Lista de obras - Petri Kursula - Dominio Público Uruguay

A Quasielastic Neutron Scattering Investigation on the Molecular Self-Dynamics of Human Myelin Protein P2

artículo científico publicado en 2019

A previously unobserved conformation for the human Pex5p receptor suggests roles for intrinsic flexibility and rigid domain motions in ligand binding

artículo científico publicado en 2007

A structural insight into lead neurotoxicity and calmodulin activation by heavy metals

artículo científico publicado en 2007

Accurate solution structures of proteins from X-ray data and a minimal set of NMR data: calmodulin-peptide complexes as examples

artículo científico publicado en 2009

Antagonistic Functions of MBP and CNP Establish Cytosolic Channels in CNS Myelin

artículo científico publicado en 2017

Assembly of the elongated collagen prolyl 4-hydroxylase α2β2 heterotetramer around a central α2 dimer.

artículo científico publicado en 2017

Atomic resolution view into the structure–function relationships of the human myelin peripheral membrane protein P2

artículo científico publicado en 2014

CHCHD10 mutations p.R15L and p.G66V cause motoneuron disease by haploinsufficiency

artículo científico publicado en 2018

Calcium modulates calmodulin/α-actinin 1 interaction with and agonist-dependent internalization of the adenosine A2A receptor.

artículo científico publicado en 2017

Charge isomers of myelin basic protein: structure and interactions with membranes, nucleotide analogues, and calmodulin

artículo científico publicado en 2011

Cofactor mobility determines reaction outcome in the IMPDH and GMPR (β-α)8 barrel enzymes

artículo científico publicado en 2011

Collapsin Response Mediator Protein-2 (CRMP2) is a Plausible Etiological Factor and Potential Therapeutic Target in Alzheimer's Disease: Comparison and Contrast with Microtubule-Associated Protein Tau

artículo científico publicado en 2016

Collapsin response mediator protein 2: high-resolution crystal structure sheds light on small-molecule binding, post-translational modifications, and conformational flexibility

artículo científico publicado en 2017

Conformations of peptides derived from myelin-specific proteins in membrane-mimetic conditions probed by synchrotron radiation CD spectroscopy

artículo científico publicado en 2011

Cryo-EM, X-ray diffraction, and atomistic simulations reveal determinants for the formation of a supramolecular myelin-like proteolipid lattice

scientific article published on 07 April 2020

Crystal and solution structure of NDRG1, a membrane-binding protein linked to myelination and tumour suppression

scientific article published on 10 December 2020

Crystal and solution structure, stability and post-translational modifications of collapsin response mediator protein 2

artículo científico publicado en 2008

Crystal and solution structures reveal oligomerization of individual capsid homology domains of Drosophila Arc

artículo científico publicado en 2021

Crystal structure of human inosine triphosphatase. Substrate binding and implication of the inosine triphosphatase deficiency mutation P32T.

artículo científico publicado en 2006

Crystallographic analysis of the reaction cycle of 2',3'-cyclic nucleotide 3'-phosphodiesterase, a unique member of the 2H phosphoesterase family

artículo científico publicado en 2013

Crystallographic anomalous diffraction data for the experimental phasing of two myelin proteins, gliomedin and periaxin.

artículo científico

Crystallographic home-source X-ray data for the atomic-resolution experimental phasing of the Shank3 SH3 domain structure from pseudomerohedrally twinned crystals

artículo científico publicado en 2018

Crystallographic snapshots of initial steps in the collapse of the calmodulin central helix

artículo científico publicado en 2014

Death-Associated Protein Kinase Activity Is Regulated by Coupled Calcium/Calmodulin Binding to Two Distinct Sites

artículo científico publicado en 2016

Determinants of ligand binding and catalytic activity in the myelin enzyme 2',3'-cyclic nucleotide 3'-phosphodiesterase

artículo científico publicado en 2015

Domain Swapping and Different Oligomeric States for the Complex Between Calmodulin and the Calmodulin-Binding Domain of Calcineurin A

artículo científico publicado en 2009

Dynamics of the Peripheral Membrane Protein P2 from Human Myelin Measured by Neutron Scattering--A Comparison between Wild-Type Protein and a Hinge Mutant

artículo científico publicado en 2015

Effects of gigapascal level pressure on protein structure and function.

