Lista de obras - Maria J Sanz - Dominio Público Uruguay

3,4-Dihydroxy- and 3,4-methylenedioxy- phenanthrene-type alkaloids with high selectivity for D2 dopamine receptor.

artículo científico publicado en 2013

A hypotensive procyanidin-glycoside from Rhamnus lycioides ssp. lycioides.

artículo científico publicado en 1990

A small molecule, orally active, alpha4beta1/alpha4beta7 dual antagonist reduces leukocyte infiltration and airway hyper-responsiveness in an experimental model of allergic asthma in Brown Norway rats.

artículo científico publicado en 2006

A study of the novel anti-inflammatory agent florifenine topical anti-inflammatory activity and influence on arachidonic acid metabolism and neutrophil functions

artículo científico publicado en 1995

Activation of PPARbeta/delta inhibits leukocyte recruitment, cell adhesion molecule expression, and chemokine release.

artículo científico publicado en 2009

An anti-platelet-endothelial cell adhesion molecule-1 antibody inhibits leukocyte extravasation from mesenteric microvessels in vivo by blocking the passage through the basement membrane

artículo científico publicado en 1996

Angiotensin II induces leukocyte-endothelial cell interactions in vivo via AT(1) and AT(2) receptor-mediated P-selectin upregulation

artículo científico publicado en 2000

Angiotensin II induces neutrophil accumulation in vivo through generation and release of CXC chemokines

scientific article published on 29 November 2004

Antihypertensive action of a procyanidin glycoside from Rhamnus lycioides

scientific article published on 01 January 1991

Arterial and venous endothelia display differential functional fractalkine (CX3CL1) expression by angiotensin-II.

artículo científico publicado en 2012

Avarol and avarone, two new anti-inflammatory agents of marine origin

scientific article published on 01 February 1994

Budlein A from Viguiera robusta inhibits leukocyte-endothelial cell interactions, adhesion molecule expression and inflammatory mediators release.

artículo científico publicado en 2009

CX3CR1/CX3CL1 Axis Mediates Platelet-Leukocyte Adhesion to Arterial Endothelium in Younger Patients with a History of Idiopathic Deep Vein Thrombosis

artículo científico publicado en 2018

CXCR2 blockade impairs angiotensin II-induced CC chemokine synthesis and mononuclear leukocyte infiltration

scientific journal article

Changes in CDKN2A/2B expression associate with T-cell phenotype modulation in atherosclerosis and type 2 diabetes mellitus

artículo científico publicado en 2018

Chemical variations in the essential oil of Sideritis tragoriganum

artículo científico publicado en 2000

Chromone and phenanthrene alkaloids from Dennettia tripetala ⬇️

artículo científico publicado en 2002

Cigarette Smoke Increases Endothelial CXCL16-Leukocyte CXCR6 Adhesion In Vitro and In Vivo. Potential Consequences in Chronic Obstructive Pulmonary Disease.

artículo científico publicado en 2017

Combined sub-optimal doses of rosuvastatin and bexarotene impair angiotensin II-induced arterial mononuclear cell adhesion through inhibition of Nox5 signaling pathways and increased RXR/PPARα and RXR/PPARγ interactions.

artículo científico publicado en 2015

Combined treatment with bexarotene and rosuvastatin reduces angiotensin-II-induced abdominal aortic aneurysm in apoE(-/-) mice and angiogenesis.

artículo científico publicado en 2015

Contributions of ACE and mast cell chymase to endogenous angiotensin II generation and leucocyte recruitment in vivo.

artículo científico publicado en 2011

Coronary Serum Obtained After Myocardial Infarction Induces Angiogenesis and Microvascular Obstruction Repair. Role of Hypoxia-inducible Factor-1A.

artículo científico publicado en 2017

Critical role of fractalkine (CX3CL1) in cigarette smoke-induced mononuclear cell adhesion to the arterial endothelium.

