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Lista de obras de Dasiel Oscar Borroto Escuela

"Neuro-semeiotics" and "free-energy minimization" suggest a unified perspective for integrative brain actions: focus on receptor heteromers and Roamer type of volume transmission

artículo científico publicado en 2014

A Transmembrane Single-Polypeptide-Chain (sc) Linker to Connect the Two G-Protein–Coupled Receptors in Tandem and the Design for an In Vivo Analysis of Their Allosteric Receptor- Receptor Interactions

A new interpretative paradigm for Conformational Protein Diseases.

artículo científico publicado en 2013

A role for galanin N-terminal fragment (1-15) in anxiety- and depression-related behaviors in rats

artículo científico publicado en 2014

A serine point mutation in the adenosine A2AR C-terminal tail reduces receptor heteromerization and allosteric modulation of the dopamine D2R.

artículo científico publicado en 2010

A2AR Transmembrane 2 Peptide Administration Disrupts the A2AR-A2AR Homoreceptor but Not the A2AR-D2R Heteroreceptor Complex: Lack of Actions on Rodent Cocaine Self-Administration

scientific article published on 03 December 2019

A2AR-D2R Heteroreceptor Complexes in Cocaine Reward and Addiction

scholarly article by Dasiel O. Borroto-Escuela et al published December 2018 in Trends in Pharmacological Sciences

Acute Cocaine Enhances Dopamine D2R Recognition and Signaling and Counteracts D2R Internalization in Sigma1R-D2R Heteroreceptor Complexes.

artículo científico publicado en 2019

Acute cocaine treatment enhances the antagonistic allosteric adenosine A2A-dopamine D2 receptor-receptor interactions in rat dorsal striatum without increasing significantly extracellular dopamine levels

scientific article published on 02 March 2020

Adenosine A2AReceptors in Substance Use Disorders: A Focus on Cocaine

artículo científico publicado en 2020

Adenosine receptor containing oligomers: their role in the control of dopamine and glutamate neurotransmission in the brain.

artículo científico publicado en 2011

Adenosine-dopamine interactions in the pathophysiology and treatment of CNS disorders.

artículo científico publicado en 2010

Agonist-induced formation of FGFR1 homodimers and signaling differ among members of the FGF family.

artículo científico publicado en 2011

Altered trafficking and unfolded protein response induction as a result of M3 muscarinic receptor impaired N-glycosylation.

artículo científico publicado en 2011

Attenuation of Oxytocin and Serotonin 2A Receptor Signaling through Novel Heteroreceptor Formation

artículo científico publicado en 2019

Basimglurant for treatment of major depressive disorder: a novel negative allosteric modulator of metabotropic glutamate receptor 5.

artículo científico publicado en 2015

Bioluminescence resonance energy transfer methods to study G protein-coupled receptor-receptor tyrosine kinase heteroreceptor complexes

artículo científico publicado en 2013

Brain Dopamine Transmission in Health and Parkinson's Disease: Modulation of Synaptic Transmission and Plasticity Through Volume Transmission and Dopamine Heteroreceptors.

artículo científico publicado en 2018

Characterization of the A2AR-D2R interface: focus on the role of the C-terminal tail and the transmembrane helices

artículo científico publicado en 2010

Characterization of the interaction between the dopamine D4 receptor, KLHL12 and β-arrestins

artículo científico publicado en 2016

Cocaine self-administration differentially affects allosteric A2A-D2 receptor-receptor interactions in the striatum. Relevance for cocaine use disorder

artículo científico publicado en 2016

Cocaine self-administration specifically increases A2AR-D2R and D2R-sigma1R heteroreceptor complexes in the rat nucleus accumbens shell. Relevance for cocaine use disorder

artículo científico publicado en 2017

Design: An assay based on single-polypeptide-chain heterodimeric A2AR/D2R and non-oligomerized fusions for in vivo analysis of their allosteric receptor-receptor interactions

Desipramine restores the alterations in circadian entrainment induced by prenatal exposure to glucocorticoids

scientific article published on 17 October 2019

Differential allosteric modulation within dopamine D2R - neurotensin NTS1R and D2R - serotonin 5-HT2AR receptor complexes gives bias to intracellular calcium signalling

scientific article published on 08 November 2019

Differential expression of muscarinic acetylcholine receptor subtypes in Jurkat cells and their signaling

artículo científico publicado en 2011

Disruption of A2AR-D2R Heteroreceptor Complexes After A2AR Transmembrane 5 Peptide Administration Enhances Cocaine Self-Administration in Rats

artículo científico publicado en 2018

Dissecting the conserved NPxxY motif of the M3 muscarinic acetylcholine receptor: critical role of Asp-7.49 for receptor signaling and multiprotein complex formation.