artículo científico publicado en 2012

Expression, purification, and initial characterization of different domains of recombinant mouse 2',3'-cyclic nucleotide 3'-phosphodiesterase, an enigmatic enzyme from the myelin sheath.

artículo científico publicado en 2010

Flexible Players within the Sheaths: The Intrinsically Disordered Proteins of Myelin in Health and Disease

artículo científico publicado en 2020

Functional homo- and heterodimeric actin capping proteins from the malaria parasite

scientific article published on 02 March 2020

GADL1 is a multifunctional decarboxylase with tissue-specific roles in β-alanine and carnosine production

artículo científico publicado en 2020

Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia

artículo científico publicado en 2015

High resolution crystal structures of human cytosolic thiolase (CT): a comparison of the active sites of human CT, bacterial thiolase, and bacterial KAS I.

artículo científico publicado en 2005

High-affinity anti-Arc nanobodies provide tools for structural and functional studies

artículo científico publicado en 2022

High-affinity heterotetramer formation between the large myelin-associated glycoprotein and the dynein light chain DYNLL1

scientific article published on 26 November 2018

High-resolution structural analysis of mammalian profilin 2a complex formation with two physiological ligands: the formin homology 1 domain of mDia1 and the proline-rich domain of VASP

artículo científico publicado en 2008

How Does Protein Zero Assemble Compact Myelin?

scientific article published on 04 August 2020

Human Δ³,Δ²-enoyl-CoA isomerase, type 2: a structural enzymology study on the catalytic role of its ACBP domain and helix-10

artículo científico publicado en 2015

Interaction between the C-terminal region of human myelin basic protein and calmodulin: analysis of complex formation and solution structure

artículo científico publicado en 2008

Ionic strength and calcium regulate membrane interactions of myelin basic protein and the cytoplasmic domain of myelin protein zero

scientific article published on 10 February 2019

Juxtanodin is an intrinsically disordered F-actin-binding protein

artículo científico publicado en 2012

Lipid membrane association of myelin proteins and peptide segments studied by oriented and synchrotron radiation circular dichroism spectroscopy.

artículo científico publicado en 2013

Membrane Association Landscape of Myelin Basic Protein Portrays Formation of the Myelin Major Dense Line

artículo científico publicado en 2017

Molecular basis of the death-associated protein kinase-calcium/calmodulin regulator complex

artículo científico publicado en 2010

Molecular mechanisms of Charcot-Marie-Tooth neuropathy linked to mutations in human myelin protein P2.

artículo científico publicado en 2017

Molecular structure and function of myelin protein P0 in membrane stacking

artículo científico publicado en 2019

Myelin 2′,3′-Cyclic Nucleotide 3′-Phosphodiesterase: Active-Site Ligand Binding and Molecular Conformation ⬇️

artículo científico publicado el 29 de febrero de 2012

Myelin basic protein and myelin protein 2 act synergistically to cause stacking of lipid bilayers

scientific journal article

Myelin-specific proteins: a structurally diverse group of membrane-interacting molecules

artículo científico publicado en 2013

Neuropathy-related mutations alter the membrane binding properties of the human myelin protein P0 cytoplasmic tail

scientific article published on 07 June 2019

Periaxin and AHNAK Nucleoprotein 2 Form Intertwined Homodimers through Domain Swapping

artículo científico publicado en 2014

Phosphatidylserine receptors enhance SARS-CoV-2 infection

artículo científico publicado en 2021

Publisher Correction: Molecular mechanisms of Charcot-Marie-Tooth neuropathy linked to mutations in human myelin protein P2.

artículo científico publicado en 2018

Purification of recombinant growth hormone by clear native gels for conformational analyses: preservation of conformation and receptor binding

artículo científico publicado en 2010

Purification, crystallization and preliminary X-ray crystallographic analysis of MIL, a glycosylated jacalin-related lectin from mulberry (Morus indica) latex.

artículo científico publicado en 2011

Recognition of a Functional Peroxisome Type 1 Target by the Dynamic Import Receptor Pex5p

artículo científico publicado en 2006

Recognition of mono-ADP-ribosylated ARTD10 substrates by ARTD8 macrodomains

artículo científico publicado en 2013

Recombinant production, crystallization and preliminary structural characterization of Schistosoma japonicum profilin

artículo científico publicado en 2013

SUMO on CRMPs - wrestling for pain?

