Lista de obras - Sergio Fucile - Dominio Público Uruguay

About a new method to measure fractional Ca2+ currents through ligand-gated ion channels

artículo científico publicado en 2009

Activation of the nicotinic acetylcholine receptor mobilizes calcium from caffeine-insensitive stores in C2C12 mouse myotubes.

artículo científico publicado en 1993

Acute and chronic effects of hypercalcaemia on cortical excitability as studied by 5 Hz repetitive transcranial magnetic stimulation

Adenosine receptor antagonists alter the stability of human epileptic GABAA receptors.

artículo científico publicado en 2008

Bifunctional compounds targeting both D2 and non-α7 nACh receptors: design, synthesis and pharmacological characterization.

artículo científico publicado en 2015

CC4, a dimer of cytisine, is a selective partial agonist at α4β2/α6β2 nAChR with improved selectivity for tobacco smoking cessation.

artículo científico publicado en 2013

Ca2+ permeability of nicotinic acetylcholine receptors from rat dorsal root ganglion neurones

scientific journal article

Chemistry and Pharmacology of a Series of Unichiral Analogues of 2-(2-Pyrrolidinyl)-1,4-benzodioxane, Prolinol Phenyl Ether, and Prolinol 3-Pyridyl Ether Designed as α4β2-Nicotinic Acetylcholine Receptor Agonists

artículo científico publicado en 2015

Chemokine receptor CXCR2 regulates the functional properties of AMPA-type glutamate receptor GluR1 in HEK cells.

artículo científico publicado en 2002

Cholinergic stimulation of human microcytoma cell line H69.

artículo científico publicado en 1997

Comparison of glycine and GABA actions on the zebrafish homomeric glycine receptor.

artículo científico publicado en 1999

Crucial role of nicotinic α5 subunit variants for Ca2+ fluxes in ventral midbrain neurons

artículo científico publicado en 2015

Cyclin D1 degradation enhances endothelial cell survival upon oxidative stress

artículo científico publicado en 2006

Cysteine residues are critical for chemokine receptor CXCR2 functional properties

artículo científico publicado en 2005

Design, synthesis, and pharmacological characterization of novel spirocyclic quinuclidinyl-Δ2-isoxazoline derivatives as potent and selective agonists of α7 nicotinic acetylcholine receptors

artículo científico publicado en 2011

Electrophysiological properties of mouse bone marrow c-kit+ cells co-cultured onto neonatal cardiac myocytes.

artículo científico publicado en 2005

Enhancement of GABA(A)-current run-down in the hippocampus occurs at the first spontaneous seizure in a model of temporal lobe epilepsy.

artículo científico publicado en 2010

Expression of the K+/Cl- cotransporter, KCC2, in cerebellar Purkinje cells is regulated by group-I metabotropic glutamate receptors.

artículo científico publicado en 2016

Extracellular mild acidosis decreases the Ca2+ permeability of the human NMDA receptors

scientific article published on 04 April 2019

FTY720 (fingolimod) is a neuroprotective and disease-modifying agent in cellular and mouse models of Huntington disease.

artículo científico publicado en 2013

Fast potentiation of glycine receptor channels of intracellular calcium in neurons and transfected cells

artículo científico publicado en 2000

Fluoxetine prevents acetylcholine-induced excitotoxicity blocking human endplate acetylcholine receptor

artículo científico publicado en 2013

Fractalkine/CX3CL1 modulates GABAA currents in human temporal lobe epilepsy

artículo científico publicado en 2013

From pyrrolidinyl-benzodioxane to pyrrolidinyl-pyridodioxanes, or from unselective antagonism to selective partial agonism at α4β2 nicotinic acetylcholine receptor.

artículo científico publicado en 2016

Functional properties of cells obtained from human cord blood CD34+ stem cells and mouse cardiac myocytes in coculture.

artículo científico publicado en 2008

Functional properties of neuronal nicotinic acetylcholine receptor channels expressed in transfected human cells.

