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Lista de obras de Herman Waldmann

"Infectious" transplantation tolerance.

artículo científico publicado en 1993

(5) Induction of remission in systemic vasculitis with monoclonal antibody Campath-1H

1.9 A structure of the therapeutic antibody CAMPATH-1H fab in complex with a synthetic peptide antigen

artículo científico publicado en 1999

1.9 Å structure of the therapeutic antibody CAMPATH-1H fab in complex with a synthetic peptide antigen

A Bacterial Artificial Chromosome Reporter System for Expression of the Human FOXP3 Gene in Mouse Regulatory T-Cells

artículo científico publicado en 2017

A Novel Role for Triglyceride Metabolism in Foxp3 Expression

scientific article published on 13 August 2019

A Novel Strategy To Reduce the Immunogenicity of Biological Therapies

article

A humanised therapeutic CD4 mAb inhibits TCR-induced IL-2, IL-4, and IL-10 secretion and expression of CD25, CD40L, and CD69.

artículo científico publicado en 1998

A humanized CD18 antibody can block function without cell destruction

artículo científico publicado en 1993

A humanized monovalent CD3 antibody which can activate homologous complement

artículo científico publicado en 1991

A key role for TGF-beta signaling to T cells in the long-term acceptance of allografts

artículo científico publicado en 2007

A matched set of rat/mouse chimeric antibodies. Identification and biological properties of rat H chain constant regions mu, gamma 1, gamma 2a, gamma 2b, gamma 2c, epsilon, and alpha

artículo científico publicado en 1989

A noncomitogenic CD2R monoclonal antibody induces apoptosis of activated T cells by a CD95/CD95-L-dependent pathway ⬇️

artículo científico publicado el 1 de mayo de 1998

A novel role for Glucocorticoid-Induced TNF Receptor Ligand (Gitrl) in early embryonic zebrafish development

artículo científico publicado en 2010

A personal history of the CAMPATH-1H antibody

artículo científico

A pilot study of combination anti-cytokine and anti-lymphocyte biological therapy in rheumatoid arthritis.

artículo científico publicado en 2008

A rapid solid-phase enzyme-linked binding assay for screening monoclonal antibodies to cell surface antigens

scientific article published on 01 January 1981

A repertoire of monoclonal antibodies with human heavy chains from transgenic mice

artículo científico publicado en 1989

A role for CD4+ but not CD8+ T cells in immunity to Schistosoma mansoni induced by 20 krad-irradiated and Ro 11-3128-terminated infections

artículo científico publicado en 1989

A role for Th2 cytokines in the suppression of CD8+ T cell-mediated graft rejection

artículo científico publicado en 1997

A role for regulatory T cells in acceptance of ESC-derived tissues transplanted across an major histocompatibility complex barrier

artículo científico publicado en 2010

A theoretical framework for self-tolerance and its relevance to therapy of autoimmune disease

article published in 1988

A therapeutic human IgG4 monoclonal antibody that depletes target cells in humans

artículo científico publicado en 1996

AMPLIFICATION OF NATURAL REGULATORY IMMUNE MECHANISMS FOR TRANSPLANTATION TOLERANCE1

scientific article published on 01 November 1996

Accelerated memory cell homeostasis during T cell depletion and approaches to overcome it.

artículo científico publicado en 2006

Activated regulatory T cells are the major T cell type emigrating from the skin during a cutaneous immune response in mice

artículo científico publicado en 2010

Activation rather than Foxp3 expression determines that TGF-β-induced regulatory T cells out-compete naïve T cells in dendritic cell clustering

artículo científico publicado en 2012

Active suppression induced by anti-CD4

artículo científico publicado en 1993

Adoptive Suppression of Erythrocyte Autoantibodies in Lyt-2+Depleted Recipients

scientific article published on 01 January 1989

Advantages of rat monoclonal antibodies

artículo científico publicado en 1983

Alemtuzumab (CAMPATH 1H) induction therapy in cadaveric kidney transplantation--efficacy and safety at five years.

artículo científico publicado en 2005

Alemtuzumab (CAMPATH-1H) for the treatment of acute rejection in kidney transplant recipients: long-term follow-up.

artículo científico publicado en 2009

Alemtuzumab (Campath-1H) for treatment of lymphoid malignancies in the age of nonmyeloablative conditioning?

artículo científico publicado en 2002

Alemtuzumab (Campath-1H) in allogeneic stem cell transplantation: where do we go from here?

artículo científico publicado en 2004

Allosuppression: evidence for the involvement of both “noncytotoxic” and cytotoxic T cells ⬇️

artículo científico publicado el 1 de julio de 1984

Alopecia areata: Animal models illuminate autoimmune pathogenesis and novel immunotherapeutic strategies

artículo científico publicado en 2016

Anti-CD3 treatment up-regulates programmed cell death protein-1 expression on activated effector T cells and severely impairs their inflammatory capacity

artículo científico publicado en 2017

Anti-CD45 monoclonal antibody YAML568: A promising radioimmunoconjugate for targeted therapy of acute leukemia.

artículo científico publicado en 2006

Anti-adhesion Molecule Therapy as an Interventional Strategy

artículo científico publicado en 1999

Anti-globulin responses to rat and humanized CAMPATH-1 monoclonal antibody used to treat transplant rejection

artículo científico publicado en 1999

Antibody-induced transplantation tolerance: the role of dominant regulation

artículo científico publicado en 2003

Antilymphocytic antibodies and marrow transplantation. VII. Two of nine monoclonal anti-Thy-1 antibodies used for pretreatment of donor marrow suppressed graft-versus-host reactions without added complement

artículo científico publicado en 1985

Apoptosis: potential for disease therapies

artículo científico publicado en 1998

Approaching Tolerance in Transplantation ⬇️

artículo científico publicado el 1 de septiembre de 2001

Appropriate targets for monoclonal antibodies in the induction of transplantation tolerance

artículo científico publicado en 2001

Autoimmune diabetes onset results from qualitative rather than quantitative age-dependent changes in pathogenic T-cells

artículo científico publicado en 2005

Autologous Transplantation with CD52 Monoclonal Antibody-Purged Marrow for Acute Lymphoblastic Leukemia: Long-Term Follow-Up

artículo científico publicado en 1997

Availability of Campath-1 antibodies for bone marrow transplantation

artículo científico publicado en 1995

B cell activation

artículo científico publicado en 1975

Beneficial effect of monoclonal antibody to interleukin 2 receptor on activated T cells in rheumatoid arthritis

artículo científico publicado en 1989

Biomarkers of transplantation tolerance: more hopeful than helpful?

artículo científico publicado en 2011

Blocking of cytotoxic T cell function by monoclonal antibodies against the CD45 antigen (T200/leukocyte-common antigen)

scientific article published on 01 December 1987

Blood concentrations of alemtuzumab and antiglobulin responses in patients with chronic lymphocytic leukemia following intravenous or subcutaneous routes of administration

artículo científico publicado en 2004

Bone Marrow Transplantation for Patients with Chronic Myeloid Leukemia

article

Bone marrow transplantation for chronic myeloid leukemia with volunteer unrelated donors using ex vivo or in vivo T-cell depletion: major prognostic impact of HLA class I identity between donor and recipient

artículo científico publicado en 1995

Bone marrow transplantation for patients with chronic myeloid leukaemia: T-cell depletion with Campath-1 reduces the incidence of graft-versus-host disease but may increase the risk of leukaemic relapse

artículo científico publicado en 1986

Bone marrow transplantation in beta-thalassemia major with prevention of graft-vs-host disease

artículo científico publicado en 1988

Bone marrow transplantation induces either clonal deletion or infectious tolerance depending on the dose ⬇️

artículo científico publicado el 15 de marzo de 1998

Both CD4(+)CD25(+) and CD4(+)CD25(-) regulatory cells mediate dominant transplantation tolerance

