programmable production of biologics at the point-of-care

Targeted Gene Activation Using RNA-Guided Nucleases

Targeted Gene Knock Out Using Nuclease-Assisted Vector Integration: Hemi- and Homozygous Deletion of JAG1

The Trk tyrosine kinase inhibitor K252a regulates growth of lung adenocarcinomas.

The continuously evolving CRISPR barcoding toolbox

The expression of ENa(+)C and ASIC2 proteins in Pacinian corpuscles is differently regulated by TrkB and its ligands BDNF and NT-4.

The lamellar cells in human Meissner corpuscles express TrkB

The neurotrophic factor pleiotrophin modulates amphetamine-seeking behaviour and amphetamine-induced neurotoxic effects: evidence from pleiotrophin knockout mice

The receptor protein tyrosine phosphatase (RPTP)beta/zeta is expressed in different subtypes of human breast cancer

Thymocyte depletion affects neurotrophin receptor expression in thymic stromal cells

TrkB is necessary for the normal development of the lung.

Value of measuring plasmatic levels of neurosin in the diagnosis of Alzheimer's disease

Versatile and on-demand biologics co-production in yeast.