artículo científico publicado en 2017

Shanks - multidomain molecular scaffolds of the postsynaptic density

artículo científico publicado en 2019

Sister Chromatid Cohesion Establishment Factor ESCO1 Operates by Substrate-Assisted Catalysis

artículo científico publicado en 2016

Stability and flexibility of full-length human oligodendrocytic QKI6

scientific article published on 23 September 2019

Structural Characterization of Functionally Important Chloride Binding Sites in the Marine <i>Vibrio</i> Alkaline Phosphatase

artículo científico publicado en 2022

Structural analysis of the complex between calmodulin and full-length myelin basic protein, an intrinsically disordered molecule

scientific journal article

Structural and biophysical characterization of transcription factor HNF-1A as a tool to study MODY3 diabetes variants

artículo científico publicado en 2022

Structural and functional characterization of human peripheral nervous system myelin protein P2

artículo científico publicado en 2010

Structural and functional evolution of 2',3'-cyclic nucleotide 3'-phosphodiesterase.

artículo científico publicado en 2015

Structural aspects of nucleotide ligand binding by a bacterial 2H phosphoesterase

artículo científico publicado en 2017

Structural basis for PDZ domain interactions in the post-synaptic density scaffolding protein Shank3.

artículo científico publicado en 2018

Structural basis for parasite-specific functions of the divergent profilin of Plasmodium falciparum

artículo científico publicado en 2008

Structural properties and role of the endocannabinoid lipases ABHD6 and ABHD12 in lipid signalling and disease

scientific article published on 18 December 2018

Structural similarities and functional differences clarify evolutionary relationships between tRNA healing enzymes and the myelin enzyme CNPase

artículo científico publicado en 2017

Structure and dynamics of a human myelin protein P2 portal region mutant indicate opening of the β barrel in fatty acid binding proteins.

artículo científico publicado en 2018

Structure of an unconventional SH3 domain from the postsynaptic density protein Shank3 at ultrahigh resolution.

artículo científico publicado en 2017

Structure of monomeric full-length ARC sheds light on molecular flexibility, protein interactions, and functional modalities

artículo científico publicado en 2018

Structure of the ALS Mutation Target Annexin A11 Reveals a Stabilising N-Terminal Segment

scientific article published on 24 April 2020

Structure of the dimeric autoinhibited conformation of DAPK2, a pro-apoptotic protein kinase

artículo científico publicado en 2011

Structure, modifications and ligand-binding properties of rat profilin 2a

artículo científico publicado en 2009

Sub-Atomic Resolution Crystal Structures Reveal Conserved Geometric Outliers at Functional Sites

scientific article published on 22 August 2019

Testis-expressed profilins 3 and 4 show distinct functional characteristics and localize in the acroplaxome-manchette complex in spermatids

artículo científico publicado en 2009

The N-terminal Domain of Unknown Function (DUF959) in Collagen XVIII is Intrinsically Disordered and Highly O-glycosylated

artículo científico publicado en 2018

The N-terminal domain of the myelin enzyme 2',3'-cyclic nucleotide 3'-phosphodiesterase: direct molecular interaction with the calcium sensor calmodulin

artículo científico publicado en 2012

The catalytic cycle of biosynthetic thiolase: a conformational journey of an acetyl group through four binding modes and two oxyanion holes

artículo científico publicado en 2002

The lasso segment is required for functional dimerization of the Plasmodium formin 1 FH2 domain

artículo científico publicado en 2012

The olfactomedin domain from gliomedin is a β-propeller with unique structural properties.

artículo científico publicado en 2014

The quaternary structure of human tyrosine hydroxylase: effects of dystonia-associated missense variants on oligomeric state and enzyme activity

artículo científico publicado en 2018

The structural motifs for substrate binding and dimerization of the α subunit of collagen prolyl 4-hydroxylase

artículo científico publicado en 2013

The structure of human collapsin response mediator protein 2, a regulator of axonal growth

artículo científico publicado en 2007

The sulfur atoms of the substrate CoA and the catalytic cysteine are required for a productive mode of substrate binding in bacterial biosynthetic thiolase, a thioester-dependent enzyme

artículo científico publicado en 2008

The thiolase reaction mechanism: the importance of Asn316 and His348 for stabilizing the enolate intermediate of the Claisen condensation

artículo científico publicado en 2009

Two independently folding units of Plasmodium profilin suggest evolution via gene fusion

artículo científico publicado en 2015

Lista de obras de Petri Kursula

A Quasielastic Neutron Scattering Investigation on the Molecular Self-Dynamics of Human Myelin Protein P2