CAMPATH IH ALLOWS LOW-DOSE CYCLOSPORINE MONOTHERAPY IN 31 CADAVERIC RENAL ALLOGRAFT RECIPIENTS

artículo científico publicado en 1999

CAMPATH-1 antibodies in stem-cell transplantation

artículo científico publicado en 2001

CAMPATH-1 monoclonal antibodies in bone marrow transplantation.

artículo científico publicado en 1994

CAMPATH-1 monoclonal antibody therapy in severe refractory autoimmune thrombocytopenic purpura

artículo científico publicado en 1993

CAMPATH-1H in inflammatory arthritis

artículo científico publicado en 1993

CAMPATH-1H in multiple sclerosis

artículo científico publicado en 1996

CAMPATH: from concept to clinic

artículo científico publicado en 2005

CD 4 and CD 8 monoclonal antibody therapy in canine renal allografts

scientific article published on 01 January 1994

CD3 monoclonal antibodies: a first step towards operational immune tolerance in the clinic

artículo científico

CD4 T cells can reject major histocompatibility complex class I-incompatible skin grafts

artículo científico publicado en 1999

CD4 and CD8 monoclonal antibody therapy: Strategies to prolong renal allograft survival in the dog

artículo científico publicado en 1993

CD4 mAbs PREVENT PROGRESSION OF ALLOACTIVATED CD4+ T CELLS INTO THE S PHASE OF THE CELL CYCLE WITHOUT INTERFERING WITH EARLY ACTIVATION SIGNALS1

artículo científico publicado en 1996

CD4 monoclonal antibodies in the preclinical dog renal allograft model

scientific article published on 01 February 1993

CD4 monoclonal antibody pairs for immunosuppression and tolerance induction

artículo científico publicado en 1987

CD4+ T Cell Fate Decisions Are Stochastic, Precede Cell Division, Depend on GITR Co-Stimulation, and Are Associated With Uropodium Development

artículo científico publicado en 2018

CD40 ligand blockade induces CD4+ T cell tolerance and linked suppression

scientific article published on 01 November 1999

CD52 antibodies for prevention of graft-versus-host disease and graft rejection following transplantation of allogeneic peripheral blood stem cells

artículo científico publicado en 2000

CD52-Negative NK Cells Are Abundant in the Liver and Less Susceptible to Alemtuzumab Treatment

artículo científico publicado en 2016

CD59, an LY-6-like protein expressed in human lymphoid cells, regulates the action of the complement membrane attack complex on homologous cells

artículo científico publicado en 1989

CD66 identifies a neutrophil-specific epitope within the hematopoietic system that is expressed by members of the carcinoembryonic antigen family of adhesion molecules ⬇️

artículo científico publicado el 1 de julio de 1991

CD73 and adenosine generation in the creation of regulatory microenvironments ⬇️

artículo científico publicado el 1 de enero de 2013

CD8+ T-Cell depletion and rapamycin synergize with combined coreceptor/stimulation blockade to induce robust limb allograft tolerance in mice

artículo científico publicado en 2008

CD8+ lymphocytes do not mediate protection against acute superinfection 20 days after vaccination with a live attenuated simian immunodeficiency virus

artículo científico publicado en 2005

Campath-1 Abs 'in the bag' for hematological malignancies: the Cape Town experience

artículo científico publicado en 2004

Campath-1G in vivo confers a low incidence of graft-versus-host disease associated with a high incidence of mixed chimaerism after bone marrow transplantation for severe aplastic anaemia using HLA-identical sibling donors

artículo científico publicado en 1996

Campath-1H therapy in refractory ocular inflammatory disease

artículo científico publicado en 2000

Campath-1M--prophylactic use after kidney transplantation. A randomized controlled clinical trial

scientific article published on 01 August 1989

Cell replacement therapy and the evasion of destructive immunity

artículo científico publicado en 2005

Cell- and tissue-specific expression of a human CD59 minigene in transgenic mice

artículo científico publicado en 1994

Cell-surface markers on haemopoietic precursors. Reagents for the isolation and analysis of progenitor cell subpopulations.

artículo científico publicado en 1987

Characterization of effector cells of graft vs leukemia following allogeneic bone marrow transplantation in mice inoculated with murine B-cell leukemia

artículo científico publicado en 1990

Characterization of the CAMPATH-1 (CDw52) antigen: biochemical analysis and cDNA cloning reveal an unusually small peptide backbone

artículo científico publicado en 1991

Children with acute lymphoblastic leukemia who receive T-cell-depleted HLA mismatched marrow allografts from unrelated donors have an increased incidence of primary graft failure but a similar overall transplant outcome.

artículo científico publicado en 1999

Classical transplantation tolerance in the adult: the interaction between myeloablation and immunosuppression.

artículo científico publicado en 1992

Clinical evidence of a graft-versus-Hodgkin's-lymphoma effect after reduced-intensity allogeneic transplantation

artículo científico publicado en 2005

Co-receptor and co-stimulation blockade for mixed chimerism and tolerance without myelosuppressive conditioning

artículo científico publicado en 2006

Combined use of RS61443 with CD4 and CD8 MAbs to generate tolerance to skin xenografts from rat to mouse

artículo científico publicado en 1994

Comparison of allogeneic T cell-depleted peripheral blood stem cell and bone marrow transplantation: effect of stem cell source on short- and long-term outcome

scientific article published on 01 May 2001

Comparison of the effector functions of human immunoglobulins using a matched set of chimeric antibodies.

artículo científico publicado en 1987

Complement activation by immunoglobulin does not depend solely on C1q binding

artículo científico publicado en 1990

Connecting the mechanisms of T-cell regulation: dendritic cells as the missing link

scientific article published on July 2010

Control of graft-versus-host disease and graft rejection by T cell depletion of donor and recipient with Campath-1 antibodies. Results of matched sibling transplants for malignant diseases.

artículo científico publicado en 1994

Control of immune-mediated disease of the central nervous system with monoclonal (CD4-specific) antibodies

artículo científico publicado en 1993

Cooperation across the histocompatibility barrier

artículo científico publicado en 1975

Cooperation across the histocompatibility barrier: H2d T cells primed to antigen in an H-2d environment can cooperate with H-2k B cells

artículo científico publicado en 1976

Coreceptor blockade targeting CD4 and CD8 allows acceptance of allogeneic human pluripotent stem cell grafts in humanized mice

scientific article published on 02 April 2020

Correction: Resistance of regulatory T cells to glucocorticoid-induced TNFR family-related protein (GITR) duringPlasmodium yoelii infection

Correction: Secreted and Transmembrane 1A Is a Novel Co-Stimulatory Ligand

Corrigendum: Therapeutic potential of monovalent monoclonal antibodies

artículo científico publicado en 1984

Critical Influence of Natural Regulatory CD25+ T Cells on the Fate of Allografts in the Absence of Immunosuppression

artículo científico publicado en 2005

Crystal structures of a rat anti-CD52 (CAMPATH-1) therapeutic antibody Fab fragment and its humanized counterpart

artículo científico publicado en 1998

Cutting Edge: Anti-CD154 Therapeutic Antibodies Induce Infectious Transplantation Tolerance

scientific article published on 01 November 2000

DELAYED ALLOGRAFT REJECTION IN PRIMATES TREATED WITH ANTI-IL-2 RECEPTOR MONOCLONAL ANTIBODY CAMPATH-6

artículo científico publicado en 1988

DOMINANT TOLERANCE AND LINKED SUPPRESSION INDUCED BY THERAPEUTIC ANTIBODIES DO NOT DEPEND ON FAS-FASL INTERACTIONS1

scientific article published on 01 April 2000

Delay in onset of insulitis in NOD mice following a single injection of CD 4 and CD8 antibodies

artículo científico publicado en 1988

Depletion of CD4+ and CD8+ cells eliminates immunologic memory of thyroiditogenicity in murine experimental autoimmune thyroiditis.