artículo científico publicado en 1997

Functional properties of neurons derived from fetal mouse neurospheres are compatible with those of neuronal precursors in vivo

artículo científico publicado en 2006

Genetic Analysis Reveals a Longevity-Associated Protein Modulating Endothelial Function and Angiogenesis

artículo científico publicado en 2015

Homeostatic control of synaptic activity by endogenous adenosine is mediated by adenosine kinase.

artículo científico publicado en 2012

Human iPSC Modeling of Genetic Febrile Seizure Reveals Aberrant Molecular and Physiological Features Underlying an Impaired Neuronal Activity

artículo científico publicado en 2022

Identification of a determinant of acetylcholine receptor gating kinetics in the extracellular portion of the gamma subunit.

artículo científico publicado en 1996

Investigating the hydrogen-bond acceptor site of the nicotinic pharmacophore model: a computational and experimental study using epibatidine-related molecular probes

artículo científico publicado en 2013

LAV-BPIFB4 isoform modulates eNOS signalling through Ca2+/PKC-alpha-dependent mechanism

artículo científico publicado en 2017

Loss of constitutive functional γ-aminobutyric acid type A-B receptor crosstalk in layer 5 pyramidal neurons of human epileptic temporal cortex

artículo científico publicado en 2017

Mechanism of verapamil action on wild-type and slow-channel mutant human muscle acetylcholine receptor.

artículo científico publicado en 2010

Modification of the anabaseine pyridine nucleus allows achieving binding and functional selectivity for the α3β4 nicotinic acetylcholine receptor subtype

artículo científico publicado en 2015

Modulation of the Ca(2+) permeability of human endplate acetylcholine receptor-channel.

artículo científico publicado en 2011

New spirocyclic Δ²-isoxazoline derivatives related to selective agonists of α7 neuronal nicotinic acetylcholine receptors

artículo científico publicado en 2011

Nicotinic cholinergic stimulation promotes survival and reduces motility of cultured rat cerebellar granule cells.

artículo científico publicado en 2004

PI3Kγ inhibition reduces blood pressure by a vasorelaxant Akt/L-type calcium channel mechanism

artículo científico publicado en 2011

Rare missense variants of neuronal nicotinic acetylcholine receptor altering receptor function are associated with sporadic amyotrophic lateral sclerosis

artículo científico publicado en 2009

Serotonin antagonizes the human neuronal alpha7 nicotinic acetylcholine receptor and becomes an agonist after L248T alpha7 mutation.

artículo científico publicado en 2002

Spontaneous and evoked oscillations of cytosolic calcium in the freshly prepared ciliary epithelial bilayer of the rabbit eye

scientific article published on 01 March 1996

The Distribution of Charged Amino Acid Residues and the Ca2+ Permeability of Nicotinic Acetylcholine Receptors: A Predictive Model.

artículo científico publicado en 2017

Lista de obras de Sergio Fucile

About a new method to measure fractional Ca2+ currents through ligand-gated ion channels

Activation of the nicotinic acetylcholine receptor mobilizes calcium from caffeine-insensitive stores in C2C12 mouse myotubes.

Acute and chronic effects of hypercalcaemia on cortical excitability as studied by 5 Hz repetitive transcranial magnetic stimulation

Adenosine receptor antagonists alter the stability of human epileptic GABAA receptors.

Bifunctional compounds targeting both D2 and non-α7 nACh receptors: design, synthesis and pharmacological characterization.

CC4, a dimer of cytisine, is a selective partial agonist at α4β2/α6β2 nAChR with improved selectivity for tobacco smoking cessation.

Ca2+ permeability of nicotinic acetylcholine receptors from rat dorsal root ganglion neurones

Chemistry and Pharmacology of a Series of Unichiral Analogues of 2-(2-Pyrrolidinyl)-1,4-benzodioxane, Prolinol Phenyl Ether, and Prolinol 3-Pyridyl Ether Designed as α4β2-Nicotinic Acetylcholine Receptor Agonists

Chemokine receptor CXCR2 regulates the functional properties of AMPA-type glutamate receptor GluR1 in HEK cells.

Cholinergic stimulation of human microcytoma cell line H69.

