Lista de obras - Matthias Brock - Dominio Público Uruguay

A Non-canonical Melanin Biosynthesis Pathway Protects Aspergillus terreus Conidia from Environmental Stress ⬇️

artículo científico publicado en 2016

A highly conserved basidiomycete peptide synthetase produces a trimeric hydroxamate siderophore ⬇️

artículo científico publicado en 2017

A multimodal imaging approach enables in vivo assessment of antifungal treatment in a mouse model of invasive pulmonary aspergillosis.

artículo científico publicado en 2018

A new high-performance heterologous fungal expression system based on regulatory elements from the Aspergillus terreus terrein gene cluster.

artículo científico publicado en 2015

ATNT: an enhanced system for expression of polycistronic secondary metabolite gene clusters in Aspergillus niger

artículo científico publicado en 2017

Acryloyl-CoA reductase from Clostridium propionicum. An enzyme complex of propionyl-CoA dehydrogenase and electron-transferring flavoprotein.

artículo científico publicado en 2003

Analysis of the regulation, expression, and localisation of the isocitrate lyase from Aspergillus fumigatus, a potential target for antifungal drug development.

artículo científico publicado en 2006

Application of bioluminescence imaging for in vivo monitoring of fungal infections.

artículo científico publicado en 2011

Aspergillus nidulans DigA, a potential homolog of Saccharomyces cerevisiae Pep3 (Vps18), is required for nuclear migration, mitochondrial morphology and polarized growth.

artículo científico publicado en 2001

Aspergillus terreus Species Complex

scientific article published in 2021

Assessment of efficacy of antifungals against Aspergillus fumigatus: value of real-time bioluminescence imaging.

artículo científico publicado en 2013

Back to the roots.

artículo científico publicado en 2009

Bioluminescent Aspergillus fumigatus, a new tool for drug efficiency testing and in vivo monitoring of invasive aspergillosis ⬇️

artículo científico publicado en 2008

Bringing light into the dark site of infection

scientific article published on 28 May 2015

Candida albicans Hap43 Domains Are Required under Iron Starvation but Not Excess.

artículo científico publicado en 2017

Candida albicans scavenges host zinc via Pra1 during endothelial invasion ⬇️

artículo científico publicado en 2012

Candida albicans utilizes a modified β-oxidation pathway for the degradation of toxic propionyl-CoA.

artículo científico publicado en 2014

Candida glabrata tryptophan-based pigment production via the Ehrlich pathway

artículo científico publicado en 2010

Characterisation of the laccase-encoding gene abr2 of the dihydroxynaphthalene-like melanin gene cluster of Aspergillus fumigatus

artículo científico publicado en 2006

Characterization of an acyl-CoA: carboxylate CoA-transferase from Aspergillus nidulans involved in propionyl-CoA detoxification.

artículo científico publicado en 2008

Connection of propionyl-CoA metabolism to polyketide biosynthesis in Aspergillus nidulans.

artículo científico publicado en 2004

Crystal Structure of 2-Methylisocitrate Lyase (PrpB) from Escherichia coli and Modelling of its Ligand Bound Active Centre ⬇️

artículo científico publicado el 2 de mayo de 2003

DIGE enables the detection of a putative serum biomarker of fungal origin in a mouse model of invasive aspergillosis

artículo científico publicado en 2012

Duality of liver and kidney lesions after systemic infection of immunosuppressed and immunocompetent mice with Aspergillus fumigatus.

artículo científico publicado en 2012

Dynamic Immune Cell Recruitment After Murine Pulmonary Aspergillus fumigatus Infection under Different Immunosuppressive Regimens

artículo científico publicado en 2016

Embryonated eggs as an alternative infection model to investigate Aspergillus fumigatus virulence

artículo científico publicado en 2010

Encapsulation of Antifungals in Micelles Protects Candida albicans during Gall-Bladder Infection.

