Lista de obras - Marcelo A Comini - Dominio Público Uruguay

1H, 13C and 15N resonance assignment of the cytosolic dithiol glutaredoxin 1 from the pathogen Trypanosoma brucei

artículo científico publicado en 2015

1H, 13C and 15N resonance assignment of the mature form of monothiol glutaredoxin 1 from the pathogen Trypanosoma brucei

artículo científico publicado en 2014

5-Substituted 3-chlorokenpaullone derivatives are potent inhibitors of Trypanosoma brucei bloodstream forms

artículo científico publicado en 2016

A glutaredoxin in the mitochondrial intermembrane space has stage-specific functions in the thermo-tolerance and proliferation of African trypanosomes

artículo científico publicado en 2018

A simple, robust, and affordable bioluminescent assay for drug discovery against infective African trypanosomes

scientific article published on 20 January 2020

Alternative Thiol-Based Redox Systems.

artículo científico publicado en 2017

An essential thioredoxin-type protein of Trypanosoma brucei acts as redox-regulated mitochondrial chaperone.

artículo científico publicado en 2019

Antitumor and antiparasitic activity of novel ruthenium compounds with polycyclic aromatic ligands

artículo científico publicado en 2015

Binding Mode and Selectivity of Steroids towards Glucose-6-phosphate Dehydrogenase from the Pathogen Trypanosoma cruzi.

artículo científico publicado en 2016

Biosynthesis of trypanothione in Trypanosoma brucei brucei.

artículo científico publicado en 2003

Cytosolic peroxidases protect the lysosome of bloodstream African trypanosomes from iron-mediated membrane damage

artículo científico publicado en 2014

Cytotoxic interactions of methylene blue with trypanosomatid-specific disulfide reductases and their dithiol products.

artículo científico publicado en 2008

Determination of acidity and nucleophilicity in thiols by reaction with monobromobimane and fluorescence detection

artículo científico publicado en 2013

Diglycosyl diselenides alter redox homeostasis and glucose consumption of infective African trypanosomes

artículo científico publicado en 2017

Evaluation of commercial enzyme-linked immunosorbent assay kits for detection of tuberculosis in Argentinean population.

artículo científico publicado en 2004

Expression, crystallization and preliminary X-ray crystallographic analysis of glucose-6-phosphate dehydrogenase from the human pathogen Trypanosoma cruzi in complex with substrate

artículo científico publicado en 2011

Genetic and chemical analyses reveal that trypanothione synthetase but not glutathionylspermidine synthetase is essential for Leishmania infantum

artículo científico publicado en 2014

Glucose-6-Phosphate Dehydrogenase from the Human Pathogen Trypanosoma cruzi Evolved Unique Structural Features to Support Efficient Product Formation

artículo científico publicado en 2019

Glutaredoxin-deficiency confers bloodstream Trypanosoma brucei with improved thermotolerance

artículo científico publicado en 2016

Identification of Novel Chemical Scaffolds Inhibiting Trypanothione Synthetase from Pathogenic Trypanosomatids

artículo científico publicado en 2016

Identification of novel bacterial plasminogen-binding proteins in the human pathogen Mycobacterium tuberculosis

scientific journal article

In vitro activity and mode of action of distamycin analogues against African trypanosomes.

artículo científico publicado en 2016

Iron–Sulfur Cluster Binding by Mitochondrial Monothiol Glutaredoxin-1 of Trypanosoma brucei : Molecular Basis of Iron–Sulfur Cluster Coordination and Relevance for Parasite Infectivity

artículo científico publicado en 2013

Kinetic studies reveal a key role of a redox-active glutaredoxin in the evolution of the thiol-redox metabolism of trypanosomatid parasites

scientific article published on 28 December 2018

Lipoamide dehydrogenase is essential for both bloodstream and procyclic Trypanosoma brucei ⬇️

artículo científico publicado el 4 de julio de 2011

Measurement and meaning of cellular thiol:disufhide redox status

artículo científico

Mechanistic and biological characterisation of novel N5-substituted paullones targeting the biosynthesis of trypanothione in Leishmania

artículo científico publicado en 2020

Mono- and dithiol glutaredoxins in the trypanothione-based redox metabolism of pathogenic trypanosomes.

artículo científico

New heterobimetallic ferrocenyl derivatives are promising antitrypanosomal agents

artículo científico publicado en 2019

New organoruthenium complexes with bioactive thiosemicarbazones as co-ligands: potential anti-trypanosomal agents.

artículo científico publicado en 2011

New red-shifted fluorescent biosensor for monitoring intracellular redox changes

scientific article published on 05 February 2019

Novel ruthenium(II) cyclopentadienyl thiosemicarbazone compounds with antiproliferative activity on pathogenic trypanosomatid parasites.

artículo científico publicado en 2015

Ornithine decarboxylase or gamma-glutamylcysteine synthetase overexpression protects Leishmania (Vianna) guyanensis against antimony.

artículo científico publicado en 2017

Oxidovanadium(IV) and dioxidovanadium(V) complexes of tridentate salicylaldehyde semicarbazones: searching for prospective antitrypanosomal agents

artículo científico publicado en 2013

Polyamine-Based Thiols in Trypanosomatids: Evolution, Protein Structural Adaptations, and Biological Functions.

artículo científico publicado en 2017

Preparative enzymatic synthesis of trypanothione and trypanothione analogues.

artículo científico publicado en 2009

Production of Recombinant Trypanosoma cruzi Antigens in Leishmania tarentolae

artículo científico publicado en 2019

Pt-Fe ferrocenyl compounds with hydroxyquinoline ligands show selective cytotoxicity on highly proliferative cells

scientific article published on 16 July 2019

Selenoproteins of African trypanosomes are dispensable for parasite survival in a mammalian host.

