Filtros de búsqueda

Lista de obras de Christina F Spiropoulou

25-Hydroxycholesterol Inhibition of Lassa Virus Infection through Aberrant GP1 Glycosylation

artículo científico publicado en 2016

4'-Azidocytidine (R1479) inhibits henipaviruses and other paramyxoviruses with high potency

artículo científico

646. Activated Macrophages as Pathogenesis Factors in Ebola Virus Disease in Humans

A Case of Human Lassa Virus Infection With Robust Acute T-Cell Activation and Long-Term Virus-Specific T-Cell Responses

artículo científico publicado en 2017

A Conserved Basic Patch and Central Kink in the Nipah Virus Phosphoprotein Multimerization Domain Are Essential for Polymerase Function

artículo científico publicado en 2019

A Molecular Sensor To Characterize Arenavirus Envelope Glycoprotein Cleavage by Subtilisin Kexin Isozyme 1/Site 1 Protease

artículo científico publicado en 2015

A chronological review of experimental infection studies of the role of wild animals and livestock in the maintenance and transmission of Crimean-Congo hemorrhagic fever virus

artículo científico publicado en 2016

A genome-wide CRISPR screen identifies N-acetylglucosamine-1-phosphate transferase as a potential antiviral target for Ebola virus

scientific article published in Nature Communications

A single mutation in Crimean-Congo hemorrhagic fever virus discovered in ticks impairs infectivity in human cells

artículo científico publicado en 2020

Activation and cell death in human dendritic cells infected with Nipah virus

artículo científico publicado en 2013

Adaptive immune responses in humans during Nipah virus acute and convalescent phases of infection

article

Alterations in Blood Chemistry Levels Associated With Nipah Virus Disease in the Syrian Hamster Model

scientific article published on 20 November 2019

Andes and Prospect Hill hantaviruses differ in early induction of interferon although both can downregulate interferon signaling

artículo científico publicado en 2007

Andes virus disrupts the endothelial cell barrier by induction of vascular endothelial growth factor and downregulation of VE-cadherin

artículo científico publicado en 2010

Antibodies Against Henipa-Like Viruses in Brazilian Bats

artículo científico publicado en 2017

Assessment of Inhibitors of Pathogenic Crimean-Congo Hemorrhagic Fever Virus Strains Using Virus-Like Particles

artículo científico publicado en 2015

Biomarker correlates of survival in pediatric patients with Ebola virus disease

artículo científico publicado en 2014

Biomarkers for understanding Ebola virus disease

artículo científico publicado en 2014

Broad-spectrum Investigational Agent GS-5734 for the Treatment of Ebola, MERS Coronavirus and Other Pathogenic Viral Infections with High Outbreak Potential.

artículo científico publicado en 2017

CD4 T cells, CD8 T cells, and monocytes coordinate to prevent Rift Valley fever virus encephalitis

artículo científico publicado en 2018

Characterisation of infectious Ebola virus from the ongoing outbreak to guide response activities in the Democratic Republic of the Congo: a phylogenetic and in vitro analysis

artículo científico publicado en 2019

Characterization of the cellular receptors for the South American hemorrhagic fever viruses Junin, Guanarito, and Machupo.

artículo científico publicado en 2006

Characterization of the interaction of lassa fever virus with its cellular receptor alpha-dystroglycan

artículo científico publicado en 2005

Clinical care of two patients with Ebola virus disease in the United States

artículo científico publicado en 2014

Corrigendum to: In Situ Imaging of Fluorescent Nipah Virus Respiratory and Neurological Tissue Tropism in the Syrian Hamster Model

artículo científico publicado en 2019

Crimean-Congo Hemorrhagic Fever Virus Suppresses Innate Immune Responses via a Ubiquitin and ISG15 Specific Protease.

artículo científico publicado en 2017

Crimean-Congo Hemorrhagic Fever in Humanized Mice Reveals Glial Cells as Primary Targets of Neurological Infection

artículo científico

Crimean-Congo hemorrhagic fever and expansion from endemic regions

artículo científico publicado en 2019

Defining antigen-specific plasmablast and memory B cell subsets in human blood after viral infection or vaccination

artículo científico publicado en 2016

Development of a reverse genetics system for Sosuga virus allows rapid screening of antiviral compounds.

artículo científico publicado en 2018

Distinct and overlapping roles of Nipah virus P gene products in modulating the human endothelial cell antiviral response

artículo científico publicado en 2012

Ebola Virus Diagnostics: The US Centers for Disease Control and Prevention Laboratory in Sierra Leone, August 2014 to March 2015.