artículo científico publicado en 2012

Cyclic AMP elevating agents and nitric oxide modulate angiotensin II-induced leukocyte-endothelial cell interactions in vivo

artículo científico publicado en 2001

Differential effects of the PAF receptor antagonist UK-74,505 on neutrophil and eosinophil accumulation in guinea-pig skin.

artículo científico publicado en 1994

Disruption of the CCL1-CCR8 axis inhibits vascular Treg recruitment and function and promotes atherosclerosis in mice

artículo científico publicado en 2019

Dopaminergic isoquinolines with hexahydrocyclopenta[ij]-isoquinolines as D2-like selective ligands.

artículo científico publicado en 2016

Dynamics and implications of circulating anti-angiogenic VEGF-A165b isoform in patients with ST-elevation myocardial infarction.

artículo científico publicado en 2017

Effect of bakuchiol on leukocyte functions and some inflammatory responses in mice

artículo científico publicado en 1996

Effect of boldine, secoboldine, and boldine methine on angiotensin II-induced neutrophil recruitment in vivo.

artículo científico publicado en 2005

Effect of chondroitin sulphate on synovitis of knee osteoarthritic patients.

artículo científico publicado en 2017

Effect of two phenanthrene alkaloids on angiotensin II-induced leukocyte-endothelial cell interactions in vivo.

artículo científico publicado en 2003

Effects of flavonoids on Naja naja and human recombinant synovial phospholipases A2 and inflammatory responses in mice.

artículo científico publicado en 1994

Effects of marine 2-polyprenyl-1,4-hydroquinones on phospholipase A2 activity and some inflammatory responses

artículo científico publicado en 1995

Effects of phenolic compounds on bromobenzene-mediated hepatotoxicity in mice

scientific article published on 01 March 1993

Efficient synthesis of hexahydroindenopyridines and their potential as melatoninergic ligands.

artículo científico publicado en 2014

Endothelin-1 causes P-selectin-dependent leukocyte rolling and adhesion within rat mesenteric microvessels

artículo científico publicado en 1999

Erythromycin exerts in vivo anti-inflammatory activity downregulating cell adhesion molecule expression.

artículo científico publicado en 2005

Estrogens inhibit angiotensin II-induced leukocyte-endothelial cell interactions in vivo via rapid endothelial nitric oxide synthase and cyclooxygenase activation.

artículo científico publicado en 2002

Functional role of endothelial CXCL16/CXCR6-platelet-leucocyte axis in angiotensin II-associated metabolic disorders

scientific article published on 01 November 2018

Gastric mucosal resistance to acute injury in experimental portal hypertension

artículo científico publicado en 2001

Hepatic lipase deficiency produces glucose intolerance, inflammation and hepatic steatosis.

artículo científico publicado en 2015

Hepatic lipase inactivation decreases atherosclerosis in insulin resistance by reducing LIGHT/Lymphotoxin β-Receptor pathway.

artículo científico publicado en 2016

Human eotaxin induces alpha 4 and beta 2 integrin-dependent eosinophil accumulation in rat skin in vivo: delayed generation of eotaxin in response to IL-4

scientific journal article

IL-1 is a potent inducer of eosinophil accumulation in rat skin. Inhibition of response by a platelet-activating factor antagonist and an anti-human IL-8 antibody

scientific article published on 01 February 1995

IL-4-induced eosinophil accumulation in rat skin is dependent on endogenous TNF-alpha and alpha 4 integrin/VCAM-1 adhesion pathways.

artículo científico publicado en 1998

Increased dosage of Ink4/Arf protects against glucose intolerance and insulin resistance associated with aging.

artículo científico publicado en 2012

Inflammation determines the pro-adhesive properties of high extracellular d-glucose in human endothelial cells in vitro and rat microvessels in vivo

artículo científico publicado en 2010

Influence of a series of natural flavonoids on free radical generating systems and oxidative stress

artículo científico publicado en 1994

Inhibition of inflammatory responses by epitaondiol and other marine natural products

artículo científico publicado en 1995

Inhibitory effects of N-acetylcysteine on the functional responses of human eosinophils in vitro

artículo científico publicado en 2007

Ink4/Arf locus restores glucose tolerance and insulin sensitivity by reducing hepatic steatosis and inflammation in mice with impaired IRS2-dependent signalling.