artículo científico publicado en 1994

Depletion of L3T4+ and Lyt-2+ cells by rat monoclonal antibodies alters the development of adoptively transferred experimental autoimmune thyroiditis

article

Detection of monoclonal antibodies against cell surface antigens: the use of antiglobulins coupled to red blood cells

artículo científico publicado en 1984

Development and clinical use of CAMPATH® 1H

article

Dickkopf-3, a tissue-derived modulator of local T-cell responses

artículo científico publicado en 2015

Different roles for L3T4+ and Lyt 2+ T cell subsets in the control of an acute herpes simplex virus infection of the skin and nervous system

artículo científico publicado en 1987

Direct antibody rosette-forming reactions using monoclonal markers of lymphocyte subpopulations. Methodology and applications illustrated by investigations with rat pan-T antibodies of the CAMPATH series.

artículo científico publicado en 1986

Directed differentiation of dendritic cells from mouse embryonic stem cells.

artículo científico publicado en 2000

Do L3T4+ T cells act as effector cells in protection against influenza virus infection

artículo científico publicado en 1987

Dominant tolerance: activation thresholds for peripheral generation of regulatory T cells

artículo científico publicado en 2005

Dominant transplantation tolerance impairs CD8+ T cell function but not expansion

artículo científico publicado en 2002

Dominant transplantation tolerance. Opinion

artículo científico publicado en 2003

Donor-specific transplantation tolerance: the paradoxical behavior of CD4+CD25+ T cells

artículo científico publicado en 2004

Double T cell depletion of bone marrow using sequential positive and negative cell immunoaffinity or CD34+ cell selection followed by Campath-1M; effect on CD34+ cells and progenitor cell recoveries

artículo científico publicado en 1998

Drug minimization in transplantation

artículo científico publicado en 2014

EFFECT OF GRAFT PERFUSION WITH TWO CD45 MONOCLONAL ANTIBODIES ON INCIDENCE OF KIDNEY ALLOGRAFT REJECTION

scientific article published in The Lancet

EX VIVO DEPLETION OF T CELLS FROM BONE MARROW GRAFTS WITH CAMPATH-1 IN ACUTE LEUKEMIA

article published in 1999

Ectopic Transplantation of Tissues Under the Kidney Capsule

Ectopic transplantation of tissues under the kidney capsule

scientific article published on 01 January 2007

Effect of CD4 monoclonal antibody in vivo on lesion development, delayed-type hypersensitivity and interleukin 3 production in experimental murine cutaneous leishmaniasis

scientific article published on 01 March 1989

Effects of CAMPATH-1 antibodies in vivo in patients with lymphoid malignancies: influence of antibody isotype

scientific article published on 01 May 1989

Effects of monoclonal anti-lymphocyte antibodies in vivo in monkeys and humans

artículo científico publicado en 1983

Efficient complement-mediated lysis of cells containing the CAMPATH-1 (CDw52) antigen

artículo científico publicado en 1993

Elimination of graft-versus-host disease by in-vitro depletion of alloreactive lymphocytes with a monoclonal rat anti-human lymphocyte antibody (CAMPATH-1).

artículo científico publicado en 1984

Elimination of the immunogenicity of therapeutic antibodies

artículo científico publicado en 1999

Embryonic stem cell-derived tissues are immunogenic but their inherent immune privilege promotes the induction of tolerance

artículo científico publicado en 2007

Embryonic stem cells and the challenge of transplantation tolerance

artículo científico publicado en 2004

Embryonic stem cells: a novel source of dendritic cells for clinical applications.

artículo científico publicado en 2005

Embryonic stem cells: overcoming the immunological barriers to cell replacement therapy

artículo científico publicado en 2009

Embryonic stem cells: protecting pluripotency from alloreactivity

artículo científico publicado en 2007

Engraftment of marrow allografts treated with Campath-1 monoclonal antibodies

scientific article published on 01 July 1999

Enhanced efficacy from gene therapy in Pompe disease using coreceptor blockade

artículo científico publicado en 2015

Enhanced murine contact hypersensitivity by depletion of endogenous regulatory T cells in the sensitization phase

artículo científico publicado en 2010

Enhanced production of IL-10 by dendritic cells deficient in CIITA.

artículo científico publicado en 2005

Enhancement of humoral and cellular immunity with an anti-glucocorticoid-induced tumour necrosis factor receptor monoclonal antibody

artículo científico publicado en 2010

Epstein-Barr virus (EBV) associated B-cell lymphoproliferative disease following HLA identical sibling marrow transplantation for aplastic anaemia in a patient with an EBV seronegative donor

artículo científico publicado en 1999

Evidence for the inactivation of precursor B cells in high dose unresponsiveness

artículo científico publicado en 1976

Ex vivo T-cell depletion with the monoclonal antibody Campath-1 plus human complement effectively prevents acute graft-versus-host disease in allogeneic bone marrow transplantation

scientific article published on 01 November 1986

Ex vivo depletion of T cells from bone marrow grafts with CAMPATH-1 in acute leukemia: graft-versus-host disease and graft-versus-leukemia effect

Ex-vivo whole blood cultures for predicting cytokine-release syndrome: dependence on target antigen and antibody isotype

scientific article published on 01 August 1995

Exacerbation of delayed-type hypersensitivity responses in EBV-induced gene-3 (EBI-3)-deficient mice

artículo científico publicado en 2010

Excessive T cell depletion of peripheral blood stem cells has an adverse effect upon outcome following allogeneic stem cell transplantation

artículo científico publicado en 2001

Expansion of Foxp3(+) T-cell populations by Candida albicans enhances both Th17-cell responses and fungal dissemination after intravenous challenge.

artículo científico publicado en 2014

Exploiting tolerance processes in transplantation

artículo científico publicado en 2004

Expression of human GITRL on myeloid dendritic cells enhances their immunostimulatory function but does not abrogate the suppressive effect of CD4+CD25+ regulatory T cells

artículo científico publicado en 2007

Expression of murine IL-12 is regulated by translational control of the p35 subunit

artículo científico publicado en 1999

Extrathymic signals regulate the onset of T cell repertoire selection

scientific article published on 01 July 2000

Fas-independent apoptosis of activated T cells induced by antibodies to the HLA class I alpha1 domain

artículo científico publicado en 1997

Favorable effect on acute and chronic graft-versus-host disease with cyclophosphamide and in vivo anti-CD52 monoclonal antibodies for marrow transplantation from HLA-identical sibling donors for acquired aplastic anemia

artículo científico publicado en 2004

Fc-disabled anti-mouse CD40L antibodies retain efficacy in promoting transplantation tolerance

artículo científico publicado en 2008

Four-year metabolic outcome of a randomised controlled CD3-antibody trial in recent-onset type 1 diabetic patients depends on their age and baseline residual beta cell mass

artículo científico publicado en 2010

Foxp3 T reg cells control psoriasiform inflammation by restraining an IFN-I-driven CD8 T cell response

artículo científico publicado en 2018

Foxp3 drives oxidative phosphorylation and protection from lipotoxicity.

