Lista de obras - Luisa Minghetti - Dominio Público Uruguay

15-deoxy-delta12,14-prostaglandin J2 regulates the functional state and the survival of microglial cells through multiple molecular mechanisms.

artículo científico publicado en 2003

Activation of alpha7 nicotinic acetylcholine receptor by nicotine selectively up-regulates cyclooxygenase-2 and prostaglandin E2 in rat microglial cultures

artículo científico publicado en 2005

Adenosine A(2A) receptors modulate BDNF both in normal conditions and in experimental models of Huntington's disease.

artículo científico publicado en 2007

Adenosine A2A receptor antagonism and neuroprotection: mechanisms, lights, and shadows.

artículo científico publicado en 2004

Adenosine A2A receptor stimulation restores cell functions and differentiation in Niemann-Pick type C-like oligodendrocytes

scientific article published on 05 July 2019

Altered expression of cyclooxygenase-2, presenilins and oxygen radical scavenging enzymes in a rat model of global perinatal asphyxia

artículo científico publicado en 2007

Astrocytes contribute to neuronal impairment in beta A toxicity increasing apoptosis in rat hippocampal neurons.

artículo científico publicado en 2001

Atypical antiinflammatory activation of microglia induced by apoptotic neurons: possible role of phosphatidylserine-phosphatidylserine receptor interaction.

artículo científico publicado en 2004

Branched-chain amino acids influence the immune properties of microglial cells and their responsiveness to pro-inflammatory signals.

artículo científico publicado en 2013

Cerebrospinal fluid isoprostanes are not related to inflammatory activity in relapsing-remitting multiple sclerosis

artículo científico publicado en 2004

Cognitive and neurological deficits induced by early and prolonged basal forebrain cholinergic hypofunction in rats

artículo científico publicado en 2004

Critical Role of Maternal Selenium Nutrition in Neurodevelopment: Effects on Offspring Behavior and Neuroinflammatory Profile

artículo científico publicado en 2022

Cyclo-oxygenase-1 and -2 differently contribute to prostaglandin E2 synthesis and lipid peroxidation after in vivo activation of N-methyl-D-aspartate receptors in rat hippocampus.

artículo científico publicado en 2005

Cyclooxygenase-2 is highly expressed in microglial-like cells in a murine model of prion disease

scientific article published on 01 February 2000

Cyclooxygenase-2, prostaglandin E2, and microglial activation in prion diseases

artículo científico publicado en 2007

Deletion of the life span determinant p66Shc prevents age-dependent increases in emotionality and pain sensitivity in mice.

artículo científico publicado en 2006

Deletion of the lifespan determinant p66(Shc) improves performance in a spatial memory task, decreases levels of oxidative stress markers in the hippocampus and increases levels of the neurotrophin BDNF in adult mice.

artículo científico publicado en 2007

Differential effects of the nonsteroidal antiinflammatory drug flurbiprofen and its nitric oxide-releasing derivative, nitroflurbiprofen, on prostaglandin E(2), interleukin-1beta, and nitric oxide synthesis by activated microglia.

artículo científico publicado en 2001

Docosahexaenoic acid modulates inflammatory and antineurogenic functions of activated microglial cells

scientific article published on 04 November 2011

Docosahexaenoic acid promotes oligodendrocyte differentiation via PPAR-γ signalling and prevents tumor necrosis factor-α-dependent maturational arrest.

artículo científico publicado en 2017

Dynamic regulation of microglial functions by the non-steroidal anti-inflammatory drug NCX 2216: implications for chronic treatments of neurodegenerative diseases.

artículo científico publicado en 2005

Early-life sex-dependent vulnerability to oxidative stress: the natural twining model.

artículo científico publicado en 2012

Effects of the adenosine A2A receptor antagonist SCH 58621 on cyclooxygenase-2 expression, glial activation, and brain-derived neurotrophic factor availability in a rat model of striatal neurodegeneration

artículo científico publicado en 2007

Functional characterization of substance P receptors on cultured human spinal cord astrocytes: Synergism of substance P with cytokines in inducing interleukin-6 and prostaglandin E2 production ⬇️

artículo científico publicado el 1 de octubre de 1997

Glycogen synthase kinase 3 is part of the molecular machinery regulating the adaptive response to LPS stimulation in microglial cells.

artículo científico publicado en 2015

Greater resistance to inflammation at adulthood could contribute to extended life span of p66(Shc-/-) mice.

