Lista de obras - Xuedong Liu - Dominio Público Uruguay

A biosensor for the activity of the "sheddase" TACE (ADAM17) reveals novel and cell type-specific mechanisms of TACE activation

artículo científico publicado en 2015

A chemical genetic approach to probe the function of PINK1 in regulating mitochondrial dynamics.

artículo científico publicado en 2014

A distinct nuclear localization signal in the N terminus of Smad 3 determines its ligand-induced nuclear translocation

artículo científico publicado en 2000

A method of mapping protein sumoylation sites by mass spectrometry using a modified small ubiquitin-like modifier 1 (SUMO-1) and a computational program.

artículo científico publicado en 2005

A negatively charged amino acid in Skp2 is required for Skp2-Cks1 interaction and ubiquitination of p27Kip1

artículo científico publicado en 2003

A transcriptional enhancer from the coding region of ADAMTS5

artículo científico publicado en 2008

Activation of Mps1 promotes transforming growth factor-beta-independent Smad signaling.

artículo científico publicado en 2007

Association of v-ErbA with Smad4 disrupts TGF-beta signaling.

artículo científico publicado en 2009

Axin and GSK3- control Smad3 protein stability and modulate TGF- signaling

artículo científico publicado en 2008

Cellular Abundance of Mps1 and the Role of Its Carboxyl Terminal Tail in Substrate Recruitment ⬇️

artículo científico publicado el 30 de septiembre de 2010

Characterization of the DNA-binding property of Smad5.

artículo científico

Comparative Haploid Genetic Screens Reveal Divergent Pathways in the Biogenesis and Trafficking of Glycophosphatidylinositol-Anchored Proteins.

artículo científico publicado en 2015

Control of cell cycle-dependent degradation of c-Ski proto-oncoprotein by Cdc34.

artículo científico publicado en 2004

Decoding the quantitative nature of TGF-beta/Smad signaling.

artículo científico publicado en 2008

Dynamics of TGF‐β/Smad signaling ⬇️

artículo científico publicado el 9 de abril de 2012

Effects of transmembrane and juxtamembrane domains on proliferative ability of TSLP receptor.

artículo científico publicado en 2010

Estrogen-related receptor alpha 1 functionally binds as a monomer to extended half-site sequences including ones contained within estrogen-response elements

scientific article published on 01 March 1997

Generation of mammalian cells stably expressing multiple genes at predetermined levels.

artículo científico publicado en 2000

Genome-wide analysis of Musashi-2 targets reveals novel functions in governing epithelial cell migration

artículo científico publicado en 2016

Genome-wide dose-dependent inhibition of histone deacetylases studies reveal their roles in enhancer remodeling and suppression of oncogenic super-enhancers.

artículo científico publicado en 2018

High-throughput gateway bicistronic retroviral vectors for stable expression in mammalian cells: exploring the biologic effects of STAT5 overexpression

artículo científico publicado en 2004

High-throughput screening AlphaScreen assay for identification of small-molecule inhibitors of ubiquitin E3 ligase SCFSkp2-Cks1

artículo científico publicado en 2013

Identification and mechanistic studies of a novel ubiquitin E1 inhibitor.

artículo científico publicado en 2012

Importin beta mediates nuclear translocation of Smad 3

artículo científico publicado en 2000

Largazole and its derivatives selectively inhibit ubiquitin activating enzyme (e1)

artículo científico publicado en 2012

Leader cell positioning drives wound-directed collective migration in TGFβ-stimulated epithelial sheets

artículo científico publicado en 2014

Long-term live-cell imaging reveals new roles for Salmonella effector proteins SseG and SteA.

artículo científico publicado en 2016

Measuring TGF-β Ligand Dynamics in Culture Medium

artículo científico publicado en 2016

Measuring the absolute abundance of the Smad transcription factors using quantitative immunoblotting.

artículo científico publicado en 2010

Mechanisms of transforming growth factor beta(1)/Smad signalling mediated by mitogen-activated protein kinase pathways in keloid fibroblasts.

artículo científico publicado en 2009

Modeling keratinocyte wound healing dynamics: Cell-cell adhesion promotes sustained collective migration.

artículo científico publicado en 2016

Multi-Omic Analysis Reveals Disruption of Cholesterol Homeostasis by Cannabidiol in Human Cell Lines

artículo científico publicado en 2022

Negative regulation of SCFSkp2 ubiquitin ligase by TGF-beta signaling.

artículo científico publicado en 2004

Overexpression of Mps1 in colon cancer cells attenuates the spindle assembly checkpoint and increases aneuploidy.