artículo científico publicado en 2015

Ebola Virus Disease Diagnostics, Sierra Leone: Analysis of Real-time Reverse Transcription-Polymerase Chain Reaction Values for Clinical Blood and Oral Swab Specimens

artículo científico publicado en 2016

Ebola Virus Persistence in Semen of Male Survivors

artículo científico publicado en 2016

Ebola Virus Replication and Disease Without Immunopathology in Mice Expressing Transgenes to Support Human Myeloid and Lymphoid Cell Engraftment

artículo científico publicado en 2016

Ebola hemorrhagic Fever: novel biomarker correlates of clinical outcome

artículo científico publicado en 2014

Ebola virus infection of human PBMCs causes massive death of macrophages, CD4 and CD8 T cell sub-populations in vitro.

artículo científico publicado en 2007

Effect of Vandetanib on Andes virus survival in the hamster model of Hantavirus pulmonary syndrome

artículo científico publicado en 2016

Endocytic Pathways Used by Andes Virus to Enter Primary Human Lung Endothelial Cells

artículo científico publicado en 2016

Evaluation of a Single-Dose Nucleoside-Modified Messenger RNA Vaccine Encoding Hendra Virus-Soluble Glycoprotein Against Lethal Nipah virus Challenge in Syrian Hamsters

artículo científico publicado en 2019

Evaluation of luciferase and GFP-expressing Nipah viruses for rapid quantitative antiviral screening

artículo científico publicado en 2014

Evaluation of the Activity of Lamivudine and Zidovudine against Ebola Virus

artículo científico publicado en 2016

Flex-nucleoside analogues - Novel therapeutics against filoviruses

artículo científico publicado en 2017

Fluorescent Crimean-Congo hemorrhagic fever virus illuminates tissue tropism patterns and identifies early mononuclear phagocytic cell targets in Ifnar-/- mice

scientific article published on 02 December 2019

GS-5734 and its parent nucleoside analog inhibit Filo-, Pneumo-, and Paramyxoviruses

artículo científico publicado en 2017

Genome Sequences of Crimean-Congo Hemorrhagic Fever Virus Strains Isolated in South Africa, Namibia, and Turkey

artículo científico publicado en 2017

Griffithsin Inhibits Nipah Virus Entry and Fusion and Can Protect Syrian Golden Hamsters From Lethal Nipah Virus Challenge

scientific article published on 10 February 2020

Hantavirus Infection Is Inhibited by Griffithsin in Cell Culture

artículo científico publicado en 2020

Hantavirus pulmonary syndrome

artículo científico publicado en 2011

Heterologous protection against Crimean-Congo hemorrhagic fever in mice after a single dose of replicon particle vaccine

scientific article published on 01 August 2019

Host mTORC1 signaling regulates andes virus replication

artículo científico publicado en 2012

Host-Species Transferrin Receptor 1 Orthologs Are Cellular Receptors for Nonpathogenic New World Clade B Arenaviruses

artículo científico publicado en 2009

Human Biomarkers of Outcome following Rift Valley fever virus Infection

artículo científico publicado en 2018

Human Ebola virus infection results in substantial immune activation

artículo científico publicado en 2015

Human immune cell engraftment does not alter development of severe acute Rift Valley fever in mice

artículo científico publicado en 2018

Human immune system mouse models of Ebola virus infection.

artículo científico

Humanized Mouse Model of Ebola Virus Disease Mimics the Immune Responses in Human Disease

artículo científico publicado en 2015

Identification of 2'-deoxy-2'-fluorocytidine as a potent inhibitor of Crimean-Congo hemorrhagic fever virus replication using a recombinant fluorescent reporter virus

artículo científico publicado en 2017

Identification of broadly neutralizing monoclonal antibodies against Crimean-Congo hemorrhagic fever virus

artículo científico

Immunologic timeline of Ebola virus disease and recovery in humans

scientific article published on 21 May 2020

In Situ Imaging of Fluorescent Nipah Virus Respiratory and Neurological Tissue Tropism in the Syrian Hamster Model

scientific article published on 30 October 2019

Inference of Nipah virus evolution, 1999–2015

scientific article published on 13 August 2020

Inhibition of Nipah Virus by Defective Interfering Particles

scientific article published on 28 February 2020

Inhibitors of cellular kinases with broad-spectrum antiviral activity for hemorrhagic fever viruses

artículo científico publicado en 2015

Inhibitors of the tick-borne, hemorrhagic fever-associated flaviviruses.

artículo científico publicado en 2014

Initiation, extension, and termination of RNA synthesis by a paramyxovirus polymerase.