artículo científico publicado en 2010

Human immunodeficiency virus type-1 Tat protein induces nuclear factor (NF)-kappaB activation and oxidative stress in microglial cultures by independent mechanisms.

artículo científico publicado en 2001

In vitro neuronal and glial differentiation from embryonic or adult neural precursor cells are differently affected by chronic or acute activation of microglia.

artículo científico publicado en 2008

In vivo activation of N-methyl-D-aspartate receptors in the rat hippocampus increases prostaglandin E(2) extracellular levels and triggers lipid peroxidation through cyclooxygenase-mediated mechanisms.

artículo científico publicado en 2002

Increased FUS levels in astrocytes leads to astrocyte and microglia activation and neuronal death

artículo científico publicado en 2019

Increased levels of acute-phase inflammatory proteins in plasma of patients with sporadic CJD.

artículo científico publicado en 2012

Inducible nitric oxide synthase expression in activated rat microglial cultures is downregulated by exogenous prostaglandin E2 and by cyclooxygenase inhibitors

scientific article published on 01 February 1997

Interaction between Gut Microbiota and Curcumin: A New Key of Understanding for the Health Effects of Curcumin

artículo científico publicado en 2020

Isoprostanes in clinically isolated syndrome and early multiple sclerosis as biomarkers of tissue damage and predictors of clinical course.

artículo científico publicado en 2012

Levels of CSF prostaglandin E2, cognitive decline, and survival in Alzheimer's disease.

artículo científico publicado en 2005

Maternal immune activation induces autism-like changes in behavior, neuroinflammatory profile and gut microbiota in mouse offspring of both sexes

artículo científico publicado en 2022

Microglia in development and disease

artículo científico publicado en 2013

Microglial activation in chronic neurodegenerative diseases: roles of apoptotic neurons and chronic stimulation

artículo científico publicado en 2005

Microglial polarization and plasticity: evidence from organotypic hippocampal slice cultures.

artículo científico publicado en 2013

Minocycline in phenotypic models of Huntington's disease

artículo científico publicado en 2005

Modulatory effects following subchronic stimulation of brain 5-HT7-R system in mice and rats.

artículo científico publicado en 2014

NGF promotes microglial migration through the activation of its high affinity receptor: modulation by TGF-beta.

artículo científico publicado en 2007

Non steroidal anti-inflammatory drugs and neurogenesis in the adult mammalian brain.

artículo científico publicado en 2008

Non-Steroidal Anti-Inflammatory Drugs and Brain Inflammation: Effects on Microglial Functions.

artículo científico publicado en 2010

Nonenzymatic oxygenated metabolites of α-linolenic acid B1- and L1-phytoprostanes protect immature neurons from oxidant injury and promote differentiation of oligodendrocyte progenitors through PPAR-γ activation

artículo científico publicado en 2014

Oxidative stress in twin neonates is influenced by birth weight and weight discordance ⬇️

artículo científico publicado el 22 de febrero de 2011

PPAR-gamma agonists as regulators of microglial activation and brain inflammation.

artículo científico publicado en 2006

Paracetamol effectively reduces prostaglandin E2 synthesis in brain macrophages by inhibiting enzymatic activity of cyclooxygenase but not phospholipase and prostaglandin E synthase

artículo científico publicado en 2003

Peroxisome proliferator activated receptor-γ agonists protect oligodendrocyte progenitors against tumor necrosis factor-alpha-induced damage: Effects on mitochondrial functions and differentiation.

artículo científico publicado en 2015

Peroxisome proliferator-activated receptor γ agonists accelerate oligodendrocyte maturation and influence mitochondrial functions and oscillatory Ca(2+) waves.

artículo científico publicado en 2011

Prenatal exposure to the organophosphate insecticide chlorpyrifos enhances brain oxidative stress and prostaglandin E2 synthesis in a mouse model of idiopathic autism

artículo científico publicado en 2016

Prolonged exposure of microglia to lipopolysaccharide modifies the intracellular signaling pathways and selectively promotes prostaglandin E2 synthesis.

artículo científico publicado en 2003

Prostaglandin E2 and BDNF levels in rat hippocampus are negatively correlated with status epilepticus severity: no impact on survival of seizure-generated neurons.

artículo científico publicado en 2006

Prostaglandin E2 synthesis is differentially affected by reactive nitrogen intermediates in cultured rat microglia and RAW 264.7 cells.