artículo científico publicado en 2017

Environmental dimensionality controls the interaction of phagocytes with the pathogenic fungi Aspergillus fumigatus and Candida albicans

artículo científico publicado en 2007

Evaluation of lysine biosynthesis as an antifungal drug target: biochemical characterization of Aspergillus fumigatus homocitrate synthase and virulence studies

artículo científico publicado en 2010

Exploring metabolic pathways in genome-scale networks via generating flux modes

artículo científico publicado en 2010

Fungal metabolism in host niches.

artículo científico publicado en 2009

Gene acquisition, duplication and metabolic specification: the evolution of fungal methylisocitrate lyases

artículo científico publicado en 2011

Generation and phenotypic characterization of Aspergillus nidulans methylisocitrate lyase deletion mutants: methylisocitrate inhibits growth and conidiation.

artículo científico publicado en 2005

Hybrid in silico/in vitro target fishing to assign function to “orphan” compounds of food origin – The case of the fungal metabolite atromentin

artículo científico publicado en 2018

Illuminating fungal infections with bioluminescence.

artículo científico publicado en 2014

In vivo bioluminescence imaging and histopathopathologic analysis reveal distinct roles for resident and recruited immune effector cells in defense against invasive aspergillosis

artículo científico publicado en 2010

In vivo imaging of disseminated murine Candida albicans infection reveals unexpected host sites of fungal persistence during antifungal therapy

artículo científico publicado en 2014

Infection-Mediated Priming of Phagocytes Protects against Lethal Secondary Aspergillus fumigatus Challenge

artículo científico publicado en 2016

Lipid components of bile increase the protective effect of conjugated bile salts against antifungal drugs.

artículo científico publicado en 2017

Longitudinal multimodal imaging-compatible mouse model of triazole-sensitive and -resistant invasive pulmonary aspergillosis

scientific article published in 2022

Lysine biosynthesis in microbes: relevance as drug target and prospects for β-lactam antibiotics production.

artículo científico

Methylcitrate cycle activation during adaptation of Fusarium solani and Fusarium verticillioides to propionyl-CoA-generating carbon sources.

artículo científico publicado en 2009

Methylcitrate synthase from Aspergillus fumigatus is essential for manifestation of invasive aspergillosis.

artículo científico publicado en 2008

Methylcitrate synthase from Aspergillus fumigatus. Propionyl-CoA affects polyketide synthesis, growth and morphology of conidia.

artículo científico publicado en 2005

Molecular epidemiology and virulence assessment of Aspergillus fumigatus isolates from white stork chicks and their environment

artículo científico publicado en 2010

Multifactorial induction of an orphan PKS-NRPS gene cluster in Aspergillus terreus

artículo científico publicado en 2011

Murine Infection Models for Aspergillus terreus Pulmonary Aspergillosis Reveal Long-term Persistence of Conidia and Liver Degeneration

article

Nutrient acquisition by pathogenic fungi: nutrient availability, pathway regulation, and differences in substrate utilization.

artículo científico publicado en 2011

On the mechanism of action of the antifungal agent propionate.

artículo científico publicado en 2004

Oxidation of propionate to pyruvate in Escherichia coli. Involvement of methylcitrate dehydratase and aconitase

artículo científico publicado en 2002

Persistence versus escape: Aspergillus terreus and Aspergillus fumigatus employ different strategies during interactions with macrophages

artículo científico publicado en 2012

Persistence within dendritic cells marks an antifungal evasion and dissemination strategy of Aspergillus terreus

artículo científico publicado en 2017

Phosphorylation is the major mechanism regulating isocitrate lyase activity in Paracoccidioides brasiliensis yeast cells ⬇️

artículo científico publicado el 31 de mayo de 2011

Phylogenetic and phenotypic characterisation of the 3-ketoacyl-CoA thiolase gene family from the opportunistic human pathogenic fungus Candida albicans

artículo científico publicado en 2013

Phytotoxin production in Aspergillus terreus is regulated by independent environmental signals

artículo científico publicado en 2015

Re-characterisation of Saccharomyces cerevisiae Ach1p: fungal CoA-transferases are involved in acetic acid detoxification.