artículo científico publicado en 2014

PINK1 triggers autocatalytic activation of Parkin to specify cell fate decisions

artículo científico publicado en 2014

Partners in crime: the TGFβ and MAPK pathways in cancer progression.

artículo científico publicado en 2011

Pathway- and expression level-dependent effects of oncogenic N-Ras: p27(Kip1) mislocalization by the Ral-GEF pathway and Erk-mediated interference with Smad signaling

artículo científico publicado en 2005

Peroxisome proliferator-activated receptor gamma inhibits transforming growth factor beta-induced connective tissue growth factor expression in human aortic smooth muscle cells by interfering with Smad3

artículo científico publicado en 2001

Post-translational modifications as key regulators of TNF-induced necroptosis

artículo científico publicado en 2016

Quantitative analysis of transient and sustained transforming growth factor-β signaling dynamics.

artículo científico publicado en 2011

Raf kinase inhibitory protein function is regulated via a flexible pocket and novel phosphorylation-dependent mechanism

artículo científico publicado en 2008

Regulation of kinetochore recruitment of two essential mitotic spindle checkpoint proteins by Mps1 phosphorylation

scientific article published on 15 October 2008

Role of glucose metabolism and ATP in maintaining PINK1 levels during Parkin-mediated mitochondrial damage responses.

artículo científico publicado en 2014

Ski/Sno and TGF-beta signaling.

artículo científico publicado en 2001

Structural and mechanistic insights into Mps1 kinase activation

artículo científico publicado en 2009

Structural basis of the phosphorylation-independent recognition of cyclin D1 by the SCFFBXO31 ubiquitin ligase

artículo científico publicado en 2017

Systematic identification of C. elegans miRISC proteins, miRNAs, and mRNA targets by their interactions with GW182 proteins AIN-1 and AIN-2.

artículo científico publicado en 2007

Systems theory of Smad signalling.

artículo científico publicado en 2006

The Anaphase-Promoting Complex Mediates TGF-β Signaling by Targeting SnoN for Destruction ⬇️

artículo científico publicado el 1 de noviembre de 2001

The development of a novel high throughput computational tool for studying individual and collective cellular migration

artículo científico publicado en 2013

The plant triterpenoid celastrol blocks PINK1-dependent mitophagy by disrupting PINK1's association with the mitochondrial protein TOM20

artículo científico publicado en 2019

Transforming growth factor beta depletion is the primary determinant of Smad signaling kinetics

scientific article published on 17 February 2009

Transforming growth factor β-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells ⬇️

artículo científico publicado el 30 de septiembre de 1997

Transforming growth factor-beta induces formation of a dithiothreitol-resistant type I/Type II receptor complex in live cells.

artículo científico publicado en 1999

Two LXXLL motifs in the N terminus of Mps1 are required for Mps1 nuclear import during G(2)/M transition and sustained spindle checkpoint responses.

artículo científico publicado en 2011

Ubc9 expression is essential for myotube formation in C2C12

artículo científico publicado en 2006

Ubiquitination of p21Cip1/WAF1 by SCFSkp2: substrate requirement and ubiquitination site selection.

artículo científico publicado en 2005

Ubiquitination of p27Kip1 requires physical interaction with cyclin E and probable phosphate recognition by SKP2.

artículo científico publicado en 2005

Unraveling transcriptional control and cis-regulatory codes using the software suite GeneACT.

artículo científico publicado en 2006

Lista de obras de Xuedong Liu

A biosensor for the activity of the "sheddase" TACE (ADAM17) reveals novel and cell type-specific mechanisms of TACE activation

A chemical genetic approach to probe the function of PINK1 in regulating mitochondrial dynamics.

A distinct nuclear localization signal in the N terminus of Smad 3 determines its ligand-induced nuclear translocation

A method of mapping protein sumoylation sites by mass spectrometry using a modified small ubiquitin-like modifier 1 (SUMO-1) and a computational program.

A negatively charged amino acid in Skp2 is required for Skp2-Cks1 interaction and ubiquitination of p27Kip1

A transcriptional enhancer from the coding region of ADAMTS5

Activation of Mps1 promotes transforming growth factor-beta-independent Smad signaling.

Association of v-ErbA with Smad4 disrupts TGF-beta signaling.

Axin and GSK3- control Smad3 protein stability and modulate TGF- signaling

Cellular Abundance of Mps1 and the Role of Its Carboxyl Terminal Tail in Substrate Recruitment ⬇️

Characterization of the DNA-binding property of Smad5.

Comparative Haploid Genetic Screens Reveal Divergent Pathways in the Biogenesis and Trafficking of Glycophosphatidylinositol-Anchored Proteins.