artículo científico publicado en 2018

In vitro antiviral activity of adenosine analog NITD008 against tick-borne flaviviruses

artículo científico publicado en 2016

Kinetic Analysis of Biomarkers in a Cohort of US Patients With Ebola Virus Disease

artículo científico publicado en 2016

Kyasanur Forest disease virus infection in mice is associated with higher morbidity and mortality than infection with the closely related Alkhurma hemorrhagic fever virus

artículo científico publicado en 2014

Laboratory Response to Ebola - West Africa and United States

artículo científico

Lassa Virus Targeting of Anterior Uvea and Endothelium of Cornea and Conjunctiva in Eye of Guinea Pig Model

scholarly article by Joy M Gary et al published May 2019 in Emerging Infectious Diseases

Lassa and Ebola virus inhibitors identified using minigenome and recombinant virus reporter systems.

artículo científico

Lassa virus antigen distribution and inflammation in the ear of infected strain 13/N guinea pigs

artículo científico publicado en 2020

Longitudinal Analysis of the Human B Cell Response to Ebola Virus Infection

artículo científico publicado en 2019

Macrophage Activation Marker Soluble CD163 Associated with Fatal and Severe Ebola Virus Disease in Humans

scientific article published in 2019

Molecular Insights into Crimean-Congo Hemorrhagic Fever Virus

artículo científico publicado en 2016

New World arenavirus clade C, but not clade A and B viruses, utilizes alpha-dystroglycan as its major receptor

artículo científico publicado en 2002

Nipah virus outbreaks: still small but extremely lethal

scientific article published on 01 May 2019

Novel paramyxovirus associated with severe acute febrile disease, South Sudan and Uganda, 2012

artículo científico publicado en 2014

Old World and clade C New World arenaviruses mimic the molecular mechanism of receptor recognition used by alpha-dystroglycan's host-derived ligands

artículo científico publicado en 2007

Personal protective equipment for filovirus epidemics: a call for better evidence

artículo científico publicado en 2015

Posttranslational modification of alpha-dystroglycan, the cellular receptor for arenaviruses, by the glycosyltransferase LARGE is critical for virus binding.

artículo científico publicado en 2005

Potent in vitro activity of β-D-4'-chloromethyl-2'-deoxy-2'-fluorocytidine against Nipah virus

scientific article published on 11 January 2020

Probing the Effects of Pyrimidine Functional Group Switches on Acyclic Fleximer Analogues for Antiviral Activity

scientific article published on 02 September 2019

Protection From Lethal Lassa Disease Can Be Achieved Both Before and After Virus Exposure by Administration of Single-Cycle Replicating Lassa Virus Replicon Particles

scientific article published on 01 September 2019

RIG-I Mediates an Antiviral Response to Crimean-Congo Hemorrhagic Fever Virus

artículo científico publicado en 2015

RIG-I activation inhibits ebolavirus replication

artículo científico publicado en 2009

Rapid determination of ebolavirus infectivity in clinical samples using a novel reporter cell line

artículo científico publicado en 2017

Rapid diagnosis of Ebola hemorrhagic fever by reverse transcription-PCR in an outbreak setting and assessment of patient viral load as a predictor of outcome

scientific article published on April 2004

Receptor determinants of zoonotic transmission of New World hemorrhagic fever arenaviruses

artículo científico publicado en 2008

Recovery of Recombinant Crimean Congo Hemorrhagic Fever Virus Reveals a Function for Non-structural Glycoproteins Cleavage by Furin

artículo científico publicado en 2015

Reduced virus replication, proinflammatory cytokine production, and delayed macrophage cell death in human PBMCs infected with the newly discovered Bundibugyo ebolavirus relative to Zaire ebolavirus

artículo científico publicado en 2010

Relationship Between Ebola Virus Real-Time Quantitative Polymerase Chain Reaction-Based Threshold Cycle Value and Virus Isolation From Human Plasma

artículo científico publicado en 2015

Remdesivir (GS-5734) protects African green monkeys from Nipah virus challenge

artículo científico publicado en 2019

Remdesivir targets a structurally analogous region of the Ebola virus and SARS-CoV-2 polymerases

artículo científico publicado en 2020

Reply to Fedson

artículo científico publicado en 2014

Reverse genetics recovery of Lujo virus and role of virus RNA secondary structures in efficient virus growth

artículo científico publicado en 2012

Rift Valley fever virus clearance and protection from neurologic disease are dependent on CD4+ T cell and virus-specific antibody responses

artículo científico publicado en 2013

Rift Valley fever virus vaccination induces long-lived, antigen-specific human T cell responses

artículo científico publicado en 2020

Rift Valley fever virus vaccine lacking the NSs and NSm genes is safe, nonteratogenic, and confers protection from viremia, pyrexia, and abortion following challenge in adult and pregnant sheep

artículo científico publicado en 2011

Rift valley Fever virus encephalitis is associated with an ineffective systemic immune response and activated T cell infiltration into the CNS in an immunocompetent mouse model

artículo científico publicado en 2014

Rift valley fever viral load correlates with the human inflammatory response and coagulation pathway abnormalities in humans with hemorrhagic manifestations.