artículo científico publicado en 2017

Foxp3 expression is required for the induction of therapeutic tissue tolerance

artículo científico publicado en 2012

From Laboratory to Clinic : The Story of CAM PA TH-1

artículo científico publicado en 2000

Functional analysis of T lymphocyte subsets in antiviral host defense.

artículo científico publicado en 1987

Gene expression in the Gitr locus is regulated by NF-κB and Foxp3 through an enhancer

artículo científico publicado en 2014

Gene structure of human CD59 and demonstration that discrete mRNAs are generated by alternative polyadenylation

artículo científico publicado en 1992

Generation of anergic and regulatory T cells following prolonged exposure to a harmless antigen

artículo científico publicado en 2004

Generation of anti-inflammatory adenosine byleukocytes is regulated by TGF-β

scientific article published on 06 September 2011

Generation of immunogenic dendritic cells from human embryonic stem cells without serum and feeder cells

artículo científico publicado en 2009

Genetic Modification of Dendritic Cells Through the Directed Differentiation of Embryonic Stem Cells

Genetic modification of dendritic cells through the directed differentiation of embryonic stem cells

artículo científico publicado en 2007

Guiding Postablative Lymphocyte Reconstitution as a Route Toward Transplantation Tolerance

artículo científico publicado en 2014

HIGH DOSE BONE MARROW TRANSPLANTATION INDUCES DELETION OF ANTIGEN-SPECIFIC T CELLS IN A FAS-INDEPENDENT MANNER1

scientific article published on 01 April 2000

Haemopoietic progenitor cell heterogeneity revealed by a single monoclonal antibody, YW 13.1.1.

artículo científico publicado en 1984

Harnessing FOXP3+ regulatory T cells for transplantation tolerance.

artículo científico publicado en 2014

Heterogeneity of natural Foxp3+ T cells: a committed regulatory T-cell lineage and an uncommitted minor population retaining plasticity

scholarly article

High incidence of cytomegalovirus infection after nonmyeloablative stem cell transplantation: potential role of Campath-1H in delaying immune reconstitution

scientific article published on 01 June 2002

High level transcription of the complement regulatory protein CD59 requires an enhancer located in intron 1.

artículo científico publicado en 1999

How do monoclonal antibodies induce tolerance? A role for infectious tolerance?

How many T cells help one B cell?

artículo científico publicado en 1980

Human CD3 Transgenic Mice: Preclinical Testing of Antibodies Promoting Immune Tolerance

scientific article published on 01 February 2011

Human CD59 expressed in transgenic mouse hearts inhibits the activation of complement

artículo científico publicado en 1995

Human Monoclonal Antibodies: The Benefits of Humanization

artículo científico publicado en 2019

Human Monoclonal Antibodies: The Residual Challenge of Antibody Immunogenicity ⬇️

artículo científico publicado el 1 de enero de 2014

Human monoclonal IgG isotypes differ in complement activating function at the level of C4 as well as C1q.

artículo científico publicado en 1988

Human protectin (CD59), an 18,000-20,000 MW complement lysis restricting factor, inhibits C5b-8 catalysed insertion of C9 into lipid bilayers ⬇️

artículo científico publicado el 1 de septiembre de 1990

Humanised monoclonal antibody therapy for rheumatoid arthritis

artículo científico publicado en 1992

Humanized anti-CD4 monoclonal antibody therapy of autoimmune and inflammatory disease

artículo científico publicado en 1997

Humanized monoclonal antibody treatment in rheumatoid arthritis

artículo científico publicado en 1991

Hybrid antibodies for therapy

artículo científico publicado en 1988

IL-10 gene expression is controlled by the transcription factors Sp1 and Sp3.

artículo científico publicado en 2000

IL-10-conditioned dendritic cells, decommissioned for recruitment of adaptive immunity, elicit innate inflammatory gene products in response to danger signals

scientific journal article

IMMUNE RECONSTITUTION AFTER ALLOGENEIC BONE MARROW TRANSPLANTATION DEPLETED OF T CELLS

artículo científico publicado en 2000

Identification of cells of the human mononuclear phagocyte system with rat monoclonal antibodies

scientific article published on 01 August 1987

Identification of macrophages and smooth muscle cells in human atherosclerosis using monoclonal antibodies

scientific article published on 01 July 1985

Identification of regulatory T cells in tolerated allografts

artículo científico publicado en 2002

Immune privilege induced by regulatory T cells in transplantation tolerance

artículo científico publicado en 2006

Immune reconstitution at 6 months following T-cell depleted hematopoietic stem cell transplantation is predictive for treatment outcome

artículo científico publicado en 2002

Immunoglobulin heavy chain locus of the rat: striking homology to mouse antibody genes

artículo científico publicado en 1986

Immunohistological screening in the selection of monoclonal antibodies: the use of isotype-specific antiglobulins

artículo científico publicado en 1984

Immunological tolerance

scholarly article by Harald von Boehmer & Herman Waldmann published 2010 in Frontiers in Immunology

Immunosuppression of canine renal allograft recipients by CD4 and CD8 monoclonal antibodies

artículo científico publicado en 1994

Immunosuppression with monoclonal antibodies. A model to determine the rules for effective serotherapy

scientific article published on 01 October 1983

Impact on T-cell depletion and CD34+ cell recovery using humanised CD52 monoclonal antibody (CAMPATH-1H) in BM and PSBC collections; comparison with CAMPATH-1M and CAMPATH-1G

artículo científico publicado en 2000

Importance of antigen specificity for complement-mediated lysis by monoclonal antibodies.

artículo científico publicado en 1988

Improving the outcome of bone marrow transplantation by using CD52 monoclonal antibodies to prevent graft-versus-host disease and graft rejection

artículo científico publicado en 1998

In vitro and in vivo depletion of T cells.

artículo científico publicado en 1993

In vivo 'Purging' of residual disease in CLL with Campath-1H

artículo científico publicado en 1997

In vivo CAMPATH-1H prevents GvHD following nonmyeloablative stem-cell transplantation

artículo científico publicado en 2001

In vivo CAMPATH-1H prevents graft-versus-host disease following nonmyeloablative stem cell transplantation

artículo científico publicado en 2000

In vivo kinetics of GITR and GITR ligand expression and their functional significance in regulating viral immunopathology

artículo científico publicado en 2005

In vivo transfer of GPI-linked complement restriction factors from erythrocytes to the endothelium

scientific article published in Science

In vivo use of Campath-1G to prevent graft-versus-host disease and graft rejection after bone marrow transplantation

artículo científico publicado en 1992

Incidence and outcome of adenovirus disease in transplant recipients after reduced-intensity conditioning with alemtuzumab

artículo científico publicado en 2004

Induced Foxp3(+) T Cells Colonizing Tolerated Allografts Exhibit the Hypomethylation Pattern Typical of Mature Regulatory T Cells

artículo científico publicado en 2016

Induction of Immunological Tolerance as a Therapeutic Procedure

artículo científico publicado en 2016

Induction of Immunological Tolerance/Hyporesponsiveness in Baboons with a Nondepleting CD4 Antibody

artículo científico publicado en 2004

Induction of Regulatory T Cells and Dominant Tolerance by Dendritic Cells Incapable of Full Activation

scientific article published on 01 July 2007

Induction of classical transplantation tolerance in the adult

artículo científico publicado en 1989

Induction of dominant transplantation tolerance by an altered peptide ligand of the male antigen Dby.