Comparison of glycine and GABA actions on the zebrafish homomeric glycine receptor.

Crucial role of nicotinic α5 subunit variants for Ca2+ fluxes in ventral midbrain neurons

Cyclin D1 degradation enhances endothelial cell survival upon oxidative stress

Cysteine residues are critical for chemokine receptor CXCR2 functional properties

Design, synthesis, and pharmacological characterization of novel spirocyclic quinuclidinyl-Δ2-isoxazoline derivatives as potent and selective agonists of α7 nicotinic acetylcholine receptors

Electrophysiological properties of mouse bone marrow c-kit+ cells co-cultured onto neonatal cardiac myocytes.

Enhancement of GABA(A)-current run-down in the hippocampus occurs at the first spontaneous seizure in a model of temporal lobe epilepsy.

Expression of the K+/Cl- cotransporter, KCC2, in cerebellar Purkinje cells is regulated by group-I metabotropic glutamate receptors.

Extracellular mild acidosis decreases the Ca2+ permeability of the human NMDA receptors

FTY720 (fingolimod) is a neuroprotective and disease-modifying agent in cellular and mouse models of Huntington disease.

Fast potentiation of glycine receptor channels of intracellular calcium in neurons and transfected cells

Fluoxetine prevents acetylcholine-induced excitotoxicity blocking human endplate acetylcholine receptor

Fractalkine/CX3CL1 modulates GABAA currents in human temporal lobe epilepsy

From pyrrolidinyl-benzodioxane to pyrrolidinyl-pyridodioxanes, or from unselective antagonism to selective partial agonism at α4β2 nicotinic acetylcholine receptor.

Functional properties of cells obtained from human cord blood CD34+ stem cells and mouse cardiac myocytes in coculture.

Functional properties of neuronal nicotinic acetylcholine receptor channels expressed in transfected human cells.

Functional properties of neurons derived from fetal mouse neurospheres are compatible with those of neuronal precursors in vivo

Genetic Analysis Reveals a Longevity-Associated Protein Modulating Endothelial Function and Angiogenesis

Homeostatic control of synaptic activity by endogenous adenosine is mediated by adenosine kinase.

Human iPSC Modeling of Genetic Febrile Seizure Reveals Aberrant Molecular and Physiological Features Underlying an Impaired Neuronal Activity

Identification of a determinant of acetylcholine receptor gating kinetics in the extracellular portion of the gamma subunit.

Investigating the hydrogen-bond acceptor site of the nicotinic pharmacophore model: a computational and experimental study using epibatidine-related molecular probes

LAV-BPIFB4 isoform modulates eNOS signalling through Ca2+/PKC-alpha-dependent mechanism

Loss of constitutive functional γ-aminobutyric acid type A-B receptor crosstalk in layer 5 pyramidal neurons of human epileptic temporal cortex

Mechanism of verapamil action on wild-type and slow-channel mutant human muscle acetylcholine receptor.

Modification of the anabaseine pyridine nucleus allows achieving binding and functional selectivity for the α3β4 nicotinic acetylcholine receptor subtype

Modulation of the Ca(2+) permeability of human endplate acetylcholine receptor-channel.

New spirocyclic Δ²-isoxazoline derivatives related to selective agonists of α7 neuronal nicotinic acetylcholine receptors

Nicotinic cholinergic stimulation promotes survival and reduces motility of cultured rat cerebellar granule cells.

PI3Kγ inhibition reduces blood pressure by a vasorelaxant Akt/L-type calcium channel mechanism

Rare missense variants of neuronal nicotinic acetylcholine receptor altering receptor function are associated with sporadic amyotrophic lateral sclerosis

Serotonin antagonizes the human neuronal alpha7 nicotinic acetylcholine receptor and becomes an agonist after L248T alpha7 mutation.

Spontaneous and evoked oscillations of cytosolic calcium in the freshly prepared ciliary epithelial bilayer of the rabbit eye

The Distribution of Charged Amino Acid Residues and the Ca2+ Permeability of Nicotinic Acetylcholine Receptors: A Predictive Model.