artículo científico publicado en 2018

Serology and cytokine profiles in patients infected with the newly discovered Bundibugyo ebolavirus

artículo científico publicado en 2011

Severe hemorrhagic fever in strain 13/N guinea pigs infected with Lujo virus

artículo científico publicado en 2012

Severity of Disease in Humanized Mice Infected with Ebola Virus or Reston Virus is Associated with Magnitude of Early Viral Replication in Liver

artículo científico publicado en 2017

Single-dose replication-defective VSV-based Nipah virus vaccines provide protection from lethal challenge in Syrian hamsters

artículo científico publicado en 2013

Single-dose replicon particle vaccine provides complete protection against Crimean-Congo hemorrhagic fever virus in mice

artículo científico publicado en 2019

Site 1 protease is required for proteolytic processing of the glycoproteins of the South American hemorrhagic fever viruses Junin, Machupo, and Guanarito

artículo científico publicado en 2008

Small interfering RNA inhibition of Andes virus replication

artículo científico publicado en 2014

Stable Occupancy of the Crimean-Congo Hemorrhagic Fever Virus-Encoded Deubiquitinase Blocks Viral Infection

artículo científico publicado en 2019

Statins Suppress Ebola Virus Infectivity by Interfering with Glycoprotein Processing.

artículo científico publicado en 2018

Suboptimal Handling of Piccolo Samples or Reagent Discs for Consideration in Ebola Response

artículo científico publicado en 2019

Susceptibility of paramyxoviruses and filoviruses to inhibition by 2'-monofluoro- and 2'-difluoro-4'-azidocytidine analogs.

artículo científico publicado en 2018

The Crimean-Congo Hemorrhagic Fever Virus NSm Protein is Dispensable for Growth In Vitro and Disease in Ifnar-/- Mice

scientific article published on 21 May 2020

The S Genome Segment Is Sufficient to Maintain Pathogenicity in Intra-Clade Lassa Virus Reassortants in a Guinea Pig Model

artículo científico publicado en 2018

The Use of TKM-100802 and Convalescent Plasma in 2 Patients With Ebola Virus Disease in the United States

artículo científico publicado en 2015

The lipid moiety of brincidofovir is required for in vitro antiviral activity against Ebola virus

artículo científico publicado en 2015

The role of endothelial activation in dengue hemorrhagic fever and hantavirus pulmonary syndrome

artículo científico publicado en 2013

The use of mice lacking type I or both type I and type II interferon responses in research on hemorrhagic fever viruses. Part 2: Vaccine efficacy studies

scientific article published on 22 January 2020

Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys

artículo científico publicado en 2016

Towards a Sustainable One Health Approach to Crimean-Congo Hemorrhagic Fever Prevention: Focus Areas and Gaps in Knowledge

scientific article published on 07 July 2020

Transferrin receptor 1 is a cellular receptor for New World haemorrhagic fever arenaviruses

artículo científico publicado en 2007

Twenty Years of Nipah Virus Research: Where Do We Go From Here?

artículo científico publicado en 2020

Unique small molecule entry inhibitors of hemorrhagic fever arenaviruses

artículo científico publicado en 2008

Use of a Scalable Replicon-Particle Vaccine to Protect Against Lethal Lassa Virus Infection in the Guinea Pig Model

artículo científico publicado en 2018

Use of monoclonal antibodies against Hendra and Nipah viruses in an antigen capture ELISA

artículo científico publicado en 2010

Utility of Oral Swab Sampling for Ebola Virus Detection in Guinea Pig Model

artículo científico publicado en 2015

Vascular events in viral hemorrhagic fevers: a comparative study of dengue and hantaviruses

artículo científico publicado en 2014

Von Willebrand factor is elevated in individuals infected with Sudan virus and is associated with adverse clinical outcomes

artículo científico publicado en 2015

Whole Blood-Based Multiplex Immunoassays for the Evaluation of Human Biomarker Responses to Emerging Viruses in Resource-Limited Regions

artículo científico publicado en 2017

Dominio Público Uruguay está sostenido por:

Acerca de Dominio Público Uruguay

Ayuda