artículo científico publicado en 2004

Induction of foxP3+ regulatory T cells in the periphery of T cell receptor transgenic mice tolerized to transplants

artículo científico publicado en 2004

Induction of tolerance by monoclonal antibody therapy

artículo científico publicado en 1986

Induction of tolerance in peripheral T cells with monoclonal antibodies

artículo científico publicado en 1990

Infectious tolerance ⬇️

artículo científico publicado el 1 de octubre de 1998

Infectious tolerance and the long-term acceptance of transplanted tissue

artículo científico publicado en 2006

Infectious tolerance via the consumption of essential amino acids and mTOR signaling

artículo científico publicado en 2009

Infectious tolerance. What are we missing?

artículo científico publicado en 2020

Infectious tolerance: therapeutic potential

scientific article published on 07 September 2010

Influence of the major histocompatibility complex on lymphocyte interactions in antibody formation ⬇️

artículo científico publicado el 13 de julio de 1978

Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes

artículo científico publicado en 2005

Interaction of rat monoclonal antibodies with human killer cells

Interaction of rat monoclonal antibodies with human killer cells (K cells)

artículo científico publicado en 1984

Interactions between T and B Cells: A Review ⬇️

artículo científico publicado el 1 de marzo de 1979

Isolation and expression of cDNA encoding the canine CD4 and CD8α antigens

artículo científico publicado en 1994

Isolation of low-frequency class-switch variants from rat hybrid myelomás

scientific article published on 01 October 1987

Key role of the GITR/GITRLigand pathway in the development of murine autoimmune diabetes: a potential therapeutic target

artículo científico publicado en 2009

L3T4 and Lyt-2 T cells are both involved in the generation of low-dose streptozotocin-induced diabetes in mice

scientific article published on 01 December 1987

Leukaemic relapse after Campath 1-treated bone-marrow transplantation for leukaemia

artículo científico publicado en 1987

Limiting dilution analysis of cells of the immune system II: What can be learnt?

artículo científico

Limiting dilution analysis of the cells of immune system I. The clonal basis of the immune response

artículo científico publicado en 1984

Limiting transplantation-related mortality following unrelated donor stem cell transplantation by using a nonmyeloablative conditioning regimen

artículo científico publicado en 2002

Linked suppression of skin graft rejection can operate through indirect recognition

artículo científico publicado en 1998

Long-term remission of intractable systemic vasculitis with monoclonal antibody therapy

artículo científico publicado en 1993

Long-term survival after lymphocytotoxic monoclonal antibody therapy for rheumatoid arthritis.

artículo científico publicado en 2005

Loss of the TGFβ-activating integrin αvβ8 on dendritic cells protects mice from chronic intestinal parasitic infection via control of type 2 immunity.

artículo científico publicado en 2013

Low dose unresponsiveness with a thymus independent antigen

artículo científico publicado en 1975

Lymphocyte homeostasis following therapeutic lymphocyte depletion in multiple sclerosis

artículo científico publicado en 2005

MS4A4B is a GITR-associated membrane adapter, expressed by regulatory T cells, which modulates T cell activation

artículo científico publicado en 2009

Matched unrelated donor bone marrow transplantation for chronic myeloid leukaemia in chronic phase: comparison of ex vivo and in vivo T-cell depletion.

artículo científico publicado en 1993

Mechanism of first-dose cytokine-release syndrome by CAMPATH 1-H: involvement of CD16 (FcgammaRIII) and CD11a/CD18 (LFA-1) on NK cells

artículo científico publicado en 1996

Mechanism of recovery from acute virus infection: treatment of lymphocytic choriomeningitis virus-infected mice with monoclonal antibodies reveals that Lyt-2+ T lymphocytes mediate clearance of virus and regulate the antiviral antibody response

artículo científico publicado en 1987

Mechanisms in CD4 antibody-mediated transplantation tolerance: kinetics of induction, antigen dependency and role of regulatory T cells.

artículo científico publicado en 1994

Mechanisms of Antibody Immunotherapy on Clonal Islet Reactive T Cells

artículo científico publicado en 2006

Mechanisms of immunological tolerance

artículo científico

Mechanisms of monoclonal antibody-facilitated tolerance induction: a possible role for the CD4 (L3T4) and CD11a (LFA-1) molecules in self-non-self discrimination

artículo científico publicado en 1988

Mechanisms of peripheral tolerance and suppression induced by monoclonal antibodies to CD4 and CD8.

artículo científico publicado en 1996

Minimum Information about T Regulatory Cells: A Step toward Reproducibility and Standardization

artículo científico publicado en 2017

Monoclonal antibodies as agents to reinduce tolerance in autoimmunity.

artículo científico publicado en 1992

Monoclonal antibodies for immunosuppression

artículo científico publicado en 1988

Monoclonal antibodies for the depletion of specific subpopulations of lymphocytes.

artículo científico publicado en 1987

Monoclonal antibodies for the induction of transplantation tolerance

artículo científico publicado en 1993

Monoclonal antibodies for the prevention of graft-versus-host disease and marrow graft rejection. The depletion of T cell subsets in vitro and in vivo

artículo científico publicado en 1986

Monoclonal antibodies for the therapeutic induction of tolerance

artículo científico publicado en 1993

Monoclonal antibodies to haemopoietic cells

Monoclonal antibodies to promote marrow engraftment and tissue graft tolerance

artículo científico publicado en 1986

Monoclonal antibody therapy of chronic intraocular inflammation using Campath-1H.

artículo científico publicado en 1995

Monoclonal antibody therapy of diffuse cutaneous scleroderma with CAMPATH-1H.

artículo científico

Monoclonal antibody treatment exposes three mechanisms underlying the clinical course of multiple sclerosis

artículo científico publicado en 1999

Monoclonal-Antibody Therapy in Systemic Vasculitis

artículo científico publicado en 1990

Monoclonals and marrow transplants

artículo científico publicado en 1986

Monocytic origin of foam cells in human atherosclerotic plaques

artículo científico publicado en 1984

Monogamous T helper cell ⬇️

artículo científico publicado el 18 de agosto de 1977

Morbidity and mortality in rheumatoid arthritis patients with prolonged and profound therapy-induced lymphopenia

artículo científico publicado en 2001

Morbidity and mortality in rheumatoid arthritis patients with prolonged therapy-induced lymphopenia: twelve-year outcomes

artículo científico publicado en 2008

Mouse glucocorticoid-induced tumor necrosis factor receptor ligand is costimulatory for T cells

scientific journal article

Myeloablative conditioning is well tolerated by older patients receiving T-cell-depleted grafts

artículo científico publicado en 2005

Neutralizing TNF-alpha activity modulates T-cell phenotype and function in experimental autoimmune uveoretinitis

artículo científico publicado en 1998

Neutralizing tumor necrosis factor activity leads to remission in patients with refractory noninfectious posterior uveitis

artículo científico publicado en 2004

Non-Invasive Multiphoton Imaging of Islets Transplanted Into the Pinna of the NOD Mouse Ear Reveals the Immediate Effect of Anti-CD3 Treatment in Autoimmune Diabetes.

artículo científico publicado en 2018

Non-depleting anti-CD4 monoclonal antibody induces immune tolerance to ERT in a murine model of Pompe disease

artículo científico publicado en 2014

Nutrient Sensing via mTOR in T Cells Maintains a Tolerogenic Microenvironment

artículo científico publicado en 2014

P1. Immunoablation with t cell depleted autologous peripheral blood stem cell rescue produces complete remission in thrombocytopenic purpura (TTP) recidivant and refractory to standard treatment