artículo científico publicado en 2011

Diversity and Bias through Receptor-Receptor Interactions in GPCR Heteroreceptor Complexes. Focus on Examples from Dopamine D2 Receptor Heteromerization.

artículo científico

Dopamine D1 and D2 receptor immunoreactivities in the arcuate-median eminence complex and their link to the tubero-infundibular dopamine neurons

artículo científico publicado en 2014

Dopamine D2 Receptor Supersensitivity as a Spectrum of Neurotoxicity and Status in Psychiatric Disorders.

artículo científico publicado en 2018

Dopamine D2 and 5-hydroxytryptamine 5-HT(₂A) receptors assemble into functionally interacting heteromers.

artículo científico publicado en 2010

Dopamine D2 and D4 receptor heteromerization and its allosteric receptor-receptor interactions

scientific journal article

Dopamine D2 heteroreceptor complexes and their receptor-receptor interactions in ventral striatum: novel targets for antipsychotic drugs

artículo científico publicado en 2014

Dopamine D2 receptor signaling dynamics of dopamine D2-neurotensin 1 receptor heteromers.

artículo científico publicado en 2013

Dopamine D4 receptor oligomerization--contribution to receptor biogenesis

artículo científico publicado en 2011

Dopamine heteroreceptor complexes as therapeutic targets in Parkinson's disease.

artículo científico

Dual disruption of aldehyde dehydrogenases 1 and 3 promotes functional changes in the glutathione redox system and enhances chemosensitivity in nonsmall cell lung cancer

artículo científico publicado en 2020

Dynamic modulation of FGFR1-5-HT1A heteroreceptor complexes. Agonist treatment enhances participation of FGFR1 and 5-HT1A homodimers and recruitment of β-arrestin2

scientific journal article

Effects of Long-Term Alcohol Drinking on the Dopamine D2 Receptor: Gene Expression and Heteroreceptor Complexes in the Striatum in Rats

artículo científico publicado en 2018

Enhancement of the FGFR1 signaling in the FGFR1-5-HT1A heteroreceptor complex in midbrain raphe 5-HT neuron systems. Relevance for neuroplasticity and depression.

artículo científico publicado en 2015

Evidence for the existence of FGFR1-5-HT1A heteroreceptor complexes in the midbrain raphe 5-HT system

scientific journal article

Evidence for the existence of dopamine D2-oxytocin receptor heteromers in the ventral and dorsal striatum with facilitatory receptor-receptor interactions.

artículo científico publicado en 2012

Evidence for the existence of dopamine D2R and Sigma 1 allosteric receptor-receptor interaction in the rat brain: role in brain plasticity and cocaine action.

artículo científico publicado en 2015

Evidence for the existence of the A2A-A1 heteroreceptor complex in the rat brain, and comparison of its distribution to that of the A2A-A2A homoreceptor complex.

artículo científico publicado en 2015

Existence of Brain 5-HT1A-5-HT2A Isoreceptor Complexes with Antagonistic Allosteric Receptor-Receptor Interactions Regulating 5-HT1A Receptor Recognition.

artículo científico publicado en 2017

Existence of muscarinic acetylcholine receptor (mAChR) and fibroblast growth factor receptor (FGFR) heteroreceptor complexes and their enhancement of neurite outgrowth in neural hippocampal cultures

artículo científico publicado en 2016

Extrasynaptic neurotransmission in the modulation of brain function. Focus on the striatal neuronal-glial networks.

artículo científico publicado en 2012

FGFR1-5-HT1A Heteroreceptor Complexes: Implications for Understanding and Treating Major Depression

artículo científico

Fibroblast growth factor receptor 1- 5-hydroxytryptamine 1A heteroreceptor complexes and their enhancement of hippocampal plasticity

artículo científico publicado en 2012

Fluorescence resonance energy transfer-based technologies in the study of protein-protein interactions at the cell surface

artículo científico

Functional role of striatal A2A, D2, and mGlu5 receptor interactions in regulating striatopallidal GABA neuronal transmission.

artículo científico publicado en 2016

G protein-coupled receptor heterodimerization in the brain

artículo científico publicado en 2013

G protein-coupled receptor oligomerization and brain integration: focus on adenosinergic transmission.