Control of cell cycle-dependent degradation of c-Ski proto-oncoprotein by Cdc34.

Decoding the quantitative nature of TGF-beta/Smad signaling.

Dynamics of TGF‐β/Smad signaling ⬇️

Effects of transmembrane and juxtamembrane domains on proliferative ability of TSLP receptor.

Estrogen-related receptor alpha 1 functionally binds as a monomer to extended half-site sequences including ones contained within estrogen-response elements

Generation of mammalian cells stably expressing multiple genes at predetermined levels.

Genome-wide analysis of Musashi-2 targets reveals novel functions in governing epithelial cell migration

Genome-wide dose-dependent inhibition of histone deacetylases studies reveal their roles in enhancer remodeling and suppression of oncogenic super-enhancers.

High-throughput gateway bicistronic retroviral vectors for stable expression in mammalian cells: exploring the biologic effects of STAT5 overexpression

High-throughput screening AlphaScreen assay for identification of small-molecule inhibitors of ubiquitin E3 ligase SCFSkp2-Cks1

Identification and mechanistic studies of a novel ubiquitin E1 inhibitor.

Importin beta mediates nuclear translocation of Smad 3

Largazole and its derivatives selectively inhibit ubiquitin activating enzyme (e1)

Leader cell positioning drives wound-directed collective migration in TGFβ-stimulated epithelial sheets

Long-term live-cell imaging reveals new roles for Salmonella effector proteins SseG and SteA.

Measuring TGF-β Ligand Dynamics in Culture Medium

Measuring the absolute abundance of the Smad transcription factors using quantitative immunoblotting.

Mechanisms of transforming growth factor beta(1)/Smad signalling mediated by mitogen-activated protein kinase pathways in keloid fibroblasts.

Modeling keratinocyte wound healing dynamics: Cell-cell adhesion promotes sustained collective migration.

Multi-Omic Analysis Reveals Disruption of Cholesterol Homeostasis by Cannabidiol in Human Cell Lines

Negative regulation of SCFSkp2 ubiquitin ligase by TGF-beta signaling.

Overexpression of Mps1 in colon cancer cells attenuates the spindle assembly checkpoint and increases aneuploidy.

PINK1 triggers autocatalytic activation of Parkin to specify cell fate decisions

Partners in crime: the TGFβ and MAPK pathways in cancer progression.

Pathway- and expression level-dependent effects of oncogenic N-Ras: p27(Kip1) mislocalization by the Ral-GEF pathway and Erk-mediated interference with Smad signaling

Peroxisome proliferator-activated receptor gamma inhibits transforming growth factor beta-induced connective tissue growth factor expression in human aortic smooth muscle cells by interfering with Smad3

Post-translational modifications as key regulators of TNF-induced necroptosis

Quantitative analysis of transient and sustained transforming growth factor-β signaling dynamics.

Raf kinase inhibitory protein function is regulated via a flexible pocket and novel phosphorylation-dependent mechanism

Regulation of kinetochore recruitment of two essential mitotic spindle checkpoint proteins by Mps1 phosphorylation

Role of glucose metabolism and ATP in maintaining PINK1 levels during Parkin-mediated mitochondrial damage responses.

Ski/Sno and TGF-beta signaling.

Structural and mechanistic insights into Mps1 kinase activation

Structural basis of the phosphorylation-independent recognition of cyclin D1 by the SCFFBXO31 ubiquitin ligase

Systematic identification of C. elegans miRISC proteins, miRNAs, and mRNA targets by their interactions with GW182 proteins AIN-1 and AIN-2.

Systems theory of Smad signalling.

The Anaphase-Promoting Complex Mediates TGF-β Signaling by Targeting SnoN for Destruction ⬇️

The development of a novel high throughput computational tool for studying individual and collective cellular migration

The plant triterpenoid celastrol blocks PINK1-dependent mitophagy by disrupting PINK1's association with the mitochondrial protein TOM20

Transforming growth factor beta depletion is the primary determinant of Smad signaling kinetics

Transforming growth factor β-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells ⬇️

Transforming growth factor-beta induces formation of a dithiothreitol-resistant type I/Type II receptor complex in live cells.

Two LXXLL motifs in the N terminus of Mps1 are required for Mps1 nuclear import during G(2)/M transition and sustained spindle checkpoint responses.

Ubc9 expression is essential for myotube formation in C2C12

Ubiquitination of p21Cip1/WAF1 by SCFSkp2: substrate requirement and ubiquitination site selection.

Ubiquitination of p27Kip1 requires physical interaction with cyclin E and probable phosphate recognition by SKP2.

Unraveling transcriptional control and cis-regulatory codes using the software suite GeneACT.