Lista de obras - Ornella Rossetto - Dominio Público Uruguay

Active-site mutagenesis of tetanus neurotoxin implicates TYR-375 and GLU-271 in metalloproteolytic activity

artículo científico publicado en 2001

Alternative splicing of the human gene SYBL1 modulates protein domain architecture of Longin VAMP7/TI-VAMP, showing both non-SNARE and synaptobrevin-like isoforms

artículo científico publicado en 2011

Antiepileptic effects of botulinum neurotoxin E.

artículo científico publicado en 2005

Arg206 of SNAP-25 is essential for neuroexocytosis at the Drosophila melanogaster neuromuscular junction

artículo científico publicado en 2010

Assay of diffusion of different botulinum neurotoxin type a formulations injected in the mouse leg

artículo científico publicado en 2009

Bacterial toxins with intracellular protease activity.

artículo científico publicado en 2000

Botulinum neurotoxin C mutants reveal different effects of syntaxin or SNAP-25 proteolysis on neuromuscular transmission.

artículo científico publicado en 2017

Botulinum neurotoxin serotype D is poorly effective in humans: an in vivo electrophysiological study.

artículo científico publicado en 2012

Botulinum neurotoxin serotypes A and C do not affect motor units survival in humans: an electrophysiological study by motor units counting.

artículo científico publicado en 2002

Botulinum neurotoxin type A is internalized and translocated from small synaptic vesicles at the neuromuscular junction.

artículo científico publicado en 2013

Botulinum neurotoxins ⬇️

artículo científico publicado el 19 de febrero de 2013

Botulinum neurotoxins A and E undergo retrograde axonal transport in primary motor neurons

artículo científico publicado en 2012

Botulinum neurotoxins and formalin-induced pain: central vs. peripheral effects in mice

artículo científico publicado en 2006

Botulinum neurotoxins: genetic, structural and mechanistic insights.

artículo científico

Botulinum toxin type A selectivity for certain types of pain is associated with capsaicin-sensitive neurons

artículo científico publicado en 2014

Calcium Influx and Mitochondrial Alterations at Synapses Exposed to Snake Neurotoxins or Their Phospholipid Hydrolysis Products

artículo científico publicado en 2007

Calcium imaging of muscle cells treated with snake myotoxins reveals toxin synergism and presence of acceptors.

artículo científico publicado en 2009

Calcium overload in nerve terminals of cultured neurons intoxicated by alpha-latrotoxin and snake PLA2 neurotoxins

artículo científico publicado en 2009

Clinical use of non-A botulinum toxins: botulinum toxin type C and botulinum toxin type F

artículo científico publicado en 2006

Common and distinct fusion proteins in axonal growth and transmitter release

artículo científico publicado en 1996

Comparison of the pH-induced conformational change of different clostridial neurotoxins.

artículo científico publicado en 2004

Different mechanism of blockade of neuroexocytosis by presynaptic neurotoxins.

artículo científico publicado en 2004

Different time courses of recovery after poisoning with botulinum neurotoxin serotypes A and E in humans.

artículo científico publicado en 1998

Double anchorage to the membrane and intact inter-chain disulfide bond are required for the low pH induced entry of tetanus and botulinum neurotoxins into neurons.

artículo científico publicado en 2011

Electrophysiological Characterization of the Antarease Metalloprotease from Tityus serrulatus Venom. ⬇️

artículo científico publicado en 2017

Entering neurons: botulinum toxins and synaptic vesicle recycling

artículo científico publicado en 2006

Equivalent effects of snake PLA2 neurotoxins and lysophospholipid-fatty acid mixtures

artículo científico publicado en 2005

Evidence for a radial SNARE super-complex mediating neurotransmitter release at the Drosophila neuromuscular junction.

artículo científico publicado en 2013

Evidence for anterograde transport and transcytosis of botulinum neurotoxin A (BoNT/A).

artículo científico publicado en 2011

Glycogen synthase kinase 3 activation is essential for the snake phospholipase A2 neurotoxin-induced secretion in chromaffin cells

High Conservation of Tetanus and Botulinum Neurotoxins Cleavage Sites on Human SNARE Proteins Suggests That These Pathogens Exerted Little or No Evolutionary Pressure on Humans

artículo científico publicado en 2017

How do presynaptic PLA2 neurotoxins block nerve terminals?

scientific article published on 01 June 2000

Internalization and proteolytic action of botulinum toxins in CNS neurons and astrocytes.

artículo científico publicado en 1999

Long-distance retrograde effects of botulinum neurotoxin A

scientific article published on 01 April 2008

Mass spectrometry analysis of the phospholipase A(2) activity of snake pre-synaptic neurotoxins in cultured neurons.

artículo científico publicado en 2009

Neuromuscular paralysis and recovery in mice injected with botulinum neurotoxins A and C

artículo científico publicado en 2007

Neurotoxicity of European viperids in Italy: Pavia Poison Control Centre case series 2001-2011.