artículo científico publicado en 1997

Prostaglandin and thromboxane biosynthesis in isolated platelet-free human monocytes. I. A modified procedure for the characterization of the prostaglandin spectrum produced by resting and activated monocytes

artículo científico publicado en 1985

Prostaglandin and thromboxane biosynthesis in isolated platelet-free human monocytes. III. The induction of cycloxygenase by colony stimulating factor-1

artículo científico publicado en 1989

Purification and partial characterization of serum monocytotropic factor, a platelet-derived cyclooxygenase-inducing polypeptide.

artículo científico publicado en 1988

Regulation of Glial Cell Functions by PPAR-gamma Natural and Synthetic Agonists.

scientific article published on January 2008

Regulation of thromboxane A2 biosynthesis in platelet-free human monocytes and the possible role of polypeptide growth factor(s) in the induction of cyclooxygenase system

scientific article published on 01 May 1986

Reorientation of prostanoid production accompanies "activation" of adult microglial cells in culture

scientific article published on 01 August 1997

Restricted cyclooxygenase-2 expression in the central nervous system following acute and delayed-type hypersensitivity responses to bacillus Calmette-Guérin.

artículo científico publicado en 1999

Role of neuroinflammation in hypertension-induced brain amyloid pathology

artículo científico publicado en 2010

Role of the peroxisome proliferator-activated receptor-gamma (PPAR-gamma) and its natural ligand 15-deoxy-Delta12, 14-prostaglandin J2 in the regulation of microglial functions

artículo científico publicado en 2000

Stimulation of adenosine A2A receptors reduces intracellular cholesterol accumulation and rescues mitochondrial abnormalities in human neural cell models of Niemann-Pick C1.

artículo científico publicado en 2015

Striatal 6-OHDA lesion in mice: Investigating early neurochemical changes underlying Parkinson's disease

artículo científico publicado en 2009

TGF‐β and LPS modulate ADP‐induced migration of microglial cells through P2Y1 and P2Y12 receptor expression ⬇️

artículo científico publicado el 30 de agosto de 2010

Taking pain out of NGF: a "painless" NGF mutant, linked to hereditary sensory autonomic neuropathy type V, with full neurotrophic activity

artículo científico publicado en 2011

Targeting CXCR4 by a selective peptide antagonist modulates tumor microenvironment and microglia reactivity in a human glioblastoma model

artículo científico publicado en 2016

The mitochondrial uncoupling protein-2 is a master regulator of both M1 and M2 microglial responses.

artículo científico publicado en 2015

The nuclear receptor peroxisome proliferator-activated receptor-γ promotes oligodendrocyte differentiation through mechanisms involving mitochondria and oscillatory Ca2+ waves.

artículo científico

The presence of astrocytes enhances beta amyloid-induced neurotoxicity in hippocampal cell cultures.

artículo científico publicado en 2002

The stimulation of adenosine A2A receptors ameliorates the pathological phenotype of fibroblasts from Niemann-Pick type C patients.

artículo científico publicado en 2013

Transplacental exposure to AZT induces adverse neurochemical and behavioral effects in a mouse model: protection by L-acetylcarnitine

artículo científico publicado en 2013

Up-regulation of cyclooxygenase-2 expression in cultured microglia by prostaglandin E2, cyclic AMP and non-steroidal anti-inflammatory drugs

scientific article published on 01 May 1997

hMTH1 expression protects mitochondria from Huntington's disease-like impairment

artículo científico publicado en 2012

Lista de obras de Luisa Minghetti

15-deoxy-delta12,14-prostaglandin J2 regulates the functional state and the survival of microglial cells through multiple molecular mechanisms.

Activation of alpha7 nicotinic acetylcholine receptor by nicotine selectively up-regulates cyclooxygenase-2 and prostaglandin E2 in rat microglial cultures

Adenosine A(2A) receptors modulate BDNF both in normal conditions and in experimental models of Huntington's disease.

Adenosine A2A receptor antagonism and neuroprotection: mechanisms, lights, and shadows.

Adenosine A2A receptor stimulation restores cell functions and differentiation in Niemann-Pick type C-like oligodendrocytes

Altered expression of cyclooxygenase-2, presenilins and oxygen radical scavenging enzymes in a rat model of global perinatal asphyxia

Astrocytes contribute to neuronal impairment in beta A toxicity increasing apoptosis in rat hippocampal neurons.