artículo científico publicado en 2015

Insulin resistance aggravates atherosclerosis by reducing vascular smooth muscle cell survival and increasing CX3CL1/CX3CR1 axis.

artículo científico publicado en 2014

Intravital Microscopy in the Cremaster Muscle Microcirculation for Endothelial Dysfunction Studies.

artículo científico publicado en 2015

Invariant natural killer T cells act as an extravascular cytotoxic barrier for joint-invading Lyme Borrelia.

artículo científico publicado en 2014

Isolation and hypotensive activity of a polymeric procyanidin fraction from Pistacia lentiscus L

scientific article published on 01 June 1992

L-NAME induces direct arteriolar leukocyte adhesion, which is mainly mediated by angiotensin-II.

artículo científico publicado en 2005

L-selectin regulates human neutrophil transendothelial migration

scientific article published on 06 January 2021

Leukotriene B4-loaded microspheres: a new therapeutic strategy to modulate cell activation

artículo científico publicado en 2008

Map3k8 Modulates Monocyte State and Atherogenesis in ApoE-/- Mice.

artículo científico publicado en 2016

Mechanisms of gastroprotection by transdermal nitroglycerin in the rat.

artículo científico publicado en 1999

Menopause and ovariectomy cause a low grade of systemic inflammation that may be prevented by chronic treatment with low doses of estrogen or losartan.

artículo científico publicado en 2009

Modulatory effects of N-acetyl-L-cysteine on human eosinophil apoptosis

artículo científico publicado en 2007

Molecular mechanisms of NET formation and degradation revealed by intravital imaging in the liver vasculature.

artículo científico publicado en 2015

Morelloflavone, a novel biflavonoid inhibitor of human secretory phospholipase A2 with anti-inflammatory activity.

artículo científico publicado en 1997

Neutrophil chemotaxis

artículo científico publicado en 2018

Neutrophil-active chemokines in in vivo imaging of neutrophil trafficking.

artículo científico

New Alkaloid Antibiotics That Target the DNA Topoisomerase I of Streptococcus pneumoniae ⬇️

artículo científico publicado el 17 de diciembre de 2010

Novel Immune Features of the Systemic Inflammation Associated with Primary Hypercholesterolemia: Changes in Cytokine/Chemokine Profile, Increased Platelet and Leukocyte Activation

scientific article published on 22 December 2018

Novel isoquinoline derivatives as antimicrobial agents

scientific article published on 02 April 2013

PPARβ activation restores the high glucose-induced impairment of insulin signalling in endothelial cells

artículo científico publicado en 2014

Pharmacological actions of a new procyanidin polymer from Pistacia lentiscus L

scientific article published on 01 February 1993

Polycerasoidol, a Natural Prenylated Benzopyran with a Dual PPARα/PPARγ Agonist Activity and Anti-inflammatory Effect

scientific article published on 03 July 2019

Prostaglandin E(2)-loaded microspheres as strategy to inhibit phagocytosis and modulate inflammatory mediators release.

artículo científico publicado en 2008

Reactive oxygen species (ROS) generation inhibited by aporphine and phenanthrene alkaloids semi-synthesized from natural boldine.

artículo científico publicado en 2004

Retinoid X receptor agonists impair arterial mononuclear cell recruitment through peroxisome proliferator-activated receptor-γ activation.

artículo científico publicado en 2012

Roflumilast inhibits leukocyte-endothelial cell interactions, expression of adhesion molecules and microvascular permeability.