A previously unobserved conformation for the human Pex5p receptor suggests roles for intrinsic flexibility and rigid domain motions in ligand binding

A structural insight into lead neurotoxicity and calmodulin activation by heavy metals

Accurate solution structures of proteins from X-ray data and a minimal set of NMR data: calmodulin-peptide complexes as examples

Antagonistic Functions of MBP and CNP Establish Cytosolic Channels in CNS Myelin

Assembly of the elongated collagen prolyl 4-hydroxylase α2β2 heterotetramer around a central α2 dimer.

Atomic resolution view into the structure–function relationships of the human myelin peripheral membrane protein P2

CHCHD10 mutations p.R15L and p.G66V cause motoneuron disease by haploinsufficiency

Calcium modulates calmodulin/α-actinin 1 interaction with and agonist-dependent internalization of the adenosine A2A receptor.

Charge isomers of myelin basic protein: structure and interactions with membranes, nucleotide analogues, and calmodulin

Cofactor mobility determines reaction outcome in the IMPDH and GMPR (β-α)8 barrel enzymes

Collapsin Response Mediator Protein-2 (CRMP2) is a Plausible Etiological Factor and Potential Therapeutic Target in Alzheimer's Disease: Comparison and Contrast with Microtubule-Associated Protein Tau

Collapsin response mediator protein 2: high-resolution crystal structure sheds light on small-molecule binding, post-translational modifications, and conformational flexibility

Conformations of peptides derived from myelin-specific proteins in membrane-mimetic conditions probed by synchrotron radiation CD spectroscopy

Cryo-EM, X-ray diffraction, and atomistic simulations reveal determinants for the formation of a supramolecular myelin-like proteolipid lattice

Crystal and solution structure of NDRG1, a membrane-binding protein linked to myelination and tumour suppression

Crystal and solution structure, stability and post-translational modifications of collapsin response mediator protein 2

Crystal and solution structures reveal oligomerization of individual capsid homology domains of Drosophila Arc

Crystal structure of human inosine triphosphatase. Substrate binding and implication of the inosine triphosphatase deficiency mutation P32T.

Crystallographic analysis of the reaction cycle of 2',3'-cyclic nucleotide 3'-phosphodiesterase, a unique member of the 2H phosphoesterase family

Crystallographic anomalous diffraction data for the experimental phasing of two myelin proteins, gliomedin and periaxin.

Crystallographic home-source X-ray data for the atomic-resolution experimental phasing of the Shank3 SH3 domain structure from pseudomerohedrally twinned crystals

Crystallographic snapshots of initial steps in the collapse of the calmodulin central helix

Death-Associated Protein Kinase Activity Is Regulated by Coupled Calcium/Calmodulin Binding to Two Distinct Sites

Determinants of ligand binding and catalytic activity in the myelin enzyme 2',3'-cyclic nucleotide 3'-phosphodiesterase

Domain Swapping and Different Oligomeric States for the Complex Between Calmodulin and the Calmodulin-Binding Domain of Calcineurin A

Dynamics of the Peripheral Membrane Protein P2 from Human Myelin Measured by Neutron Scattering--A Comparison between Wild-Type Protein and a Hinge Mutant

Effects of gigapascal level pressure on protein structure and function.

Expression, purification, and initial characterization of different domains of recombinant mouse 2',3'-cyclic nucleotide 3'-phosphodiesterase, an enigmatic enzyme from the myelin sheath.

Flexible Players within the Sheaths: The Intrinsically Disordered Proteins of Myelin in Health and Disease

Functional homo- and heterodimeric actin capping proteins from the malaria parasite

GADL1 is a multifunctional decarboxylase with tissue-specific roles in β-alanine and carnosine production

Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia

High resolution crystal structures of human cytosolic thiolase (CT): a comparison of the active sites of human CT, bacterial thiolase, and bacterial KAS I.

High-affinity anti-Arc nanobodies provide tools for structural and functional studies

High-affinity heterotetramer formation between the large myelin-associated glycoprotein and the dynein light chain DYNLL1

High-resolution structural analysis of mammalian profilin 2a complex formation with two physiological ligands: the formin homology 1 domain of mDia1 and the proline-rich domain of VASP

How Does Protein Zero Assemble Compact Myelin?