artículo científico

G protein-coupled receptor oligomerization for what?

artículo científico publicado en 2010

G-protein-coupled receptor type A heteromers as an emerging therapeutic target.

artículo científico publicado en 2014

G-protein-coupled receptors oligomerization: emerging signaling units and new opportunities for drug design

artículo científico

Galanin (1-15) enhancement of the behavioral effects of Fluoxetine in the forced swimming test gives a new therapeutic strategy against depression.

artículo científico publicado en 2017

Galanin (1-15) enhances the antidepressant effects of the 5-HT1A receptor agonist 8-OH-DPAT: involvement of the raphe-hippocampal 5-HT neuron system

artículo científico publicado en 2016

Galanin and neuropeptide Y interactions elicit antidepressant activity linked to neuronal precursor cells of the dentate gyrus in the ventral hippocampus

artículo científico publicado en 2020

Galanin receptor 2-neuropeptide Y Y1 receptor interactions in the amygdala lead to increased anxiolytic actions.

artículo científico publicado en 2014

Galanin receptor 2-neuropeptide Y Y1 receptor interactions in the dentate gyrus are related with antidepressant-like effects.

artículo científico publicado en 2015

Galanin receptor-1 modulates 5-hydroxtryptamine-1A signaling via heterodimerization

artículo científico publicado en 2010

Hallucinogenic 5-HT2AR agonists LSD and DOI enhance dopamine D2R protomer recognition and signaling of D2-5-HT2A heteroreceptor complexes

artículo científico publicado en 2014

Heteroreceptor Complexes and their Allosteric Receptor-Receptor Interactions as a Novel Biological Principle for Integration of Communication in the CNS: Targets for Drug Development

artículo científico publicado en 2016

IL1R2, CCR2, and CXCR4 May Form Heteroreceptor Complexes with NMDAR and D2R: Relevance for Schizophrenia

artículo científico publicado en 2017

Increase of the FGFR1 signaling in the FGFR1-5-HT1A heteroreceptor complex in midbrain raphe 5-HT neuron systems via allosteric receptor-receptor interaction.

artículo científico publicado en 2015

Increased density and antagonistic allosteric interactions in A2AR-D2R heterocomplexes in extinction from cocaine use, lost in cue induced reinstatement of cocaine seeking

scientific article published in 2022

Information handling by the brain: proposal of a new "paradigm" involving the roamer type of volume transmission and the tunneling nanotube type of wiring transmission

artículo científico

Integrin triplets of marine sponges in human D2 receptor heteromers

artículo científico publicado en 2012

Integrin triplets of marine sponges in human brain receptor heteromers.

artículo científico publicado en 2012

Mapping the Interface of a GPCR Dimer: A Structural Model of the A2A Adenosine and D2 Dopamine Receptor Heteromer.

artículo científico publicado en 2018

Microvesicle and tunneling nanotube mediated intercellular transfer of g-protein coupled receptors in cell cultures.

artículo científico publicado en 2012

Molecular determinants of A2AR-D2R allosterism: role of the intracellular loop 3 of the D2R.

artículo científico publicado en 2012

Moonlighting characteristics of G protein-coupled receptors: focus on receptor heteromers and relevance for neurodegeneration.

artículo científico publicado en 2011

Moonlighting proteins and protein-protein interactions as neurotherapeutic targets in the G protein-coupled receptor field

artículo científico

Multiple Adenosine-Dopamine (A2A-D2 Like) Heteroreceptor Complexes in the Brain and Their Role in Schizophrenia

artículo científico publicado en 2020

Multiple D2 heteroreceptor complexes: new targets for treatment of schizophrenia

artículo científico publicado en 2016

Muscarinic acetylcholine receptor-interacting proteins (mAChRIPs): targeting the receptorsome.

artículo científico publicado en 2012

Muscarinic receptor family interacting proteins: role in receptor function.

artículo científico publicado en 2010

Neurotensin NTS1-dopamine D2 receptor-receptor interactions in putative receptor heteromers: relevance for Parkinson's disease and schizophrenia.

artículo científico

OSU-6162, a Sigma1R Ligand in Low Doses, Can Further Increase the Effects of Cocaine Self-Administration on Accumbal D2R Heteroreceptor Complexes

scientific article published on 28 November 2019

On the G Protein-Coupled Receptor Neuromodulation of the Claustrum

scientific article published on 06 June 2019

On the existence and function of galanin receptor heteromers in the central nervous system

artículo científico publicado en 2012

On the existence of a possible A2A-D2-β-Arrestin2 complex: A2A agonist modulation of D2 agonist-induced β-arrestin2 recruitment.