artículo científico publicado en 2009

Reducing hypoxia and inflammation during invasive pulmonary aspergillosis by targeting the Interleukin-1 receptor

artículo científico publicado en 2016

Sensitive bioluminescence imaging of fungal dissemination to the brain in mouse models of cryptococcosis

artículo científico publicado en 2019

Terrein biosynthesis in Aspergillus terreus and its impact on phytotoxicity

artículo científico publicado en 2014

The fungal α‐aminoadipate pathway for lysine biosynthesis requires two enzymes of the aconitase family for the isomerization of homocitrate to homoisocitrate ⬇️

artículo científico publicado el 6 de noviembre de 2012

The glycolytic enzyme enolase represents a plasminogen-binding protein on the surface of a wide variety of medically important fungal species

artículo científico publicado en 2015

Two novel species of arctic-alpine lichen-forming fungi (Ascomycota, Megasporaceae) from the Deosai Plains, Pakistan

artículo científico publicado en 2024

Widespread Inter- and Intra-Domain Horizontal Gene Transfer of d-Amino Acid Metabolism Enzymes in Eukaryotes

artículo científico publicado en 2016

Lista de obras de Matthias Brock

A Non-canonical Melanin Biosynthesis Pathway Protects Aspergillus terreus Conidia from Environmental Stress ⬇️

A highly conserved basidiomycete peptide synthetase produces a trimeric hydroxamate siderophore ⬇️

A multimodal imaging approach enables in vivo assessment of antifungal treatment in a mouse model of invasive pulmonary aspergillosis.

A new high-performance heterologous fungal expression system based on regulatory elements from the Aspergillus terreus terrein gene cluster.

ATNT: an enhanced system for expression of polycistronic secondary metabolite gene clusters in Aspergillus niger

Acryloyl-CoA reductase from Clostridium propionicum. An enzyme complex of propionyl-CoA dehydrogenase and electron-transferring flavoprotein.

Analysis of the regulation, expression, and localisation of the isocitrate lyase from Aspergillus fumigatus, a potential target for antifungal drug development.

Application of bioluminescence imaging for in vivo monitoring of fungal infections.

Aspergillus nidulans DigA, a potential homolog of Saccharomyces cerevisiae Pep3 (Vps18), is required for nuclear migration, mitochondrial morphology and polarized growth.

Aspergillus terreus Species Complex

Assessment of efficacy of antifungals against Aspergillus fumigatus: value of real-time bioluminescence imaging.

Back to the roots.

Bioluminescent Aspergillus fumigatus, a new tool for drug efficiency testing and in vivo monitoring of invasive aspergillosis ⬇️

Bringing light into the dark site of infection

Candida albicans Hap43 Domains Are Required under Iron Starvation but Not Excess.

Candida albicans scavenges host zinc via Pra1 during endothelial invasion ⬇️

Candida albicans utilizes a modified β-oxidation pathway for the degradation of toxic propionyl-CoA.

Candida glabrata tryptophan-based pigment production via the Ehrlich pathway

Characterisation of the laccase-encoding gene abr2 of the dihydroxynaphthalene-like melanin gene cluster of Aspergillus fumigatus

Characterization of an acyl-CoA: carboxylate CoA-transferase from Aspergillus nidulans involved in propionyl-CoA detoxification.

Connection of propionyl-CoA metabolism to polyketide biosynthesis in Aspergillus nidulans.

Crystal Structure of 2-Methylisocitrate Lyase (PrpB) from Escherichia coli and Modelling of its Ligand Bound Active Centre ⬇️

DIGE enables the detection of a putative serum biomarker of fungal origin in a mouse model of invasive aspergillosis

Duality of liver and kidney lesions after systemic infection of immunosuppressed and immunocompetent mice with Aspergillus fumigatus.

Dynamic Immune Cell Recruitment After Murine Pulmonary Aspergillus fumigatus Infection under Different Immunosuppressive Regimens

Embryonated eggs as an alternative infection model to investigate Aspergillus fumigatus virulence

Encapsulation of Antifungals in Micelles Protects Candida albicans during Gall-Bladder Infection.