artículo científico publicado en 2014

Neutralisation of specific surface carboxylates speeds up translocation of botulinum neurotoxin type B enzymatic domain.

artículo científico publicado en 2013

On the action of botulinum neurotoxins A and E at cholinergic terminals

artículo científico publicado en 1998

Presynaptic enzymatic neurotoxins.

artículo científico publicado en 2006

Presynaptic receptor arrays for clostridial neurotoxins.

artículo científico publicado en 2004

Re-assembled botulinum neurotoxin inhibits CNS functions without systemic toxicity

artículo científico publicado en 2011

Reversible skeletal neuromuscular paralysis induced by different lysophospholipids

artículo científico publicado en 2006

SNARE motif and neurotoxins

artículo científico publicado en 1994

Site-Directed Mutagenesis Identifies Active-Site Residues of the Light Chain of Botulinum Neurotoxin Type A ⬇️

artículo científico publicado el 16 de noviembre de 2001

Snake presynaptic neurotoxins with phospholipase A2 activity induce punctate swellings of neurites and exocytosis of synaptic vesicles

artículo científico publicado en 2004

Structural determinants of the specificity for synaptic vesicle-associated membrane protein/synaptobrevin of tetanus and botulinum type B and G neurotoxins

scientific article published on 01 August 1996

Substrate residues N-terminal to the cleavage site of botulinum type B neurotoxin play a role in determining the specificity of its endopeptidase activity

scientific article published on 01 May 1996

Tetanus neurotoxin-induced epilepsy in mouse visual cortex.

artículo científico publicado en 2012

Tetanus neurotoxin.

artículo científico

Tetanus toxin receptor. Specific cross-linking of tetanus toxin to a protein of NGF-differentiated PC 12 cells.

artículo científico publicado en 1991

Tetanus toxin-sensitive VAMP-related proteins are present in murine macrophages.

artículo científico publicado en 1996

The N-terminal half of the receptor domain of botulinum neurotoxin A binds to microdomains of the plasma membrane

artículo científico publicado en 2009

The metallo-proteinase activity of tetanus and botulism neurotoxins ⬇️

artículo científico publicado el 1 de enero de 1995

The thioredoxin reductase-thioredoxin system is involved in the entry of tetanus and botulinum neurotoxins in the cytosol of nerve terminals.

artículo científico publicado en 2012

Thioredoxin and its reductase are present on synaptic vesicles, and their inhibition prevents the paralysis induced by botulinum neurotoxins.

artículo científico publicado en 2014

Time course and temperature dependence of the membrane translocation of tetanus and botulinum neurotoxins C and D in neurons ⬇️

artículo científico publicado el 27 de noviembre de 2012

Toxicity of botulinum neurotoxins in central nervous system of mice

artículo científico publicado en 2003

Traffic of botulinum toxins A and E in excitatory and inhibitory neurons.

artículo científico publicado en 2007

Transient synaptic silencing of developing striate cortex has persistent effects on visual function and plasticity

artículo científico publicado en 2007

VAMP/synaptobrevin cleavage by tetanus and botulinum neurotoxins is strongly enhanced by acidic liposomes

scientific article published on 01 May 2003

Vesicle-associated membrane protein (VAMP)/synaptobrevin-2 is associated with dense core secretory granules in PC12 neuroendocrine cells.

artículo científico publicado en 1995

Lista de obras de Ornella Rossetto

Active-site mutagenesis of tetanus neurotoxin implicates TYR-375 and GLU-271 in metalloproteolytic activity

Alternative splicing of the human gene SYBL1 modulates protein domain architecture of Longin VAMP7/TI-VAMP, showing both non-SNARE and synaptobrevin-like isoforms

Antiepileptic effects of botulinum neurotoxin E.

Arg206 of SNAP-25 is essential for neuroexocytosis at the Drosophila melanogaster neuromuscular junction

Assay of diffusion of different botulinum neurotoxin type a formulations injected in the mouse leg

Bacterial toxins with intracellular protease activity.

Botulinum neurotoxin C mutants reveal different effects of syntaxin or SNAP-25 proteolysis on neuromuscular transmission.

Botulinum neurotoxin serotype D is poorly effective in humans: an in vivo electrophysiological study.

Botulinum neurotoxin serotypes A and C do not affect motor units survival in humans: an electrophysiological study by motor units counting.

Botulinum neurotoxin type A is internalized and translocated from small synaptic vesicles at the neuromuscular junction.

Botulinum neurotoxins ⬇️

Botulinum neurotoxins A and E undergo retrograde axonal transport in primary motor neurons

Botulinum neurotoxins and formalin-induced pain: central vs. peripheral effects in mice

Botulinum neurotoxins: genetic, structural and mechanistic insights.