PHASE I STUDY OF AN ENGINEERED AGLYCOSYLATED HUMANIZED CD3 ANTIBODY IN RENAL TRANSPLANT REJECTION1

artículo científico publicado en 1999

Partial and transient modulation of the CD3-T-cell receptor complex, elicited by low-dose regimens of monoclonal anti-CD3, is sufficient to induce disease remission in non-obese diabetic mice

artículo científico publicado en 2010

Pathogenic mechanisms in murine autoimmune thyroiditis: short- and long-term effects of in vivo depletion of CD4+ and CD8+ cells

scientific article published on 01 September 1989

Pediatric immunohematopoietic stem cell transplantation at a tertiary care center in Cape Town

artículo científico publicado en 2008

Peripheral tolerance mechanisms prevent the development of autoreactive T cells in chimeras grafted with two minor incompatible thymuses

article

Pharmacokinetics and antibody responses to the CD3 antibody otelixizumab used in the treatment of type 1 diabetes.

artículo científico publicado en 2010

Phase II trial of subcutaneous anti-CD52 monoclonal antibody alemtuzumab (Campath-1H) as first-line treatment for patients with B-cell chronic lymphocytic leukemia (B-CLL).

artículo científico publicado en 2002

Pilot study of CAMPATH-1, a rat monoclonal antibody that fixes human complement, as an immunosuppressant in organ transplantation

artículo científico publicado en 1986

Plasticity of Foxp3(+) T cells reflects promiscuous Foxp3 expression in conventional T cells but not reprogramming of regulatory T cells.

artículo científico publicado en 2012

Posttranscriptional regulation of IL-10 gene expression through sequences in the 3'-untranslated region.

artículo científico publicado en 2000

Preliminary evidence from magnetic resonance imaging for reduction in disease activity after lymphocyte depletion in multiple sclerosis

artículo científico publicado en 1994

Preliminary experience of allogeneic stem cell transplantation for lymphoproliferative disorders using BEAM-CAMPATH conditioning: an effective regimen with low procedure-related toxicity

article

Preservation of recall immunity in anti-CD3-treated recent onset type 1 diabetes patients

artículo científico publicado en 2011

Prevention of Diabetes but not Insulitis in NOD Mice Injected with Antibody to CD4

artículo científico publicado en 1993

Prevention of immune-mediated corneal graft destruction with the anti-lymphocyte monoclonal antibody, CAMPATH-1H

artículo científico publicado en 1995

Probing dendritic cell function by guiding the differentiation of embryonic stem cells

artículo científico publicado en 2003

Prope tolerance with induction using Campath 1H and low-dose cyclosporin monotherapy in 31 cadaveric renal allograft recipients

scientific article published on 01 March 2000

Prope tolerance, perioperative campath 1H, and low-dose cyclosporin monotherapy in renal allograft recipients

artículo científico publicado en 1998

Properties of educated T cells. The ability of educated T cells to facilitate the immune response to non-cross-reacting antigensin vitro

article published in 1973

Prophylactic use of an antilymphocyte monoclonal antibody following renal transplantation: a randomized controlled trial

artículo científico publicado en 1987

Prospects for ensuring acceptance of ES cell-derived tissues

artículo científico publicado en 2010

Protection and privilege

artículo científico publicado en 2006

Pulsed monoclonal antibody treatment and autoimmune thyroid disease in multiple sclerosis

artículo científico publicado en 1999

Purging in auto- and allografts: monoclonal antibodies which use human complement and other natural effector mechanisms

artículo científico publicado en 1990

REMISSION INDUCTION IN NON-HODGKIN LYMPHOMA WITH RESHAPED HUMAN MONOCLONAL ANTIBODY CAMPATH-1H

artículo científico publicado en 1988

Radiotherapy-based conditioning is effective immunosuppression for patients undergoing transplantation with T-cell depleted stem cell grafts for severe aplasia

artículo científico publicado en 2004

Rat monoclonal antibodies for bone marrow transplantation--the CAMPATH series

artículo científico publicado en 1985

Reactivity of rat monoclonal antibody CAMPATH-1 with human leukaemia cells and its possible application for autologous bone marrow transplantation

artículo científico publicado en 1985

Recent results using CAMPATH-1 antibodies to control GVHD and graft rejection

artículo científico publicado en 1996

Reconstitution of the Epstein-Barr virus-specific cytotoxic T-lymphocyte response following T-cell-depleted myeloablative and nonmyeloablative allogeneic stem cell transplantation

artículo científico publicado en 2003

Reduced-intensity transplantation with in vivo T-cell depletion and adjuvant dose-escalating donor lymphocyte infusions for chemotherapy-sensitive myeloma: Limited efficacy of graft-versus-tumor activity

scientific article published on 01 April 2003

Regulating the immune response to transplants. a role for CD4+ regulatory cells?

artículo científico publicado en 2001

Regulation and privilege in transplantation

Regulation and privilege in transplantation tolerance

artículo científico publicado en 2008

Regulation of CD40 function by its isoforms generated through alternative splicing

artículo científico publicado en 2001

Regulation of IL-18 (IFN-gamma-inducing factor) gene expression ⬇️

artículo científico publicado el 15 de diciembre de 1997

Regulation of the immune response

artículo científico publicado en 2010

Regulatory T Cells Promote Apelin-Mediated Sprouting Angiogenesis in Type 2 Diabetes

artículo científico publicado en 2018

Regulatory T cells and dendritic cells in transplantation tolerance: molecular markers and mechanisms

artículo científico publicado en 2003

Regulatory T cells and organ transplantation

artículo científico publicado en 2004

Regulatory T cells and transplantation tolerance.

artículo científico publicado en 2013

Regulatory T cells in the induction and maintenance of peripheral transplantation tolerance

artículo científico publicado en 2003

Regulatory T cells in transplantation

artículo científico publicado en 2006

Regulatory T cells overexpress a subset of Th2 gene transcripts

artículo científico publicado en 2002

Regulatory T cells: context matters

artículo científico publicado en 2009

Regulatory cells and transplantation tolerance

artículo científico publicado en 2013

Rejection of H-Y disparate skin grafts by monospecific CD4+ Th1 and Th2 cells: no requirement for CD8+ T cells or B cells.

artículo científico publicado en 1998

Remission Induction in Patients with Lymphoid Malignancies Using Unconjugated CAMPATH-1 Monoclonal Antibodies.

artículo científico publicado en 1990

Removal of T cells from bone marrow for transplantation. Comparison of rat monoclonal anti-lymphocyte antibodies of different isotypes

artículo científico publicado en 1983

Removal of T cells from bone marrow for transplantation: a monoclonal antilymphocyte antibody that fixes human complement

artículo científico publicado en 1983

Reprogramming the immune system

artículo científico publicado en 2002

Reprogramming the immune system

artículo científico publicado en 2008

Reprogramming the immune system for peripheral tolerance with CD4 and CD8 monoclonal antibodies

artículo científico publicado en 1992

Reprogramming the immune system for tolerance with monoclonal antibodies

artículo científico publicado en 1990

Reprogramming the immune system using antibodies.

artículo científico publicado en 2006

Reprogramming the immune system: a possible therapeutic approach to established autoimmune disease

artículo científico publicado en 1993

Reprogramming the immune system: co-receptor blockade as a paradigm for harnessing tolerance mechanisms

artículo científico publicado en 2008

Reshaping a therapeutic CD4 antibody

artículo científico publicado en 1991

Reshaping human antibodies for therapy

artículo científico publicado en 1988

Resistance of regulatory T cells to glucocorticoid-induced [corrected] TNFR family-related protein (GITR) during Plasmodium yoelii infection.