artículo científico publicado en 2007

SGLT-2 (Sodium-Glucose Cotransporter 2) Inhibition Reduces Ang II (Angiotensin II)-Induced Dissecting Abdominal Aortic Aneurysm in ApoE (Apolipoprotein E) Knockout Mice

artículo científico publicado en 2019

Synthesis and Pharmacological Evaluation of 2'-Hydroxychalcones and Flavones as Inhibitors of Inflammatory Mediators Generation

artículo científico publicado en 1995

Synthesis and antibacterial activities of cadiolides A, B and C and analogues

artículo científico publicado en 2015

Synthesis and biological evaluation of sphingosine kinase 2 inhibitors with anti-inflammatory activity

scientific article published on 16 January 2019

Synthesis of hexahydrocyclopenta[ij]isoquinolines as a new class of dopaminergic agents.

artículo científico publicado en 2014

Synthesis of pyrido[2,1-a]isoquinolin-4-ones and oxazino[2,3-a]isoquinolin-4-ones: new inhibitors of mitochondrial respiratory chain.

artículo científico publicado en 2013

Systemic Inflammation in Metabolic Syndrome: Increased Platelet and Leukocyte Activation, and Key Role of CX3CL1/CX3CR1 and CCL2/CCR2 Axes in Arterial Platelet-Proinflammatory Monocyte Adhesion.

artículo científico publicado en 2019

Taurine chloramine inhibits functional responses of human eosinophils in vitro.

artículo científico publicado en 2009

Tetrahydroisoquinolines functionalized with carbamates as selective ligands of D2 dopamine receptor

artículo científico publicado en 2017

The angiotensin-(1-7)/Mas receptor axis protects from endothelial cell senescence via klotho and Nrf2 activation

artículo científico publicado en 2019

Topical anti-inflammatory activity of some Mediterranean marine species

artículo científico publicado en 1992

Trans- but not cis-resveratrol impairs angiotensin-II-mediated vascular inflammation through inhibition of NF-κB activation and peroxisome proliferator-activated receptor-gamma upregulation.

artículo científico publicado en 2010

Tumor necrosis factor alpha-induced eosinophil accumulation in rat skin is dependent on alpha4 integrin/vascular cell adhesion molecule-1 adhesion pathways

scientific article published on 01 November 1997

Upregulation of angiostatic chemokines IP-10/CXCL10 and I-TAC/CXCL11 in human obesity and their implication for adipose tissue angiogenesis.

artículo científico publicado en 2018

Vitamin D Receptor Activation Reduces Angiotensin-II-Induced Dissecting Abdominal Aortic Aneurysm in Apolipoprotein E-Knockout Mice

artículo científico publicado en 2016

Lista de obras de Maria J Sanz

3,4-Dihydroxy- and 3,4-methylenedioxy- phenanthrene-type alkaloids with high selectivity for D2 dopamine receptor.

A hypotensive procyanidin-glycoside from Rhamnus lycioides ssp. lycioides.

A small molecule, orally active, alpha4beta1/alpha4beta7 dual antagonist reduces leukocyte infiltration and airway hyper-responsiveness in an experimental model of allergic asthma in Brown Norway rats.

A study of the novel anti-inflammatory agent florifenine topical anti-inflammatory activity and influence on arachidonic acid metabolism and neutrophil functions

Activation of PPARbeta/delta inhibits leukocyte recruitment, cell adhesion molecule expression, and chemokine release.

An anti-platelet-endothelial cell adhesion molecule-1 antibody inhibits leukocyte extravasation from mesenteric microvessels in vivo by blocking the passage through the basement membrane

Angiotensin II induces leukocyte-endothelial cell interactions in vivo via AT(1) and AT(2) receptor-mediated P-selectin upregulation

Angiotensin II induces neutrophil accumulation in vivo through generation and release of CXC chemokines

Antihypertensive action of a procyanidin glycoside from Rhamnus lycioides

Arterial and venous endothelia display differential functional fractalkine (CX3CL1) expression by angiotensin-II.

Avarol and avarone, two new anti-inflammatory agents of marine origin

Budlein A from Viguiera robusta inhibits leukocyte-endothelial cell interactions, adhesion molecule expression and inflammatory mediators release.

