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Lista de obras de Kaiwen W Chen

A novel flow cytometric method to assess inflammasome formation

artículo científico publicado en 2014

Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner.

artículo científico publicado en 2017

An antioxidant role for catecholate siderophores in Salmonella.

artículo científico publicado en 2013

Antimicrobial functions of inflammasomes

artículo científico

Beyond inflammasomes: emerging function of gasdermins during apoptosis and NETosis

scientific article published on 03 December 2019

Burn the house, save the day: pyroptosis in pathogen restriction

scholarly article published 1 January 2016

Caspase-1 cleaves Bid to release mitochondrial SMAC and drive secondary necrosis in the absence of GSDMD

artículo científico publicado en 2020

Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity.

artículo científico publicado en 2018

Caspase-8-dependent gasdermin D cleavage promotes antimicrobial defense but confers susceptibility to TNF-induced lethality

scientific article published on 18 November 2020

Cutting Edge: Blockade of Inhibitor of Apoptosis Proteins Sensitizes Neutrophils to TNF- but Not Lipopolysaccharide-Mediated Cell Death and IL-1β Secretion.

artículo científico publicado en 2018

Divide to conquer: NLRP3 is activated on dispersed trans-Golgi network

scientific article published on 01 March 2019

Extrinsic and intrinsic apoptosis activate pannexin-1 to drive NLRP3 inflammasome assembly

scientific article published on 22 March 2019

Genetic targeting of Card19 is linked to disrupted NINJ1 expression, impaired cell lysis, and increased susceptibility to Yersinia infection

artículo científico publicado en 2021

Human GBP1 binds LPS to initiate assembly of a caspase-4 activating platform on cytosolic bacteria

artículo científico publicado en 2020

Inflammasomes and Inflammation

Interleukin-1β Maturation Triggers Its Relocation to the Plasma Membrane for Gasdermin-D-Dependent and -Independent Secretion

artículo científico publicado en 2018

NLRP12 is a neutrophil-specific, negative regulator of in vitro cell migration but does not modulate LPS- or infection-induced NF-κB or ERK signalling

artículo científico publicado en 2015

Noncanonical inflammasome signaling elicits gasdermin D–dependent neutrophil extracellular traps

artículo científico publicado en 2018

Pannexin-1 channels bridge apoptosis to NLRP3 inflammasome activation

artículo científico publicado en 2019

Pannexin-1 promotes NLRP3 activation during apoptosis but is dispensable for canonical or noncanonical inflammasome activation

artículo científico publicado en 2019

Rab8a interacts directly with PI3Kγ to modulate TLR4-driven PI3K and mTOR signalling

artículo científico publicado en 2014

The murine neutrophil NLRP3 inflammasome is activated by soluble but not particulate or crystalline agonists

artículo científico publicado en 2016

The neutrophil NLRC4 inflammasome selectively promotes IL-1β maturation without pyroptosis during acute Salmonella challenge

artículo científico publicado en 2014

XIAP Loss Triggers RIPK3- and Caspase-8-Driven IL-1β Activation and Cell Death as a Consequence of TLR-MyD88-Induced cIAP1-TRAF2 Degradation.

artículo científico