Environmental dimensionality controls the interaction of phagocytes with the pathogenic fungi Aspergillus fumigatus and Candida albicans

Evaluation of lysine biosynthesis as an antifungal drug target: biochemical characterization of Aspergillus fumigatus homocitrate synthase and virulence studies

Exploring metabolic pathways in genome-scale networks via generating flux modes

Fungal metabolism in host niches.

Gene acquisition, duplication and metabolic specification: the evolution of fungal methylisocitrate lyases

Generation and phenotypic characterization of Aspergillus nidulans methylisocitrate lyase deletion mutants: methylisocitrate inhibits growth and conidiation.

Hybrid in silico/in vitro target fishing to assign function to “orphan” compounds of food origin – The case of the fungal metabolite atromentin

Illuminating fungal infections with bioluminescence.

In vivo bioluminescence imaging and histopathopathologic analysis reveal distinct roles for resident and recruited immune effector cells in defense against invasive aspergillosis

In vivo imaging of disseminated murine Candida albicans infection reveals unexpected host sites of fungal persistence during antifungal therapy

Infection-Mediated Priming of Phagocytes Protects against Lethal Secondary Aspergillus fumigatus Challenge

Lipid components of bile increase the protective effect of conjugated bile salts against antifungal drugs.

Longitudinal multimodal imaging-compatible mouse model of triazole-sensitive and -resistant invasive pulmonary aspergillosis

Lysine biosynthesis in microbes: relevance as drug target and prospects for β-lactam antibiotics production.

Methylcitrate cycle activation during adaptation of Fusarium solani and Fusarium verticillioides to propionyl-CoA-generating carbon sources.

Methylcitrate synthase from Aspergillus fumigatus is essential for manifestation of invasive aspergillosis.

Methylcitrate synthase from Aspergillus fumigatus. Propionyl-CoA affects polyketide synthesis, growth and morphology of conidia.

Molecular epidemiology and virulence assessment of Aspergillus fumigatus isolates from white stork chicks and their environment

Multifactorial induction of an orphan PKS-NRPS gene cluster in Aspergillus terreus

Murine Infection Models for Aspergillus terreus Pulmonary Aspergillosis Reveal Long-term Persistence of Conidia and Liver Degeneration

Nutrient acquisition by pathogenic fungi: nutrient availability, pathway regulation, and differences in substrate utilization.

On the mechanism of action of the antifungal agent propionate.

Oxidation of propionate to pyruvate in Escherichia coli. Involvement of methylcitrate dehydratase and aconitase

Persistence versus escape: Aspergillus terreus and Aspergillus fumigatus employ different strategies during interactions with macrophages

Persistence within dendritic cells marks an antifungal evasion and dissemination strategy of Aspergillus terreus

Phosphorylation is the major mechanism regulating isocitrate lyase activity in Paracoccidioides brasiliensis yeast cells ⬇️

Phylogenetic and phenotypic characterisation of the 3-ketoacyl-CoA thiolase gene family from the opportunistic human pathogenic fungus Candida albicans

Phytotoxin production in Aspergillus terreus is regulated by independent environmental signals

Re-characterisation of Saccharomyces cerevisiae Ach1p: fungal CoA-transferases are involved in acetic acid detoxification.

Reducing hypoxia and inflammation during invasive pulmonary aspergillosis by targeting the Interleukin-1 receptor

Sensitive bioluminescence imaging of fungal dissemination to the brain in mouse models of cryptococcosis

Terrein biosynthesis in Aspergillus terreus and its impact on phytotoxicity

The fungal α‐aminoadipate pathway for lysine biosynthesis requires two enzymes of the aconitase family for the isomerization of homocitrate to homoisocitrate ⬇️

The glycolytic enzyme enolase represents a plasminogen-binding protein on the surface of a wide variety of medically important fungal species

Two novel species of arctic-alpine lichen-forming fungi (Ascomycota, Megasporaceae) from the Deosai Plains, Pakistan

Widespread Inter- and Intra-Domain Horizontal Gene Transfer of d-Amino Acid Metabolism Enzymes in Eukaryotes