Botulinum toxin type A selectivity for certain types of pain is associated with capsaicin-sensitive neurons

Calcium Influx and Mitochondrial Alterations at Synapses Exposed to Snake Neurotoxins or Their Phospholipid Hydrolysis Products

Calcium imaging of muscle cells treated with snake myotoxins reveals toxin synergism and presence of acceptors.

Calcium overload in nerve terminals of cultured neurons intoxicated by alpha-latrotoxin and snake PLA2 neurotoxins

Clinical use of non-A botulinum toxins: botulinum toxin type C and botulinum toxin type F

Common and distinct fusion proteins in axonal growth and transmitter release

Comparison of the pH-induced conformational change of different clostridial neurotoxins.

Different mechanism of blockade of neuroexocytosis by presynaptic neurotoxins.

Different time courses of recovery after poisoning with botulinum neurotoxin serotypes A and E in humans.

Double anchorage to the membrane and intact inter-chain disulfide bond are required for the low pH induced entry of tetanus and botulinum neurotoxins into neurons.

Electrophysiological Characterization of the Antarease Metalloprotease from Tityus serrulatus Venom. ⬇️

Entering neurons: botulinum toxins and synaptic vesicle recycling

Equivalent effects of snake PLA2 neurotoxins and lysophospholipid-fatty acid mixtures

Evidence for a radial SNARE super-complex mediating neurotransmitter release at the Drosophila neuromuscular junction.

Evidence for anterograde transport and transcytosis of botulinum neurotoxin A (BoNT/A).

Glycogen synthase kinase 3 activation is essential for the snake phospholipase A2 neurotoxin-induced secretion in chromaffin cells

High Conservation of Tetanus and Botulinum Neurotoxins Cleavage Sites on Human SNARE Proteins Suggests That These Pathogens Exerted Little or No Evolutionary Pressure on Humans

How do presynaptic PLA2 neurotoxins block nerve terminals?

Internalization and proteolytic action of botulinum toxins in CNS neurons and astrocytes.

Long-distance retrograde effects of botulinum neurotoxin A

Mass spectrometry analysis of the phospholipase A(2) activity of snake pre-synaptic neurotoxins in cultured neurons.

Neuromuscular paralysis and recovery in mice injected with botulinum neurotoxins A and C

Neurotoxicity of European viperids in Italy: Pavia Poison Control Centre case series 2001-2011.

Neutralisation of specific surface carboxylates speeds up translocation of botulinum neurotoxin type B enzymatic domain.

On the action of botulinum neurotoxins A and E at cholinergic terminals

Presynaptic enzymatic neurotoxins.

Presynaptic receptor arrays for clostridial neurotoxins.

Re-assembled botulinum neurotoxin inhibits CNS functions without systemic toxicity

Reversible skeletal neuromuscular paralysis induced by different lysophospholipids

SNARE motif and neurotoxins

Site-Directed Mutagenesis Identifies Active-Site Residues of the Light Chain of Botulinum Neurotoxin Type A ⬇️

Snake presynaptic neurotoxins with phospholipase A2 activity induce punctate swellings of neurites and exocytosis of synaptic vesicles

Structural determinants of the specificity for synaptic vesicle-associated membrane protein/synaptobrevin of tetanus and botulinum type B and G neurotoxins

Substrate residues N-terminal to the cleavage site of botulinum type B neurotoxin play a role in determining the specificity of its endopeptidase activity

Tetanus neurotoxin-induced epilepsy in mouse visual cortex.

Tetanus neurotoxin.

Tetanus toxin receptor. Specific cross-linking of tetanus toxin to a protein of NGF-differentiated PC 12 cells.

Tetanus toxin-sensitive VAMP-related proteins are present in murine macrophages.

The N-terminal half of the receptor domain of botulinum neurotoxin A binds to microdomains of the plasma membrane

The metallo-proteinase activity of tetanus and botulism neurotoxins ⬇️

The thioredoxin reductase-thioredoxin system is involved in the entry of tetanus and botulinum neurotoxins in the cytosol of nerve terminals.

Thioredoxin and its reductase are present on synaptic vesicles, and their inhibition prevents the paralysis induced by botulinum neurotoxins.

Time course and temperature dependence of the membrane translocation of tetanus and botulinum neurotoxins C and D in neurons ⬇️

Toxicity of botulinum neurotoxins in central nervous system of mice

Traffic of botulinum toxins A and E in excitatory and inhibitory neurons.

Transient synaptic silencing of developing striate cortex has persistent effects on visual function and plasticity

VAMP/synaptobrevin cleavage by tetanus and botulinum neurotoxins is strongly enhanced by acidic liposomes

Vesicle-associated membrane protein (VAMP)/synaptobrevin-2 is associated with dense core secretory granules in PC12 neuroendocrine cells.