artículo científico publicado en 2005

Resistance to experimental autoimmune thyroiditis: L3T4+ cells as mediators of both thyroglobulin-activated and TSH-induced suppression.

artículo científico publicado en 1989

Respiratory virus infections in transplant recipients after reduced-intensity conditioning with Campath-1H: high incidence but low mortality

artículo científico publicado en 2002

Reversal of allograft rejection using the monoclonal antibody, Campath-1G

artículo científico publicado en 1991

Risks of developing Epstein-Barr virus-related lymphoproliferative disorders after T-cell-depleted marrow transplants. CAMPATH Users.

artículo científico publicado en 1998

SAGE Analysis of Cell Types Involved in Tolerance Induction

SAGE analysis of cell types involved in tolerance induction

artículo científico publicado en 2007

SKIN ALLOGRAFT REJECTION BY L3/t4+ AND LYT-2+ T CELL SUBESTS

artículo científico publicado en 1986

STRAIN VARIATION IN SUSCEPTIBILITY TO MONOCLONAL ANTIBODY-INDUCED TRANSPLANTATION TOLERANCE1

artículo científico publicado en 1997

Secreted and transmembrane 1A is a novel co-stimulatory ligand

artículo científico publicado en 2013

Segregation of mouse hemopoietic progenitor cells using the monoclonal antibody, YBM/42

artículo científico publicado en 1983

Selective isolation of murine erythropoietin-responsive progenitor cells (CFU-E) with monoclonal antibodies

scientific article published on 01 July 1983

Self tolerance is H–2-restricted

artículo científico publicado en 1984

Semi-specific immuno-absorption and monoclonal antibody therapy in ANCA positive vasculitis: experience in four cases

artículo científico publicado en 1998

Separation of hemopoietic cells from adult mouse marrow by use of monoclonal antibodies ⬇️

artículo científico publicado el 1 de marzo de 1983

Sequence of a rat immunoglobulin gamma 2c heavy chain constant region cDNA: extensive homology to mouse gamma 3.

artículo científico publicado en 1988

Serial analysis of gene expression provides new insights into regulatory T cells

artículo científico publicado en 2003

Single-cell transcriptomics reveal that PD-1 mediates immune tolerance by regulating proliferation of regulatory T cells

scholarly article by Cherry S Leung published in September 2018

Sparing of first dose effect of monovalent anti-CD3 antibody used in allograft rejection is associated with diminished release of pro-inflammatory cytokines

scientific article published on 01 December 1994

Special regulatory T cell review: The suppression problem!

artículo científico publicado en 2008

Specific subsets of murine dendritic cells acquire potent T cell regulatory functions following CTLA4-mediated induction of indoleamine 2,3 dioxygenase

artículo científico publicado en 2004

Specificity of monoclonal antibody Campath-1

scientific article published on 01 May 1988

Stability of tolerance in mice generated by CD4 and CD8 monoclonal antibody treatment: cell transfer experiments

scientific article published on 01 February 1993

Stable lines of genetically modified dendritic cells from mouse embryonic stem cells

artículo científico publicado en 2003

Structural basis for ligand-mediated mouse GITR activation

artículo científico publicado en 2008

Structural motifs involved in human IgG antibody effector functions

artículo científico publicado en 1993

Structure and chromosomal location of mouse and human CD52 genes

artículo científico publicado en 1999

Structure and chromosomal location of the mouse interleukin-12 p35 and p40 subunit genes

artículo científico publicado en 1996

Structure of the CAMPATH-1 antigen, a glycosylphosphatidylinositol-anchored glycoprotein which is an exceptionally good target for complement lysis

artículo científico publicado en 1993

Substantial peripheral T-cell depletion before grafting is beneficial in islet transplantation

artículo científico publicado en 1995

Successful attenuation of humoral immunity to viral capsid and transgenic protein following AAV-mediated gene transfer with a non-depleting CD4 antibody and cyclosporine

artículo científico publicado en 2011

Successful haploidentical mismatched bone marrow transplantation in severe combined immunodeficiency: T cell removal using CAMPATH-I monoclonal antibody and E-rosetting

artículo científico publicado en 1986

Suppression in murine experimental autoimmune thyroiditis: in vivo inhibition of CD4+ T cell-mediated resistance by a nondepleting rat CD4 monoclonal antibody

artículo científico publicado en 1991

Sustained remission of severe resistant autoimmune neutropenia with Campath-1H

artículo científico publicado en 1997

Sustained suppression by Foxp3+ regulatory T cells is vital for infectious transplantation tolerance

artículo científico publicado en 2011

Synergistic complement lysis by monoclonal antibodies to the human leukocyte common antigen requires both the classical and alternative pathways

artículo científico publicado en 1987

Synergistic monoclonal antibodies for in vitro immunomodulation of dog islets

artículo científico publicado el 1 de junio de 1992

T Cell-dependent Mediator in the Immune Response

artículo científico publicado en 1973

T cell dependence of B cell unresponsivenessin vitro

artículo científico publicado en 1974

T cell depletion by exposure to Campath-1G in vitro prevents graft-versus-host disease

artículo científico publicado en 1994

T cell depletion with CAMPATH-1 in allogeneic bone marrow transplantation

scientific article published on 01 April 1988

T cell regulation in adult transplantation tolerance

scientific article published on 01 July 1996

T cell sensitivity to HLA class I-mediated apoptosis is dependent on interleukin-2 and interleukin-4

artículo científico publicado en 1997

T cell suppression in transplantation tolerance through linked recognition.

artículo científico publicado en 1996

T- and B-cell immune reconstitution and clinical outcome in patients with multiple myeloma receiving T-cell-depleted, reduced-intensity allogeneic stem cell transplantation with an alemtuzumab-containing conditioning regimen followed by escalated don

artículo científico publicado en 2003

T-cell depletion with Campath-1H 'in the bag' for matched related allogeneic peripheral blood stem cell transplantation is associated with reduced graft-versus-host disease, rapid immune constitution and improved survival

artículo científico publicado en 2003

T-cell killing of target cells induced by hybrid antibodies: comparison of two bispecific monoclonal antibodies

artículo científico publicado en 1987

T-cell-depleted allogeneic bone marrow transplantation for acute leukaemia using Campath-1 antibodies and post-transplant administration of donor's peripheral blood lymphocytes for prevention of relapse

artículo científico publicado en 1995

TGF-β in transplantation tolerance

artículo científico

TGF-β-mediated Foxp3 gene expression is cooperatively regulated by Stat5, Creb, and AP-1 through CNS2.

artículo científico publicado en 2013

THERAPEUTIC POTENTIAL OF MONOCLONAL ANTIBODIES TO THE LEUKOCYTE-COMMON ANTIGEN

artículo científico publicado en 1985

TOLERANCE AND SUPPRESSION IN A PRIMED IMMUNE SYSTEM1

artículo científico publicado en 1996

Th17 cells induce a distinct graft rejection response that does not require IL-17A.