artículo científico publicado en 2016

Synthesis of bicyclic 1,4-thiazepines as novel anti-Trypanosoma brucei brucei agents

scientific article published on 11 June 2019

The Thiol-polyamine Metabolism of Trypanosoma cruzi: Molecular Targets and Drug Repurposing Strategies

scientific article published on 01 January 2019

The lineage-specific, intrinsically disordered N-terminal extension of monothiol glutaredoxin 1 from trypanosomes contains a regulatory region

artículo científico publicado en 2018

Trypanothione synthesis in crithidia revisited.

artículo científico publicado en 2004

Trypanothione synthetase confers growth, survival advantage and resistance to anti-protozoal drugs in Trypanosoma cruzi

article

Lista de obras de Marcelo A Comini

1H, 13C and 15N resonance assignment of the cytosolic dithiol glutaredoxin 1 from the pathogen Trypanosoma brucei

1H, 13C and 15N resonance assignment of the mature form of monothiol glutaredoxin 1 from the pathogen Trypanosoma brucei

5-Substituted 3-chlorokenpaullone derivatives are potent inhibitors of Trypanosoma brucei bloodstream forms

A glutaredoxin in the mitochondrial intermembrane space has stage-specific functions in the thermo-tolerance and proliferation of African trypanosomes

A simple, robust, and affordable bioluminescent assay for drug discovery against infective African trypanosomes

Alternative Thiol-Based Redox Systems.

An essential thioredoxin-type protein of Trypanosoma brucei acts as redox-regulated mitochondrial chaperone.

Antitumor and antiparasitic activity of novel ruthenium compounds with polycyclic aromatic ligands

Binding Mode and Selectivity of Steroids towards Glucose-6-phosphate Dehydrogenase from the Pathogen Trypanosoma cruzi.

Biosynthesis of trypanothione in Trypanosoma brucei brucei.

Cytosolic peroxidases protect the lysosome of bloodstream African trypanosomes from iron-mediated membrane damage

Cytotoxic interactions of methylene blue with trypanosomatid-specific disulfide reductases and their dithiol products.

Determination of acidity and nucleophilicity in thiols by reaction with monobromobimane and fluorescence detection

Diglycosyl diselenides alter redox homeostasis and glucose consumption of infective African trypanosomes

Evaluation of commercial enzyme-linked immunosorbent assay kits for detection of tuberculosis in Argentinean population.

Expression, crystallization and preliminary X-ray crystallographic analysis of glucose-6-phosphate dehydrogenase from the human pathogen Trypanosoma cruzi in complex with substrate

Genetic and chemical analyses reveal that trypanothione synthetase but not glutathionylspermidine synthetase is essential for Leishmania infantum

Glucose-6-Phosphate Dehydrogenase from the Human Pathogen Trypanosoma cruzi Evolved Unique Structural Features to Support Efficient Product Formation

Glutaredoxin-deficiency confers bloodstream Trypanosoma brucei with improved thermotolerance

Identification of Novel Chemical Scaffolds Inhibiting Trypanothione Synthetase from Pathogenic Trypanosomatids

Identification of novel bacterial plasminogen-binding proteins in the human pathogen Mycobacterium tuberculosis

In vitro activity and mode of action of distamycin analogues against African trypanosomes.

Iron–Sulfur Cluster Binding by Mitochondrial Monothiol Glutaredoxin-1 of Trypanosoma brucei : Molecular Basis of Iron–Sulfur Cluster Coordination and Relevance for Parasite Infectivity

Kinetic studies reveal a key role of a redox-active glutaredoxin in the evolution of the thiol-redox metabolism of trypanosomatid parasites

Lipoamide dehydrogenase is essential for both bloodstream and procyclic Trypanosoma brucei ⬇️

Measurement and meaning of cellular thiol:disufhide redox status

Mechanistic and biological characterisation of novel N5-substituted paullones targeting the biosynthesis of trypanothione in Leishmania

Mono- and dithiol glutaredoxins in the trypanothione-based redox metabolism of pathogenic trypanosomes.

New heterobimetallic ferrocenyl derivatives are promising antitrypanosomal agents

New organoruthenium complexes with bioactive thiosemicarbazones as co-ligands: potential anti-trypanosomal agents.

New red-shifted fluorescent biosensor for monitoring intracellular redox changes

Novel ruthenium(II) cyclopentadienyl thiosemicarbazone compounds with antiproliferative activity on pathogenic trypanosomatid parasites.

Ornithine decarboxylase or gamma-glutamylcysteine synthetase overexpression protects Leishmania (Vianna) guyanensis against antimony.

Oxidovanadium(IV) and dioxidovanadium(V) complexes of tridentate salicylaldehyde semicarbazones: searching for prospective antitrypanosomal agents

Polyamine-Based Thiols in Trypanosomatids: Evolution, Protein Structural Adaptations, and Biological Functions.

Preparative enzymatic synthesis of trypanothione and trypanothione analogues.

Production of Recombinant Trypanosoma cruzi Antigens in Leishmania tarentolae

Pt-Fe ferrocenyl compounds with hydroxyquinoline ligands show selective cytotoxicity on highly proliferative cells

Selenoproteins of African trypanosomes are dispensable for parasite survival in a mammalian host.

Synthesis of bicyclic 1,4-thiazepines as novel anti-Trypanosoma brucei brucei agents

The Thiol-polyamine Metabolism of Trypanosoma cruzi: Molecular Targets and Drug Repurposing Strategies

The lineage-specific, intrinsically disordered N-terminal extension of monothiol glutaredoxin 1 from trypanosomes contains a regulatory region

Trypanothione synthesis in crithidia revisited.

Trypanothione synthetase confers growth, survival advantage and resistance to anti-protozoal drugs in Trypanosoma cruzi