Atypical antiinflammatory activation of microglia induced by apoptotic neurons: possible role of phosphatidylserine-phosphatidylserine receptor interaction.

Branched-chain amino acids influence the immune properties of microglial cells and their responsiveness to pro-inflammatory signals.

Cerebrospinal fluid isoprostanes are not related to inflammatory activity in relapsing-remitting multiple sclerosis

Cognitive and neurological deficits induced by early and prolonged basal forebrain cholinergic hypofunction in rats

Critical Role of Maternal Selenium Nutrition in Neurodevelopment: Effects on Offspring Behavior and Neuroinflammatory Profile

Cyclo-oxygenase-1 and -2 differently contribute to prostaglandin E2 synthesis and lipid peroxidation after in vivo activation of N-methyl-D-aspartate receptors in rat hippocampus.

Cyclooxygenase-2 is highly expressed in microglial-like cells in a murine model of prion disease

Cyclooxygenase-2, prostaglandin E2, and microglial activation in prion diseases

Deletion of the life span determinant p66Shc prevents age-dependent increases in emotionality and pain sensitivity in mice.

Deletion of the lifespan determinant p66(Shc) improves performance in a spatial memory task, decreases levels of oxidative stress markers in the hippocampus and increases levels of the neurotrophin BDNF in adult mice.

Differential effects of the nonsteroidal antiinflammatory drug flurbiprofen and its nitric oxide-releasing derivative, nitroflurbiprofen, on prostaglandin E(2), interleukin-1beta, and nitric oxide synthesis by activated microglia.

Docosahexaenoic acid modulates inflammatory and antineurogenic functions of activated microglial cells

Docosahexaenoic acid promotes oligodendrocyte differentiation via PPAR-γ signalling and prevents tumor necrosis factor-α-dependent maturational arrest.

Dynamic regulation of microglial functions by the non-steroidal anti-inflammatory drug NCX 2216: implications for chronic treatments of neurodegenerative diseases.

Early-life sex-dependent vulnerability to oxidative stress: the natural twining model.

Effects of the adenosine A2A receptor antagonist SCH 58621 on cyclooxygenase-2 expression, glial activation, and brain-derived neurotrophic factor availability in a rat model of striatal neurodegeneration

Functional characterization of substance P receptors on cultured human spinal cord astrocytes: Synergism of substance P with cytokines in inducing interleukin-6 and prostaglandin E2 production ⬇️

Glycogen synthase kinase 3 is part of the molecular machinery regulating the adaptive response to LPS stimulation in microglial cells.

Greater resistance to inflammation at adulthood could contribute to extended life span of p66(Shc-/-) mice.

Human immunodeficiency virus type-1 Tat protein induces nuclear factor (NF)-kappaB activation and oxidative stress in microglial cultures by independent mechanisms.

In vitro neuronal and glial differentiation from embryonic or adult neural precursor cells are differently affected by chronic or acute activation of microglia.

In vivo activation of N-methyl-D-aspartate receptors in the rat hippocampus increases prostaglandin E(2) extracellular levels and triggers lipid peroxidation through cyclooxygenase-mediated mechanisms.

Increased FUS levels in astrocytes leads to astrocyte and microglia activation and neuronal death

Increased levels of acute-phase inflammatory proteins in plasma of patients with sporadic CJD.

Inducible nitric oxide synthase expression in activated rat microglial cultures is downregulated by exogenous prostaglandin E2 and by cyclooxygenase inhibitors

Interaction between Gut Microbiota and Curcumin: A New Key of Understanding for the Health Effects of Curcumin

Isoprostanes in clinically isolated syndrome and early multiple sclerosis as biomarkers of tissue damage and predictors of clinical course.

Levels of CSF prostaglandin E2, cognitive decline, and survival in Alzheimer's disease.

Maternal immune activation induces autism-like changes in behavior, neuroinflammatory profile and gut microbiota in mouse offspring of both sexes

Microglia in development and disease

Microglial activation in chronic neurodegenerative diseases: roles of apoptotic neurons and chronic stimulation

Microglial polarization and plasticity: evidence from organotypic hippocampal slice cultures.

Minocycline in phenotypic models of Huntington's disease

Modulatory effects following subchronic stimulation of brain 5-HT7-R system in mice and rats.

NGF promotes microglial migration through the activation of its high affinity receptor: modulation by TGF-beta.

Non steroidal anti-inflammatory drugs and neurogenesis in the adult mammalian brain.

