Lista de obras - Christopher Langendorf - Dominio Público Uruguay

1,2,6-Thiadiazinones as Novel Narrow Spectrum Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CaMKK2) Inhibitors

artículo científico publicado en 2018

AMP-activated protein kinase selectively inhibited by the type II inhibitor SBI-0206965.

artículo científico publicado en 2018

ATP sensitive bi-quinoline activator of the AMP-activated protein kinase.

artículo científico publicado en 2013

An Analysis of the Cross-Reactivity of Autoantibodies to GAD65 and GAD67 in Diabetes ⬇️

artículo científico publicado el 8 de abril de 2011

Autophosphorylation of CaMKK2 generates autonomous activity that is disrupted by a T85S mutation linked to anxiety and bipolar disorder

artículo científico publicado en 2015

CaMKK2 is inactivated by cAMP-PKA signaling and 14-3-3 adaptor proteins

scientific article published on 09 September 2020

Choreography of AMPK activation.

artículo científico publicado en 2014

Conformational change in the chromatin remodelling protein MENT

artículo científico publicado en 2009

Fake Inhibitors: AMPK Activation Trumps Inhibition

artículo científico publicado en 2017

Functional analysis of an R311C variant of Ca2+ -calmodulin-dependent protein kinase kinase-2 (CaMKK2) found as a de novo mutation in a patient with bipolar disorder

scientific article published on 25 March 2020

GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop

artículo científico publicado en 2007

In Depth Analysis of Kinase Cross Screening Data to Identify CAMKK2 Inhibitory Scaffolds

artículo científico publicado en 2020

Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release.

artículo científico publicado en 2015

Protein kinase A negatively regulates VEGF-induced AMPK activation by phosphorylating CaMKK2 at serine 495

scientific article published on 01 September 2020

Small molecule drug A-769662 and AMP synergistically activate naive AMPK independent of upstream kinase signaling.

artículo científico publicado en 2014

Structural Determinants for Small-Molecule Activation of Skeletal Muscle AMPK α2β2γ1 by the Glucose Importagog SC4.

artículo científico publicado en 2018

Structural basis of allosteric and synergistic activation of AMPK by furan-2-phosphonic derivative C2 binding

artículo científico publicado en 2016

Structural characterization of the mechanism through which human glutamic acid decarboxylase auto-activates

artículo científico publicado en 2013

Structural mechanisms of inactivation in scabies mite serine protease paralogues

artículo científico publicado en 2009

The X-Ray Crystal Structure of Escherichia coli Succinic Semialdehyde Dehydrogenase; Structural Insights into NADP+/Enzyme Interactions

artículo científico publicado en 2010

The autophagy initiator ULK1 sensitizes AMPK to allosteric drugs

artículo científico publicado en 2017

Visualizing AMPK Drug Binding Sites Through Crystallization of Full-Length Phosphorylated α2β1γ1 Heterotrimer

artículo científico publicado en 2018

X-ray crystal structure of the fibrinolysis inhibitor alpha2-antiplasmin

artículo científico publicado en 2008

mTORC1 directly inhibits AMPK to promote cell proliferation under nutrient stress

scientific article published on 20 January 2020

Lista de obras de Christopher Langendorf

1,2,6-Thiadiazinones as Novel Narrow Spectrum Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CaMKK2) Inhibitors

AMP-activated protein kinase selectively inhibited by the type II inhibitor SBI-0206965.

ATP sensitive bi-quinoline activator of the AMP-activated protein kinase.

An Analysis of the Cross-Reactivity of Autoantibodies to GAD65 and GAD67 in Diabetes ⬇️

Autophosphorylation of CaMKK2 generates autonomous activity that is disrupted by a T85S mutation linked to anxiety and bipolar disorder

CaMKK2 is inactivated by cAMP-PKA signaling and 14-3-3 adaptor proteins

Choreography of AMPK activation.

Conformational change in the chromatin remodelling protein MENT

Fake Inhibitors: AMPK Activation Trumps Inhibition

Functional analysis of an R311C variant of Ca2+ -calmodulin-dependent protein kinase kinase-2 (CaMKK2) found as a de novo mutation in a patient with bipolar disorder

GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop

In Depth Analysis of Kinase Cross Screening Data to Identify CAMKK2 Inhibitory Scaffolds

Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release.

Protein kinase A negatively regulates VEGF-induced AMPK activation by phosphorylating CaMKK2 at serine 495

Small molecule drug A-769662 and AMP synergistically activate naive AMPK independent of upstream kinase signaling.

Structural Determinants for Small-Molecule Activation of Skeletal Muscle AMPK α2β2γ1 by the Glucose Importagog SC4.

Structural basis of allosteric and synergistic activation of AMPK by furan-2-phosphonic derivative C2 binding

Structural characterization of the mechanism through which human glutamic acid decarboxylase auto-activates

Structural mechanisms of inactivation in scabies mite serine protease paralogues

The X-Ray Crystal Structure of Escherichia coli Succinic Semialdehyde Dehydrogenase; Structural Insights into NADP+/Enzyme Interactions

The autophagy initiator ULK1 sensitizes AMPK to allosteric drugs

Visualizing AMPK Drug Binding Sites Through Crystallization of Full-Length Phosphorylated α2β1γ1 Heterotrimer

X-ray crystal structure of the fibrinolysis inhibitor alpha2-antiplasmin

mTORC1 directly inhibits AMPK to promote cell proliferation under nutrient stress