CX3CR1/CX3CL1 Axis Mediates Platelet-Leukocyte Adhesion to Arterial Endothelium in Younger Patients with a History of Idiopathic Deep Vein Thrombosis

CXCR2 blockade impairs angiotensin II-induced CC chemokine synthesis and mononuclear leukocyte infiltration

Changes in CDKN2A/2B expression associate with T-cell phenotype modulation in atherosclerosis and type 2 diabetes mellitus

Chemical variations in the essential oil of Sideritis tragoriganum

Chromone and phenanthrene alkaloids from Dennettia tripetala ⬇️

Cigarette Smoke Increases Endothelial CXCL16-Leukocyte CXCR6 Adhesion In Vitro and In Vivo. Potential Consequences in Chronic Obstructive Pulmonary Disease.

Combined sub-optimal doses of rosuvastatin and bexarotene impair angiotensin II-induced arterial mononuclear cell adhesion through inhibition of Nox5 signaling pathways and increased RXR/PPARα and RXR/PPARγ interactions.

Combined treatment with bexarotene and rosuvastatin reduces angiotensin-II-induced abdominal aortic aneurysm in apoE(-/-) mice and angiogenesis.

Contributions of ACE and mast cell chymase to endogenous angiotensin II generation and leucocyte recruitment in vivo.

Coronary Serum Obtained After Myocardial Infarction Induces Angiogenesis and Microvascular Obstruction Repair. Role of Hypoxia-inducible Factor-1A.

Critical role of fractalkine (CX3CL1) in cigarette smoke-induced mononuclear cell adhesion to the arterial endothelium.

Cyclic AMP elevating agents and nitric oxide modulate angiotensin II-induced leukocyte-endothelial cell interactions in vivo

Differential effects of the PAF receptor antagonist UK-74,505 on neutrophil and eosinophil accumulation in guinea-pig skin.

Disruption of the CCL1-CCR8 axis inhibits vascular Treg recruitment and function and promotes atherosclerosis in mice

Dopaminergic isoquinolines with hexahydrocyclopenta[ij]-isoquinolines as D2-like selective ligands.

Dynamics and implications of circulating anti-angiogenic VEGF-A165b isoform in patients with ST-elevation myocardial infarction.

Effect of bakuchiol on leukocyte functions and some inflammatory responses in mice

Effect of boldine, secoboldine, and boldine methine on angiotensin II-induced neutrophil recruitment in vivo.

Effect of chondroitin sulphate on synovitis of knee osteoarthritic patients.

Effect of two phenanthrene alkaloids on angiotensin II-induced leukocyte-endothelial cell interactions in vivo.

Effects of flavonoids on Naja naja and human recombinant synovial phospholipases A2 and inflammatory responses in mice.

Effects of marine 2-polyprenyl-1,4-hydroquinones on phospholipase A2 activity and some inflammatory responses

Effects of phenolic compounds on bromobenzene-mediated hepatotoxicity in mice

Efficient synthesis of hexahydroindenopyridines and their potential as melatoninergic ligands.

Endothelin-1 causes P-selectin-dependent leukocyte rolling and adhesion within rat mesenteric microvessels

Erythromycin exerts in vivo anti-inflammatory activity downregulating cell adhesion molecule expression.

Estrogens inhibit angiotensin II-induced leukocyte-endothelial cell interactions in vivo via rapid endothelial nitric oxide synthase and cyclooxygenase activation.

Functional role of endothelial CXCL16/CXCR6-platelet-leucocyte axis in angiotensin II-associated metabolic disorders

Gastric mucosal resistance to acute injury in experimental portal hypertension

Hepatic lipase deficiency produces glucose intolerance, inflammation and hepatic steatosis.

Hepatic lipase inactivation decreases atherosclerosis in insulin resistance by reducing LIGHT/Lymphotoxin β-Receptor pathway.