artículo científico publicado en 2012

The CAMPATH-1 antigen (CDw52)

artículo científico publicado en 1990

The CD59 antigen--a multifunctional molecule

artículo científico publicado en 1992

The Induction and Maintenance of Transplant Tolerance Engages Both Regulatory and Anergic CD4+ T cells

artículo científico publicado en 2017

The Influence of the Major Histocompatibility Complex on the Function of T-Helper Cells in Antibody Formation ⬇️

artículo científico publicado el 1 de enero de 1978

The Role of Lipid Metabolism in T Lymphocyte Differentiation and Survival

artículo científico publicado en 2017

The anti-IL-2 receptor monoclonal antibody YTH-906 in liver transplantation

artículo científico publicado en 1991

The characterisation of monoclonal antibodies against haemopoietic cells: Comparison of an immunoperoxidase method with fluorescence activated cell sorting

scientific article published on 01 July 1983

The development of insulin-dependent diabetes mellitus in non-obese diabetic mice: the role of CD4+ and CD8+ T cells

article

The effect of aglycosylation on the immunogenicity of a humanized therapeutic CD3 monoclonal antibody.

artículo científico publicado en 1995

The effect of the serotherapy regimen used and the marrow cell dose received on rejection, graft-versus-host disease and outcome following unrelated donor bone marrow transplantation for leukaemia.

artículo científico publicado en 2000

The effect of treatment with Campath-1H in patients with autoimmune cytopenias

artículo científico publicado en 2001

The failure to show a necessary role for C3 in thein vitro antibody response

artículo científico publicado en 1975

The generation of a humanized, non-mitogenic CD3 monoclonal antibody which retains in vitro immunosuppressive properties

artículo científico publicado en 1993

The human interleukin 18 gene IL18 maps to 11q22.2-q22.3, closely linked to the DRD2 gene locus and distinct from mapped IDDM loci

artículo científico publicado en 1998

The immunogenicity of chimeric antibodies

artículo científico publicado en 1989

The improved lytic function andin vivo efficacy of monovalent monoclonal CD3 antibodies

scientific article published on 01 February 1989

The induction of skin graft tolerance in major histocompatibility complex-mismatched or primed recipients: primed T cells can be tolerized in the periphery with anti-CD4 and anti-CD8 antibodies

artículo científico publicado en 1990

The influence of thymus on the development of MHC restrictions exhibited by T-helper cells ⬇️

artículo científico publicado el 11 de enero de 1979

The involvement of Ly 2+ T cells in beta cell destruction

scientific article published on 01 April 1990

The new immunosuppression

artículo científico publicado en 2003

The new immunosuppression: intervention at the dendritic cell-T-cell interface.

artículo científico publicado en 2005

The new immunosuppression: just kill the T cell ⬇️

artículo científico publicado el 1 de octubre de 2003

The nuclear orphan receptor Nr4a2 induces Foxp3 and regulates differentiation of CD4+ T cells ⬇️

artículo científico publicado en 2011

The plasticity and stability of regulatory T cells

artículo científico publicado en 2013

The potential of hybrid antibodies secreted by hybrid-hybridomas in tumour therapy

artículo científico publicado en 1988

The relationship between pityriasis rubra pilaris and inflammatory arthritis: Case report and response of the arthritis to anti-tumor necrosis factor immunotherapy

article

The repopulation capacity of bone marrow grafts following pretreatment with monoclonal antibodies against T lymphocytes in rhesus monkeys

scientific article published on 01 February 1988

The role of CD4+ T‐cell subsets in determining transplantation rejection or tolerance ⬇️

artículo científico publicado el 1 de agosto de 2001

The role of Sp1 and NF-kappa B in regulating CD40 gene expression

artículo científico publicado en 2001

The use of a non-depleting anti-CD4 monoclonal antibody to re-establish tolerance to beta cells in NOD mice.

artículo científico publicado en 1992

The use of monoclonal antibodies against activated human T cells following renal allografting in the baboon

scientific article published on 01 October 1987

The use of monoclonal antibodies to achieve immunological tolerance

scientific article published on 01 June 1993

The use of monoclonal antibodies to achieve immunological tolerance.

artículo científico publicado en 1993

The vaccinia virus C12L protein inhibits mouse IL-18 and promotes virus virulence in the murine intranasal model

artículo científico publicado en 2002

The window of therapeutic opportunity in multiple sclerosis: evidence from monoclonal antibody therapy

artículo científico publicado en 2005

Therapeutic approaches for transplantation.

artículo científico publicado en 2001

Therapeutic aspects of tolerance.

artículo científico publicado en 2001

Therapeutic potential of monoclonal antibodies to the leucocyte common antigen

artículo científico publicado en 1985

Therapeutic potential of monovalent monoclonal antibodies

artículo científico publicado en 1984

Therapeutic potential of rat monoclonal antibodies: isotype specificity of antibody-dependent cell-mediated cytotoxicity with human lymphocytes

artículo científico publicado en 1985

Therapy with monoclonal antibodies by elimination of T-cell subsets in vivo

artículo científico publicado en 1984

Therapy with monoclonal antibodies. An in vivo model for the assessment of therapeutic potential ⬇️

artículo científico publicado el 15 de mayo de 1992

Therapy with monoclonal antibodies. II. The contribution of Fc gamma receptor binding and the influence of C(H)1 and C(H)3 domains on in vivo effector function

artículo científico publicado en 1998

Tmem176B and Tmem176A are associated with the immature state of dendritic cells

scientific journal article

Tolerance Induction with CD4 Monoclonal Antibodies ⬇️

artículo científico publicado el 1 de enero de 1998

Tolerance can be infectious

scientific article published on 01 September 2008

Tolerance in the mouse to major histocompatibility complex-mismatched heart allografts, and to rat heart xenografts, using monoclonal antibodies to CD4 and CD8

scientific article published on 01 March 1992

Tolerance induction in concordant heart-xenografted mice by CD4 and CD8 monoclonal antibodies

scientific article published on 01 June 1994

Tolerance induction in the adult using monoclonal antibodies to CD4, CD8, and CD11a (LFA-1)

scientific article published on 01 January 1989

Tolerance induction in the adult: 'danger' at Le Bischenberg.

artículo científico publicado en 1995

Tolerance induction to human stem cell transplants with extension to their differentiated progeny

artículo científico publicado en 2014

Tolerance to IDDM Induced by CD4 Antibodies in Nonobese Diabetic Mice is Reversed by Cyclophosphamide

scientific article published on 01 November 1993

Tolerance to rat monoclonal antibodies. Implications for serotherapy

artículo científico publicado en 1986

Tolerance: an overview and perspectives

scientific article published on 17 August 2010

Tolerogenicity is not an absolute property of a dendritic cell

artículo científico publicado en 2010

Transfection of human CD59 complementary DNA into rat cells confers resistance to human complement

artículo científico publicado en 1991

Transient Epstein-Barr virus reactivation in CD3 monoclonal antibody-treated patients

scientific article published on 09 December 2009

Transient increase in symptoms associated with cytokine release in patients with multiple sclerosis

artículo científico publicado en 1996

Transplantation

Transplantation

Transplantation

Transplantation tolerance: the big picture. Where do we stand, where should we go?

artículo científico publicado en 2017

Transplantation—caught in the crossfire!

scientific article published on 01 September 2002

Treatment of refractory Wegener's granulomatosis with humanized monoclonal antibodies

artículo científico publicado en 1996

Universal bispecific antibody for targeting tumor cells for destruction by cytotoxic T cells

artículo científico publicado en 1988

Unrelated donor bone marrow transplant in childhood ALL. The role of T-cell depletion

Unrelated donor bone marrow transplantation for children with relapsed acute lymphoblastic leukaemia in second complete remission

artículo científico publicado en 1996

Use of Ceprate CD34-positive selection system for depletion of T cells in allogeneic transplantation ⬇️

artículo científico publicado el 1 de octubre de 1997

What can be done to prevent graft versus host disease?

artículo científico publicado en 1994

mTOR signalling and metabolic regulation of T cell differentiation

artículo científico publicado en 2010

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