Human Δ³,Δ²-enoyl-CoA isomerase, type 2: a structural enzymology study on the catalytic role of its ACBP domain and helix-10

Interaction between the C-terminal region of human myelin basic protein and calmodulin: analysis of complex formation and solution structure

Ionic strength and calcium regulate membrane interactions of myelin basic protein and the cytoplasmic domain of myelin protein zero

Juxtanodin is an intrinsically disordered F-actin-binding protein

Lipid membrane association of myelin proteins and peptide segments studied by oriented and synchrotron radiation circular dichroism spectroscopy.

Membrane Association Landscape of Myelin Basic Protein Portrays Formation of the Myelin Major Dense Line

Molecular basis of the death-associated protein kinase-calcium/calmodulin regulator complex

Molecular mechanisms of Charcot-Marie-Tooth neuropathy linked to mutations in human myelin protein P2.

Molecular structure and function of myelin protein P0 in membrane stacking

Myelin 2′,3′-Cyclic Nucleotide 3′-Phosphodiesterase: Active-Site Ligand Binding and Molecular Conformation ⬇️

Myelin basic protein and myelin protein 2 act synergistically to cause stacking of lipid bilayers

Myelin-specific proteins: a structurally diverse group of membrane-interacting molecules

Neuropathy-related mutations alter the membrane binding properties of the human myelin protein P0 cytoplasmic tail

Periaxin and AHNAK Nucleoprotein 2 Form Intertwined Homodimers through Domain Swapping

Phosphatidylserine receptors enhance SARS-CoV-2 infection

Publisher Correction: Molecular mechanisms of Charcot-Marie-Tooth neuropathy linked to mutations in human myelin protein P2.

Purification of recombinant growth hormone by clear native gels for conformational analyses: preservation of conformation and receptor binding

Purification, crystallization and preliminary X-ray crystallographic analysis of MIL, a glycosylated jacalin-related lectin from mulberry (Morus indica) latex.

Recognition of a Functional Peroxisome Type 1 Target by the Dynamic Import Receptor Pex5p

Recognition of mono-ADP-ribosylated ARTD10 substrates by ARTD8 macrodomains

Recombinant production, crystallization and preliminary structural characterization of Schistosoma japonicum profilin

SUMO on CRMPs - wrestling for pain?

Shanks - multidomain molecular scaffolds of the postsynaptic density

Sister Chromatid Cohesion Establishment Factor ESCO1 Operates by Substrate-Assisted Catalysis

Stability and flexibility of full-length human oligodendrocytic QKI6

Structural Characterization of Functionally Important Chloride Binding Sites in the Marine <i>Vibrio</i> Alkaline Phosphatase

Structural analysis of the complex between calmodulin and full-length myelin basic protein, an intrinsically disordered molecule

Structural and biophysical characterization of transcription factor HNF-1A as a tool to study MODY3 diabetes variants

Structural and functional characterization of human peripheral nervous system myelin protein P2

Structural and functional evolution of 2',3'-cyclic nucleotide 3'-phosphodiesterase.

Structural aspects of nucleotide ligand binding by a bacterial 2H phosphoesterase

Structural basis for PDZ domain interactions in the post-synaptic density scaffolding protein Shank3.

Structural basis for parasite-specific functions of the divergent profilin of Plasmodium falciparum

Structural properties and role of the endocannabinoid lipases ABHD6 and ABHD12 in lipid signalling and disease

Structural similarities and functional differences clarify evolutionary relationships between tRNA healing enzymes and the myelin enzyme CNPase

Structure and dynamics of a human myelin protein P2 portal region mutant indicate opening of the β barrel in fatty acid binding proteins.

Structure of an unconventional SH3 domain from the postsynaptic density protein Shank3 at ultrahigh resolution.

Structure of monomeric full-length ARC sheds light on molecular flexibility, protein interactions, and functional modalities

Structure of the ALS Mutation Target Annexin A11 Reveals a Stabilising N-Terminal Segment

Structure of the dimeric autoinhibited conformation of DAPK2, a pro-apoptotic protein kinase

Structure, modifications and ligand-binding properties of rat profilin 2a