artículo científico publicado en 2011

On the g-protein-coupled receptor heteromers and their allosteric receptor-receptor interactions in the central nervous system: focus on their role in pain modulation

artículo científico publicado en 2013

On the origin of the triplet puzzle of homologies in receptor heteromers: Toll-like receptor triplets in different types of receptors

artículo científico publicado en 2011

On the origin of the triplet puzzle of homologies in receptor heteromers: immunoglobulin triplets in different types of receptors

artículo científico publicado en 2011

On the role of A₂A and D₂ receptors in control of cocaine and food-seeking behaviors in rats

artículo científico publicado en 2014

On the role of volume transmission and receptor-receptor interactions in social behaviour: focus on central catecholamine and oxytocin neurons

artículo científico publicado en 2012

Overproduction of human M₃ muscarinic acetylcholine receptor: an approach toward structural studies

artículo científico publicado en 2011

Possible genetic and epigenetic links between human inner speech, schizophrenia and altruism.

artículo científico

Potential of caveolae in the therapy of cardiovascular and neurological diseases

artículo científico publicado en 2014

Preferential activation by galanin 1-15 fragment of the GalR1 protomer of a GalR1-GalR2 heteroreceptor complex.

artículo científico publicado en 2014

Purinergic signaling in Parkinson's disease. Relevance for treatment

artículo científico

Receptor⁻Receptor Interactions in Multiple 5-HT1A Heteroreceptor Complexes in Raphe-Hippocampal 5-HT Transmission and Their Relevance for Depression and Its Treatment.

artículo científico publicado en 2018

Role of dimerization in dopamine D(4) receptor biogenesis

artículo científico

Role of iso-receptors in receptor-receptor interactions with a focus on dopamine iso-receptor complexes.

artículo científico

Signaling in dopamine D2 receptor-oxytocin receptor heterocomplexes and its relevance for the anxiolytic effects of dopamine and oxytocin interactions in the amygdala of the rat.

artículo científico publicado en 2016

Speaker 4: Dasiel Borroto – Escuela, Sweden

artículo científico publicado en 2016

The G protein-coupled receptor heterodimer network (GPCR-HetNet) and its hub components

artículo científico publicado en 2014

The changing world of G protein-coupled receptors: from monomers to dimers and receptor mosaics with allosteric receptor-receptor interactions

artículo científico publicado en 2010

The existence of FGFR1-5-HT1A receptor heterocomplexes in midbrain 5-HT neurons of the rat: relevance for neuroplasticity

scientific journal article

The impact of receptor-receptor interactions in heteroreceptor complexes on brain plasticity.

artículo científico publicado en 2014

The role of transmitter diffusion and flow versus extracellular vesicles in volume transmission in the brain neural-glial networks

artículo científico publicado en 2015

The zinc binding receptor GPR39 interacts with 5-HT1A and GalR1 to form dynamic heteroreceptor complexes with signaling diversity

artículo científico publicado en 2015

Understanding the Functional Plasticity in Neural Networks of the Basal Ganglia in Cocaine Use Disorder: A Role for Allosteric Receptor-Receptor Interactions in A2A-D2 Heteroreceptor Complexes

artículo científico publicado en 2016

Understanding the Role of Adenosine A2AR Heteroreceptor Complexes in Neurodegeneration and Neuroinflammation

artículo científico publicado en 2018

Understanding the Role of GPCR Heteroreceptor Complexes in Modulating the Brain Networks in Health and Disease

artículo científico publicado en 2017

Understanding the balance and integration of volume and synaptic transmission. Relevance for psychiatry

article

Understanding the role of heteroreceptor complexes in the central nervous system

artículo científico publicado en 2014

Vectors and P64k gene targeting for tandem affinity purification in Neisseria meningitidis.

artículo científico publicado en 2005

Volume Transmission in Central Dopamine and Noradrenaline Neurons and Its Astroglial Targets.

artículo científico

Volume transmission and its different forms in the central nervous system

artículo científico publicado en 2013

Volume transmission and receptor-receptor interactions in heteroreceptor complexes: understanding the role of new concepts for brain communication

artículo científico publicado en 2016

Differential activation of arginine-vasopressin receptor subtypes in the amygdaloid modulation of anxiety in the rat by arginine-vasopressin

artículo científico publicado en 2018

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