Non-Steroidal Anti-Inflammatory Drugs and Brain Inflammation: Effects on Microglial Functions.

Nonenzymatic oxygenated metabolites of α-linolenic acid B1- and L1-phytoprostanes protect immature neurons from oxidant injury and promote differentiation of oligodendrocyte progenitors through PPAR-γ activation

Oxidative stress in twin neonates is influenced by birth weight and weight discordance ⬇️

PPAR-gamma agonists as regulators of microglial activation and brain inflammation.

Paracetamol effectively reduces prostaglandin E2 synthesis in brain macrophages by inhibiting enzymatic activity of cyclooxygenase but not phospholipase and prostaglandin E synthase

Peroxisome proliferator activated receptor-γ agonists protect oligodendrocyte progenitors against tumor necrosis factor-alpha-induced damage: Effects on mitochondrial functions and differentiation.

Peroxisome proliferator-activated receptor γ agonists accelerate oligodendrocyte maturation and influence mitochondrial functions and oscillatory Ca(2+) waves.

Prenatal exposure to the organophosphate insecticide chlorpyrifos enhances brain oxidative stress and prostaglandin E2 synthesis in a mouse model of idiopathic autism

Prolonged exposure of microglia to lipopolysaccharide modifies the intracellular signaling pathways and selectively promotes prostaglandin E2 synthesis.

Prostaglandin E2 and BDNF levels in rat hippocampus are negatively correlated with status epilepticus severity: no impact on survival of seizure-generated neurons.

Prostaglandin E2 synthesis is differentially affected by reactive nitrogen intermediates in cultured rat microglia and RAW 264.7 cells.

Prostaglandin and thromboxane biosynthesis in isolated platelet-free human monocytes. I. A modified procedure for the characterization of the prostaglandin spectrum produced by resting and activated monocytes

Prostaglandin and thromboxane biosynthesis in isolated platelet-free human monocytes. III. The induction of cycloxygenase by colony stimulating factor-1

Purification and partial characterization of serum monocytotropic factor, a platelet-derived cyclooxygenase-inducing polypeptide.

Regulation of Glial Cell Functions by PPAR-gamma Natural and Synthetic Agonists.

Regulation of thromboxane A2 biosynthesis in platelet-free human monocytes and the possible role of polypeptide growth factor(s) in the induction of cyclooxygenase system

Reorientation of prostanoid production accompanies "activation" of adult microglial cells in culture

Restricted cyclooxygenase-2 expression in the central nervous system following acute and delayed-type hypersensitivity responses to bacillus Calmette-Guérin.

Role of neuroinflammation in hypertension-induced brain amyloid pathology

Role of the peroxisome proliferator-activated receptor-gamma (PPAR-gamma) and its natural ligand 15-deoxy-Delta12, 14-prostaglandin J2 in the regulation of microglial functions

Stimulation of adenosine A2A receptors reduces intracellular cholesterol accumulation and rescues mitochondrial abnormalities in human neural cell models of Niemann-Pick C1.

Striatal 6-OHDA lesion in mice: Investigating early neurochemical changes underlying Parkinson's disease

TGF‐β and LPS modulate ADP‐induced migration of microglial cells through P2Y1 and P2Y12 receptor expression ⬇️

Taking pain out of NGF: a "painless" NGF mutant, linked to hereditary sensory autonomic neuropathy type V, with full neurotrophic activity

Targeting CXCR4 by a selective peptide antagonist modulates tumor microenvironment and microglia reactivity in a human glioblastoma model

The mitochondrial uncoupling protein-2 is a master regulator of both M1 and M2 microglial responses.

The nuclear receptor peroxisome proliferator-activated receptor-γ promotes oligodendrocyte differentiation through mechanisms involving mitochondria and oscillatory Ca2+ waves.

The presence of astrocytes enhances beta amyloid-induced neurotoxicity in hippocampal cell cultures.

The stimulation of adenosine A2A receptors ameliorates the pathological phenotype of fibroblasts from Niemann-Pick type C patients.

Transplacental exposure to AZT induces adverse neurochemical and behavioral effects in a mouse model: protection by L-acetylcarnitine

Up-regulation of cyclooxygenase-2 expression in cultured microglia by prostaglandin E2, cyclic AMP and non-steroidal anti-inflammatory drugs

hMTH1 expression protects mitochondria from Huntington's disease-like impairment