Human eotaxin induces alpha 4 and beta 2 integrin-dependent eosinophil accumulation in rat skin in vivo: delayed generation of eotaxin in response to IL-4

IL-1 is a potent inducer of eosinophil accumulation in rat skin. Inhibition of response by a platelet-activating factor antagonist and an anti-human IL-8 antibody

IL-4-induced eosinophil accumulation in rat skin is dependent on endogenous TNF-alpha and alpha 4 integrin/VCAM-1 adhesion pathways.

Increased dosage of Ink4/Arf protects against glucose intolerance and insulin resistance associated with aging.

Inflammation determines the pro-adhesive properties of high extracellular d-glucose in human endothelial cells in vitro and rat microvessels in vivo

Influence of a series of natural flavonoids on free radical generating systems and oxidative stress

Inhibition of inflammatory responses by epitaondiol and other marine natural products

Inhibitory effects of N-acetylcysteine on the functional responses of human eosinophils in vitro

Ink4/Arf locus restores glucose tolerance and insulin sensitivity by reducing hepatic steatosis and inflammation in mice with impaired IRS2-dependent signalling.

Insulin resistance aggravates atherosclerosis by reducing vascular smooth muscle cell survival and increasing CX3CL1/CX3CR1 axis.

Intravital Microscopy in the Cremaster Muscle Microcirculation for Endothelial Dysfunction Studies.

Invariant natural killer T cells act as an extravascular cytotoxic barrier for joint-invading Lyme Borrelia.

Isolation and hypotensive activity of a polymeric procyanidin fraction from Pistacia lentiscus L

L-NAME induces direct arteriolar leukocyte adhesion, which is mainly mediated by angiotensin-II.

L-selectin regulates human neutrophil transendothelial migration

Leukotriene B4-loaded microspheres: a new therapeutic strategy to modulate cell activation

Map3k8 Modulates Monocyte State and Atherogenesis in ApoE-/- Mice.

Mechanisms of gastroprotection by transdermal nitroglycerin in the rat.

Menopause and ovariectomy cause a low grade of systemic inflammation that may be prevented by chronic treatment with low doses of estrogen or losartan.

Modulatory effects of N-acetyl-L-cysteine on human eosinophil apoptosis

Molecular mechanisms of NET formation and degradation revealed by intravital imaging in the liver vasculature.

Morelloflavone, a novel biflavonoid inhibitor of human secretory phospholipase A2 with anti-inflammatory activity.

Neutrophil chemotaxis

Neutrophil-active chemokines in in vivo imaging of neutrophil trafficking.

New Alkaloid Antibiotics That Target the DNA Topoisomerase I of Streptococcus pneumoniae ⬇️

Novel Immune Features of the Systemic Inflammation Associated with Primary Hypercholesterolemia: Changes in Cytokine/Chemokine Profile, Increased Platelet and Leukocyte Activation

Novel isoquinoline derivatives as antimicrobial agents

PPARβ activation restores the high glucose-induced impairment of insulin signalling in endothelial cells

Pharmacological actions of a new procyanidin polymer from Pistacia lentiscus L

Polycerasoidol, a Natural Prenylated Benzopyran with a Dual PPARα/PPARγ Agonist Activity and Anti-inflammatory Effect

Prostaglandin E(2)-loaded microspheres as strategy to inhibit phagocytosis and modulate inflammatory mediators release.

Reactive oxygen species (ROS) generation inhibited by aporphine and phenanthrene alkaloids semi-synthesized from natural boldine.

Retinoid X receptor agonists impair arterial mononuclear cell recruitment through peroxisome proliferator-activated receptor-γ activation.

Roflumilast inhibits leukocyte-endothelial cell interactions, expression of adhesion molecules and microvascular permeability.

SGLT-2 (Sodium-Glucose Cotransporter 2) Inhibition Reduces Ang II (Angiotensin II)-Induced Dissecting Abdominal Aortic Aneurysm in ApoE (Apolipoprotein E) Knockout Mice

Synthesis and Pharmacological Evaluation of 2'-Hydroxychalcones and Flavones as Inhibitors of Inflammatory Mediators Generation